Gene, Genome Project and Scientist - Clinical Research Informer

Exa-Cel CRISPR Gene Therapy for Sickle Cell Disease Deemed Safe by FDA Advisory Panel

XTalks

NOVEMBER 3, 2023

After spending almost an entire day deliberating the safety of Vertex Pharmaceuticals’ and CRISPR Therapeutics’ CRISPR-based gene therapy exa-cel for sickle cell disease, a US Food and Drug Administration (FDA) advisory panel appears to be satisfied with what it saw. CRISPR works as genetic scissors to edit parts of the genome.

Gene Therapy

Gene Therapy Gene Gene Editing In-Vivo

Q&A: Gene therapy opportunities from long-read sequencing

Drug Discovery World

SEPTEMBER 20, 2022

Breakthroughs in gene therapy are only possible with an exact understanding of the genetic underpinnings of disease. To develop safe and effective gene therapies, researchers need confidence that genomic data is both complete and accurate. Recent years have seen a great deal of progress in both short- and long-read sequencing.

Gene Therapy

Gene Therapy Gene Genome Genomics

Can genetic data be a magic bullet for drug R&D?

pharmaphorum

JANUARY 24, 2023

Pharma has used this to begin creating targeted treatments, such as gene therapies , which are able to hone in on gene mutations that cause health issues and eradicate or replace the faulty gene. The information gathered from the project is still providing insights today, a decade later.

Genetics

Genetics Drugs Genome Project Biobanking

Why genomic healthcare data matters in the development of new therapies

Drug Discovery World

NOVEMBER 7, 2022

One might argue that this all started getting exciting with the launch of the Human Genome Project, which the National Human Genome Research Institute consider to be one of the greatest scientific feats in history 1. Many of these genes are related to inherited forms of cancer and heart conditions. . The origins .

Genome

Genome Genomics Development Genetics

Genomic projects exploit scale as clinical applications play catch-up

Pharmaceutical Technology

JUNE 30, 2022

Earlier this month, scientists from Cambridge University and the Madrid-based National Cancer Research Center described a novel framework tracking chromosomal instability and copy number changes in particularly deadly cancers.

Genome Project

Genome Project Genome Genomics DNA

COSMIC database matches drugs to cancer mutations

pharmaphorum

MARCH 25, 2021

The COSMIC (Catalogue of Somatic Mutations in Cancer) database, operated by the Wellcome Sanger Institute, grew out of the work of the Cancer Genome Project and has been gathering data on mutations associated with specific cancers for almost 17 years.

Drugs

Drugs Genome Project Genome Genomics

Bioinformatics Jobs: How to Succeed in This Competitive Space

XTalks

APRIL 5, 2021

Bioinformaticians use a combination of mathematics, computer science and biology to help scientists make sense of the data gathered from research projects. The Human Genome Project could not have succeeded without the use of bioinformatics. Bioinformatics Scientist. How to Become a Bioinformatics Scientist.

Bioinformatics

Bioinformatics Engineer Scientist Genome

Searching for answers in rare epilepsy

pharmaphorum

SEPTEMBER 9, 2020

Charlie told pharmaphorum how his search for a genetic cause has led him to straddle the divide between scientist and patient advocate. Everything the 100,000 Genomes Project does has to be rubber-stamped by the patients”. For some people, a job is more than just a job.

Genome

Genome Genomics Genetics Genome Project

The pangenome is making personalised medicine more equitable

Pharmaceutical Technology

JUNE 14, 2023

All that DNA is organised into hereditary units called genes, with humans having about 25,000 genes collectively known as the genome. The Human Genome Project Launched in October 1990, The Human Genome Project sought to sequence the entire human genome using a method called Sanger sequencing.

Genome Project

Genome Project Medicine Genome Genomics

Searching for answers in rare epilepsy

pharmaphorum

SEPTEMBER 9, 2020

Charlie told pharmaphorum how his search for a genetic cause has led him to straddle the divide between scientist and patient advocate. Everything the 100,000 Genomes Project does has to be rubber-stamped by the patients”. For some people, a job is more than just a job.

Genome

Genome Genomics Genetics Genome Project

Where is the drug discovery expertise happening in the UK?

Drug Discovery World

OCTOBER 16, 2023

Dr Salako says there are some clear fields of work associated with different areas, which include: Hertfordshire as a cell and gene therapy hub, with a number of companies in this space clustered around Stevenage. billion in funding. This includes support for export and expansion into new territories as well as for innovation and development.

Drugs

Drugs Life Science Gene Therapy Genome

Junk DNA: How the dark genome is changing RNA therapies

Drug Discovery World

AUGUST 16, 2023

Decoding ‘junk DNA’ The Human Genome Project and subsequent studies discovered that most of our DNA (approximately 98%) does not actually code for proteins, with humans having approximately 20,000 tox 25,000 protein-coding genes.

RNA

RNA Genome Genomics DNA

Nutrigenomics: The Future of Personalized Nutrition

Roots Analysis

AUGUST 31, 2023

According to a study, around 20,000 genes are present in the human body, all of which interact with the nutrients in the food, either directly or indirectly. Nutrigenomics is the science studying the relationship between human genome, nutrition and health. Figure below presents an overview of nutrigenomics.

Genome

Genome Genomics Genetics Gene

A history of blood cancer treatment

pharmaphorum

SEPTEMBER 13, 2022

During this period, Nobel prize-winning German scientist Paul Ehrlich developed his lock-key hypothesis of molecules that specifically bind to cell receptors. Building on the success of cytokine-based immunotherapies, scientists continued to seek other areas where the immune system could be leveraged against tumours.

Genome Project

Genome Project Genome Genomics DNA

The future of genomic medicine: can it fulfil its promises?

pharmaphorum

SEPTEMBER 14, 2020

Here he gives us a deeper look at how genomic medicine is evolving and the barriers that are preventing it from reaching its full potential. Unsurprisingly, in many respects, the human genome turned out to be a lot more complex than was originally thought. Yet, this can be treated simply by administering a type of vitamin B6.

Genome

Genome Genomics Medicine Gene

Women in Science Who Have Paved the Way Forward in Genetics

XTalks

FEBRUARY 11, 2021

The Human Genome Project recently marked 20 years since the publication of the first full sets of human genomic sequences, an endeavor that spanned well over a decade. Today, new next-generation sequencing technologies allow for the sequencing of complex genomes within just a day or two.

Genetics

Genetics DNA Genome Genomics

Clinical Research Informer

Exa-Cel CRISPR Gene Therapy for Sickle Cell Disease Deemed Safe by FDA Advisory Panel

Q&A: Gene therapy opportunities from long-read sequencing

Trending Sources

Can genetic data be a magic bullet for drug R&D?

Why genomic healthcare data matters in the development of new therapies

Genomic projects exploit scale as clinical applications play catch-up

COSMIC database matches drugs to cancer mutations

Bioinformatics Jobs: How to Succeed in This Competitive Space

Searching for answers in rare epilepsy

The pangenome is making personalised medicine more equitable

Searching for answers in rare epilepsy

Where is the drug discovery expertise happening in the UK?

Junk DNA: How the dark genome is changing RNA therapies

Nutrigenomics: The Future of Personalized Nutrition

A history of blood cancer treatment

The future of genomic medicine: can it fulfil its promises?

Women in Science Who Have Paved the Way Forward in Genetics

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