The Pharma Data

JANUARY 4, 2021

officials ramped up efforts to vaccinate more Americans, scientists around the world wrestled with whether it would make sense to delay the second doses everyone will need so more people can be vaccinated more quickly. Each vaccine would still be delivered in two doses given four weeks apart. MONDAY, Jan.

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STAT News

FEBRUARY 22, 2023

Moderna is aiming to build a gene editing franchise powered by some of the same technologies used in its COVID-19 vaccines. The Cambridge biotech company announced Wednesday that it will partner with Life Edit Therapeutics to develop potentially permanent treatments for rare genetic diseases and other conditions.

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Scienmag

SEPTEMBER 1, 2020

Genetic analysis of sequences from more than 27,000 individuals infected with the coronavirus that causes COVID-19 reveals that the virus has mutated minimally since December 2019, suggesting one vaccine would be sufficient to combat global infections.

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pharmaphorum

SEPTEMBER 14, 2020

AstraZeneca has resumed UK trials for its coronavirus vaccine, after the country’s medicines regulator gave the all-clear following a safety scare. Good news for everyone the Oxford vaccine trials are back up and running. We will back our scientists to deliver an effective vaccine as soon as safely possible [link].

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pharmaphorum

SEPTEMBER 17, 2020

US medical experts are reportedly concerned that a neurological side effect picked up in AstraZeneca’s closely-watched COVID-19 vaccine trial could compromise the whole project, as the FDA weighs whether to give the go ahead for US studies to resume. The post US experts stress over safety of AZ’s COVID-19 vaccine appeared first on.

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Drug Discovery World

JANUARY 19, 2024

Clinical trial will test novel inhaled TB vaccine A new study will compare whether giving tuberculosis vaccine by inhalation is better at protecting against tuberculosis (TB) than injection into the skin. Revealed: How Covid-19 variants stay ahead of immune defences Recent SARS-CoV-2 variants such as BA.4

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pharmaphorum

JANUARY 20, 2021

Laboratory studies have confirmed that antibodies stimulated by Pfizer and BioNTech’s COVID-19 vaccine can neutralise the new, more transmissible variant of SARS-CoV-2 identified in the UK. VOC 202012/01 has an unusually high number of genetic changes however, with 10 mutations affecting the spike protein. lineage or VOC 202012/01.

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Scienmag

APRIL 6, 2022

SAN FRANCISCO, CA—April 6, 2022—A vaccine for hepatitis C has eluded scientists for more than 30 years, for several reasons. For one, the virus that causes the disease comes in many genetic forms, complicating the creation of a widely effective vaccine.

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The Pharma Data

FEBRUARY 12, 2022

The discovery, published in Science Translational Medicine, could inform the design of broad-acting vaccines and antibody therapies capable of stopping future coronavirus pandemics. That prospect has spurred efforts towards the development of a pan-beta-coronaviral vaccine or antibody therapy. Source link: [link].

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pharmaphorum

NOVEMBER 9, 2020

As the death toll from COVID19 inexorably mounts, Pfizer and BioNTech have announced that their COVID-19 vaccine candidate is more than 90% effective at countering the disease in an interim analysis. This means that protection is achieved 28 days after the initiation of the vaccination, which consists of a 2-dose schedule.

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Cloudbyz

MAY 22, 2023

The race to create a vaccine for the novel coronavirus, SARS-CoV-2, saw an unprecedented global scientific collaboration. This international effort culminated in the successful clinical trials and subsequent rollout of several effective COVID-19 vaccines in record time. Below, we dive into the key lessons gleaned from this journey.

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STAT News

APRIL 6, 2023

The wholly synthetic mRNA vaccines for Covid-19 saved nearly 20 million lives in just their first year of use, according to data published in 2022 by The Lancet. That success stands as the most prominent example of the power of synthetic biology, a field whose possibilities have excited me since I first heard the term more than 15 years ago.

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XTalks

SEPTEMBER 8, 2020

The company has signed on to help manufacture AstraZeneca’s COVID-19 vaccine candidate, AZD1222, intended to protect against the SARS-CoV-2 novel coronavirus. AMRI is proud to partner with AstraZeneca in pursuit of a vaccine that could protect people against the coronavirus pandemic,” said John Ratliff, CEO of AMRI, in a statement.

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The Pharma Data

NOVEMBER 16, 2020

16, 2020 — Scientists are reporting early success with an experimental herpes vaccine that uses a genetically modified version of the virus. So far, the vaccine has only been tested in lab animals. So far, the vaccine has only been tested in lab animals. MONDAY, Nov.

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XTalks

JANUARY 11, 2023

The new subvariant has also been dubbed “Kraken” by some scientists. Importantly, preliminary data shows that bivalent COVID-19 vaccines that target the parent strain of Omicron should provide protection against XBB.1.5 on the horizon as scientists say the virus appears to be rapidly evolving , mutating faster than most viruses.

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Pharmaceutical Technology

APRIL 20, 2023

Circio aims to develop new circRNA medicines initially for cancer, then plans to expand rapidly into vaccines and gene therapy. The circVec platform is a modular genetic cassette that provides instructions for the generation of multifunctional circRNAs.

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Drug Discovery World

OCTOBER 6, 2023

In celebration of the Nobel Prize for Medicine going to two of the early proponents of mRNA technology for creating therapeutics, Katalin Karikó and Drew Weissman, this week our round-up highlights the importance of genetics, genomics and gene editing in drug discovery.

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Scienmag

FEBRUARY 17, 2021

Messenger RNA (mRNA) vaccines to prevent COVID-19 have made headlines around the world recently, but scientists have also been working on mRNA vaccines to treat or prevent other diseases, including some forms of cancer.

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pharmaphorum

JULY 14, 2021

AstraZeneca and Johnson & Johnson are both exploring ways to modify their COVID-19 vaccines to minimise the risk of severe blood clotting reactions that are seen – albeit rarely – in some people receiving the jabs. Its guideline is due to be published before the end of this month.

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pharmaphorum

JANUARY 26, 2023

We are already seeing an increase in projects exploring population genomics in Africa, the Middle East, and Asia, with initiatives including the GenomeAsia100K Project and the Genome Aggregation Database focusing on capturing genetic data of non-European individuals.

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The Pharma Data

OCTOBER 18, 2021

Northwestern Medicine scientists have shown for the first time that coronavirus vaccines and prior coronavirus infections can provide broad immunity against other, similar coronaviruses. The findings build a rationale for universal coronavirus vaccines that could prove useful in the face of future epidemics.

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Drug Discovery World

JULY 3, 2023

The international study into the pandemic potential of avian flu, which is led by scientists at the MRC-University of Glasgow Centre for Virus Research (CVR), identified the human gene BTN3A3, which is commonly expressed in our airways, as a key human defence against avian flu.

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The Pharma Data

JANUARY 16, 2021

16, 2021 — President-elect Joe Biden described an ambitious national vaccination plan on Friday that will deliver coronavirus vaccines to far more people and invoke a wartime law to boost vaccine production. Even if Biden invokes the Korean War-era Defense Production Act, it may take some time to ease vaccine shortages.

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pharmaphorum

FEBRUARY 1, 2022

1 strain, and there is somewhat conflicting evidence on its ability to evade the protection from vaccines, according to new studies. That increase was seen regardless of the vaccination status of the secondary cases, and there was an increased risk of spread within vaccinated households with BA.2 The new BA.2 1 and 70% for BA.2

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Drug Discovery World

JANUARY 11, 2024

The team, led by University College London (UCL), King’s College London and Moderna scientists, found that mRNA could be used to correct a rare genetic liver disease known as argininosuccinic aciduria in a mouse model. We believe it can now do the same for rare diseases.”

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pharmaphorum

DECEMBER 21, 2020

Moderna and BioNTech, two rising stars in biotech, were in the limelight this year with their pioneering mRNA vaccines against COVID-19. But the tragic events of 2020 have meant these companies have become household names as their trailblazing mRNA vaccines became the first to be approved by regulators against the COVID-19 scourge.

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XTalks

AUGUST 13, 2021

British vaccine developer, Sarah Gilbert, has been honored with a Barbie doll. Gilbert is a professor at Oxford University who helped lead the development of the Oxford/AstraZeneca COVID-19 vaccine. Related: Women in Science Who Have Paved the Way Forward in Genetics. Jaqueline Goes de Jesus is a Brazilian biomedical engineer.

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The Pharma Data

JANUARY 5, 2021

Food and Drug Administration said Monday that any American who gets the Moderna or Pfizer coronavirus vaccines must get two full doses, despite international debate on possible ways to stretch vaccine supply. vaccine effort just as the public is starting to trust the program, Dr. . In the U.K., In the U.K.,

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The Pharma Data

JULY 6, 2021

But HIV’s ability to mutate isn’t unique among RNA viruses – most viruses develop mutations, or changes in their genetic code, over time. He and his team reasoned that the virus would likely mutate, potentially in ways that would allow it to escape both natural and vaccine-induced immunity.

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The Pharma Data

JANUARY 21, 2021

New research into exactly which genetic mutations increase breast cancer risk in women without a family history of the disease may help guide decisions about screening and preventive surgery, doctors say. The two large studies also examined how common these genetic flaws are in the general population, the Associated Press reported.

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The Pharma Data

DECEMBER 18, 2020

Action Follows Thorough Evaluation of Available Safety, Effectiveness, and Manufacturing Quality Information by FDA Career Scientists, Input from Independent Experts. The emergency use authorization allows the Moderna COVID-19 Vaccine to be distributed in the U.S. SILVER SPRING, Md. , 18, 2020 /PRNewswire/ — Today, the U.S.

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Drug Discovery World

JULY 26, 2022

Pharmaceutical company BioNTech will deliver the 2022 César Milstein Lecture on 26 July with a focus on how messenger RNA (mRNA) technology can be used within vaccines for cancer and Covid-19. . The first half of the lecture, titled ‘mRNA Cancer Vaccines’ will be delivered by U?ur The lecture will be delivered in two halves by U?ur

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The Pharma Data

OCTOBER 20, 2020

$1 million in research funding to support PD GENEration, a first-of-its-kind national study offering free genetic testing and counseling for people with Parkinson’s disease (PD). 10-15% of people with Parkinson’s disease have a genetic form of the disease. CAMBRIDGE, Mass.

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STAT News

OCTOBER 5, 2022

Scientists rely on gene synthesis technologies as a research tool for everything from basic research to vaccine development and drug target identification. Ever since the inception of gene synthesis, there have been concerns about possible misuse of synthetic genes.

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The Pharma Data

DECEMBER 21, 2020

military scientists to determine if it might be resistant to vaccines. The team at the Walter Reed Army Institute of Research is checking genetic sequences of the mutated virus variant posted online by British researchers, CNN reported. MONDAY, Dec.

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pharmaphorum

FEBRUARY 18, 2021

The South African coronavirus variant may cut the effectiveness of Pfizer/BioNTech’s vaccine by around two thirds, according to a laboratory study. In a response statement Pfizer and BioNTech noted that the COVID-19 vaccine did still provide protection in the lab study.

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The Pharma Data

OCTOBER 27, 2021

Appointment further strengthens Board scientific capabilities, including in genetics which is central to GSK’s R&D approach. Dietz MD, Professor of Genetic Medicine at The Johns Hopkins University School of Medicine in the United States, will join the Board of the Company as a Non-Executive Director. Dr Hal Dietz is Victor A.

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