pharmaphorum

AUGUST 4, 2022

Unlocking the secrets of the human genome has long been an ambitious pursuit for researchers around the world. Today, the landscape of genomic testing and research is rapidly progressing, with significant scientific and technological advances driving a paradigm shift in the understanding of oncology at a molecular level.

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Genome Genomics Genome Project DNA 52

Scienmag

NOVEMBER 25, 2020

Credit: University of Adelaide An international research collaboration, including scientists from the University of Adelaide’s Waite Research Institute, has unlocked new genetic variation in wheat and barley – a major boost for the global effort in breeding higher-yielding wheat and barley varieties.

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STAT News

AUGUST 17, 2022

When the Smithsonian National Museum of Natural History opened its genomics exhibit in 2013, the field was just celebrating the 10th anniversary of the completed Human Genome Project. Sequencing that first genome cost over $500 million. The genomes since cost $10,000.

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Pharmaceutical Technology

JUNE 30, 2022

Earlier this month, scientists from Cambridge University and the Madrid-based National Cancer Research Center described a novel framework tracking chromosomal instability and copy number changes in particularly deadly cancers. Genomic research have greatly expanded our understanding of disease pathophysiology over the years.

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pharmaphorum

JANUARY 24, 2023

One of the reasons is because researchers now have far more genetic data to work with than was ever previously possible. The cost of testing per human genome in 2006 was approximately $14 million , and in less than two decades, an average consumer-purchased genetic test costs $100.

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pharmaphorum

MARCH 23, 2022

With initiatives like The 100,000 Genome Project, the UK has led the world on genomic research. Representatives from industry associations and the governments and NHS in all four UK nations will meet to discuss the future of the country’s genomics sector. Plans for a joint workshop.

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pharmaphorum

JUNE 13, 2022

Canary Wharf’s bid to become a new hub for the life sciences sector in the UK has been given a boost following the decision by Genomics England to relocate to the development.

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Genome Genomics Life Science Genome Project 109

pharmaphorum

MARCH 25, 2021

The COSMIC (Catalogue of Somatic Mutations in Cancer) database, operated by the Wellcome Sanger Institute, grew out of the work of the Cancer Genome Project and has been gathering data on mutations associated with specific cancers for almost 17 years.

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Drug Discovery World

NOVEMBER 7, 2022

One might argue that this all started getting exciting with the launch of the Human Genome Project, which the National Human Genome Research Institute consider to be one of the greatest scientific feats in history 1. With Revio, researchers will be able to access that same great chemistry, but at a much larger scale.” .

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Drug Discovery World

NOVEMBER 7, 2022

A new study led by Medical Research Council-funded researchers from UCL has found that tailoring the analysis of whole genome sequencing to individual patients could double the diagnostic rates of rare diseases. . Context . The study . This personalised approach increased the diagnostic rate from 16.7% of patients. .

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Drug Discovery World

MARCH 13, 2024

Thanks to significant investment by the government into research and development, Singapore has become a leading centre for biomedical sciences in Asia. Leading the way in academic research One of Singapore’s key strengths is education and its academic prowess, particularly in cancer research.

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The Pharma Data

MARCH 1, 2022

The leading research-driven biopharmaceutical company Boehringer Ingelheim and precision medicine software company Lifebit Biotech, Ltd. Another key benefit of Lifebit’s CloudOS will be the provision of powerful analytic capabilities and global biobank connections to build a secure “dataland” for analytics and research.

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Drug Discovery World

APRIL 17, 2023

Genetic ancestry was estimated using reference populations from the 1000 Genomes Project. Tumours were sequenced using MSK-IMPACT, a gene sequencing panel that looks for mutations in up to 505 genes. The African ancestry group had a median overall survival of 45.7 months from time of diagnosis compared with 67.1

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Pharmaceutical Technology

JUNE 14, 2023

All that DNA is organised into hereditary units called genes, with humans having about 25,000 genes collectively known as the genome. The Human Genome Project Launched in October 1990, The Human Genome Project sought to sequence the entire human genome using a method called Sanger sequencing.

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Drug Discovery World

SEPTEMBER 20, 2022

To develop safe and effective gene therapies, researchers need confidence that genomic data is both complete and accurate. This considerable magnitude of difference in read length affords researchers a more complete and accurate view of genomic variation.

Gene Therapy 52

Gene Therapy Gene Genome Genomics 52

pharmaphorum

FEBRUARY 26, 2021

Here are the challenges that the medical community faces, most of which relate to the lack of research data, high cost of developing treatments or orphan drugs and greater chances of failure. . Therefore, both these factors impede the research and development teams’ process of fostering innovations in the rare disease domain.

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pharmaphorum

DECEMBER 6, 2022

Ben Hargreaves examines why a research project in the UK could provide key insights to develop treatments against many of the most prominent diseases impacting society. In 2018, the 100,000 Genomes Project completed its collection of data from 100,000 participants and the study of that collected information is still on-going.

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Genome Project Research Genome Genomics 98

Drug Discovery World

OCTOBER 16, 2023

Here, DDW’s Megan Thomas highlights the research taking place and where this is happening. This environment of research excellence, in turn, fosters R&D, innovation, spin-offs, start-ups, networking, collaboration and entrepreneurship, which sets a sturdy foundation that attracts funding, and creates an appealing work culture.

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Drug Discovery World

AUGUST 16, 2023

Decoding ‘junk DNA’ The Human Genome Project and subsequent studies discovered that most of our DNA (approximately 98%) does not actually code for proteins, with humans having approximately 20,000 tox 25,000 protein-coding genes.

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pharmaphorum

FEBRUARY 25, 2021

In the future, Gourgeon went on, the data will help NHS Scotland to understand the impact of antenatal screening and to better support research. The Scottish Government has supported the transition of genomic testing for inherited rare disease from the research setting into routine care,” she went on. “As

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pharmaphorum

SEPTEMBER 9, 2020

Everything the 100,000 Genomes Project does has to be rubber-stamped by the patients”. Unfortunately, nothing was found in the DDD study, so Charlie’s daughter was also enrolled into the UK 100,000 Genomes Project (GP), which is using whole genome sequencing as a way to diagnose and understand rare genetic diseases.

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Genome Genomics Genetics Genome Project 101

XTalks

APRIL 5, 2021

Bioinformaticians use a combination of mathematics, computer science and biology to help scientists make sense of the data gathered from research projects. The Human Genome Project could not have succeeded without the use of bioinformatics. This job furthers the field of biomedical research and supports drug development.

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Bioinformatics Engineer Scientist Genome 59

pharmaphorum

SEPTEMBER 9, 2020

Everything the 100,000 Genomes Project does has to be rubber-stamped by the patients”. Unfortunately, nothing was found in the DDD study, so Charlie’s daughter was also enrolled into the UK 100,000 Genomes Project (GP), which is using whole genome sequencing as a way to diagnose and understand rare genetic diseases.

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Genome Genomics Genetics Genome Project 79

pharmaphorum

SEPTEMBER 13, 2022

In fact, according to Blood Cancer UK research, more than half of UK adults cannot name a single symptom of blood cancer. . Over the past two centuries, researchers have identified more than 100 different types of blood cancer, while most patients may be familiar with the big three (leukaemia, lymphoma, and melanoma).

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Genome Project Genome Genomics DNA 98

Drug Discovery World

APRIL 4, 2024

“The 10,000 long-read whole genomes will bring a new dimension of insight into the genetics of the Estonian population and push us closer to the Biobank’s goal of realising health benefits for people locally and internationally.

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Biobanking Genome Genomics Genome Project 52

Pharmaceutical Technology

SEPTEMBER 15, 2022

From the Human Genome Project to contemporary drug development, collaboration is critical to the life sciences. Take Charleston, South Carolina, for example, where a growing number of medical device and pharmaceutical manufacturers, research laboratories and service companies have sprung up or settled in recent years.

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Roots Analysis

AUGUST 31, 2023

Recent advances in DNA sequencing technologies have led to significant developments in healthcare-focused research on precision medicine and diagnostics. Nutrigenomics is the science studying the relationship between human genome, nutrition and health. Figure below presents steps of direct-to-consumer nutrigenomic testing.

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Drug Discovery World

JULY 19, 2023

Evan Floden , CEO of Seqera Labs examines how data sharing platforms are impacting cancer and genomics research. Increasingly, major collaborative life sciences projects, like the Human Genome Project or Human Cell Atlas, are driving advancements and organisations – both public and private – are taking note.

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Genome Genomics Bioinformatics Genetics 52

pharmaphorum

APRIL 20, 2022

As is typical, the research built on work going back years prior, specifically to 1987 when the first CRISPR mechanism was identified in E. coli, and their research in turn formed the foundation for the CRISPR-based therapies being explored to create new treatment options. Why cancer? The pipeline.

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Gene Editing DNA Gene Genetics 52

Roots Analysis

AUGUST 28, 2022

Currently, several stakeholders are engaged in offering integrated solutions (platforms, software applications, services) to perform tissue analysis and spatial phenotyping, across the full continuum from discovery through translational and clinical research. 70+ spatial Genomics solutions are developed by industry and non-industry players.

Genome 52

Genome Genomics RNA Genome Project 52

XTalks

FEBRUARY 11, 2021

The Human Genome Project recently marked 20 years since the publication of the first full sets of human genomic sequences, an endeavor that spanned well over a decade. Today, new next-generation sequencing technologies allow for the sequencing of complex genomes within just a day or two.

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Genetics DNA Genome Genomics 119

Drug Discovery World

MARCH 6, 2024

Guiding neurological drug discovery and development to success The 20 years since the Human Genome Project has seen transformational advances in the molecular understanding of cancers and rare genetic diseases, leading to genetically informed, personalised selection of therapies and massively improved outcomes for many patients.

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pharmaphorum

SEPTEMBER 14, 2020

Here he gives us a deeper look at how genomic medicine is evolving and the barriers that are preventing it from reaching its full potential. It’s likely to contain what we call ‘control regions’ – parts of the genome that control whether a gene is turned on or off. It’s still difficult to interpret a lot of these results.

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Genome Genomics Medicine Gene 117

The Pharma Data

APRIL 6, 2021

Bayer will present new research across its oncology portfolio at the virtual American Association for Cancer Research (AACR) Annual Meeting 2021 , taking place over two weeks on April 10-15 and May 17-21, 2021. Overall, these data stress Bayer’s commitment to continued research in some of the company’s key areas of focus in oncology.

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Drug Discovery World

JULY 15, 2022

The first complete, gapless sequence of a human genome was published 1 April 2022 in a special issue of the journal Science 1. While The Human Genome Project mapped about 92% of the human genome two decades ago, sequencing the last 8% of the genome proved highly challenging.

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