Drug Discovery World

JANUARY 26, 2024

Delegates will hear how the integration of AI with cutting-edge technologies like patient-on-a-chip, real-time nano-sensing and stem cell genomic diversity is addressing the critical challenge of predicting drug behaviour in humans.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Genome 52

pharmaphorum

MARCH 19, 2021

The oceans of health data out there can be overwhelming for pharma companies to manage – but if extracted correctly, the prospect to develop drugs from scratch in as little as a year is very real, says Lifebit CEO, Dr Maria Chatzou Dunford. . on Big data: astronomical or genomical? ,

Bioinformatics 59

Bioinformatics Drugs Genome Genomics 59

pharmaphorum

OCTOBER 12, 2022

Those will be combined with AZ’s analysis framework for rare variant genomic discoveries, as well as the drugmaker’s own AI tools, including JARVIS – a tool which focuses on non-coding or ‘junk’ regions of the genome.

Genome 64

Genome Genomics DNA Drugs 64

Pharmaceutical Technology

NOVEMBER 7, 2022

Out of the total job titles, the top five roles commanded a 95.48% share in the overall IT recruitment activity of the UK’s pharma industry in October 2022. Top five pharma companies in the UK’s IT recruitment activity in October 2022. Junior Level job postings dominate in October 2022.

Genome 130

Genome Genomics Pharma Companies Development 130

pharmaphorum

OCTOBER 13, 2020

In an interview with pharmaphorum Mortazavi said that the technology will work in concert with the network biology and genomics expertise already present within the company. He said: “These big pharma companies have every type of technology available to them.

Gene Silencing 94

Gene Silencing Gene RNA Genome 94

pharmaphorum

OCTOBER 18, 2022

US-based Tempus has built a precision medicine platform – powered by artificial intelligence and machine learning – that sifts through a large library of anonymised patient data, including results of clinical, molecular, and genomic testing.

Production 52

Production Clinical Trials Clinical Trials Genome 52

pharmaphorum

JULY 8, 2022

The aim is to overcome a very low success rate in drug discovery, with just 10% of candidates making it into clinical development despite the application of new computational technology techniques to handle an ever-growing amount of biomedical data, for example from genomics studies. billion, according to the report.

Drugs 130

Drugs Clinical Development Marketing Genome 130

pharmaphorum

NOVEMBER 27, 2022

A group representing pharma companies selling precision therapies for cancer has called for a change to the way genomic testing is done in Scotland, to make sure patients get access to targeted drugs. The post Genomic testing ‘should be offered to all cancer patients in Scotland’ appeared first on.

Genome 93

Genome Genomics Genetics Medicine 93

pharmaphorum

OCTOBER 20, 2021

The trial – which will be supported by pharma company Eisai and Ionian University in the US – will see if the test can identify people who have mild cognitive impairment (MCI) due to Alzheimer’s disease. ” The post Eisai-backed trial will assess Altoida’s digital test for early Alzheimer’s appeared first on.

Trials 78

Trials Genome Genomics Bioinformatics 78

pharmaphorum

JANUARY 24, 2023

The cost of testing per human genome in 2006 was approximately $14 million , and in less than two decades, an average consumer-purchased genetic test costs $100. The same is becoming true for the healthcare industry, and one of the first major breakthroughs in the area was the 100,000 Genomes Project.

Genetics 92

Genetics Drugs Genome Project Biobanking 92

Drug Discovery World

MAY 22, 2023

Cell therapy, RNA technology, antibody drug conjugates and AI/machine learning are among the key areas of investment for pharma, according to a new report. Clarivate’s ‘Biopharma Dealmaking in 2023’ report examines how pharma companies are replenishing their pipelines as many face a steep patent cliff.

RNA 52

RNA Pharma Companies Antibody Life Science 52

pharmaphorum

NOVEMBER 19, 2020

The latest crop of recipients in the G4A scheme were selected from more than 400 applications from companies in dozens of countries around the world and have apps covering women’s health, chronic conditions, genomic testing, disease management and telemedicine.

Genome 64

Genome Genomics Nurses Pharma Companies 64

Drug Discovery World

OCTOBER 16, 2023

Despite the overall reduction in major pharma R&D centres in the UK, global pharma companies continue to engage with academic and biotech organisations here, particularly in hotspots such as the Golden Triangle, the Northwest, and Scotland, through the strong networks that have been developed between these organisations.

Drugs 75

Drugs Life Science Gene Therapy Genome 75

pharmaphorum

JANUARY 24, 2022

” Watson Health offers a range of other services of course, including tools for genomic analysis and running clinical trials that have found favour with a number of pharma companies.

Radiology 111

Radiology Marketing Genome Genomics 111

XTalks

DECEMBER 20, 2023

In 2024, pharma companies and emerging biotechs will improve candidate safety profiles and reduce off-target effects by exploiting predictive intelligence unlocked by AI,” she predicts. These companies are at various stages of research and clinical trials.

Life Science 119

Life Science Gene Editing Development Clinical Trials 119

Drug Discovery World

FEBRUARY 6, 2024

Biopharma and biotech companies without these capabilities are keen to harness these technologies and the number of strategic partnerships with such companies is accelerating at an unprecedented rate. Automation is also being applied to genomics sample preparation, an area that requires particular robustness and scalability.

Marketing 69

Marketing Medicine Genome Genomics 69

pharmaphorum

DECEMBER 9, 2022

The PharmaStars accelerator was set up last year to help bridge the gap between digital health start-ups and potential pharma partners, which can be instrumental in making sure their technologies meet their potential – and help them to navigate the challenges of developing them in the highly regulated healthcare environment.

Life Science 52

Life Science DNA Genome Genomics 52

pharmaphorum

APRIL 19, 2021

But it has also faced criticism from pharma companies that say it undervalues medicines – patients in the country were denied access to the expensive cystic fibrosis drug Orkambi for four years because of a pricing row with NICE and the NHS.

Medicine 77

Medicine Pharma Companies Genome Genomics 77

Drug Discovery World

JANUARY 21, 2024

He has founded and led three bio-AI technology companies, each of which led revolutions in medicine, genomics, agriculture, and conservation. Is pharma’s commercial model dying?

Protein 52

Protein Vaccination Vaccine Development 52

Drug Discovery World

JULY 19, 2023

Evan Floden , CEO of Seqera Labs examines how data sharing platforms are impacting cancer and genomics research. Increasingly, major collaborative life sciences projects, like the Human Genome Project or Human Cell Atlas, are driving advancements and organisations – both public and private – are taking note.

Genome 52

Genome Genomics Bioinformatics Genetics 52

Drug Discovery World

MAY 6, 2024

As companies move through the phases of development, they benefit from a long-established ecosystem of competency in clinical regulation. So, in this way there is a cross fertilisation from the bigger companies to newer ones. This knowledge base will accelerate the sector and encourage new companies.

Drugs 59

Drugs Life Science Gene Editing Gene 59

pharmaphorum

APRIL 7, 2022

” Now, the aim is to layer in genomics surveillance using Ares’ next-generation sequencing (NGS) expertise, improving the monitoring of resistant pathogens and making sure that antibiotics are prescribed wisely. “AMR, which is now estimated to directly account for nearly 1.3

Bioinformatics 52

Bioinformatics Genetics Genome Genomics 52

Camargo

NOVEMBER 11, 2020

In November 2017, Foundation Medicine received approval for FoundationOne CDx , a genomic profiling test for solid state tumors, which paved the way for partnerships with pharma companies’ therapeutics. Approval of the Month: Companion Diagnostic for Bayer’s Vitrakvi Should Lead to Improved Patient Outcomes.

Development 242

Development Bioequivalency Generic Drugs Production 242

pharmaphorum

OCTOBER 28, 2020

That narrative, for many patients, is that pharma companies just don’t care”. Pharma is swimming against the tide and can’t pretend that the democratisation of medicines data doesn’t exist — because it’s already here. 72% do not feel listened to by pharmaceutical companies. Yet it is widely mistrusted.

Medicine 119

Medicine Pharma Companies Vaccination Vaccine 119

XTalks

DECEMBER 13, 2023

Now, let’s delve into the list of the top ten fastest growing biotech companies in 2023, ranked by their compound annual growth rate (CAGR). These companies were identified through The Americas’ Fastest-Growing Companies 2023 list by the Financial Times.

Genetics 111

Genetics Vaccination Vaccine DNA 111

Drug Discovery World

DECEMBER 27, 2023

In this episode, Kelland shares what she means by the ‘next pandemic’, the lessons learnt from the Covid-19 pandemic, and the role of global health organisations and pharma companies going forward. A deep dive into US drug discovery What lies in the future for genomics and big data? Listen here.

Clinical Trials 69

Clinical Trials Clinical Trials Drugs Development 69

XTalks

OCTOBER 8, 2020

A fresh or renewed start can be effectively facilitated with a corporate name change to reflect certain changes in a company’s values, missions and interests. As another recent example, genomics data company Wuxi NextCODE underwent restructuring and has emerged under the new name Genuity Science. NYSE/TSX: BHC) in 2018.

Manufacturing 98

Manufacturing Life Science Cosmetics Regulation 98

Pharmaceutical Technology

FEBRUARY 13, 2023

With the latest advances in whole genome sequencing , it is increasingly clear that rare epilepsies are largely caused by a single genomic mutation, says Ferraro. New developments in the anti-seizure pipeline Genomic screenings can also be used to sharpen the efficacy of already available treatments.

Research 264

Research Gene Gene Therapy Genome 264

pharmaphorum

SEPTEMBER 18, 2020

But although it was dubbed a “dangerous game”, some companies came out on top… On 6th April 1999, two companies with similar science-based cultures and a shared vision of the pharmaceutical industry came together to form what’s now considered as one of the top ten pharma companies in the world: AstraZeneca.

Pharma Companies 116

Pharma Companies Sales Vaccination Vaccine 116

XTalks

AUGUST 18, 2020

Instead of RNA extraction, the Yale test involves use of a reagent that when mixed with a saliva sample and heated for a short period of time, releases the viral genome for subsequent detection with PCR. This is significant because shortages of RNA extraction kits have been a recurrent issue since the beginning of the pandemic.

FDA Approval 90

FDA Approval Reagent RNA Genome 90

XTalks

AUGUST 27, 2020

The company’s lead adenoviral vector-based vaccine candidate, Ad26.COV2.S, Johnson & Johnson began work on the vaccine in January 2020, as soon as the genomic sequence for SARS-CoV-2 — the coronavirus that causes COVID-19 — was made available. S, was developed using Janssen’s proprietary AdVac technology.

Vaccination 52

Vaccination Vaccine Trials Clinical Trials 52

XTalks

OCTOBER 15, 2021

In 2013, the Lacks family came to an agreement with the National Institutes of Health (NIH) to have control over the genetic information generated when researchers sequenced the genome of the HeLa cells. However, the agreement did not include a share of any profits that researchers or pharma companies may make from use of the cells.

Vaccination 105

Vaccination Vaccine Gene Mapping Doctors 105

pharmaphorum

MARCH 28, 2022

Built under a government tender, AION Labs comprises four large international pharma companies – AstraZeneca , Merck, Pfizer , and Teva – and another core partner, the Israel Biotech Fund. The post Big pharma companies partner to form AI-based start-up appeared first on. The partnership. About the author .

Pharma Companies 98

Pharma Companies Antibody Protein Development 98

Drug Discovery World

AUGUST 8, 2023

According to a report by Deloitte, globally India is the third largest in the world by volume and 11th by value, comprising over 3,000 pharma companies and 10,500 manufacturing facilities 2. The growth and potential in Genome Valley are expressed in the continuous investment in the hub.

Research 52

Research Drugs Genome Genomics 52

Delveinsight

DECEMBER 15, 2020

Gannex Pharma has received Fast Track designation approval from FDA for its drug candidate ASC42 for non-alcoholic steatohepatitis (NASH). The FTA designation will help the pharma company to advance its research and development in the NASH landscape and help its commercialization in the market.

Vaccination 54

Vaccination Vaccine Gene Therapy Gene 54

pharmaphorum

DECEMBER 6, 2022

A few decades ago, gathering genetic data on the scale of the 100,000 Genomes Project would have been unthinkable – it was only in 2003 that the entire human genome was mapped. In 2018, the 100,000 Genomes Project completed its collection of data from 100,000 participants and the study of that collected information is still on-going.

Genome Project 95

Genome Project Research Genome Genomics 95

Drug Discovery World

JANUARY 26, 2023

As such, 2022 saw a marked fall in ROI for global pharmaceutical companies and their research and development activities. According to research from Deloitte 1 , the average ROI in R&D for global pharma companies fell to just 1.2% in 2022, a steep decline compared to the record 6.8% the industry experienced in 2021.

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