pharmaphorum

NOVEMBER 17, 2020

Researchers at the Wellcome Sanger Institute in the UK are working on software to monitor the genome of SARS-CoV-2 coronavirus in the hope of spotting changes that could affect the fight against COVID-19. Backed by £12.2

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STAT News

SEPTEMBER 30, 2022

The shortlist includes researchers who elucidated how cells make energy, those who discovered the chemical chatter of bacteria, many of the brilliant minds who shepherded us into the “ era of the genome ,” and most prominently, the pioneers behind the mRNA Covid vaccines. Read the rest…

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Bacteria Genome Genomics Vaccination 124

The Pharma Data

MAY 22, 2023

WHO launches global network to detect and prevent infectious disease threats WHO and partners are launching a global network to help protect people from infectious disease threats through the power of pathogen genomics. COVID-19 highlighted the critical role pathogen genomics plays in responding to pandemic threats.

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Genome Genomics Bioinformatics Bacteria 52

Drug Discovery World

JULY 10, 2023

If there’s one thing I would take from the Summer 2023 issue of Drug Discovery World , it would be that the application of technologies and processes throughout the pharmaceutical industry are changing how scientists pursue the development of therapies. There are myriad ways that this is being enabled.

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Gene Therapy Gene Scientist Gene Editing 52

pharmaphorum

JANUARY 6, 2023

The UK has formed an partnership with German biotech BioNTech to provide up to 10,000 patients with access to personalised cancer therapies, in another example of the country embracing the mRNA technologies that underpinned COVID-19 vaccines. It will also cover some infectious disease targets.

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Clinical Trials Clinical Trials Trials Vaccination 111

pharmaphorum

FEBRUARY 1, 2022

1 strain, and there is somewhat conflicting evidence on its ability to evade the protection from vaccines, according to new studies. That increase was seen regardless of the vaccination status of the secondary cases, and there was an increased risk of spread within vaccinated households with BA.2 The new BA.2 1 and 70% for BA.2

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Vaccination Vaccine Scientist Genome 98

Scienmag

JANUARY 24, 2021

A group of scientists is calling on governments to consider the continued use of strict control measures as the only way to reduce the evolution and spread of new COVID-19 variants.

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Genome Genomics Scientist Vaccination 74

Drug Discovery World

NOVEMBER 8, 2022

Mutations have enabled the virus to grow stronger and smarter, evading antiviral drugs and vaccines. . The monkeypox virus is very similar to the vaccinia virus, which has been used as a vaccine to treat smallpox. Monkeypox has infected more than 77,000 people in more than 100 countries worldwide.

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Drugs DNA Vaccination Vaccine 52

Scienmag

SEPTEMBER 30, 2020

Scientists are fighting back with multiple strategies, including vaccines, repurposed drugs developed for other diseases and brand-new therapies. Now, researchers reporting in ACS Central Science have identified small molecules that target a structure within the RNA genome […].

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RNA Genome Genomics Branding 40

The Pharma Data

DECEMBER 28, 2020

Testing Therapies, Antivirals and Vaccines. The Nanovaccine Institute at Iowa State University (ISU) is using nanotechnology to develop a vaccine will be able to be administered without needles and in one dose. Health Canada granted authorization to the Moderna COVID-19 vaccine on December 23. Other Industry News.

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Genome Genomics Vaccination Vaccine 52

The Pharma Data

JANUARY 11, 2021

health officials raced to ramp up the delivery of COVID-19 vaccines across the country as both coronavirus case counts and death tallies continued to hit record highs. “We really need to get this vaccine out more quickly, because this is really our only tool,” Dr. Scott Gottlieb, former commissioner of the U.S. .

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Vaccination Vaccine Nurses Genome 52

Delveinsight

DECEMBER 15, 2020

Pfizer, BioNTech COVID-19 Vaccine rolls out in a watershed moment. In a historic first, the US FDA issued an Emergency Use Authorization (EUA) to the COVID-19 mRNA, BNT162b2, vaccine candidate for COVID-19 of Pfizer-BioNTech. The vaccine is the first-ever mRNA vaccine to get to the EUA and is developed in record-time low.

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Vaccination Vaccine Gene Therapy Gene 54

pharmaphorum

DECEMBER 20, 2022

Genomic profiling has made it possible to diagnose and treat patients with far greater precision. Often, the initial focus is on participating in the data revolution by expanding genomic sequencing capacity, implementing electronic health records (EHRs), and so on.

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Genome Genomics Trials Doctors 105

The Pharma Data

JULY 6, 2021

If a virus is disease-causing, the right mutation can allow the virus to escape the immune response by changing the viral pieces the immune system uses to recognize the virus as a threat, pieces scientists call epitopes. These epitopes could then be used in a vaccine to train T cells, providing protective immunity.

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Vaccination Vaccine Research Immune Response 52

Pharmaceutical Technology

FEBRUARY 3, 2023

The field of genomic medicine has reached a true turning point. With scientists fervently developing mRNA vaccines, nucleic acid therapeutics, and viral vector-based gene therapies, clinicians are set to have a growing number of tools available to treat a wide range of conditions, from infectious diseases to genetic disorders and more.

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Genome Genomics Medicine Gene Therapy 244

Delveinsight

AUGUST 27, 2020

Moderna’s COVID-19 vaccine triggers an immune response in older adults. Moderna showed robust phase 1 results for its COVID-19 vaccine in adults up to 55 last month. It is now following up with data from a small group of older adults, and they look positive. Targeted drug combo attacks breast cancer brain metastases in mice.

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Vaccination Vaccine Research Trials 53

XTalks

OCTOBER 21, 2020

The answer may lie in the genetic code of the virus, which scientists at Duke University have found contains several silent mutations that affect protein folding. At best, it is slowly mutating, which is good news for vaccine developers as they don’t have to contend with potentially multiple strains of the virus.

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RNA Protein Genome Genomics 98

pharmaphorum

JANUARY 20, 2021

UK biotech ConserV Bioscience has joined with California’s Lawrence Livermore National Laboratory to develop broad-spectrum coronavirus vaccines as concerns mount over potentially more infectious strains emerging in the UK, South Africa and Brazil.

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Vaccination Vaccine Protein RNA 52

pharmaphorum

JANUARY 24, 2022

Some scientists have given it the nickname ‘stealth variant’, because it is more difficult to detect than BA.1 “Our continued genomic surveillance allows us to detect them and assess whether they are significant,” she added. 2, the sub-variant of Omicron (BA.1) 2 causes more severe illness than Omicron BA.1,

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Vaccination Vaccine Genome Genomics 98

The Pharma Data

AUGUST 24, 2020

Hong Kong scientists are reporting the case of a healthy man in his 30s who became reinfected with coronavirus four and a half months after his first bout. They say genome sequencing shows the two strains of the virus are “clearly different”, making it the world’s first proven case of reinfection. Image copyright.

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Immune Response Genome Project Genome Genomics 52

Drug Discovery World

DECEMBER 12, 2022

Other research updates include a study by NIH 5 researchers using post-mortem brain tissues to understand genomic differences in individuals with attention deficit hyperactivity disorder. The study advances our understanding of ADHD by showing how the condition is tied to changes in how certain genes are expressed in the brain. Analysis .

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Drugs Gene Editing Genome Genomics 52

Pharmaceutical Technology

JUNE 30, 2022

Earlier this month, scientists from Cambridge University and the Madrid-based National Cancer Research Center described a novel framework tracking chromosomal instability and copy number changes in particularly deadly cancers. Genomic research have greatly expanded our understanding of disease pathophysiology over the years.

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Genome Project Genome Genomics DNA 130

XTalks

MARCH 8, 2022

From leading COVID-19 vaccine developments to being at the helm of the latest gene therapies and inventing ground-breaking DNA technologies like CRISPR, women have been at the forefront of some of the most leading-edge scientific discoveries in recent years, both as innovators and leaders.

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Life Science Gene Therapy DNA Vaccination 105

Drug Discovery World

SEPTEMBER 26, 2023

Molnupiravir induces mutations in the virus’s genome during replication, with the aim of damaging or killing the virus. Researchers have uncovered a link between antiviral drug molnupiravir and a pattern of mutations in the SARS-CoV-2 virus.

Genome 52

Genome Genomics Research Clinical Trials 52

Sciensano

AUGUST 22, 2022

Event type: symposium Audience: policy makers scientists university staff Description: Through this new Symposium “Health challenges of the 21st century”, Sciensano aims to highlight different areas of its research, and encourage you to interact with us. The themes selected for this first edition are: Crisis preparedness/Innovation.

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Genome Genomics Scientist Vaccination 80

Drug Discovery World

JULY 3, 2023

The international study into the pandemic potential of avian flu, which is led by scientists at the MRC-University of Glasgow Centre for Virus Research (CVR), identified the human gene BTN3A3, which is commonly expressed in our airways, as a key human defence against avian flu.

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Gene Genetics Scientist Research 52

The Pharma Data

JANUARY 8, 2021

announced Thursday that early testing shows its vaccine does still work against the more infectious variants of SARS-CoV-2 first found in Britain and South Africa, Reuters reported. vaccine rollout plagued by delays, Dr. Anthony Fauci urged Americans to be patient on Thursday. There was a glimmer of good news, however: Pfizer Inc.

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Vaccination Vaccine Scientist Genome 52

Drug Discovery World

MAY 6, 2024

Cell and gene therapy is a particular area of focus for the region, centred around the VU LSC-EMBL Partnership for Genome Editing Technologies, a partnership between the Vilnius University Life Sciences Center (VU LSC) and the European Molecular Biology Laboratory (EMBL).

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Drugs Life Science Gene Editing Gene 59

Drug Discovery World

JULY 19, 2023

Evan Floden , CEO of Seqera Labs examines how data sharing platforms are impacting cancer and genomics research. Increasingly, major collaborative life sciences projects, like the Human Genome Project or Human Cell Atlas, are driving advancements and organisations – both public and private – are taking note.

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Genome Genomics Bioinformatics Genetics 52

The Pharma Data

NOVEMBER 26, 2021

To accelerate medical exploration with AI in a sequestration- conserving way, Owkin has assembled a global exploration network powered by allied literacy, which allows data scientists to securely connect to decentralized,multi-party data sets and train AI models without having to pool data. Co-Founder and CEO at Owkin. “

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Development Scientist Medicine Drugs 52

The Pharma Data

NOVEMBER 18, 2021

To accelerate medical exploration with AI in a sequestration- conserving way, Owkin has assembled a global exploration network powered by allied literacy, which allows data scientists to securely connect to decentralized,multi-party data sets and train AI models without having to pool data. Co-Founder and CEO at Owkin. “

Development 52

Development Scientist Medicine Drugs 52

The Pharma Data

FEBRUARY 25, 2022

Several FDA-approved drugs – including for type 2 diabetes, hepatitis C and HIV – significantly reduce the ability of the Delta variant of SARS-CoV-2 to replicate in human cells, according to new research led by scientists at Penn State. ” The findings published today (Feb. 25) in the journal Communications Biology. .

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pharmaphorum

JULY 7, 2021

The Oxford-AstraZeneca vaccine is the most potent symbol not just of UK achievement but of collaboration across the sector. We need to recover the UK’s performance post-pandemic and today’s Vision sets out plans to make that happen with more integration of genomics, clinical research and health data.

Life Science 59

Life Science Manufacturing Genome Genomics 59

XTalks

FEBRUARY 26, 2021

He worked with renowned fungal scientist (mycologist) L.H. However, when a strain of HeLa cells was sequenced and researchers published its genome in 2013, Skloot informed the Lacks family about this. And at the forefront of Moderna’s COVID-19 vaccine development was Black immunologist Dr. Kizzmekia Corbett.

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Scientist Research Genetics Cosmetics 69

The Pharma Data

MARCH 16, 2021

Accurate detection and differentiation of SARS-CoV-2 mutations can help assess the spread of circulating variants and monitor their potential impact on therapeutics, vaccines and public health interventions. 1 lineage gained prominence in late 2020, with each carrying a number of genomic mutations. Variants of B.1.1.7, 1.351 and P.1

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Antibody Clinical Trials Clinical Trials Vaccination 52

Drug Discovery World

APRIL 30, 2024

The biggest growth driver for mRNA therapeutics came from the Covid-19 pandemic, when mRNA-based vaccines proved effective in treating SARS-CoV-2, and pharmaceutical companies such as Pfizer/BioNTech and Moderna were successful in bringing these treatments to market. mRNA is a molecule made up of a single strand of ribonucleic acid (RNA).

RNA 52

RNA Protein Vaccination Vaccine 52

Drug Discovery World

OCTOBER 4, 2022

Automated systems have become a prominent feature throughout drug discovery, helping scientists save time and assisting in reproducible experiments for more verifiable results. Automation. As a crucial stage in drug discovery, it’s no surprise that activity in screening, whether it be technology or services, is constant.

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Gene Therapy Drugs Gene Manufacturing 52