XTalks

JANUARY 17, 2024

To gain insights into how clinical trials for lupus can be enhanced with RWD sources, we spoke with Frederico Calado, VP of Global Real-World Solutions at Alira Health , and Dr. Kaleb Michaud, Professor, Division of Rheumatology, University of Nebraska Medical Center. Kaleb Michaud: In developing lupus solutions, RWD plays a crucial role.

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Clinical Trials Clinical Trials Trials Life Science 52

Drug Discovery World

MARCH 30, 2023

Likang Life Sciences has been granted implied approval by China’s National Medical Products Administration (NMPA) for the clinical trial of its innovative personalised neoantigen-targeted vaccine LK101 Injection for advanced solid tumours. Hence, there is a need to increase clinical investigations in this promising area.”

Regulation 52

Regulation Vaccination Vaccine Trials 52

Drug Discovery World

MAY 6, 2024

Thanks to a prestigious academic legacy, Europe has long been a dominant region for life sciences. Europe is traditionally a life sciences powerhouse, with a strong tradition in pharmaceutical discovery. The oldest, still active pharmaceutical company worldwide, Merck, started life in 1668 in Darmstadt, Germany.

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Drugs Life Science Gene Editing Gene 59

The Pharma Data

JANUARY 26, 2021

offered its genomics expertise to identify emerging variants of the SARS-CoV-2 virus to countries that lack the resources to make such identifications. has carried out more than half of all SARS-CoV-2 genome sequences submitted to the global database. On Tuesday, the U.K. The offer came as part of the U.K.’s South Africa and Brazil.

Genome 52

Genome Genomics Vaccination Vaccine 52

XTalks

OCTOBER 20, 2023

Clinical-stage genome editing company Intellia Therapeutics has received clearance from the US Food and Drug Administration (FDA) for its Investigational New Drug (IND) application to start a pivotal phase III trial of NTLA-2001 for the treatment of transthyretin (ATTR) amyloidosis with cardiomyopathy.

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In-Vivo Gene Editing Trials Gene 52

Drug Discovery World

MARCH 13, 2024

With government support and strong academic institutions, does Singapore have what it takes to become a global centre for life sciences? DDW’s Diana Spencer explores how the country is turning pioneering science into a successful biotech industry.

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Life Science Genome Genomics Research 69

XTalks

DECEMBER 20, 2023

As we step into 2024, the life sciences continue to evolve at an unprecedented pace, driven by technological innovation, a deeper understanding of human biology and the application of new technologies in areas like drug development and health wearables. These companies are at various stages of research and clinical trials.

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Life Science Gene Editing Development Clinical Trials 119

XTalks

APRIL 24, 2023

Rare disease clinical trials are complex due to the additional scientific, medical, operational and regulatory requirements of newly emerging advanced therapies, such as gene therapy,” says Dr. Terence Eagleton, MB BS, Senior Medical Director at the global clinical research organization (CRO) Medpace. Reference: Chung DC, et al.

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Gene Therapy Gene Trials Clinical Trials 95

XTalks

SEPTEMBER 12, 2023

Life science podcasts have emerged as an invaluable tool for building connections with audiences in the digital era. Furthermore, we’ll explore the unique advertising opportunities that this platform offers, positioning brands at the forefront of the life science industry. The result?

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XTalks

NOVEMBER 7, 2022

These tumor-derived entities are used to derive genomic and proteomic data. Gleich, MD, FACS, Senior Vice President, Medical Department, and Dr. Christopher Huth, PhD, Senior Clinical Trial Manager, Clinical Trial Management. Liquid Biopsy Use in Oncology Clinical Trials.

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Clinical Trials Clinical Trials Trials FDA Approval 98

Crucial Data Soutions

AUGUST 6, 2020

In this blog post, we recap the top three tips our panelists provided throughout the presentation to confront the hurdles in today’s clinical trial landscape and achieve efficient study execution. For a number of years, the clinical trials industry relied on case report forms (CRFs) and a select few non-CRF sources (i.e.,

Clinical Trials 72

Clinical Trials Clinical Trials Trials Genome 72

pharmaphorum

JULY 5, 2022

I recently had the pleasure of attending the PING Conference 2022 , which had the tagline of ‘The Golden Age for Life Sciences Innovation’. Aspirations for the UK in life sciences. So, with all that said, are we really in a golden age for UK life sciences? Reducing complexity across the NHS.

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Life Science Biobanking Medicine Marketing 98

Drug Discovery World

JANUARY 9, 2023

It is hoped that a new partnership between the UK government and BioNTech will help accelerate clinical trials of personalised immunotherapies for cancer and infectious disease vaccines. . The agreement means cancer patients will get early access to trials exploring personalised mRNA therapies, like cancer vaccines. .

Research 52

Research Vaccination Vaccine Trials 52

Drug Discovery World

OCTOBER 16, 2023

Maina Bhaman, Partner at Sofinnova Partners, says: “The UK is an attractive space for drug discovery companies and a prime environment for investment due to its talent, infrastructure, and genomics research. CellProthera also appointed the Newcastle Centre for Life’s GMP cell therapy centre to produce the ATMP.”

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Drugs Life Science Gene Therapy Genome 75

XTalks

MARCH 28, 2024

Building Cancer Awareness and Empowering Métis Youth: Featuring Jordyn Playne, President, Métis Nation of Ontario Youth Council – Xtalks Life Science Podcast Ep. Early clinical trials have shown promising results and this therapy could become a valuable addition towards CRC treatment in the future.

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Gene Editing Life Science Clinical Trials Clinical Trials 59

The Pharma Data

SEPTEMBER 28, 2020

Accenture Applied Intelligence announced a new data and analytics approach to manage and derive insights from paediatric acute myeloid leukaemia (AML) genomic data, with the potential to improve precision medicine. Insights from project could potentially improve precision medicine use for paediatric AML.

Genome 52

Genome Genomics Clinical Trials Clinical Trials 52

Drug Discovery World

MAY 11, 2023

Fundraising and investment are a core pillar of not just BioTrinity events but of the drug discovery industry at large, so events such as Tuesday’s keynote, Investment Trends for the Life Sciences Industry, are critical for members of the industry.

Life Science 52

Life Science Genetics Vaccination Vaccine 52

Drug Discovery World

NOVEMBER 1, 2022

The Sector Snapshot 2022 was commissioned by AusBiotech, an Australian industry body representing and advocating for organisations doing business in and with the global life sciences economy 1. Another key figure outlined by AusBiotech is that Victoria and New South Wales are home to 73% of the life science sector.

Drugs 52

Drugs Life Science Research Genome 52

The Pharma Data

OCTOBER 19, 2020

20, 2020 /PRNewswire/ — Caris Life Sciences® , a leading innovator in molecular science focused on fulfilling the promise of precision medicine, announced today that Winship Cancer Institute of Emory University (Winship) has joined Caris’ Precision Oncology Alliance (The Alliance/POA). Winship is one of 32 U.S.

Life Science 52

Life Science Clinical Trials Clinical Trials RNA 52

XTalks

MARCH 25, 2021

Xtalks is proud to announce the launch of the Xtalks Life Science podcast. Subscribe to the Xtalks Life Science Podcast to never miss a new episode. Fresh Conversations About Life Science Topics. Sarah is passionate about science communication and journalistic integrity.

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XTalks

NOVEMBER 30, 2023

The safety and efficacy of Cabenuva were established through two randomized, open-label, controlled clinical trials involving 1,182 HIV-infected adults who were virologically suppressed (HIV-1 RNA less than 50 copies/mL) before initiating Cabenuva treatment. The Phase I trial for HB-500 is scheduled to start in the first half of 2024.

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FDA Approval Gene Therapy Clinical Trials Clinical Trials 111

Drug Discovery World

JULY 11, 2023

Tim Lowery , President, JSR Life Sciences, asks whether artificial intelligence can do for life sciences what it has done in other sectors and whether these tools can keep up with the complexities of human biology. So, where do we go from here to realise their potential in life sciences?

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Big Data Development Life Science Drugs 40

pharmaphorum

AUGUST 11, 2022

There have been great strides made in genomics to refine tools that determine the safest, most effective course of treatments for patients across a number of disease states. Looking at an individual’s genomic profile also provides an understanding of appropriate medication dosage.

Genome 98

Genome Genomics Genetics Drugs 98

Drug Discovery World

FEBRUARY 29, 2024

Most new drugs fail during human trials, which is expensive and wasteful: 80% of drug R&D spend is consumed in these failures, and 80% of this is due to efficacy and safety, so predicting this is very important and valuable. MT: What are the primary challenges associated with human-centric data and how do you overcome these?

Drugs 59

Drugs Genome Genomics Genetics 59

XTalks

APRIL 21, 2023

The application of whole genome sequencing (WGS) to derive a more complete understanding of cancer has been a central goal of cancer researchers even before the first human genome was decoded in 2003. Ultima Genomics has already partnered with other leading biotech startups.

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Genome Genomics Bioinformatics Genetics 97

XTalks

JANUARY 2, 2024

XTALKS WEBINAR: Strategic Design Decisions in Rare Disease Trials Live and On-Demand: Thursday, February 8, 2024, at 11 am EST (4 pm GMT/UK) Register for this free webinar to discover invaluable strategies to effectively navigate rare disease trials, enhancing endpoint adaptation, data quality and clinical interpretation.

FDA Approval 111

FDA Approval Gene Therapy Gene Trials 111

XTalks

MAY 20, 2022

Depending on the type of field or company, you can pursue clinical scientist jobs with a major in biology, medicine, medical technology, chemistry, immunology and other related life science and pre-medical degrees. Clinical Pharmaceutical Science. Genetic Science. Computer Science and Modeling. Blood transfusion.

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Scientist Life Science Clinical Research Doctors 105

Drug Discovery World

NOVEMBER 23, 2023

Narain , PhD, President and CEO of BPGbio asks how a better calibre of biobanks in life sciences can lead to more drugs making it to market. We eagerly await future data read-outs from trials because after all, it is the drug that patients are waiting for, not our fancy algorithms. But the utility of biobanks varies.

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Biobanking Drugs Medicine Genome 59

pharmaphorum

JANUARY 19, 2023

Run by Life Science Integrates, Pharma Integrates was in its 11th year in 2022. BioNTech, or Pfizer, or others – within nine months, we had a vaccine, ran clinical trials at scale, cheaply and quickly.” On the subject of cost, he continued: “So long as a phase 3 trial costs $3 billion you’re not going to run many.

Life Science 96

Life Science Vaccination Vaccine Genome 96

XTalks

NOVEMBER 3, 2023

CRISPR works as genetic scissors to edit parts of the genome. The companies used data from the 1,000 Genomes Project but from that, only 61 datasets made the cut to encompass the ideal patient population. “I In June, Vertex shared data from the ongoing long-term, Phase I/II/III open-label CLIMB-111 and CLIMB-121 trials in which 94.1

Gene Therapy 59

Gene Therapy Gene Gene Editing In-Vivo 59

pharmaphorum

SEPTEMBER 12, 2022

Alongside drugs and therapeutics, data collection and technology enhancements have redefined the traditional healthcare experience, especially within oncology, and genomic profiling has become a significant factor in allowing for personalised care. Tailored oncology. Navigating barriers to access.

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Genome Genomics Clinical Trials Clinical Trials 105

XTalks

SEPTEMBER 9, 2021

It was found that the gene being delivered through the therapy had integrated into the genomes of six of the seven mice that were administered the highest dose. Although a rare event that occurs at very low frequency, AAV vectors can integrate into genomes through homologous recombination.

Gene Therapy 105

Gene Therapy Gene Genome Genomics 105

XTalks

MAY 10, 2022

XTALKS WEBINAR: Harnessing Artificial Intelligence for Higher Quality Data in Preclinical Trials and Translational Research. Somatic variant classification and interpretation are the most time-consuming steps of tumor genomic profiling,” said the co-author of the study Marilyn M.

Bioinformatics 98

Bioinformatics Development Gene Genome 98

pharmaphorum

APRIL 23, 2020

to 13.30 (BST) / 07:30 to 08:30 (EST).

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Genome Genomics Life Science Clinical Trials 40

Drug Discovery World

SEPTEMBER 26, 2022

Indeed, having a safety profile already established could entice patients to enter clinical trials more readily than with ‘unknown’ compounds. . Panna Sharma is the President and CEO of Lantern Pharma, a company utilising artificial intelligence (AI), machine learning and genomics to advance the timeline of drug discovery and development.

Drugs 52

Drugs Genome Genomics Clinical Trials 52

Drug Discovery World

MARCH 2, 2023

” The role of AI in rare disease clinical trials might hold the key to helping the UK achieve this vision. .” ” The role of AI in rare disease clinical trials might hold the key to helping the UK achieve this vision.

Development 52

Development Drugs Clinical Trials Clinical Trials 52

pharmaphorum

DECEMBER 15, 2022

Co-chaired by Lord James O’Shaughnessy and Professor Mike Bewick, former deputy national medical director of NHS England (present online), the NHS Innovation and Life Sciences Commission Report launch took place at One Great George Street, Westminster, on 12th December 2022. The UK as a powerhouse of research.

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Life Science Medicine Clinical Trials Clinical Trials 97