Drug Discovery World

MAY 25, 2023

Several new products for the life sciences sector have been launched over the last month, from miniature semiconductor chip (MSC) technology to a new inhalation testing service. DDW provides an update.

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Drug Discovery World

APRIL 27, 2023

The report notes that the focus on science and pharma throughout the Covid-19 pandemic has resulted in the emergence of new locations as life science hubs and name checks Boston, Massachusetts and San Francisco, California as examples of centres with heightened investment appeal in the life sciences 1.

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Drug Discovery World

JANUARY 10, 2023

For over 50 years, Bethyl Laboratories (now a Fortis Life Sciences brand) has been dedicated to improving lives by supporting scientific discovery through qualified antibody products and custom services. This pillar requires that two or more antibodies directed against different epitopes of a protein generate similar results.

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XTalks

FEBRUARY 19, 2024

Moderna’s vaccine not only targets gB but also incorporates a second target, a five-unit protein complex vital for the virus’ ability to infect epithelial cells in the mouth and nose. 1990s: The earliest vaccine development efforts were on live attenuated vaccines and the targeting of specific CMV proteins such as gB.

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Drug Discovery World

JANUARY 23, 2024

The annual Genesis conference took place at the end of 2023 in London, bringing together key opinion leaders, investors and innovators from across the life sciences sector to exchange insights, debate trends and generate deals. What would Alexandra Gray like from the life sciences industry?

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XTalks

OCTOBER 21, 2020

The answer may lie in the genetic code of the virus, which scientists at Duke University have found contains several silent mutations that affect protein folding. The researchers focused on the spike proteins that protrude from the surface of the coronavirus, which are responsible for viral attachment and entry into host cells.

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Drug Discovery World

OCTOBER 26, 2023

The technologies cover the whole range of biomolecules from genes to protein to metabolites. With the ability to analyse thousands of proteins simultaneously, proteomics empowers scientists to reveal previously unknown protein interactions, pathways, and drug targets. phosphorylations or ubiquitinations).

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Drug Discovery World

FEBRUARY 21, 2023

At IBM Research, a group of scientists and researchers from around the globe is working to support the power of the scientific method to invent what’s next for IBM, its clients, and the world. This is episode two, Acquiring deeper insights and acceleration with AI. Joshua Smith, from the IBM T.J.

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Drug Discovery World

FEBRUARY 21, 2023

At IBM Research, a group of scientists and researchers from around the globe is working to support the power of the scientific method to invent what’s next for IBM, its clients, and the world. This is episode two, Acquiring deeper insights and acceleration with AI. Joshua Smith, from the IBM T.J.

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XTalks

APRIL 13, 2021

Now, thanks to a study funded by the National Institutes of Health Intramural Research Program, scientists have discovered that ?-synuclein, synuclein, a protein involved in the formation of amyloid deposits in the brain characteristic of Parkinson’s disease and other neurodegenerative disorders, is also implicated in melanoma.

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XTalks

JANUARY 6, 2021

One nanobody in particular, called NIH-CoVnb-112, was shown to be able to prevent COVID-19 infection from the novel coronavirus by targeting both the spike protein on SARS-CoV-2, as well as the angiotensin converting enzyme 2 (ACE2) receptor that it binds to on human cells. Related: Scientists Use Llama Antibodies to Neutralize COVID-19.

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The Pharma Data

MARCH 16, 2022

The research scientist at the Max Planck Institute for Medical Research received the award in recognition of his ground-breaking work in establishing various approaches to protein labeling in living cells that have enabled far-reaching advances in chemical and cell biology. Protein labeling (e.g.

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XTalks

DECEMBER 12, 2023

Plasma medicine is a critical and specialized field within healthcare, centering on the use of human plasma for the development and administration of life-saving treatments. Human plasma, the clear, liquid portion of blood, is composed of water, electrolytes, nutrients and crucial proteins such as antibodies, clotting factors and albumin.

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XTalks

JULY 14, 2022

For example, when T cells (a type of white blood cells that fight off infections and cancer) are activated in our immune systems, thousands of proteins in these cells change. The proteins are interconnected and changes in one protein level can impact that of another.

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XTalks

JANUARY 11, 2023

The new subvariant has also been dubbed “Kraken” by some scientists. on the horizon as scientists say the virus appears to be rapidly evolving , mutating faster than most viruses. Thanks to large-scale sequencing efforts, scientists in the US have been keeping a close eye on XBB. and its descendants.

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Pharmaceutical Technology

JULY 22, 2022

Muge Cevik, a clinical scientist, shared an article around the mystery of viral hepatitis cases in children. Peter Hotez’s tweet on PAI Life Sciences’ phase 1 trial of its snail fever vaccine. Username: Laurie Garrett. Twitter handle: @Laurie_Garrett. Likes: 521. Retweets: 118. Retweets: 113. Username: Prof Peter Hotez.

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Drug Discovery World

OCTOBER 16, 2023

Professor Emma Clark, Interim Head of Translational Health Sciences, says: “We perform world leading translational research in multiple health science areas including cardiovascular, endocrinology, neuroscience, musculoskeletal, regenerative and renal medicine.

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The Pharma Data

FEBRUARY 25, 2022

Several FDA-approved drugs – including for type 2 diabetes, hepatitis C and HIV – significantly reduce the ability of the Delta variant of SARS-CoV-2 to replicate in human cells, according to new research led by scientists at Penn State. ” The findings published today (Feb. 25) in the journal Communications Biology.

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pharmaphorum

JANUARY 11, 2023

To find potential drug candidates, disease-associated protein targets are tested against a small pool of less than ten million distinct chemotypes synthesised at great effort and expense over the past 100 years. Not an unambitious goal. Today’s pharmaceutical drug discovery process essentially relies on trial and error,” he expanded. “To

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Drug Discovery World

OCTOBER 20, 2023

Its proprietary technology, Proximity Extension Assay (PEA), provides high throughput protein analysis. Through the purchase, Thermo Fisher will also gain a library of more than 5,300 validated protein biomarker targets.

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Drug Discovery World

APRIL 11, 2023

The molecule, known as lissodendoric acid A, appears to counteract other molecules that can damage DNA, RNA and proteins and even destroy whole cells.

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The Pharma Data

NOVEMBER 10, 2020

“Paul is a seasoned leader with a significant track record of accomplishment in the life sciences industry,” said Chase Coffman, co-founder and CEO, Elektrofi. Headquartered in Boston, the company’s founding team of MIT engineers and scientists are shaping the future of biologics delivery. About Elektrofi. Source link.

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pharmaphorum

FEBRUARY 28, 2022

Studies have suggested that some patients with COVID-19 exhibit marked increases in autoantibody reactivities as compared to uninfected individuals, including some that seem to target immune components like cytokines, chemokines and complement proteins.

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Drug Discovery World

JULY 11, 2023

Tim Lowery , President, JSR Life Sciences, asks whether artificial intelligence can do for life sciences what it has done in other sectors and whether these tools can keep up with the complexities of human biology. So, where do we go from here to realise their potential in life sciences?

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pharmaphorum

APRIL 28, 2021

The results of the text mining report bring light to recently trending protein and genomic terms with a semantic relationship to pancreatic cancer, showing the emergence in research in both X-inactive specific transcript (XIST) and lincoo511 ( fig.1. Eric Gilbert is a life sciences consultant at Elsevier. About the author.

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Drug Discovery World

OCTOBER 20, 2022

Kawasaki King Skyfront is an R&D center with a focus on life science and environmental fields—and the realisation of open innovation projects. CELLINK Corporation, the Japanese subsidiary, was established in 2020 in Kansai, a region renowned for life sciences research facilities and corporations 3. .

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The Pharma Data

JANUARY 17, 2021

Highly experienced life sciences executive that brings large pharma and biotech experience. John will be joining the Board as the representative for Oxford Sciences Innovation (OSI), one of the Company’s major shareholders. OXFORD, England , Jan.

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The Pharma Data

DECEMBER 15, 2020

The Antigen ELISA is a laboratory test able to be applied in semi quantitative automatable detection of the SARS-CoV-2 nucleocapsid protein on a large scale. PerkinElmer enables scientists, researchers and clinicians to address their most critical challenges across science and healthcare. About PerkinElmer.

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Drug Discovery World

DECEMBER 13, 2023

This article is sponsored by Fortis Life Sciences. Fortis Life Sciences offers custom antibody discovery and manufacturing services for antibodies and single-domain antibodies, supporting the drug discovery market. Bethyl scientists will partner with your team to develop a bespoke antibody for your target and assay.

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Drug Discovery World

APRIL 3, 2023

As life science operates globally, the vision for the business was always to bring aptamers as an antibody alternative to researchers worldwide. What advice would you offer to similar start-ups?    AT: Integral to Aptamer Group’s offering is an in-depth understanding of molecular science.

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XTalks

AUGUST 25, 2021

It’s a practical tip that can be feasible for a number of people who are looking to improve their health, which is top of mind for many people,” said Yanping Li, a senior research scientist at the department of nutrition at Harvard’s T.H. Chan School of Public Health, and lead investigator of this research, in a press release.

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XTalks

JUNE 2, 2021

The KRAS gene encodes the K-Ras protein which is part of the Ras family of small GTPases that act as molecular messengers that relay signals into the nucleus. NSCLC accounts for approximately 84 percent of the 2.2 million new lung cancer diagnoses each year worldwide, including approximately 236,000 new cases in the US.

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XTalks

AUGUST 5, 2020

p-tau217 is a type of tau protein that forms the primary component of neurofibrillary tangles, which accumulate in the brain to give rise to the condition. The blood test can specifically detect the presence of this tau protein at significantly earlier stages, leading to the possibility of early diagnosis and treatment.

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Protein Research Development Life Science 66

pharmaphorum

OCTOBER 11, 2022

Tunnah began his career as a scientist, studying biochemistry right through to PhD at the University of Oxford, his work at that time concerning very early stage, novel anti-cancer therapies (or ‘structural biophysics’). The first of those had been Tunnah’s own springboard away from academia: communication. An omnichannel information age.

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Drug Discovery World

NOVEMBER 28, 2023

Scientists at the University of Bath have developed a way of joining up the head and tail of a protein, making it more stable and easier to get into cells. Drug treatments often work by binding to proteins involved in disease and blocking their activity, which either reduces symptoms or treats the disease.

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XTalks

JULY 29, 2021

These include tau (t-tau); neurofilament light (NfL); glial fibrillary acid protein (GFAP); ubiquitin carboxyl-terminal hydrolase L1 (UCH-L1); and species of amyloid beta (A?40, Neuroinflammation, injury to the brain, neurodegeneration and Alzheimer’s disease are associated with certain biological markers that can be detected in the blood.

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XTalks

OCTOBER 22, 2020

Internet of Things (IoT) devices and cloud technologies allow process experts and data scientists to work together to increase process understanding and design analytical tools to maintain the processes under a defined state of control.

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