Pharmaceutical Technology

JULY 7, 2022

Often referred to as a type of gene-modified cell therapy, CAR-T cell therapies involve genetically modifying a patient’s own T cells to produce a protein that enables them to identify and kill cancer cells.

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Pharmaceutical Technology

MAY 15, 2023

They also inhibit tubulin protein to induce apoptosis in cancer cells. Other targets such as DNA topoisomerase enzyme, protein kinases, and miscellaneous targets including Cdc25, mitochondrial enzymes, HDAC, LSD1, HPV E2 TAD, NQO1, aromatase, BCl-6, estrogen receptor, GRP-78, and Keap-Nrf2 pathway are inhibited by oxazole derivatives.

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XTalks

MAY 10, 2023

The company’s products are gluten-free, vegan and high in fiber and protein. The company’s products can be found in major retailers, convenience stores and pharmacies across the US. Hippeas’ products come in a variety of flavors like white cheddar, sriracha sunrise and bohemian barbecue.

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XTalks

JANUARY 8, 2024

This accumulation triggers inflammation and damages kidney tissues, leading to the leakage of blood and protein into the urine. Related: Filspari (Sparsentan) Rare Kidney Disease Drug Gets FDA Approval Availability and Price of Tarpeyo Tarpeyo is available solely through Biologics by McKesson, Calliditas’ specialty pharmacy.

FDA Approval 64

FDA Approval Clinical Trials Clinical Trials Nurses 64

Delveinsight

AUGUST 26, 2021

Shape’s RNA editing technologies can modify the RNA sequence, which makes the body’s protein building blocks. Shape’s RNA editing technology could potentially modify the amount of a key regulatory protein in the body or treat genetic diseases.

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Vaccination Vaccine Gene Therapy RNA 98

XTalks

OCTOBER 15, 2020

After struggling to create the ideal recipe, Love Good Fats is now present and distributed across North America in more than 20,000 retailers such as Walmart, Whole Foods Market, Sprouts, Kroger, CVS Pharmacy and Costco. The brand’s products include the original truffle style, chewy and nutty protein bar along with a range of creamy shakes.

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pharmaphorum

NOVEMBER 9, 2022

Haemophilia is a rare genetic bleeding disorder, occurring in one in every 5,000 (Haemophilia A) to 30,000 (Haemophilia B) male births, and is associated with an increased bleeding tendency due to a deficiency of blood clotting proteins, called coagulation factors, which are needed for the blood to clot.†. References. Berntorp E.,

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The Pharma Data

NOVEMBER 22, 2020

from the Purdue University College of Pharmacy. The company is advancing a broad, diversified pipeline of multiple, selective small molecule therapeutics for highly sought-after disease-causing target proteins in oncology and immunology. Mr. Hatfield holds an MBA from The Wharton School, University of Pennsylvania, and a B.S.

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Life Science Medicine Pharmacy Doctors 52

Intouch Solutions

JUNE 30, 2022

CVS aims to be first pharmacy in the metaverse (Pymnts.com) – CVS has filed a patent to sell goods and provide healthcare services in the virtual world. If major pharmacies like CVS are planning for the metaverse, pharma manufacturers should be fast followers! Would it feel strange to get a prescription for VR?

Pharmacy 52

Pharmacy Radiology Cosmetics Manufacturing 52

XTalks

FEBRUARY 8, 2021

They include proteins, monoclonal antibodies and vaccines that are considered to be “ highly similar ” to biological products that have already been approved by the FDA. What is a Biosimilar? Biosimilars are the “generic” drugs of the biopharma world. What is an Interchangeable Biological Product?

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Production Insulin Branding Generic Drugs 78

Drug Discovery World

NOVEMBER 8, 2023

They used an AI tool called AlphaFold to understand the structure of a protein called CDK20 4 , which is associated with liver cancer. She started her journey in the field of pharmaceutical research at Pfizer and holds a Master’s degree in Pharmacy from the University of Mumbai.

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Clinical Trials Clinical Trials Trials Drugs 70

pharmaphorum

JUNE 17, 2022

The active drug is nirmatrelvir, a protease inhibitor, which helps keep the SARS-CoV-2 protein from replicating. The federal government oversees the allocation to state health departments for distribution to pharmacies, hospitals, urgent cares and other entities. How does the drug work?

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The Pharma Data

NOVEMBER 16, 2020

The stability at refrigerated conditions allows for storage at most pharmacies, hospitals, or physicians’ offices. No Dilution Required at Vaccination Site: The vaccine will not require onsite dilution or special handling, which facilitates vaccination across a range of settings including pharmacies and physicians’ offices.

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Vaccination Vaccine Containment Pharmacy 52

Druggist

APRIL 29, 2021

Apixaban stops the production of enzymes (chemicals) required for the production of fibrin , a compound (protein) that plays a role in the clotting of the blood. Pharmacies in the UK can also be offered a free NHS service called New Medication Service (NMS).

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XTalks

JULY 28, 2020

Now, results from a new study conducted by researchers at the UC San Francisco (UCSF) School of Pharmacy and the Novartis Institutes for BioMedical Research (NIBR), have challenged drugmakers’ understanding of the effects of excipients.

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Protein Drugs In-Vitro Scientist 103

The Pharma Data

NOVEMBER 20, 2020

Zokinvy blocks the accumulation of defective, farnesylated proteins which form tight associations with the nuclear envelope, leading to cellular instability and the process of premature aging in children and young adults with Progeria and processing-deficient Progeroid Laminopathies. ABOUT ZOKINVY (LONAFARNIB). LIMITATIONS OF USE.

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FDA Approval Genetics Clinical Trials Clinical Trials 52

Druggist

FEBRUARY 17, 2021

In this post, I will review the best ointment or cream for insect bites available over the counter and from pharmacies. Products available for insect bites in supermarkets or pharmacies come almost entirely in the form of creams. For many customers, ointment or cream for insect bites is the first line of rescue in stings management.

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The Pharma Data

JANUARY 17, 2021

And the company supplies tools, information and services that enable hospitals, pharmacies and healthcare professionals to efficiently deliver expert medical care. . BARCELONA, Spain , Jan. 18, 2021 /PRNewswire/ — Grifols (MCE: GRF, MCE: GRF.P,

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Clinical Trials Clinical Trials Trials Containment 52

XTalks

MARCH 28, 2024

Winrevair is an activin signaling inhibitor that binds to activin proteins that are overproduced in PAH. The proteins induce the walls of blood vessels to grow and thicken over time, stressing the heart to work harder to pump blood which can eventually lead to heart failure.

FDA Approval 81

FDA Approval Clinical Trials Clinical Trials Trials 81

The Pharma Data

DECEMBER 5, 2020

BCMA (B-cell maturation antigen) is a protein that is typically over-expressed on multiple myeloma cells. (NASDAQ: REGN) today announced updated data for REGN5458, a BCMAxCD3 bispecific antibody, from the Phase 1 portion of a Phase 1/2 trial in patients with relapsed or refractory (R/R) multiple myeloma. and the world, respectively, in 2020.

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The Pharma Data

OCTOBER 30, 2020

The two potent, virus-neutralizing antibodies that form REGN-COV2 bind non-competitively to the critical receptor binding domain of the virus’s spike protein, which diminishes the ability of mutant viruses to escape treatment and protects against spike variants that have arisen in the human population, as detailed in Science.

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Production Antibody Manufacturing Trials 52

pharmaphorum

AUGUST 10, 2020

Evrysdi is designed to treat SMA by increasing production of the survival of the motor neuron (SMN) protein. SMN protein is found throughout the body and is critical for maintaining healthy motor neurons and movement. A liquid medicine, Evrysdi is administered daily at home by mouth or feeding tube.

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FDA Approval Drugs Gene Therapy Protein 59

XTalks

FEBRUARY 8, 2024

for a one-month supply Why it did so well: Jardiance belongs to a class of drugs known as sodium-glucose co-transporter 2 (SGLT2) inhibitors, inhibiting the SGLT2 protein in the kidneys to lead to the excretion of excess glucose through the urine. Jardiance brought in $2.06 billion for Eli Lilly and $6.23 billion for Boehringer Ingelheim.

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Sales Insulin FDA Approval Drugs 52

Drug Discovery World

APRIL 14, 2023

Jaffee’s award lecture will be held on Monday April 17 at 4:45pm ET. Delattre’s award lecture will be held on Tuesday April 18 at 5pm ET.

Genetics 52

Genetics Research Medicine Clinical Research 52

The Pharma Data

OCTOBER 28, 2020

The two potent, virus-neutralizing antibodies that form REGN-COV2 bind non-competitively to the critical receptor binding domain of the virus’s spike protein, which diminishes the ability of mutant viruses to escape treatment and protects against spike variants that have arisen in the human population, as detailed in Science.

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Antibody Trials Production Clinical Trials 40

The Pharma Data

SEPTEMBER 30, 2021

” To solve those problems, Varadarajan collaborated with Xinli Liu, professor of pharmaceutics at the UH College of Pharmacy, and an expert in nanoparticle delivery. Liu’s team was ready to encapsulate the agonist of the stimulator of interferon genes (STING) within liposomal particles to yield the adjuvant named NanoSTING.

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Vaccination Vaccine Immune Response Licensing 52

The Pharma Data

DECEMBER 17, 2020

The two potent, virus-neutralizing antibodies that form the cocktail bind non-competitively to the critical receptor binding domain of the virus’s spike protein, which diminishes the ability of mutant viruses to escape treatment and protects against spike variants that have arisen in the human population, as detailed in Science.

Antibody 52

Antibody Medicine Production Trials 52

XTalks

AUGUST 30, 2022

What About Small Proteins and Antibodies Reaching Extracellular CNS Targets? Ancillary services are also needed, such as a pharmacy to store, prepare and deliver the IP and labs such as a CSF lab to prepare samples.”. All facilities (such as lab, pharmacy, MRI, etc.) The main investigator core team is depicted in the middle.

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Trials Drug Delivery Drugs Gene 83

The Pharma Data

JANUARY 12, 2021

The two potent, virus-neutralizing antibodies that form the cocktail bind non-competitively to the critical receptor binding domain of the virus’s spike protein, which diminishes the ability of mutant viruses to escape treatment and protects against spike variants that have arisen in the human population, as detailed in Science.

Antibody 52

Antibody Production Manufacturing Clinical Trials 52

The Pharma Data

MARCH 21, 2022

“Inhibiting that proteasome makes it a great anti-cancer agent,” said Bauman, speaking of the protein complex that degrades useless or impaired proteins. Salisporamide has a long history at Scripps and UC San Diego. But there’s another type of proteasome found in immune cells.

Bacterium 52

Bacterium Scientist Clinical Trials Clinical Trials 52

The Pharma Data

DECEMBER 29, 2020

The two potent, virus-neutralizing antibodies that form the cocktail bind non-competitively to the critical receptor binding domain of the virus’s spike protein, which diminishes the ability of mutant viruses to escape treatment and protects against spike variants that have arisen in the human population, as detailed in Science.

Antibody 52

Antibody Trials Production Clinical Trials 52

pharmaphorum

DECEMBER 7, 2021

Viagra (sildenafil) – originally developed by Pfizer – is now widely available as a generic and can even be bought from pharmacies over-the-counter in some countries. Sildenafil is also sold as Revatio to treat pulmonary artery hypertension (PAH).

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Drugs Clinical Trials Clinical Trials Scientist 52

XTalks

JUNE 12, 2023

In addition to dialysis treatments, Fresenius Medical Care offers a range of healthcare services including value and risk-based care programs, pharmacy services and services related to vascular, cardiovascular and endovascular specialties, as well as ambulatory surgery centers.

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The Pharma Data

NOVEMBER 18, 2020

” The monoclonal antibody is a man-made protein that acts like a human antibody in the immune system. It works to block the “spike protein” in the virus before it can enter human cells and cause illness. USF HEALTH USF Health’s mission is to envision and implement the future of health.

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Antibody Medicine Radiology Protein 40

Pfizer

DECEMBER 20, 2022

Current variants of concern can be resistant to treatments that work by binding to the spike protein found on the surface of the SARS-CoV-2 virus. Microsomal triglyceride transfer protein inhibitor: lomitapide. In preclinical studies, nirmatrelvir did not demonstrate evidence of mutagenic DNA interactions. Investor Relations. +1

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The Pharma Data

NOVEMBER 20, 2020

The two potent, virus-neutralizing antibodies that form the cocktail bind non-competitively to the critical receptor binding domain of the virus’s spike protein, which diminishes the ability of mutant viruses to escape treatment and protects against spike variants that have arisen in the human population, as detailed in Science.

Antibody 52

Antibody Production Clinical Trials Clinical Trials 52

The Pharma Data

NOVEMBER 21, 2020

The two potent, virus-neutralizing antibodies that form REGEN-COV2 bind non-competitively to the critical receptor binding domain of the virus’s spike protein, which diminishes the ability of mutant viruses to escape treatment and protects against spike variants that have arisen in the human population, as detailed in Science.

Antibody 40

Antibody Production Clinical Trials Clinical Trials 40