pharmaphorum

MAY 13, 2022

Around 4,500 women in the UK will be eligible for treatment with Gedeon Richter’s once-daily oral therapy Ryeqo, after NICE backed the GnRH antagonist to treat heavy menstrual bleeding associated with uterine fibroids. Pfizer agreed a $4.2

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The Pharma Data

OCTOBER 14, 2021

Today, Novartis announced data demonstrating the safety of Kesimpta ® (ofatumumab) over extended exposure (~3.5 Today, Novartis announced data demonstrating the safety of Kesimpta ® (ofatumumab) over extended exposure (~3.5 About Novartis Novartis is reimagining medicine to improve and extend people’s lives.

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pharmaphorum

AUGUST 24, 2020

Could collecting, understanding, and disseminating patient-reported outcomes during trials be the key to advancing oncology treatments and improving cancer outcomes? . Said the team behind the portal: “The aim is to show patient-reported symptom data consistently from select cancer clinical trials of approved products.

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XTalks

JANUARY 5, 2024

Eli Lilly launched LillyDirect this week, an online service that provides access to the company’s medicines, including its newly approved weight loss drug Zepbound (tirzepatide). The letter also addressed the safety risks associated with the use of compounded tirzepatide. Ricks, Lilly’s chair and CEO, in the company’s announcement.

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Drugs Pharmacy Cosmetics Insulin 59

XTalks

FEBRUARY 3, 2023

The US Food and Drug Administration (FDA) has approved the first and only oral drug for the treatment of advanced or metastatic breast cancer in postmenopausal women or adult men with estrogen receptor-positive (ER+), human epidermal growth factor receptor 2-negative (HER2-) ESR1 mutations.

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XTalks

MAY 31, 2023

Headquartered in California, Acelyrin is a late-stage clinical biopharmaceutical company dedicated to expediting the development and delivery of groundbreaking medicines in the field of immunology. Lonigutamab is currently undergoing evaluation for the treatment of thyroid eye disease in a Phase II trial.

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Clinical Trials Clinical Trials Trials Production 97

The Pharma Data

APRIL 28, 2021

More than 50% of confirmed disability worsening events in newly diagnosed, treatment-naïve RMS patients were PIRA, an emerging endpoint used in MS trials to measure disability worsening independent of relapses, indicating that disease progression starts early 1. You should not place undue reliance on these statements.

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XTalks

OCTOBER 22, 2020

In this sense, pharmaceutical companies have developed different strategies to produce a wide variety of advanced therapy medicinal products (ATMP) and biological products, such as monoclonal antibodies, recombinant proteins, gene therapy viral vectors, CAR-T cells and oncolytic viruses, in order to deliver new medical needs in our society.

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The Pharma Data

APRIL 19, 2022

Food and Drug Administration (FDA) has approved commercial production at the company’s new CAR T-cell therapy manufacturing facility in Frederick, Maryland. from apheresis to finished product, which includes many processes that are heavily regulated for safety.”.

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The Pharma Data

AUGUST 5, 2020

Ofatumumab is a targeted B-cell therapy that delivers superior efficacy with a similar safety profile when compared with teriflunomide, a commonly prescribed oral treatment for multiple sclerosis 1 . Showed the annual rate of brain volume loss was not significantly different (MRI-related secondary endpoint) 1. 10% of patients 1,3.

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Druggist

APRIL 16, 2021

For many customers, throat numbing lozenges are the first choice in the management of sore and irritated throat. Sore throat lozenges, which contain a local anaesthetic as an active ingredient, are classified as pharmacy-only products (P). P products can only be purchased from the pharmacy counter and online chemists. .

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Druggist

MAY 22, 2021

Today I will look into the use of Gaviscon in pregnancy by looking at the main recommendations of heartburn treatment in pregnancy. I will conclude which particular Gaviscon product is the best to use in the pregnancy. . Gaviscon is a brand name of a medicine called antacid. Summary: What is Gaviscon? Gaviscon range.

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Containment Production Pharmacy Medicine 52

Druggist

OCTOBER 8, 2020

PPIs are the most effective drug in stopping the production of stomach acid. Treatment Zollinger–Ellison syndrome Treatment of Gastro-oesophageal reflux disease (GORD) Verdict : both lansoprazole and omeprazole have the same licensed use as listed above. A proton pumps action the last stage of stomach acid production.

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The Pharma Data

NOVEMBER 24, 2020

25, 2020 /CNW/ – On August 21, 2020 , Health Canada approved Lynparza® (olaparib), for the treatment of adult patients with deleterious or suspected deleterious germline and/or somatic BRCA or ATM- mutated metastatic castration-resistant prostate cancer (mCRPC) who have progressed following prior treatment with a new hormonal agent (NHA).

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Druggist

DECEMBER 13, 2020

Its use is not just restricted to the treatment of depression. Amitriptyline is one of the first options considered when a drug treatment is needed to help manage neuropathic pain. Nerve pain – recommended pharmacological treatment. Nerve pain – recommended pharmacological treatment . pregabalin.

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Drugs Medicine Licensing Licensing 83

XTalks

APRIL 24, 2023

Out of over 7,000 rare diseases, only 5 percent (or less) of rare diseases are thought to have approved treatment options, known as “orphan” therapies. Thankfully, we can anticipate that many more of these new treatments are expected in the future.” However, there is reason to be hopeful.

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Gene Therapy Gene Trials Clinical Trials 95

The Pharma Data

FEBRUARY 1, 2021

Food and Drug Administration (FDA) has approved a new intramuscular (IM) injection route of administration for Plegridy ® ( peginterferon beta-1a ) for the treatment of relapsing forms of multiple sclerosis (MS). Access to and availability of treatment options have become increasingly important in the current COVID-19 environment.

FDA Approval 40

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The Pharma Data

APRIL 1, 2021

Food and Drug Administration (FDA) has approved Sarclisa ® (isatuximab) in combination with carfilzomib and dexamethasone (Kd), for the treatment of adult patients with relapsed or refractory multiple myeloma (RRMM) who have received one to three prior lines of therapy. “In PARIS – March 31, 2021 – The U.S. Martin, M.D., Adamson, M.D.,

FDA Approval 52

FDA Approval Clinical Trials Clinical Trials Antibody 52

Druggist

JANUARY 15, 2021

Paracetamol, one of the most prescribed drugs in the UK , and probably the most popular over the counter medicine has been recently subject to shortages due to increased demand in recent months. Combination products containing paracetamol. Paracetamol is one of few medicines which can be used in pregnancy. . nerve pains .

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The Pharma Data

NOVEMBER 2, 2020

for the Treatment of Achondroplasia. This acceptance by the FDA marks the first marketing application accepted for a treatment for achondroplasia in the United States. The study will be followed by a subsequent open-label extension trial when all subjects receive active treatment. If approved, 1st Therapy in U.S.

Drugs 40

Drugs Containment Trials Marketing 40

Druggist

NOVEMBER 19, 2020

The Medicines and Healthcare products Regulatory Agency (MHRA) recommends that LABA should always be taken with inhaled corticosteroids. For less common side effects, please refer to product information leaflet. When used in treatment in the maintenance of asthma, Fostair is used twice a day. Dysphonia (voice hoarseness).

Pharmacy 69

Pharmacy Doctors Doctor Licensing 69

Drug Discovery World

OCTOBER 19, 2022

To this end, R&D teams are investigating innovative drug delivery systems that can not only maximise the chances of successfully bringing a new API to market, but also improve the efficacy of APIs that have already been used in approved drug products 4. . Consider drug delivery systems early on .

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The Pharma Data

SEPTEMBER 1, 2020

.–( BUSINESS WIRE )– Bristol Myers Squibb (NYSE:BMY) today announced interim results from the Phase 3 open-label extension trial DAYBREAK, demonstrating the long-term efficacy and safety profile of Zeposia (ozanimod) in patients with relapsing forms of multiple sclerosis (MS). months while in DAYBREAK.

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Trials Clinical Trials Clinical Trials Vaccination 52

pharmaphorum

OCTOBER 2, 2020

“For the pharmaceutical industry, responsible self-care is crucial to ensuring a healthy population that is health literate, understands self-treatment and practices it effectively”. Meanwhile, almost half of those surveyed say they are now more likely to treat illness with over-the-counter medicines instead of going to their GP.

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The Pharma Data

DECEMBER 27, 2020

This year has been difficult, but it has reinforced the importance of our mission: to treat and potentially even reverse the effects of serious diseases and conditions by advancing our novel cell therapy product candidates through clinical trials and into the hands of physicians.

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Manufacturing Production Development Clinical Trials 52

The Pharma Data

DECEMBER 11, 2020

We founded BioNTech to develop new technologies and medicines that utilize the full potential of the immune system to fight serious diseases,” said Ugur Sahin, M.D., The Data Monitoring Committee for the study has not reported any serious safety concerns related to the vaccine. CEO and Co-founder of BioNTech.

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Vaccination Vaccine Clinical Trials Clinical Trials 52

The Pharma Data

AUGUST 3, 2021

Product sales increased 3% globally, driven by double digit volume growth across a number of our products including Prolia ® (denosumab), Repatha ® (evolocumab) and our biosimilar products MVASI ® (bevacizumab-awwb) and KANJINTI ® (trastuzumab-anns). Product Sales Performance. driven by the write-off of $1.5

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Drug Discovery World

OCTOBER 18, 2022

This is especially true of immunotherapy, a field that edges ever closer to the holy grail of personalised medicine and is showing real promise for treating certain malignancies. These soluble TCR products do not require costly personalised therapy in the way that TCR-T cell treatments do. . For example, it demonstrated a 9.3%

Life Science 52

Life Science Engineer Research Clinical Trials 52

XTalks

DECEMBER 12, 2023

They offer insights into safety that go beyond what standard medical tests provide. Perhaps most crucially, biomarkers are beginning to serve as surrogate endpoints in neuroscience trials, forecasting the potential clinical benefits of a treatment. It can identify potential safety concerns that might deem a participant ineligible.

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Trials Clinical Trials Clinical Trials Genetics 111

Druggist

SEPTEMBER 7, 2020

Over the counter sleeping pills UK: active ingredients All products available over the counter ‘for sleeping’ contain sedative antihistamines as the main active ingredient. However, it has been documented that when used regularly, tolerance develops rapidly (Vande Griend, Anderson, 2003), within a few days of starting the treatment.

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Containment Pharmacy Licensing Licensing 94

Pharmaceutical Technology

AUGUST 3, 2022

The discovery of a new chemical entity (NCE) that could potentially lead the way to a ground-breaking therapeutic treatment is an exciting prospect for any chemist. During this stage, a team of lab technicians must identify the best way to manufacture the active pharmaceutical ingredient (API) into a suitable dosage form for pilot production.

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XTalks

AUGUST 30, 2022

Previously Existing Treatments for Hemophilia A. The other treatment products are non-factor replacement therapies which use medications to treat the disorder. Some examples of hemophilia A medications are: Hemlibra (emicizumab), an antibody for the treatment of hemophilia A in adult and pediatric patients.

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Gene Therapy Gene Clinical Trials Clinical Trials 98

The Pharma Data

MARCH 3, 2022

Multiple Sclerosis Journal has published data from the ALITHIOS open-label extension study which provide a robust picture of the continuous safety data for Kesimpta, showing it was well tolerated in ~2000 patients with up to 3.5 The overall incidence of serious infections was low and no new safety risks were identified.

Antibody 52

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The Pharma Data

OCTOBER 9, 2021

Remibrutinib is a highly selective, potent oral BTK inhibitor with a potential best-in-class profile 1 Late-breaking safety data will be presented, including outcomes of COVID-19 in relapsing forms of multiple sclerosis (RMS) patients treated with Kesimpta 2 , and effects of Kesimpta on immunoglobulin levels and risk of infection based on ~ 3.5

Immune Response 52

Immune Response Vaccination Vaccine Medicine 52

The Pharma Data

OCTOBER 6, 2021

Remibrutinib is a highly selective, potent oral BTK inhibitor with a potential best-in-class profile 1 Late-breaking safety data will be presented, including outcomes of COVID-19 in relapsing forms of multiple sclerosis (RMS) patients treated with Kesimpta 2 , and effects of Kesimpta on immunoglobulin levels and risk of infection based on ~ 3.5

Immune Response 52

Immune Response Medicine Vaccination Vaccine 52

Druggist

MAY 6, 2021

Metformin is the most commonly prescribed medication for the treatment of diabetes in the UK. As with other drugs, it is possible to experience side effects during the treament or medicine may not be suitable. Metformin is generally perceived as a ‘gold standard for the treatment of diabetes. What is metformin?

Insulin 98

Insulin Branding Drugs Licensing 98

Druggist

AUGUST 14, 2020

Gaviscon range of products is probably the most known brand of antacids in the UK. There are, however, several alternative products and drugs which can be used to help with symptoms of heartburn and indigestion. Today I will review 16 best Gaviscon alternative products and medicines.

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