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Obesity represents a catastrophic failure of government policy, public health, and medicine

World of DTC Marketing

There is disagreement whether obesity is really considered a disease or a behavioral risk factor, similar to smoking, alcohol, and substance abuse that may lead to disease. Obesity is a multifactorial disease in which environmental conditions and several genes play an important role in developing this disease.

Medicine 193
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AbbVie Advances Upadacitinib (RINVOQ®) to Phase 3 Clinical Trials in Systemic Lupus Erythematosus

The Pharma Data

1 The SLEek study met the primary endpoint of SLE Responder Index (SRI-4) and steroid dose less than or equal to 10 mg prednisone equivalent once per day at week 24 in the upadacitinib 30 mg group. “Systemic lupus erythematosus is a very unpredictable life-long condition and the way it affects a patient can change over time.

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Medical Informatics and Rare Disease: a bridge between two worlds

pharmaphorum

Today’s rare disease landscape comprises of around 7,000 different diseases. As the severity, progress, and treatment potential of rare diseases varies from patient to patient, each condition is going to need to be addressed differently using specific expertise. “As Navigating rare disease research and treatment.

Genome 104
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New Literature Review Highlights Economic Benefits Associated with Achieving Rheumatoid Arthritis Remission

The Pharma Data

AbbVie moment blazoned the publication of results from a new literature review in Advances in Therapy. “People with rheumatoid arthritis not only witness a significant physical and emotional burden, but this habitual, progressive complaint is also associated with a substantial fiscal impact,” said SepidehF. .

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NICE makes J&J’s Tremfya more accessible in England and Wales

pharmaphorum

The earlier guidance meant that use of the drug was restricted to patients with a body surface area of at least 3% affected by plaque psoriasis and a Psoriasis Area and Severity Index (PASI) score greater than 10. Active PsA is defined as peripheral arthritis with three or more tender joints and three or more swollen joints.

Drugs 52
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Positive data from two Phase 3 Dupixent® (dupilumab) trials in prurigo nodularis published in Nature Medicine

The Pharma Data

These first published Phase 3 results in this disease show Dupixent significantly reduced itch (the primary endpoint) and skin lesions compared to placebo. The disease is often painful, with burning, stinging and tingling of the skin and can negatively affect mental health, activities of daily living and social interactions.

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Saphnelo (anifrolumab) approved in the US for moderate to severe systemic lupus erythematosus

The Pharma Data

In these trials, more patients treated with Saphnelo experienced a reduction in overall disease activity across organ systems, including skin and joints, and achieved sustained reduction in oral corticosteroid (OCS) use compared to placebo, with both groups receiving standard therapy. 7,8,9,10,11. 12,13,14,15.

Trials 52