pharmaphorum

OCTOBER 3, 2022

Most patients are only now being enrolled in Europe, according to co-chief executive officers of Amylyx Justin Klee and Joshua Cohen, who say they arrived at the price following discussions with patients, as well as insurers and other stakeholders, but also mindful of future funding of research. ALS affects over 30,000 people in the US.

Drugs 52

Drugs Generic Drugs FDA Approval Trials 52

Rethinking Clinical Trials

MARCH 28, 2023

is funded by PCORI and was launched almost 10 years ago. It is an independent, nonprofit, research institute and leading funder of patient-centered comparative clinical effectiveness research (CER). Are there ways it can work more smoothly, take advantage of technology, have more consumer information that can facilitate these efforts?

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Clinical Trials Clinical Trials Trials Research 130

World of DTC Marketing

NOVEMBER 3, 2020

An #NHLBI-funded study put a price tag on American’s bad eating habits: $50 billion a year in health care costs, attributable to cardiometabolic diseases such as heart disease, stroke and type 2 diabetes.

Pharma Companies 190

Pharma Companies Scientist Medicine Research 190

Rethinking Clinical Trials

AUGUST 23, 2022

There is a national priority to increase diversity in clinical trials, from regulatory, funding agencies, industry, and others, so that the participant population reflects the U.S. Duke University School of Medicine. Diversity, Inclusion. Key Points. population at large, which is steadily becoming more diverse. Learn more.

Clinical Trials 130

Clinical Trials Clinical Trials Trials Medicine 130

pharmaphorum

NOVEMBER 19, 2021

million price tag make it is the most expensive treatment ever approved for NHS funding. Zolgensma meanwhile has been recommended for some babies aged up to 2 months with type 1 SMA and for treating pre-symptomatic SMA, even though the gene therapy’s £1.79

Drugs 98

Drugs Gene Therapy Genetic Disease Gene 98

XTalks

OCTOBER 28, 2021

The release of the cake mix comes just weeks after Perfect Day secured another $350 million from a Series D funding round led by the Canada Pension Plan Investment Board and Temasek Holdings. The latest investment brings the company’s total funding amount to $711.5 percent from 2019 to 2025.

Protein 98

Protein Packaging Packaging DNA 98

Rethinking Clinical Trials

SEPTEMBER 30, 2022

The trial was part of a “Pay for Success” contract that enabled the state to promise funds for further expansion conditional on positive evidence of impact from the randomized trial. We are largely looking at state data but are thinking about federal data that we can access. pctGR, @Collaboratory1.

Nurses 130

Nurses Trials Clinical Trials Clinical Trials 130

The Pharma Data

JANUARY 31, 2021

The Coalition for Epidemic Preparedness Innovations (CEPI) has committed to fund Clover’s S-Trimer COVID-19 vaccine candidate through licensure with a total investment of up to $328 million , a portion of which will support the global Phase 2/3 study. About Trimer-Tag© Technology. —- End —-.

Clinical Trials 52

Clinical Trials Clinical Trials Vaccination Vaccine 52

pharmaphorum

JUNE 12, 2022

Beti-cel has already been approved for marketing in Europe as Zynteglo, with a price tag of around $1.8 million for each one-shot therapy, but bluebird decided to take it off the market and exit the EU market altogether, blaming reluctance by payers to fund treatment. Eli-cel was also previously approved in Europe as Skysona.

Gene Therapy 59

Gene Therapy Gene Marketing Trials 59

XTalks

JULY 16, 2021

But yet, the price tag is still higher than real meat. Most companies in the field have been largely funded by venture capital so far, which only magnifies these costs. A pound of Beyond Meat’s Beef burgers carries a price tag of $6.25, Vox reported. Turning a Profit. Wouldn’t the higher demand lower plant-based meat prices ?

Protein 105

Protein Production Manufacturing Branding 105

The Pharma Data

JANUARY 31, 2021

The Coalition for Epidemic Preparedness Innovations (CEPI) continues to support Clover’s COVID-19 vaccine candidate and will fund its development through licensure. Utilizing Clover’s proprietary Trimer-Tag© technology, S-Trimer is a trimeric SARS-CoV-2 spike (S)-protein subunit vaccine candidate.

Vaccination 52

Vaccination Vaccine Trials Protein 52

pharmaphorum

JUNE 2, 2021

NICE has rejected routine NHS funding for Roche’s Evrysdi (risdiplam) for spinal muscular atrophy drug in draft guidance, a decision which doesn’t come as a surprise to patient association SMA UK. “NICE’s initial ‘no’ to approving risdiplam for NHS funding is not unexpected,” said SMA UK this morning.

Gene Therapy 52

Gene Therapy Gene Drugs Medicine 52

The Pharma Data

DECEMBER 3, 2020

The Phase 1 clinical trial was funded by the Coalition for Epidemic Preparedness Innovations (CEPI). Utilizing Clover’s proprietary Trimer-Tag © technology, S-Trimer is a trimeric SARS-CoV-2 spike (S)-protein subunit vaccine candidate. About Trimer-Tag © Technology. About COVID-19 S-Trimer Vaccine.

Vaccination 52

Vaccination Vaccine Immune Response Protein 52

Delveinsight

FEBRUARY 9, 2021

The funding will help to create and launch Riverway Discoveries. Through Riverway, Deerfield plans to fund selected projects and provide operational support. For the same reason, Deerfield has decided to invest USD 130 Million over the next ten years at Dana-Farber.

FDA Approval 52

FDA Approval Marketing Research Protein 52

pharmaphorum

JANUARY 21, 2022

Flawed funding model. This evolution is leading to additional health benefits and health gains, but they are accompanied by major concerns, as very high price tags raise questions about their affordability.”. In recent years, revolutionary medicines have come with price tags to match, but this is simply a symptom of our current model.

Medicine 52

Medicine Marketing Manufacturing Production 52

XTalks

JUNE 8, 2021

With a price tag of over $2.5 Due to its high list price, both NICE and the Scottish Medicines Consortium also recommended that the NHS fund the treatment and came to an agreement with the government health agency over a confidential discount. million, Zolgensma is currently the world’s most expensive drug.

Gene Therapy 110

Gene Therapy Gene Protein Trials 110

pharmaphorum

AUGUST 18, 2022

million price tag attached to the therapy when it was first made available in Europe, and is also well above the proposed $2.1 It slashed its workforce by 30% to reduce cash burn and extend its funded operations into the first half of 2023, so investors will be looking for signs of take-up of Zynteglo in the coming months.

Gene Therapy 52

Gene Therapy FDA Approval Gene Clinical Trials 52

pharmaphorum

JANUARY 31, 2023

Given the high price tags placed on many medications, it’s easy to understand why patients often feel that they are being taken advantage of. As patients experience first-hand the effectiveness reported in clinical trials, trust in the validity of these trials and the intentions of the pharmaceutical companies that fund them improves.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Vaccination 52

Drug Discovery World

JANUARY 30, 2024

Other Challenges: Limited insurance coverage: Many insurance companies are hesitant to cover CGTs due to their high price tags and limited long-term data. Developing financial assistance programs and exploring alternative funding models are important. Increased clinical data and evidence of cost-effectiveness can improve coverage.

Gene Therapy 71

Gene Therapy Manufacturing Gene Clinical Trials 71

Delveinsight

FEBRUARY 23, 2021

The company plans to use the capital to expand its pipeline of protein-based vaccines and biologic cancer therapies utilizing its innovative and proprietary Trimer-Tag technology platform. The company develops transformative biologics including vaccines and therapeutics for the world’s most debilitating diseases.

In-Vitro 52

In-Vitro Vaccination Vaccine Licensing 52

pharmaphorum

AUGUST 28, 2020

Established with funding from the National Library of Medicine (NLM), it pulls data from sources including news stories, blogs, social media, and chat rooms. “We We are ingesting hundreds of thousands of pieces of information daily and we tag that information across locations, disease types, species, and case counts.

Medicine 72

Medicine Research 72

Rethinking Clinical Trials

JANUARY 23, 2024

Discussion Themes -Why aren’t payors more willing to fund these trials? I have not seen a payor fund a trial in this space. Tags #pctGR, @Collaboratory1 The post Grand Rounds January 19, 2024: Why Are Imaging RCTs Different? Process of care/efficiency measures are important. There has only been a hand full of trials.

Trials 152

Trials Cardiology Clinical Trials Clinical Trials 152

XTalks

FEBRUARY 27, 2024

Despite high price tags of a couple of million dollars, gene therapy makers say they are working to ensure patients are able to access the treatments through patient assistance programs developed in conjunction with the support of governments. Sarepta hopes to clarify Elvidys’ effectiveness in older children in a confirmatory trial.

Research 59

Research Drugs Gene Therapy Clinical Trials 59

The Pharma Data

NOVEMBER 15, 2020

Peng Liang , Founder and Chief Scientific Officer of Clover and inventor of the Trimer-Tag© technology, says, “A successful vaccine that can truly modulate the course of the COVID-19 pandemic must have four essential characteristics: safety, efficacy, scalability of manufacturing, and speed.

Vaccination 52

Vaccination Vaccine Manufacturing Life Science 52

XTalks

DECEMBER 21, 2022

Despite the two blockbuster gene therapy approvals, the company sold one of its two priority review vouchers to Argenx SE for $102 million in November to raise some much-needed funds. And almost every time a new gene therapy approval was awarded, it would more often than not break the previous ‘world’s most expensive drug’ record.

Life Science 52

Life Science Gene Therapy Gene Clinical Trials 52

STAT News

MARCH 9, 2023

WASHINGTON — The Biden administration is calling on Congress to fund a more than $11 billion program to eliminate hepatitis C in the United States. billion.

Drugs 116

Drugs 116

XTalks

FEBRUARY 11, 2021

They conducted two experiments, one with radioactive phosphorous to label DNA, and one with radioactive sulfur to tag protein (DNA does not contain sulfur and protein does not contain phosphate groups). She also established a scholarship fund at Queens College for African Americans in commemoration of her father in 1988.

Genetics 119

Genetics DNA Genome Genomics 119

The Pharma Data

MAY 5, 2021

Day One pivots to an IPO for more funding to back its work in pediatric cancer ( Endpoints ). AbbVie’s Humira regains top pharma TV spender spot, while sibling brands Rinvoq and Skyrizi tag along ( Fierce ). . FDA approves 100th monoclonal antibody product ( Nature Reviews Drug Discovery ).

Vaccination 52

Vaccination Vaccine Gene Therapy Contract Packaging 52

The Pharma Data

MAY 4, 2021

healthcare reform or legislation or any significant spending reductions or cost controls affecting Medicare, Medicaid or other publicly funded or subsidized health programs or changes in the tax treatment of employer-sponsored health insurance that may be implemented; U.S. View source version on businesswire.com : [link]. Source: Pfizer Inc.

Vaccination 40

Vaccination Vaccine Production Sales 40

XTalks

FEBRUARY 14, 2023

Although nutrition programs are funded through regular budget bills, the Farm Bill helps make the rules for how the programs will work and who qualifies. Spending on the nutrition title alone is expected to push the price tag for the next Farm Bill to more than $1 trillion over the next ten years.

Packaging 98

Packaging Packaging Production Marketing 98

World of DTC Marketing

JUNE 16, 2021

The pharma industry has been riding a wave of public approval since they developed a vaccine to fight COVID-19, but that goodwill is going to be short lived thanks, in part, to the $56,000 price tag of Biogen’s new drug and insulin that too many people still can’t afford.

Drugs 180

Drugs Branding Medicine Insulin 180

Pharmacy Checkers

JANUARY 30, 2020

Tagged the “pharma bro” for the cavalier attitude he fronted about his greed, Martin is actually currently behind bars. No, not for raising a drug price – otherwise the jails would overflow with pharma execs – but for financial fraud related to his work as hedge fund manager. That’s old news.

Drugs 54

Drugs Generic Drugs Cosmetics FDA Approval 54