Rethinking Clinical Trials

JANUARY 26, 2023

This study is looking at a particular subpopulation, where there is a lack of outcomes data. EVOLVE-MI is a pragmatic, effectiveness outcome trial of Evolocumab dosed within 10 days of a myocardial infarction (MI). EVOLVE-MI is a pragmatic, effectiveness outcome trial of Evolocumab dosed within 10 days of a myocardial infarction (MI).

Trials 130

Trials Clinical Trials Clinical Trials Medicine 130

Rethinking Clinical Trials

MARCH 6, 2024

Payers should have some incentive to improve outcomes because sustained reduction in HbA1c from poor to fair can result in cost savings. Food-as-Medicine observational studies have had a large correlation with improved health. The primary outcome was HbA1c after 6 months. 9% of the U.S. HbA1c it dropped to a mean of 8.8

Clinical Trials 141

Clinical Trials Clinical Trials Medicine Trials 141

Rethinking Clinical Trials

JULY 19, 2023

The objective of COORDINATE-Diabetes trial was to improve the implementation and adoption of these therapies by testing the impact of a clinic-level, multifaceted intervention on the prescription of 3 key groups of evidence-based therapies. of the patients ended up being prescribed all 3 therapies, and 37.9%

Trials 130

Trials Cardiology Medicine Nurses 130

World of DTC Marketing

JUNE 23, 2021

SKIMMERS SUMMARY: Jefferies analysts found doctors have shown strong interest in prescribing Aduhelm for about 35% of early-stage Alzheimer’s patients with mild cognitive impairment after surveying 50 U.S. neurologists or psychiatrists currently treating about 12,000 Alzheimer’s patients. Not to mention the $56,000 annual price tag.

Drugs 218

Drugs FDA Approval Doctors Doctor 218

Rethinking Clinical Trials

MARCH 28, 2023

                                           Speakers Erin Holve, PhD, MPH, MPP Chief Research Infrastructure Officer, Patient-Centered Outcomes Research Institute (PCORI) Russell Rothman. Patients and caregivers are integrated into all phases of PCORnet®.-enabled enabled research.

Clinical Trials 130

Clinical Trials Clinical Trials Trials Research 130

Rethinking Clinical Trials

SEPTEMBER 28, 2023

Donabedian’s Quality Framework includes a structure that supports care, a process for the provision and receipt of care, and health outcomes, providing a process without a structure to support it. Integrating a community health care workers into the well child care team improves well child care for Medicaid-insured children.

Trials 269

Trials Clinical Trials Clinical Trials Research 269

Rethinking Clinical Trials

JULY 27, 2022

It is a decentralized, fully remote trial, and data are largely patient reported. Participants test positive for COVID-19 with a FDA-authorized test, register from home, are randomized remotely, receive study medication through the central pharmacy, and follow instruction until their clinical symptoms improve. Learn more about ACTIV-6.

Trials 169

Trials Pharmacy Medicine Clinical Trials 169

pharmaphorum

OCTOBER 18, 2022

Medtech giant Beckton Dickinson (BD) has signed a deal with France’s Biocorp to use the latter’s near-field communication (NFC) tags in injectable devices. The Injay tag can confirm a complete injection and transfer that information via an NFC reader to a smartphone or tablet for review by a healthcare professional.

Drug Delivery 52

Drug Delivery Manufacturing Drugs Marketing 52

Rethinking Clinical Trials

APRIL 13, 2023

It works to improve health care value and outcomes, advance the science of designing interventions to change behavior and evaluate and disseminate the impact of interventions. Launched in 2016, the Penn Medicine Nudge Unit is the world’s first behavioral design team embedded within a health system.

Medicine 100

Medicine Trials Cardiology Development 100

Rethinking Clinical Trials

MARCH 1, 2023

S1800A was a Phase II randomized study of ramucirumab plus pembrolizumab versus standard of care for NSCLC patients previously treated with immunotherapy performed within the Lung-MAP platform. Overall survival was significantly improved with a hazard ratio of 0.69, median OS of 14.5 verses other immunotherapeutic agents)?

Clinical Trials 130

Clinical Trials Clinical Trials Trials Packaging 130

Rethinking Clinical Trials

DECEMBER 6, 2022

This study asks how can we better facilitate health behaviors in patients with chronic diseases and can we leverage technology? that focused on patients with heart failure and diabetes, two rapidly growing conditions that are highly morbid. Patients did not get text messages about pill adherence.

Trials 130

Trials Clinical Trials Clinical Trials Compliance 130

Roots Analysis

JANUARY 28, 2024

Not only in healthcare, but various industries have also adopted big data to enhance their capabilities, improve customer experiences, and strengthen their brand reputation, thereby contributing to overall growth of the company. It is loosely arranged into categories using meta tags.

Big Data 40

Big Data Medicine Marketing Clinical Trials 40

Intouch Solutions

APRIL 11, 2024

It has continually evolved, embracing new technologies and methodologies to improve drug discovery, development, and distribution. Pre-Clinical : Deeper comprehension of the impacts and outcomes associated with a particular drug. Manufacturing : Improved operations, efficiency, and production costs.

Compliance 52

Compliance Marketing Drugs Pharma Companies 52

Rethinking Clinical Trials

SEPTEMBER 16, 2022

How are patients and families included in governance of learning within your LHS? One challenge is that academic medical institutions traditionally have multiple missions, including research, patient care, and education, and systemically integrating learning into clinical operations is novel addition to the traditional missions.

Clinical Trials 100

Clinical Trials Clinical Trials Trials Research 100

XTalks

JUNE 28, 2023

Elevidys was granted FDA accelerated approval for the treatment of pediatric patients four to five years of age with DMD who have a confirmed mutation in the DMD gene. It is indicated for patients who do not have a pre-existing medical reason preventing treatment with the therapy. million price tag of Elevidys, a one-time gene therapy.

Gene Therapy 98

Gene Therapy Gene Protein FDA Approval 98

pharmaphorum

DECEMBER 23, 2021

The designation – which is awarded to therapies that could represent a significant improvement over standard of care in either efficacy, safety, or both – has been awarded on the strength of phase 1 results in patients with metastatic or locally advanced EGFR-mutated non-small cell lung cancer (NSCLC).

Drugs 71

Drugs Antibody Clinical Trials Clinical Trials 71

pharmaphorum

JANUARY 31, 2023

This lack of trust in such a crucial industry can lead to decreased compliance, poor treatment adherence, and negative health outcomes for patients. Additionally, when patients are prescribed medication, they are often unaware of the mechanism of action, potential side effects, interactions, and contraindications.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Vaccination 52

pharmaphorum

JUNE 12, 2022

The panel voted 13 to 0 on the question of whether beti-cel’s benefits outweighed the risks of the gene therapy in patients with beta thalassaemia who are dependent on blood transfusions, in a dream result for the biotech which just a few weeks ago was expressing doubts about its ability to continue as an operating concern.

Gene Therapy 58

Gene Therapy Gene Marketing Trials 58

The Pharma Data

NOVEMBER 29, 2021

1.1.529 a variant of concern, named Omicron, on the advice of WHO’s Technical Advisory Group on Virus Evolution (TAG-VE). Effectiveness of current treatments : Corticosteroids and IL6 Receptor Blockers will still be effective for managing patients with severe COVID-19. On 26 November 2021, WHO designated the variant B.1.1.529

Vaccination 52

Vaccination Vaccine Genome Genomics 52

XTalks

DECEMBER 21, 2022

This included greater adoption and acceptance of decentralized clinical trial models, emphasis on patient-centric approaches in trials, growing digitization of healthcare and dealing with drug manufacturing challenges. Gene Therapy Approvals. Manufacturer: Ferring Pharmaceuticals A/S. Manufacturer: bluebird bio, Inc.

Life Science 52

Life Science Gene Therapy Gene Clinical Trials 52

XTalks

JUNE 8, 2021

Novartis’ Zolgensma (onasemnogene abeparvovec) gene therapy has been making significant strides as of late, including dosing of the first Spinal Muscular Atrophy (SMA) patient with the treatment in the UK last week. Prior to Zolgensma, treatments could only help manage symptoms and attempt to improve quality of life.

Gene Therapy 110

Gene Therapy Gene Protein Trials 110

pharmaphorum

SEPTEMBER 15, 2020

The huge rise in the use of telemedicine services during lockdown has brought care directly to patients in their homes, while pharma’s communications with healthcare professionals (HCPs) has experienced a similar push to digital channels. Jeremy Richter, Tag. We’re all trying to find ways to automate. About the interviewees.

Branding 128

Branding Marketing Pharma Companies Life Science 128

XTalks

FEBRUARY 27, 2024

Skyclarys (omobaloxone) was approved in 2023 for the treatment of adults and pediatric patients 16 years of age and older with Friedreich’s ataxia, a rare, neurological disease​​. Sarepta hopes to clarify Elvidys’ effectiveness in older children in a confirmatory trial.

Research 59

Research Drugs Gene Therapy Clinical Trials 59

pharmaphorum

AUGUST 17, 2020

In this article Joanna Carlish, managing director of financial services at Tag Americas , and Robb DeFilippis, Tag Americas’ managing director, life sciences, go head-to-head to discuss marketing within a regulated industry. Virtual connections. Engagement channels. Regulated industry learnings.

Regulation 97

Regulation Marketing Sales Branding 97

pharmaphorum

OCTOBER 29, 2021

Trodelvy has already established itself as a go-to therapy for TNBC patients whose disease has progressed after prior treatments, says Gilead, while Keytruda is approved as a first-line therapy for the cancer in combination with chemotherapy, in patients with PD-L1 scores of 10 or more. While its headline revenue of $7.4

Trials 52

Trials Sales FDA Approval Production 52

pharmaphorum

JANUARY 5, 2021

The FDA’s breakthrough status is for tiragolumab plus Tecentriq is the first for a TIGIT drug, and covers the first-line treatment of patients with advanced-stage non-small cell lung cancer (NSCLC) that expresses high levels of PD-L1. The post Roche nabs breakthrough tag for TIGIT cancer immunotherapy appeared first on.

Immune Response 52

Immune Response FDA Approval Drugs Sales 52

pharmaphorum

JUNE 2, 2021

NICE has rejected routine NHS funding for Roche’s Evrysdi (risdiplam) for spinal muscular atrophy drug in draft guidance, a decision which doesn’t come as a surprise to patient association SMA UK. The post NICE ‘no’ to Roche’s risdiplam for SMA not unexpected, says patient group appeared first on.

Gene Therapy 52

Gene Therapy Gene Drugs Medicine 52

Delveinsight

FEBRUARY 23, 2021

The company plans to use the capital to expand its pipeline of protein-based vaccines and biologic cancer therapies utilizing its innovative and proprietary Trimer-Tag technology platform. Despite the feedback, the platform showed improvements in some ALS patients, and it presents a positive picture.

In-Vitro 52

In-Vitro Vaccination Vaccine Licensing 52

Delveinsight

FEBRUARY 25, 2021

Quest runs 2,200 patient service centers and recruits 5,000 mobile phlebotomists who have experience and expertise in offering phlebotomy services for at-home visits. Working with Quest will help them support convenient access to blood collection for patients and healthcare providers.

DNA 52

DNA In-Vivo Genetics Medicine 52

XTalks

JANUARY 19, 2024

Importantly, Dr. Guarnaschelli explained that it isn’t only the cell nucleus that plays a role in the cancer cell outcome as after irradiation, many other complex cell mechanisms are impacted and involved. Reoxygenation improves the efficacy of radiation therapy over multiple sessions.

DNA 66

DNA Radiology FDA Approval Development 66

XTalks

OCTOBER 12, 2022

MRI may also be used to evaluate drug dosing regimens, to gain insight about the mechanism of drug action, and to collect imaging biomarker data which could provide an earlier indication of response to therapy than clinical outcomes. Each patient is represented as one data point. Figure from Liu et al., Figure from Ricart et al.,

Clinical Trials 93

Clinical Trials Clinical Trials Trials Drugs 93

Delveinsight

JULY 22, 2020

Today the tech-based healthcare industry is providing many unique solutions to the patient’s care which are more efficient and effective than the traditional services. IoT relies on the data collected from devices and provides valuable insights that help in providing the best possible healthcare solution to the patient.

Doctors 59

Doctors Doctor Marketing Production 59

XTalks

AUGUST 23, 2021

Dr. Weninger’s fellow panel members echoed that sentiment and sought to address some of the most pressing concerns around trial design, patient safety and data integrity in trials in this post-approval period for aducanumab. Now that [aducanumab] is approved, how will this affect clinical trials going forward?”.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Drugs 52

Delveinsight

DECEMBER 3, 2020

The agreement is for the investigational phase 1 gene therapy HMR59 that is given as a one-and-done shot into the eye to preserve vision in patients with geographic atrophy , which is a late-stage and severe form of age-related macular degeneration (AMD). It has already succeeded in a phase 1 test, with a second in patients with wet AMD.

Gene Therapy 52

Gene Therapy Gene Antibody Research 52

pharmaphorum

JUNE 15, 2021

The adoption of New Science – a unique combination of the best in science and health technology that address significant unmet patient needs – is delivering more precise and effective treatments, but often at a higher price tag, according to new research. New Science is more important than ever. So we know change is not impossible.

Clinical Trials 90

Clinical Trials Clinical Trials Development Marketing 90

pharmaphorum

OCTOBER 4, 2022

The Moonshot was started with three aims: to accelerate scientific discovery in cancer, foster greater collaboration between stakeholders, and to improve the sharing of cancer data. The objective is to gather patient biospecimens longitudinally to understand how patients react to treatments and how cancer develops over time.

Biobanking 105

Biobanking Clinical Trials Clinical Trials Trials 105

The Pharma Data

MAY 4, 2021

Each of these accomplishments further demonstrates our commitment to Pfizer’s purpose: Breakthroughs that change patients’ lives.”. I remain confident in Pfizer’s ability to continue to deliver on our commitments to our patients and shareholders in 2021 and beyond.”. This will make 2021 the 12th year in a row with a dividend increase.

Vaccination 40

Vaccination Vaccine Production Sales 40