Rethinking Clinical Trials

MAY 25, 2023

Secondary safety outcomes were bleeding events, wound complications, and surgical site infections. Tags #pctGR, @Collaboratory1 The post Grand Rounds May 19, 2023: Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis After a Fracture (Robert O’Toole, MD) appeared first on Rethinking Clinical Trials.

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Rethinking Clinical Trials

FEBRUARY 20, 2024

The MINT trial investigators looked at 30-day mortality and several outcomes including MI, heart failure, stroke, bleeding, infection, and clot. Tags #pctGR, @Collaboratory1 The post Grand Rounds February 16, 2024: Clinical Implications of the MINT Trial: p=0.07 (Jeffrey Carson, MD, MACP) appeared first on Rethinking Clinical Trials.

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The Pharma Data

JANUARY 31, 2021

Utilizing Clover’s proprietary Trimer-Tag© technology, S-Trimer is a trimeric SARS-CoV-2 spike (S)-protein subunit vaccine candidate. About Trimer-Tag© Technology. Trimer-Tag© is an innovative drug development platform which allows the production of novel, covalently-trimerized fusion proteins. —- End —-.

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The Pharma Data

DECEMBER 3, 2020

We are encouraged by the high level of neutralizing antibodies in combination with the strong Th1 response which we believe could play an important role in controlling infection. Utilizing Clover’s proprietary Trimer-Tag © technology, S-Trimer is a trimeric SARS-CoV-2 spike (S)-protein subunit vaccine candidate.

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XTalks

MAY 2, 2024

Sam Davidson, Director of Food Safety at The Acheson Group (TAG) , also emphasized the need for fundamental training for frontline workers in the food industry. He underscored the evolution of infrared (IR) technology, which has significantly Xtalks speaking with JP Perreault.

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Pharmaceutical Technology

MAY 15, 2023

Innovation S-curve for the pharmaceutical industry Peptide nano-particle conjugates is a key innovation area in the pharmaceutical industry By tagging peptides with nanoparticles, peptide nano-particle conjugates allow enhanced control over their biological behaviour, overcoming intrinsic limitations of the individual materials.

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pharmaphorum

MAY 17, 2021

C5 inhibitor Soliris – which has a list price in the US of more than $500,000 per year – has been a standard therapy for the rare disorder since 2007, and was joined on the market by longer-acting follow-up Ultomiris in 2018 which launched with a price tag of around $450,000 per year. billion and $1.1

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XTalks

DECEMBER 13, 2023

It can also make patients more susceptible to complications like anemia, jaundice, infections and gallstones. Current treatments for sickle cell disease include blood transfusions but patients often have episodes of intense pain and an increased risk of stroke. Vertex-CRISPR’s Casgevy has a US list price of $2.2

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The Pharma Data

JANUARY 31, 2021

Utilizing Clover’s proprietary Trimer-Tag© technology, S-Trimer is a trimeric SARS-CoV-2 spike (S)-protein subunit vaccine candidate. About Trimer-Tag© Technology. Trimer-Tag© is an innovative drug development platform which allows the production of novel, covalently-trimerized fusion proteins.

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Pharmaceutical Technology

APRIL 5, 2023

But access to these treatments continues to remain limited due to high price tags and variable availability across regions. Currently, all approved CAR-T therapies are autologous, where T cells taken from patients are modified and then re-infused.

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The Pharma Data

OCTOBER 21, 2020

Aggressive chemo can substantially lower blood cell counts, which may leave patients vulnerable to infections or in need of multiple blood transfusions, explained Dr. Jae Park. Six patients developed an infection with cytomegalovirus (a herpes virus), and four had a drop in white blood cells. It’s too soon to say this is a cure.”

Drugs 52

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The Pharma Data

OCTOBER 21, 2020

Aggressive chemo can substantially lower blood cell counts, which may leave patients vulnerable to infections or in need of multiple blood transfusions, explained Dr. Jae Park. Six patients developed an infection with cytomegalovirus (a herpes virus), and four had a drop in white blood cells. It’s too soon to say this is a cure.”

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Drugs Genetics Trials Research 52

Druggist

OCTOBER 25, 2020

Calamine lotion for chickenpox is usually considered the first choice in the management of itchiness caused by varicella-zoster virus infection. Chickenpox is a common viral infection, which usually affects children; however, it may also affect adults. In the final part of the infection, blisters scab over, forming crusted spots.

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XTalks

FEBRUARY 27, 2024

Addressing the high price tag, Iovance’s commercial chief Jim Ziegler said, “Payers have expressed their appreciation for the value proposition for Amtagvi.” Among some of the concerns around Amtagvi are a boxed warning for treatment-related deaths, prolonged severe cytopenia, severe infection and cardiopulmonary and kidney impairment.

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Drug Discovery World

OCTOBER 28, 2022

‘Click’ chemistry used to tag proteins made by cancer cells . Experimental monoclonal antibodies block EBV infection . A panel of investigational monoclonal antibodies (mAbs) targeting different sites of the Epstein-Barr virus (EBV) have been shown to block infection when tested in human cells in a laboratory setting. . .

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Drugs Antibody Protein RNA 52

The Pharma Data

NOVEMBER 15, 2020

Peng Liang , Founder and Chief Scientific Officer of Clover and inventor of the Trimer-Tag© technology, says, “A successful vaccine that can truly modulate the course of the COVID-19 pandemic must have four essential characteristics: safety, efficacy, scalability of manufacturing, and speed. .”

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The Pharma Data

APRIL 22, 2023

Many antibodies used to treat covid infection during the pandemic have been so-called neutralizing antibodies that prevent the virus from infecting the cell. But as the virus has mutated, the ability of these antibodies to bind to the virus has been lost, and thus also their protective effect.

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XTalks

NOVEMBER 27, 2021

The technical advisory group on SARS-CoV-2 virus evolution (TAG-VE) met on Friday to discuss B.1.1.529, Infections have been rising sharply in the country in recent weeks. So far there are 77 confirmed cases of infections due to Omicron. 1.1.529, two days after it was first reported to the global health agency by South Africa.

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XTalks

AUGUST 17, 2020

T cell transfer or adoptive/immune cell therapy : these enhance the natural ability of T cells to fight infection, cancer or other disease processes. Immune checkpoint inhibitors : these are drugs that block immune checkpoints, allowing immune cells to elicit enhanced responses to cancer cells.

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Delveinsight

DECEMBER 3, 2020

The company anticipates the test can aid in tracking the success of vaccines and recognize people who have recovered from infection and could serve as convalescent plasma donors or help in the development of new therapies. of the time and negative results 99.98% of the time, as per Roche. Janssen buys a gene therapy asset.

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Gene Therapy Gene Antibody Research 52

XTalks

FEBRUARY 11, 2021

In the experiments, Hershey and Chase infected bacteria with radioactively labeled bacteriophages (viruses that specifically infect bacteria), which consist of both DNA and protein. Charpentier has served as a director at the Max Planck Institute for Infection Biology in Berlin since 2015.

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XTalks

MARCH 22, 2023

In addition, nearly half of all new drugs launched between 2020 and 2021 came with a price tag of $150,000 per year, or more. Increased competition from generics and biosimilars has also prompted widespread change within the industry.

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XTalks

JANUARY 19, 2024

This biological variability adds complexity, but with that complexity comes the power to choose the targets, the tags and the payloads and select combinations appropriate to the patient to personalize that therapy. There is also potential for using several radiotherapies in combination therapies. References The Green Journal.

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The Pharma Data

MAY 4, 2021

These assumptions are guided by the trajectory of current infection rates in many parts of the world and the expected timeline for broad access to effective vaccines. Amplyx’s lead compound, Fosmanogepix (APX001), is a novel investigational asset in Phase 2 development for the treatment of invasive fungal infections. Source link.

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