Rethinking Clinical Trials

OCTOBER 26, 2023

Untreated, chronic Hepatitis C infection leads to liver damage, liver cancer, and death. Tags #pctGR, @Collaboratory1 The post Grand Rounds October 20, 2023: A National Initiative to Eliminate Hepatitis C in the United States – Why This Matters to Clinical Trialists (Rachael L.

Clinical Research 141

Clinical Research Clinical Trials Clinical Trials Research 141

Drug Discovery World

JANUARY 9, 2023

In this early research, Khalid Shah, Professor of Neurosurgery at Harvard Medical School and Brigham and Women’s Hospital, and colleagues tested the vaccine in an advanced mouse model of brain cancer glioblastoma, with promising results. The findings are published in Science Translational Medicine. . CRISPR-Cas9 gene editing .

Scientist 52

Scientist Gene Editing Gene Engineer 52

pharmaphorum

FEBRUARY 22, 2021

Bluebird Bio’s decision to hit pause on the launch of Zynteglo for beta thalassaemia after two cases of cancer were seen in a clinical trial could see fears over the safety of viral vectors used to deliver gene therapies resurface. . million in Europe.

Gene Therapy 52

Gene Therapy Gene Gene Sequencing Gene Expression 52

XTalks

JANUARY 28, 2022

Up to 50 percent of patients will develop metastatic disease, mainly spreading to the liver, making treatment difficult and limited. Kimmtrak has a price tag of $18,760 per vial, which amounts to a weekly dose. Related: Cancer Blood Test Developed by University of Oxford Researchers Can Detect Metastasis.

FDA Approval 98

FDA Approval Development Licensing Licensing 98

XTalks

OCTOBER 26, 2021

The treatment came with an initial price tag of $39,000 per vial, which amounts to a total of $575,00 each year. A lack of the gene leads to accumulation of porphyrins — essential compounds found in hemoglobin — in the liver. However, Alnylam recently offered a confidential discount just before NICE’s latest recommendation came out.

Gene Silencing 98

Gene Silencing Gene Clinical Trials Clinical Trials 98

Delveinsight

FEBRUARY 25, 2021

The company’s in vivo therapies reach the eye and central nervous system via adeno-associated viruses, while its liver therapies employ lipid nanoparticles (LNPs). GRAIL and Quest collaborate for the cancer blood test. Overall, this could result in a 26% overall reduction in all five-year cancer deaths.

DNA 52

DNA In-Vivo Genetics Medicine 52

XTalks

OCTOBER 12, 2022

Features of blood perfusion in the brain detected by MRI now have clinical applications in central nervous system (CNS) cancers, neurodegenerative disease, cerebrovascular disease and demyelinating disease. The other option is to tag just one of the feeder vessels to the liver, but that does not capture the full blood flow in the liver.”.

Clinical Trials 93

Clinical Trials Clinical Trials Trials Drugs 93