Pharmaceutical Technology

JULY 14, 2022

Due to the high price tags associated with these speciality medicines, innovators have naturally favoured big markets with high GDP such as the US and EU-5 (Germany, France, Spain, Italy, and the UK). Go-to-market strategies. The choice of where to launch an orphan drug is an important and difficult decision.

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Rethinking Clinical Trials

MARCH 6, 2024

Schell Professor of Management and Applied Economics MIT Sloan School of Management Slides Keywords Food-as-Medicine, Randomized Clinical Trial, Diabetes Key Points Diabetes is common and costly. Food-as-Medicine observational studies have had a large correlation with improved health. 9% of the U.S.

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Scienmag

APRIL 29, 2021

Credit: UC San Diego Health Sciences Researchers at University of California San Diego School of Medicine have discovered one way in which SARS-CoV-2, the coronavirus that causes COVID-19, hijacks human cell machinery to blunt the immune response, allowing it to establish infection, replicate and cause disease.

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Pharmaceutical Technology

NOVEMBER 9, 2022

million price tag. But the justification for Roctavian’s cost will depend on positive responses to the treatment, says Dr. Guy Young, professor of pediatrics at University of Southern California’s Keck School of Medicine. The post Can gene therapies for haemophilia defend their high price tags? million ($1.8

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Rethinking Clinical Trials

SEPTEMBER 13, 2023

Learn more Read more in the New England Journal of Medicine. Tags #pctGR, @Collaboratory1 The post Grand Rounds September 8, 2023: The DEVICE Trial: An Embedded, Pragmatic Trial of Emergency Airway Management (Matthew Prekker, MD, MPH; Jonathan Casey, MD, MSc) appeared first on Rethinking Clinical Trials.

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Rethinking Clinical Trials

NOVEMBER 1, 2022

Duke University School of Medicine. Director, Vanderbilt Institute for Medicine and Public Health. Emily O’Brien, PhD, FAHA. Associate Professor. Duke Clinical Research Institute. Department of Population Health Sciences. Russell Rothman, MD, MPP. Senior Vice President, Population and Public Health. pctGR, @Collaboratory1.

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Rethinking Clinical Trials

DECEMBER 12, 2023

Tags #pctGR, @Collaboratory1 The post Grand Rounds December 8, 2023: A Pragmatic Randomized Trial of the Jumpstart Intervention to Promote Communication about Goals of Care for Hospitalized Patients with Serious Illness (Ruth Engelberg, PhD; Erin Kross, MD; Robert Lee, MD, MS) appeared first on Rethinking Clinical Trials.

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Pharmaceutical Technology

FEBRUARY 10, 2023

This is not the first treatment to come with a high price tag. Access to oncology medicines varies across countries, and their cost against safety/efficacy is generally perceived as being low, such as in the US. million, according to GlobalData’s Price Intelligence (POLI), making it the most expensive drug in the world.

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Pharma Tutor

NOVEMBER 19, 2021

We have exported life-saving medicines and medical equipment to over 150 countries during the initial phase of the pandemic. He said that our definition of wellness is not limited by physical boundaries. We have also exported more than 65 million doses of COVID vaccines to nearly 100 countries this year. Fri, 11/19/2021 - 16:19. Pharmapedia.

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Rethinking Clinical Trials

JULY 22, 2022

Read more in Annals of Internal Medicine and Critical Care Medicine. View the Summary of NIH-Funded ACTIV/ACTIV-Associated Clinical Trials. pctGR, @Collaboratory1.

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pharmaphorum

OCTOBER 18, 2022

Medtech giant Beckton Dickinson (BD) has signed a deal with France’s Biocorp to use the latter’s near-field communication (NFC) tags in injectable devices. The Injay tag can confirm a complete injection and transfer that information via an NFC reader to a smartphone or tablet for review by a healthcare professional.

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World of DTC Marketing

SEPTEMBER 24, 2021

This drug was never about patients; it was about a company whose ego got too big and needed a savior in the form of a medicine that could bring in hundreds of millions of dollars. Physicians and insurers are rejecting Aduhelm because it should never have been approved in the first place.

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Rethinking Clinical Trials

AUGUST 3, 2023

Bergstrom, PhD Professor, Department of Biology University of Washington Slides Keywords Research, Misinformation, Media, Social Media Key Points Misinformation abounds in medicine and about medicine. Tags #pctGR, @Collaboratory1 The post Grand Rounds July 28, 2023: How Can Researchers Fight Misinformation About Medicine?

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Rethinking Clinical Trials

AUGUST 23, 2022

Associate Professor with Tenure, Medicine. Duke University School of Medicine. Assistant Professor of Medicine. Duke University School of Medicine. ? ? ? ? ? ? ? ? ? ?. Speakers. Gerald Bloomfield, MD, MPH. Associate Professor, Global Health. Michelle Kelsey, MD. Diversity, Inclusion. Key Points. Learn more.

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Rethinking Clinical Trials

OCTOBER 4, 2022

Director of Institute for Translational Medicine. Senior Director Clinical Trial Operations. Neurological Clinical Research Institute. Massachusetts General Hospital. Jörg Goldhahn, MD. Medical Director. ETH Zurich. Key Points. Tech support at the site level is important to addressing problems in a study. pctGR, @Collaboratory1.

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Rethinking Clinical Trials

MAY 19, 2023

Colwill Professor and Vice Chair Department of Family and Community Medicine University of Missouri Slides Keywords Electronic Health Record, Pragmatic Clinical Trial Key Points Patients bring patient-generated home blood pressure data into the clinical workflow. Koopman, MD, MS Jack M. and Winifred S.

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Rethinking Clinical Trials

JULY 27, 2022

Professor of Medicine. Duke University School of Medicine. ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?. Speaker. Susanna Naggie, MD, MHS. Vice Dean for Clinical Research. ACTIV, ACTIV-6, COVID-19, Ivermectin, Inhaled Fluticasone. Key Points. Learn more about ACTIV-6. pctGR, @Collaboratory1.

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Rethinking Clinical Trials

AUGUST 22, 2022

Assistant Professor, General Internal Medicine and Pediatrics. Core Faculty, Center for Pediatric Obesity Medicine. ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?. Speakers. Carolyn Bramante, MD, MPH. Core Faculty, Program for Health Disparities Research. University of Minnesota Medical School. Thomas Murray, PhD.

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Rethinking Clinical Trials

OCTOBER 2, 2023

With current funding, PROTEUS can address recommendations specifically regarding education materials. We are pursuing funding.

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Rethinking Clinical Trials

APRIL 18, 2023

Tags #pctGR, @Collaboratory1 The post Grand Rounds April 14, 2023: RECOVER in Action – Status of Clinical Trial Protocols (Kanecia Zimmerman, PhD, MD, MPH) appeared first on Rethinking Clinical Trials. It seems the most severely affected people came from the early waves of COVID.

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Rethinking Clinical Trials

FEBRUARY 16, 2023

Tags #pctGR, @Collaboratory1 The post Grand Rounds Ethics and Regulatory Series February 10, 2023: Informing and Consenting: What Are the Goals? (P. For NUDGE, there was the initial letter where patients could opt-out by sending a postcard and they could also opt-out in response to the text messages. Pearl O’Rourke, MD; David S.

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Rethinking Clinical Trials

JANUARY 9, 2024

Tags #pctGR, @Collaboratory1 The post Grand Rounds Biostatistics Series January 5, 2024: Methods for Handling Missing Data in Cluster Randomized Trials (Rui Wang, PhD; Moderator: Fan Li, PhD) appeared first on Rethinking Clinical Trials. At the end, we just need a model for predicting the probability of the observed.

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Rethinking Clinical Trials

FEBRUARY 28, 2024

            Speakers Adrian Hernandez, MD Executive Director, Duke Clinical Research Institute Vice Dean, Duke University School of Medicine Christopher J. Tags #pctGR, @Collaboratory1 The post Grand Rounds February 23, 2024: Virtual Vigilance: Monitoring of Decentralized Clinical Trials (Adrian Hernandez, MD; Christopher J.

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Rethinking Clinical Trials

DECEMBER 14, 2022

Full Professor, Epidemiology and Community Medicine. Raffin Professor of Medicine and Biomedical Ethics and Professor of Pediatrics, Medicine, and by courtesy of Bioengineering. Senior Scientist, Clinical Epidemiology Program. Ottawa Hospital Research Institute. University of Ottawa. David Magnus, PhD. pctGR, @Collaboratory1.

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pharmaphorum

NOVEMBER 16, 2021

The cost-effectiveness agency has backed Ontozry (cenobamate) as an option for treating focal onset seizures with or without secondary generalised seizures in adults with drug-resistant epilepsy that has not been adequately controlled with at least two prior antiseizure medicines.

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Rethinking Clinical Trials

MARCH 28, 2023

Tags #pctGR, @Collaboratory1 The post Grand Rounds March 24, 2023: From Observational Studies to Pragmatic Clinical Trials: (Almost) A Decade of Research in PCORnet® (Erin Holve, PhD, MPH, MPP; Russell Rothman, MD, MPP; Schuyler Jones, MD; Neha Pagidipati, MD, MPH) appeared first on Rethinking Clinical Trials.

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pharmaphorum

APRIL 26, 2021

In 2019 Cognitant and Addenbrook’s Hospital in Cambridge, UK piloted a programme that aimed to educate patients to improve adherence to rheumatoid arthritis medicines. Virtual reality is a technology that is beginning to be used in healthcare across a variety of settings.

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Rethinking Clinical Trials

FEBRUARY 20, 2024

             Speaker Jeffrey Carson, MD, MACP Principal Investigator and Study Chair MINT Trial Provost-New Brunswick, Rutgers Biomedical Health Sciences Distinguished Professor of Medicine Richard C. Reynolds, M.D. In general, I think as these things go, it was quite positive.

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Drug Discovery World

DECEMBER 20, 2022

The first gene therapy for haemophilia B could soon be available to patients in Europe following a positive opinion from the Committee for Medicinal Products for Human Use (CHMP). . Concerns about the high price tag have been raised in an article in Nature, particularly whether it will be affordable for low to middle-income countries. .

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Rethinking Clinical Trials

JANUARY 31, 2024

Tags #pctGR, @Collaboratory1 The post Grand Rounds January 26, 2024: Advancing the Safe, Effective and Equitable Use of AI in Healthcare (Mark Sendak, MD, MPP; Suresh Balu, MD, MBA) appeared first on Rethinking Clinical Trials. – How do you get reliable information and data for care that is received outside of Duke?

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Rethinking Clinical Trials

MAY 10, 2023

Denny, MD, MS CEO, All of Us Research Program Slides Keywords Precision Medicine, All of Us Research Program Key Points The mission of the All of Us Research Program is to accelerate health research and medical breakthroughs, enabling individualized prevention, treatment, and care for all of us. We are looking forward to supporting more.

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Rethinking Clinical Trials

NOVEMBER 16, 2022

Associate Director, Center for Bioethics & Social Sciences in Medicine. Berman Institute of Bioethics & Johns Hopkins Bloomberg School of Public Health. Kayte Spector-Bagdady, JD, MBioethics. Assistant Professor of Obstetrics & Gynecology. University of Michigan Medical School. Ethics, Data Sharing, Pragmatic Clinical Trials.

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Rethinking Clinical Trials

APRIL 27, 2023

Am I delivering great medicine when I’m not sure what to do here when there is practice variability? In terms of the dialysis component, in routine care we get consent when we start treatment but there are many things in the background.

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Roots Analysis

MARCH 1, 2024

In order to effectively combat the problems related to counterfeit medicines, several companies have come up with innovative technologies to provide the necessary tools to manufacturers, healthcare professionals and patients to authenticate pharmaceutical products.

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pharmaphorum

JANUARY 21, 2022

Access to medicines is “one of the most challenging policy areas in every country in the European region” – it’s time to develop a solution that works for everyone. Balancing the incentivisation of innovation against affordable access to revolutionary new medicines is an age-old conundrum in the biopharmaceutical industry.

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Rethinking Clinical Trials

OCTOBER 18, 2023

Speaker Keith Marsolo, PhD Associate Professor Department of Population Health Sciences Duke University School of Medicine Slides Keywords PCORnet, Common Data Model, EHR, Social Determinants of Health Key Points There are many different definitions of social determinants of health.

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Drug Discovery World

JANUARY 9, 2023

The findings are published in Science Translational Medicine. . The engineered tumour cells were also designed to express factors that would make it easy for the immune system to spot, tag, and remember them, priming the immune system for a long-term antitumour response. .

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