Rethinking Clinical Trials

OCTOBER 2, 2023

The PROTEUS Consortium partners with key stakeholder groups to disseminate and implement tools that have been developed to optimize the use of PROs in clinical trials and practice. Over the last decade, collection of guidance documents and resources have been developed to develop each of the steps in the clinical trial directory.

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Rethinking Clinical Trials

DECEMBER 20, 2023

Globally cardiovascular disease (CVD) prevalence had decreased between 1990 and 2010, but it has slightly increased since 2010. CVD is the leading cause of mortality in women. The median survival time after a first myocardial infarction (MI) for adults 45 years and older is 8.2 years for males and 5.5 years for females at age 45 years or older.

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Rethinking Clinical Trials

FEBRUARY 28, 2024

            Speakers Adrian Hernandez, MD Executive Director, Duke Clinical Research Institute Vice Dean, Duke University School of Medicine Christopher J. The global decentralized clinical trial market is expected to grow at a compound annual growth rate of 30.1% from 2021 to 2026. Were there any major GCP-related issues?

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Rethinking Clinical Trials

FEBRUARY 14, 2024

DCP developed an EHR-based workflows and integrated workflows within the local VA primary care setting. DCP developed 3 electronic workflows with 6 major configurations including applications needed outside of the EHR system. DCP developed a patient tracking tool that nurses could use to make sure patients got through each step.

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STAT News

MARCH 10, 2023

Enjoy, and see you soon … By law, Medicare will have to take a medication’s efficacy and its research and development costs into account when it starts to negotiate drug prices — but recent research shows pharma companies ignore those factors when they pick prices for their products , STAT explains.

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Rethinking Clinical Trials

APRIL 18, 2023

RECOVER is a patient-centered, integrated, adaptive research network. RECOVER has used cohort data to identify major symptom clusters and develop 5 platform protocols that will investigator priority symptom clusters and their causes; test known and novel interventions across domains; and evaluate treatments to improve Long COVID symptoms.

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Rethinking Clinical Trials

JULY 22, 2022

Associate Vice President, Research Partnerships. ACTIV was stood up in about a month, launching on April 17, 2020, to develop a coordinated research response to speed COVID-19 treatment and vaccine options. From this review, 11 ACTIV master protocols were developed. Foundation for the NIH. ACTIV, COVID-19, FNIH.

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Rethinking Clinical Trials

NOVEMBER 16, 2022

As one of the federal departments and agencies with the largest research and development budget, the NIH came out with one of the first federal data sharing policies in 2003 called the NIH Data Sharing Policy and Implementation Guidance. Ethics, Data Sharing, Pragmatic Clinical Trials. Key Points. Discussion Themes.

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Drug Discovery World

MARCH 2, 2023

A new paper has solved the 20-year mystery of how epigenetic modifications act as traffic lights to control gene expression and could ultimately speed up the development of a new class of epigenetic cancer drugs. But, until now, scientists lacked an understanding of what the chemical tag does, despite many years of research.

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Rethinking Clinical Trials

MAY 10, 2023

Denny, MD, MS CEO, All of Us Research Program Slides Keywords Precision Medicine, All of Us Research Program Key Points The mission of the All of Us Research Program is to accelerate health research and medical breakthroughs, enabling individualized prevention, treatment, and care for all of us.

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pharmaphorum

APRIL 26, 2021

Technology firm Jolly Good and Teijin Pharma have begun a partnership to develop virtual reality digital therapeutics (VR DTx) for major depressive disorder. Jolly Good is a medical technology company that develops VR solutions and AI-based medical and welfare services that analyse user behaviour in the VR space.

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Rethinking Clinical Trials

OCTOBER 26, 2023

There are possible clinical research components that would include research on treatment during pregnancy, vaccine development, and implementation model research. A manuscript is under development. with the rate of reported acute Hepatitis C cases increasing 400% during 2010-2020.

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Rethinking Clinical Trials

JANUARY 17, 2024

Any patient admitted to the hospital with COVID-19 completed a COVID intake form in their admission record, and if they opted to learn about experimental therapies, a FaceTime call was set up with a research coordinator.          Speaker Erin K. The first drug that used the new process was Remdesivir in May 2020.

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Clinical Trials Clinical Trials Antibody Trials 169

Rethinking Clinical Trials

OCTOBER 11, 2023

The use of the term “hybrid design” is unfortunate, as it suggests that implementation research has different methods than other research and might not be held to the same standards. Instead, we should use the same rigorous methods for implementation research that we use for other research and simply change the focus.

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Intouch Solutions

NOVEMBER 30, 2021

blue links) of the organic results appeared to be pulling from content outside of the HTML title tag at a much higher frequency. URLs Examined: 860 URLs across 50 websites were examined; only URLs with all available data points were part of this research. Specifically, title links (i.e., Our Methodology.

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BioTech 365

AUGUST 21, 2020

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: Researchers create bioluminescent tag to detect DNA break repair.A

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Rethinking Clinical Trials

OCTOBER 18, 2023

The PCORnet Common Data Model (CDM) includes data available from Clinical Research Networks. Some data, such as basic clinical data and demographics, are ready for research. In 2021-2022, PCORI contracted with NORC at the University of Chicago to undertake a series of convenings to consider data infrastructure enhancements to PCORnet.

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Clinical Trials Clinical Trials Clinical Research Research 117

Pharmaceutical Technology

JULY 14, 2022

The commercial investment required to research and develop an innovative drug, prove its safety and efficacy, and bring it to market is staggering. The commercial investment required to research and develop an innovative drug, prove its safety and efficacy, and bring it to market is staggering. Go-to-market strategies.

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The Pharma Data

MAY 7, 2021

Mathai Mammen, Global Head, Research & Development Janssen Research Development will represent the Company in a session scheduled at 9:40 a.m. Remarketing tags may not be associated with personally identifiable information or placed on pages related to sensitive categories. Skip to content. Learn More.

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Drug Discovery World

OCTOBER 31, 2022

An update on the latest oncology developments by DDW Digital Content Editor Diana Spencer. Study reveals how stomach cancers develop drug resistance. Click’ chemistry used to tag proteins made by cancer cells. Click’ chemistry used to tag proteins made by cancer cells. Epigenetics vital in predicting cancer drug outcomes.

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Rethinking Clinical Trials

JULY 6, 2023

This guidance and others in development in other markets act as an important countermeasure to ensuring sustained adoption and implementation of DCTs. During the COVID-19 pandemic, several regulatory authorities around the world introduced guidance on DCTs.

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The Pharma Data

AUGUST 17, 2020

Mathai Mammen, Global Head, Research & Development Janssen Research Development will represent the Company in a session scheduled at 10:40 a.m. Remarketing tags may not be associated with personally identifiable information or placed on pages related to sensitive categories. Eastern Time).

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XTalks

FEBRUARY 27, 2024

Rare Disease Day 2024, which falls on February 29 this year, is an opportunity to unite under a common cause: to bring attention to the challenges faced by those living with rare diseases and to push for advancements in research, treatment and policy. In 2020, 31 out of 53 novel drug approvals were for rare or orphan diseases​​.

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XTalks

AUGUST 19, 2022

Along with beti-cel, there is one being developed for sickle cell (approved in Europe as Skysona or eli-cel) and another being jointly developed with Bristol Myers Squibb for melanoma. But bluebird bio has said such setbacks are expected for a company at the frontier of developing gene therapies for rare diseases.

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World of DTC Marketing

SEPTEMBER 9, 2021

If pharma is a business, they will find a way to develop, buy, or acquire new drugs. New technologies are being developed that allow for virtual clinical trials and other cost-lowering development costs. But even though the government may be saving money, ordinary taxpayers probably won’t see any discounts. healthcare.

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Rethinking Clinical Trials

AUGUST 23, 2022

The Duke Clinical Research Institute (DCRI) organized and sponsored a Think Tank to address diversity in clinical trial research. Communities should be involved from the very beginning where both the community and investigators take ownership of the research and are equally involved and interested. Discussion Themes. -Is

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Rethinking Clinical Trials

MAY 19, 2023

It is difficult to enter and create visualizations of this data in the electronic health record (EHR), so the research team developed an EHR data visualization of home blood pressure from data entered via the patient portal. Koopman, MD, MS Jack M. and Winifred S. The primary outcome is blood pressure at 6 months.

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Rethinking Clinical Trials

JULY 14, 2023

Tyson School of Medicine Slides Keywords Pragmatic Clinical Trial, GGC4H, Prevention Key Points Guiding Good Choices for Health Study (GGC4H) is about the Guiding Good Choices (GGC) intervention, a group-based program for parents and caregivers of younger adolescents (ages 9-14). 2) Can virtual GGC be delivered with fidelity?

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Drug Discovery World

JANUARY 9, 2023

Harvard investigators have developed a new cell therapy approach to eliminate established tumours and induce long-term immunity. . Using gene engineering, we are repurposing cancer cells to develop a therapeutic that kills tumour cells and stimulates the immune system to both destroy primary tumors and prevent cancer.” .

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Rethinking Clinical Trials

FEBRUARY 9, 2023

The study team’s health informatics group developed a novel clinical decision support (CDS) tool, called IMPROVE-DD VTE CDS, which can be integrated into different electronic health record (EHR) systems. The solution’s interface was developed using workflow analysis, multiple iterations of the tool and usability testing.

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Rethinking Clinical Trials

AUGUST 28, 2023

 Speakers Prof Sir Martin Landray, FMedSci Professor of Medicine & Epidemiology University of Oxford Chief Executive, Protas Khair ElZarrad, PhD, MPH Director, Office of Medical Policy Center for Drug Evaluation and Research (CDER) U.S. The new structure aims to provide clarity and better readability.

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Rethinking Clinical Trials

AUGUST 28, 2023

 Speakers Prof Sir Martin Landray, FMedSci Professor of Medicine & Epidemiology University of Oxford Chief Executive, Protas Khair ElZarrad, PhD, MPH Director, Office of Medical Policy Center for Drug Evaluation and Research (CDER) U.S. The new structure aims to provide clarity and better readability.

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Rethinking Clinical Trials

JANUARY 26, 2023

EVOLVE-MI has trial innovation through its Academic Research Organizations (AROs), who are also enrolling and understand challenges firsthand. Tags #pctGR, @Collaboratory1 The post Grand Rounds January 20, 2023: Collaborative Pragmatic Trials in Action: EVOLVE-MI (Mikhail Kosiborod, MD) appeared first on Rethinking Clinical Trials.

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Rethinking Clinical Trials

FEBRUARY 2, 2023

Russell, MD Assistant Professor, Department of Medicine Co-Director, Program in Medical ICU Research Division of Pulmonary, Allergy & Critical Care Medicine Assistant Medical Director, Birmingham Veterans Affairs Medical Center MICU University of Alabama at Birmingham Heersink School of Medicine Matthew W.

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Pharmaceutical Technology

FEBRUARY 22, 2023

Developed by Sanofi and Regeneron, Praluent was approved by the FDA in July 2015. Both drugs come with a high price tag. In its past statements shared with other outlets, Amgen stated that patents need to give researchers wide protection to incentivise new inventions. Amgen’s Repatha was greenlit a month later.

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Pharmaceutical Technology

MAY 15, 2023

Innovation S-curve for the pharmaceutical industry Peptide nano-particle conjugates is a key innovation area in the pharmaceutical industry By tagging peptides with nanoparticles, peptide nano-particle conjugates allow enhanced control over their biological behaviour, overcoming intrinsic limitations of the individual materials.

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Rethinking Clinical Trials

NOVEMBER 9, 2022

The goal of the CardioNerds Clinical Trials Network is to pair equitable enrollment with trainee development. To address these challenges, we decided to work with the CardioNerds network with a goal of pairing trial enrollment with trainee professional development. Forty-four programs participated.

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