Scienmag

FEBRUARY 25, 2021

Scott Devine, PhD 64 human genomes sequenced will serve as new reference for genetic variation and predisposition to human diseases Credit: NIH Researchers at the University of Maryland School of Medicine (UMSOM) co-authored a study, published today in the journal Science, that details the sequencing of 64 full human genomes.

Genome 57

Genome Genomics Genetics Medicine 57

pharmaphorum

SEPTEMBER 16, 2022

Alphabet subsidiary and precision health company Verily recently announced a breakthrough in its AI drug discovery GPCR research collaboration with Sosei Heptares. Kim recognised then, he said, that better tools for medicine needed to be developed, and that they still do. What, then, is the solution?

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Drug Discovery World

NOVEMBER 7, 2022

A new study led by Medical Research Council-funded researchers from UCL has found that tailoring the analysis of whole genome sequencing to individual patients could double the diagnostic rates of rare diseases. . Context . The study .

Genome 52

Genome Genomics Genetics Genetic Disease 52

Scienmag

APRIL 30, 2021

Researchers have identified a vulnerability in some cases of acute myeloid leukaemia that could be harnessed for targeted treatment of these poor-prognosis cancers Targeting a pathway that is essential for the survival of certain types of acute myeloid leukaemia could provide a new therapy avenue for patients, the latest research has found.

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Genetics Research Bioinformatics Medicine 75

Scienmag

JULY 12, 2021

USC researchers have achieved a better way to identify elusive DNA variants responsible for genetic changes affecting cell functions and diseases. Using computational biology tools, scientists at the university’s Dornsife College of Letters, Arts and Sciences studied “variable-number tandem repeats” (VNTR) in DNA.

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DNA Research Genetics Scientist 69

Scienmag

JANUARY 27, 2021

New research from the University of Illinois says yes. In a paper published in Evolutionary Bioinformatics, Illinois researchers show COVID-19 cases and mortality rates, among other […]. . – With cities around the globe locking down yet again amid soaring COVID-19 numbers, could seasonality be partially to blame?

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Scienmag

JANUARY 13, 2021

Credit: Delaneau Group Thousands of genetic markers have already been robustly associated with complex human traits, such as Alzheimer’s disease, cancer, obesity, or height.

Genome 57

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Drug Discovery World

FEBRUARY 17, 2023

A new multi-year strategic partnership between M2GEN and Zephyr AI will leverage clinicogenomic data, bioinformatics, and artificial intelligence to accelerate drug discovery and expanded use cases for oncology treatments. million lives around the world,” said Grant Verstandig, Co-Founder and Executive Chairman of Zephyr AI.

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Bioinformatics Drugs Licensing Licensing 52

pharmaphorum

JULY 5, 2022

Cell therapy specialist Mogrify has struck a deal with Japanese drugmaker Astellas to look at ways to deploy regenerative medicine to treat hearing loss caused by factors such as chronic exposure to loud noises. An estimated 1.57

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In-Vivo Bioinformatics Genetics Licensing 97

Scienmag

SEPTEMBER 22, 2020

Credit: Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai Bottom Line: Given the toll that the COVID-19 pandemic has taken on people’s health and lives worldwide, it is crucial to be able to accurately predict patients’ outcomes, including their chances of mortality from the disease.

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Development Genome Genomics Research 52

Drug Discovery World

APRIL 18, 2023

DDW’s Megan Thomas rounds up highlights from Tuesday 17 April at AACR 2023, from AI and mathematical oncology to winners of the AACR James S Ewing-Thelma B Dunn Award for Outstanding Achievement in Pathology in Cancer Research. Read more here. AACR James S. Ewing-Thelma B.

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Genetics DNA Research Bioinformatics 52

Scienmag

JULY 16, 2021

Credit: Vaughn Cooper PITTSBURGH, July 16, 2021 – For the first time ever, researchers from the University of Pittsburgh School of Medicine discovered that phages–tiny viruses that attack bacteria–are key to initiating rapid bacterial evolution leading to the emergence of treatment-resistant “superbugs.”

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Research Bacteria Medicine Bioinformatics 73

Scienmag

JANUARY 13, 2021

International Ukraine Genetic Diversity Project finds a quarter of the genetic variation in Europe, dramatically increasing information on population diversity and medical genetic variation Credit: Oakland University Today, the largest study of genetic diversity in Ukraine was published in the open science journal GigaScience.

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Scienmag

NOVEMBER 12, 2020

In a study that has unprecedented implications to advance both medicine and biodiversity conservation, researchers have sequenced 131 new placental mammal genomes, bringing the worldwide total to more than 250 In a study that has unprecedented implications to advance both medicine and biodiversity conservation, researchers have sequenced 131 new placental (..)

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Biobanking Medicine Genome Genomics 41

Scienmag

APRIL 8, 2021

Credit: IRB Barcelona In cancer, personalised medicine takes advantage of the unique genetic changes in an individual tumour to find its vulnerabilities and fight it. Researchers at IRB Barcelona led […].

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Scientist DNA Genetics Medicine 53

Scienmag

SEPTEMBER 7, 2020

Credit: Felix Petermann, MDC Hundreds of innovators, research pioneers, clinicians, industry leaders and policy makers from all around Europe are united by a vision of how to revolutionize healthcare.

Medicine 58

Medicine Research Bioinformatics Allergies 58

Scienmag

JANUARY 20, 2021

Now, computational research at Chalmers University of Technology, Sweden, shows that one reason could be significant genetic transfer between bacteria in our ecosystems and to humans. Credit: Jan Zrimec/Chalmers University of Technology Pathogenic bacteria in humans are developing resistance to antibiotics much faster than expected.

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Bacteria Genetics Development Research 97

Drug Discovery World

APRIL 14, 2023

The American Association for Cancer Research (AACR) will honour the following cancer researchers, physician-scientists, advocates, and journalists during its annual meeting to be held April 14-19 at the Orange County Convention Center in Orlando, Florida. June’s award lecture will be held on Sunday April 16 at 4:30pm ET.

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Genetics Research Medicine Clinical Research 52

Scienmag

JANUARY 8, 2021

Credit: University of Leeds Researchers have for the first time identified the way viruses like the poliovirus and the common cold virus ‘package up’ their genetic code, allowing them to infect cells.

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Packaging Packaging Genetics Research 94

Scienmag

SEPTEMBER 28, 2020

In an article published in Nature Genetics, researchers confirm that about 14% of all cases of cerebral palsy, a disabling brain disorder for which there are no cures, may be linked to a patient’s […].

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Gene Genetics Development Research 74

Scienmag

SEPTEMBER 4, 2020

Jonek The European Research Council (ERC) has awarded ERC Starting Grants to two researchers from Bielefeld University. million euros for top-level research in their disciplines. ERC Starting Grants for Professor Dr Martina Hofmanová and Dr Toni Goßmann Credit: Photo: Bielefeld University /S. They will each receive 1.5

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Research Bioinformatics Gene Genetics 56

XTalks

MAY 20, 2022

Do you possess laboratory skills, an analytical mindset and a penchant for research? A clinical scientist conducts research to help prevent illness and develops techniques to support patient diagnosis and treatment. They will often find themselves working in a healthcare or pharmaceutical field that supports human health research.

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Scientist Life Science Clinical Research Doctors 105

Scienmag

MARCH 30, 2021

— A reproducibility crisis is ongoing in scientific research, where many studies may be difficult or impossible to replicate and thereby validate, especially when the study involves a very large sample size. For example, to evaluate the validity of a high-throughput genetic […].

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Genome Genomics Genetics Research 45

Drug Discovery World

JULY 26, 2023

An industry overview of the role of the microbiome in precision medicine, and its interplay with research tools, diagnostics, and therapeutic development. Research increasingly demonstrates that within each discrete microbial environment (e.g., identifying single nucleotide polymorphisms or chromosomal rearrangements).

Medicine 52

Medicine Genome Genomics Bioinformatics 52

Scienmag

DECEMBER 16, 2020

15, 2020 — The Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has identified a specific genetic target that could help explain the tremendous variation in how sick those infected with COVID-19 become. Comparative analysis of human and animal coronaviruses strains implicates miR1307 PHOENIX, Ariz.

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Scienmag

JANUARY 29, 2021

In 2017, the Nobel Prize in Physiology or Medicine went to three scientists who uncovered the molecular mechanisms that control the circadian rhythm, otherwise known as the “wake-sleep” cycle.

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Gene Scientist Medicine Research 69

STAT News

MARCH 6, 2023

It works with commercial partners and researchers at the Washington University School of Medicine in St. Therapeutic vaccines represent the next frontier in cancer medicine. Louis to create a promising but yet-to-be-approved treatment known as a personalized neoantigen synthetic long peptide vaccine.

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XTalks

SEPTEMBER 28, 2020

Based on the genetic biomarker(s) identified, the most effective therapy targeting the specific molecular marker can be selected. The liquid biopsy will therefore help personalize medicines for patients based on the molecular features of their disease.

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Scienmag

MARCH 4, 2021

Researchers at Baylor College of Medicine show that analysis of the proteomics, or all the protein data, from aggressive human cancers is a useful approach to identify potential novel therapeutic targets.

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Protein Medicine Drugs Research 46

Scienmag

MARCH 12, 2021

UMD-led research identifies age-related changes to DNA and reveals longevity-related differences between bat species Credit: G. Tschapka A new study led by University of Maryland and UCLA researchers found that DNA from tissue samples can be used to accurately predict the age of bats in the wild. Wilkinson, G. Puechmaille, M.

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DNA Research Bioinformatics Genetics 98

Scienmag

NOVEMBER 18, 2020

Credit: SDSU For a slow-growing microbe that multiplies infrequently, Mycobacterium tuberculosis, the pathogen that causes tuberculosis (TB) has long puzzled researchers as to how it develops resistance to antibiotics so quickly, in a matter of weeks to months.

Bacterium 88

Bacterium Development Research Bioinformatics 88

Drug Discovery World

OCTOBER 25, 2023

DDW Editor Reece Armstrong speaks to Dr Darrell Green , Lecturer in RNA Biology Biomedical Research Centre Norwich Medical School University of East Anglia, about his work using next generation sequencing (NGS) and the areas the technology is impacting within drug discovery and development. The second concept is largely in oncology.

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pharmaphorum

SEPTEMBER 14, 2020

Last week geneticist Dr Charles Steward shared with us his experiences of searching for a genetic cause for his children’s rare neurological diseases. Here he gives us a deeper look at how genomic medicine is evolving and the barriers that are preventing it from reaching its full potential.

Genome 111

Genome Genomics Medicine Gene 111

Drug Discovery World

JULY 11, 2023

While the potential for better insights has grown, acquiring powerful tools that can harness that data, and turn it into useful, actionable information, has increasingly become one of the most important aspects of life science research. Advances in quantum computing are also showing early promise for increasingly complex data analyses.

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Big Data Development Life Science Drugs 40

Scienmag

MARCH 22, 2021

Credit: WEHI, Australia Melbourne researchers have revealed how melanoma cells are flooded with DNA changes as this skin cancer progresses from early, treatable stages through to fatal end-stage disease.

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Scienmag

SEPTEMBER 30, 2020

Researchers engineer RNA-targeting compounds that disable the pandemic coronavirus’ replication engine Credit: Scott Wiseman for Scripps Research JUPITER, FL – Sept.

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XTalks

DECEMBER 13, 2023

In 2023, biotechnology and pharmaceutical companies leverage cutting-edge technology and significant investments in research and development (R&D) to continue pushing the boundaries of innovation in the healthcare sector, transcending the challenges posed by the pandemic.

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