Scienmag

NOVEMBER 9, 2020

Preeclampsia-related gene expression in the placenta may correlate with vitamin D status during pregnancy, report researchers from the Medical University of South Carolina. Credit: Medical University of South Carolina According to the World Health Organization, preeclampsia affects between 2% to 8% of pregnancies.

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Gene Gene Expression Research Cardiology 52

Scienmag

AUGUST 20, 2020

In people with a single-gene variant that puts them at high risk for heart disease, breast cancer, or colorectal cancer, the rest of the genome can alter that risk Life can change dramatically when someone learns they are genetically predisposed to a disease, such as a condition called familial hypercholesterolemia, where a mutated gene can […]. (..)

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Genetics Gene Genome Genomics 41

Medical Xpress

MARCH 29, 2023

A team of researchers from Ohio University's Heritage College of Osteopathic Medicine has recently discovered a novel role of human-CIDEC gene in improving metabolic dysfunction and cardiovascular health.

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Protein Insulin Research Gene 69

Scienmag

JANUARY 26, 2021

Authors from the German Center for Diabetes Research (DZD) presented data showing that the longevity gene mammalian Indy (mINDY) is involved in blood pressure regulation in the Journal of Clinical Investigation (JCI) insight.

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Regulation Gene Research Cardiology 40

Scienmag

MARCH 31, 2021

Independent of cholesterol, gene variants raise risk of heart disease, diabetes, high blood pressure Credit: In-Hyuk Jung, PhD, Stitziel Lab High cholesterol is the most commonly understood cause of atherosclerosis, a hardening of the arteries that raises the risk of heart attack and stroke.

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XTalks

JULY 19, 2021

The test’s NGS technology achieves a clinical specificity of over 99 percent per condition and the test can detect over 99 percent of potential variants in each gene. As a preventative tool, the test can assist people in taking early action to help mitigate and even prevent health problems.

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Genetics Genome Genomics Gene 98

The Pharma Data

OCTOBER 27, 2021

Dietz MD, Professor of Genetic Medicine at The Johns Hopkins University School of Medicine in the United States, will join the Board of the Company as a Non-Executive Director. His lab has identified the genes for many of these conditions, for which he uses model systems to elucidate disease mechanisms. Dr Hal Dietz is Victor A.

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Scienmag

APRIL 28, 2021

— A national, University at Buffalo-led study on genes in pediatric cardiomyopathy demonstrates strong evidence for routine genetic screening in children with the disease. The study, published April 28 in […].

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Genetics Gene Clinical Trials Clinical Trials 93

Scienmag

MARCH 25, 2021

Decade-long search uncovers genes responsible for lacunar strokes, a major cause of vascular dementia Scientists have identified new genetic clues in people who’ve had small and often apparently ‘silent’ strokes that are difficult to treat and a major cause of vascular dementia, according to research funded by the British Heart Foundation (..)

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Genetics Gene Scientist Research 75

The Pharma Data

MAY 31, 2022

In the United States, the trial was initiated at Weill Cornell Medicine with Dr. Harini Sarva, M.D. About BlueRock Therapeutics BlueRock Therapeutics is a leading engineered cell therapy company with a mission to create authentic cellular medicines to reverse devastating diseases, with the vision of improving the human condition.

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Trials Engineer Clinical Trials Clinical Trials 52

The Pharma Data

FEBRUARY 21, 2022

Our leadership in cardiology, radiology and women’s health is recognized worldwide, and we are expanding our presence in oncology, working tirelessly to bring forward new approaches that can change the treatment paradigm for patients,” said Stefan Oelrich, Member of the Board of Management, Bayer AG and President of Bayer’s Pharmaceuticals Division.

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Scienmag

SEPTEMBER 24, 2020

New light is being shed on a little-known role of Y chromosome genes, specific to males, that could explain why men suffer differently than women from various diseases, including Covid-19.

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Gene Research Cardiology Genetics 60

Scienmag

FEBRUARY 10, 2021

Data demonstrates new increased diversity in genetic studies and provides new insights into population-specific diseases Researchers at the University of Maryland School of Medicine (UMSOM) and their colleagues published a new analysis today in the journal Nature from genetic sequencing data of more than 53,000 individuals, primarily from minority (..)

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Genetics Research Medicine Bioinformatics 71

Scienmag

AUGUST 11, 2020

New study identifies frequency of hormone therapy use and predictors of its use in women who underwent preventive oophorectomy as a result of carrying the BRCA gene CLEVELAND, Ohio (August 12, 2020)–Removal of the ovaries before natural menopause (surgical menopause) often exacerbates menopause symptoms and places women at increased risk for (..)

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Hormones Gene Cardiology Medicine 43

Scienmag

OCTOBER 22, 2020

Scientists cannot be expected to drop everything they’re working on to turn their attention to beating COVID-19, according to the winner of the 2019 Nobel Prize in Physiology or Medicine, Professor Sir Peter Ratcliffe.

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Research Scientist Medicine Cardiology 41

The Pharma Data

AUGUST 29, 2020

Presented at the ESC Congress 2020, the annual meeting of the European Society of Cardiology, the analysis evaluated the efficacy and tolerability of inclisiran on top of a maximally tolerated dose of statins, in two studies of more than 2,300 patients (of which 1,164 were on inclisiran) from the Phase III trials. 2020;382:1507-1519.

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Medicine Containment Trials Production 52

Scienmag

MAY 18, 2021

Scientists link genetic makeup of bacteria in the human gut to several human diseases We are truly never alone, not even within our own bodies. Human beings play host to trillions of bacteria, fungi, viruses, and other microorganisms that make up the human microbiome. In recent years, the mix of these resident bacteria, and the […].

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Bacteria Genetics Scientist Cardiology 74

Scienmag

NOVEMBER 19, 2020

Precise treatment leads to resolution of patient’s debilitating symptoms and complete remodeling of her lymphatic system Philadelphia, November 20, 2020–Researchers at Children’s Hospital of Philadelphia (CHOP) have resolved a severe lymphatic disorder in a girl with Noonan Syndrome that had led to upper gastrointestinal bleeding, (..)

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Research Cardiology Gene Genetics 67

Scienmag

JUNE 24, 2021

Team led by scientists at Cincinnati Children’s discover molecular process behind dangerous loss of heart muscle Credit: Cincinnati Children’s In many situations, heart muscle cells do not respond to external stresses in the same ways that skeletal muscle cells do.

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Scientist Cardiology Gene Medicine 52

Scienmag

OCTOBER 15, 2020

Benoit Bruneau and Katie Pollard study DNA folding to identify the genetic causes of congenital heart disease Credit: Photo: Gladstone Institutes SAN FRANCISCO, CA–October 15, 2020–The National Institutes of Health (NIH) has granted a 4D Nucleome award to support research by a group of scientists at Gladstone Institutes led by Benoit Bruneau, (..)

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DNA Genetics Scientist Research 54

Scienmag

APRIL 28, 2021

Credit: Unsplash Whether you hanker for a hard hit of caffeine or favour the frothiness of a milky cappuccino, your regular coffee order could be telling you more about your cardio health than you think. In a world first study of 390,435 people, University of South Australia researchers found causal genetic evidence that cardio health […].

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Genetics Research Cardiology Gene 52

Scienmag

SEPTEMBER 8, 2020

Salk study is the first to reveal ways cells from the human circulatory system change with age and age-related diseases Credit: Bersini, Schulte et al.

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Scientist Gerontology Cardiology Gene 54

Scienmag

MAY 17, 2021

Patients’ genetic profile strongly influences size of effect in early-phase trial People with extremely high levels of triglycerides (a type of fat in the blood) and a specific genetic profile saw a substantial reduction in triglycerides after taking the human monoclonal antibody evinacumab compared with those taking a placebo, in a study presented (..)

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Genetics Antibody Trials Gene Therapy 42

Scienmag

DECEMBER 22, 2020

By unleashing the power of an enzyme that limits blood vessel growth, it may be possible to develop new or better treatments for multiple health conditions. LA JOLLA, CA–Most living things need oxygen to grow and thrive. Even cancerous tumors.

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Development Cardiology Gene Medicine 40

Scienmag

SEPTEMBER 6, 2020

SCAD is poorly understood, and it’s so far impossible to predict which combination of genes and environmental triggers will lead […].

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Genetics Gene Cardiology Medicine 46

The Pharma Data

SEPTEMBER 15, 2020

Pfizer’s Rare Disease late-stage pipeline currently includes three gene therapy programs that, if successful, are expected to gain regulatory approval by the end of 2023, with an additional pipeline of 10 preclinical initiatives that are at various stages of maturity. Internal Medicine. approval in 2021. and -50.4%

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XTalks

AUGUST 2, 2023

With each passing year, pharmaceutical companies around the globe strive to deliver cutting-edge medicines, therapies and vaccines that impact the lives of millions. In this in-depth article, we embark on a captivating journey to uncover the top 30 pharma and biotech companies that have been instrumental in shaping the future of medicine.

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Sales Manufacturing FDA Approval Life Science 98

The Pharma Data

MAY 13, 2021

The Yale Journal of Biology and Medicine. Preventive Medicine Reports. Experimental & Molecular Medicine. Journal of addiction medicine. Journal of the American College of Cardiology. Western Journal of Medicine. Neuroendocrinology of obesity. Br Med Bull. 2014;109:73-82. DOI: 10.1093/bmb/ldu001. .

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