XTalks

FEBRUARY 21, 2024

Black participation in clinical trials, and the underrepresentation of minority groups in general in trials, remains low. It is therefore important to work towards increasing Black participation in clinical trials, which begins with understanding the barriers to participation and taking steps to address them.

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XTalks

AUGUST 16, 2024

The effectiveness of clinical trials often depends on the quality and depth of the data utilized. This rich data resource has significant potential to innovate clinical trials, providing real-world, timely insights that can enhance success and streamline trial processes.

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Clinical Trials Clinical Trials Trials Clinical Research 59

XTalks

DECEMBER 29, 2022

The life sciences and healthcare are among the biggest industries globally, and their significance was particularly highlighted during the past couple of years by the COVID-19 pandemic. Given the hyperfocus on the life sciences thanks to COVID, consumers appear to be more autonomous and vocal about their medical demands and choices.

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XTalks

MAY 16, 2023

Clinical trials for pulmonary fibrosis are being conducted to evaluate the effectiveness of novel therapies and interventions, providing hope for improved outcomes in the future. Pulmonary fibrosis is a serious condition that can significantly impact life expectancy.

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Clinical Trials Clinical Trials Trials Research 98

XTalks

FEBRUARY 28, 2024

Advancements in rare disease research are leading to innovative new treatments for various rare conditions, including genetic disorders, which make up just over 70 percent of all rare diseases. Subscribe to the Xtalks Life Science Podcast to never miss a new episode.

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Life Science Research Genetics Drugs 52

XTalks

SEPTEMBER 14, 2022

In this episode, Ayesha discussed the FDA approval of Sanofi’s enzyme replacement therapy Xenpozyme for the treatment of non-central nervous system (non-CNS) manifestations of acid sphingomyelinase deficiency (ASMD), a rare genetic lysosomal storage disease, in adults and pediatric patients.

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XTalks

DECEMBER 14, 2023

In an insightful interview with Xtalks , Cassadie Moravek, the Senior Director of Clinical Trial Portfolio and Program Management at the Pancreatic Cancer Action Network (PanCAN) , shares her perspective on the organization’s efforts in advancing pancreatic cancer research and patient care. Read on to learn more from Moravek.

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Clinical Trials Clinical Trials Trials Doctors 52

XTalks

MARCH 20, 2024

When it comes to leadership in clinical trials today, what qualities are necessary to navigate the evolving landscape of clinical research effectively? Continue reading to explore effective leadership in clinical trials. Can you begin by telling us about your experience in clinical research?

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Clinical Trials Clinical Trials Trials Clinical Research 52

XTalks

MAY 29, 2024

Recognized on May 30 each year, World MS Day brings together global communities, healthcare professionals and life sciences industries to share stories, raise awareness and support those affected by multiple sclerosis (MS). These seek to protect the nervous system from MS damage and slow disease progression.

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Clinical Trials Clinical Trials Trials Life Science 52

XTalks

SEPTEMBER 11, 2020

Expanding minority Americans’ access to care and clinical trials isn’t just the right thing to do. Clinical Trials Don’t Reflect Demographics. Why, then, are clinical trials so stubbornly homogeneous? Why, then, are clinical trials so stubbornly homogeneous? What Clinicians Are Struggling With.

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Clinical Trials Clinical Trials Trials Drugs 98

pharmaphorum

JUNE 11, 2021

Abel Archundia discusses how COVID-19 has highlighted the importance of securing clinical trials against cyber threats. However, data-intensive, decentralised clinical trials also present a major risk to healthcare participants through cybercrime and data privacy vulnerability. About the author.

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XTalks

NOVEMBER 7, 2022

Gleich, MD, FACS, Senior Vice President, Medical Department, and Dr. Christopher Huth, PhD, Senior Clinical Trial Manager, Clinical Trial Management. Liquid Biopsy Use in Oncology Clinical Trials. percent show less reliability). Optimal methods for bioinformatic analysis are still needed.

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Clinical Trials Clinical Trials Trials FDA Approval 96

XTalks

NOVEMBER 6, 2020

Canadian clinical-stage biotech company Symvivo Corporation has developed an oral COVID-19 vaccine that entered clinical trials this week. The first healthy volunteer was dosed with the vaccine in Australia as part of the bacTRL-Spike COVID-19 Phase I clinical trial. COVID-19 Clinical Trials.

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XTalks

FEBRUARY 25, 2022

There has been increasing awareness around the need for improving inclusion and diversity in clinical trials. As such, there has been a growing emphasis on efforts to achieve better and more accurate representations of minority and underrepresented populations like Black people in clinical studies. Personalized Medicine.

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Clinical Trials Clinical Trials Trials Research 52

XTalks

SEPTEMBER 13, 2024

Diverse clinical trials are a matter of equity and essential for the validity and reliability of research outcomes. Historically, racial and ethnically minoritized groups or populations have been excluded from clinical trials, leading to a lack of data on how different demographic subgroups respond to treatments.

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Trials Clinical Trials Clinical Trials Clinical Research 52

The Pharma Data

AUGUST 7, 2020

As the pharma industry stands firm in its commitment to advance the sector to fight Covid-19, news has emerged from the European Commission who intend to streamline the development of therapies using genetically modified organisms to treat Covid-19. CluePoints provides clinical studies with risk management support package during Covid-19.

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Clinical Trials Clinical Trials Gene Trials 52

XTalks

JULY 24, 2024

XTALKS WEBINAR: Digital Health Tools That Will Transform Cancer Treatment Live and On-Demand: Thursday, August 22, 2024, at 1pm EDT (10am PDT) Register for this webinar today to learn how pharmaceutical and life science technology companies are collaborating to harness digital health tools in oncology care delivery.

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Big Data Clinical Trials Clinical Trials Life Science 52

XTalks

JULY 29, 2024

This blog will discuss new US Food and Drug Administration(FDA)-approved treatments, promising clinical trials and the latest advancements in lung cancer research, providing hope for better patient outcomes. Here are some promising treatments currently in Phase II/III trials. billion in 2022 and is projected to reach $299.13

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XTalks

OCTOBER 16, 2024

This is Pfizer’s second FDA-approved treatment for a rare genetic blood disorder this year. Related: World Thrombosis Day 2024: Move Against Thrombosis This approval stems from the results of the Phase III BASIS trial, which evaluated the efficacy and safety of Hympavzi in patients with hemophilia A or B.

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XTalks

OCTOBER 15, 2024

The cancer link for the gene therapy was already known at the time of its approval as its label included a boxed warning for hematologic malignancies, including “life-threatening cases” of MDS. Prior to its approval, the FDA placed a clinical hold on Skysona’s development program in 2021 after a patient developed MDS following treatment.

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Gene Therapy Gene Clinical Trials Clinical Trials 98

XTalks

DECEMBER 20, 2023

As we step into 2024, the life sciences continue to evolve at an unprecedented pace, driven by technological innovation, a deeper understanding of human biology and the application of new technologies in areas like drug development and health wearables.

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XTalks

SEPTEMBER 9, 2024

Building DEI within life science organizations, particularly in the area of clinical research, is not just a social imperative but also a scientific one, ensuring that drugs developed are both safe and effective for the populations they are intended to serve. This dual focus can, however, introduce challenges.

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Clinical Research Research Clinical Trials Clinical Trials 82

XTalks

FEBRUARY 19, 2024

The team used the data and patient samples from a gB/MF59 Phase II trial in adolescent girls as a benchmark to assess the new mRNA-based vaccine. The comparison is particularly important as gB/MF59 demonstrated promise in Phase II clinical trials but did not advance to Phase III.

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Vaccination Vaccine Trials Clinical Trials 59

XTalks

SEPTEMBER 12, 2023

Life science podcasts have emerged as an invaluable tool for building connections with audiences in the digital era. Furthermore, we’ll explore the unique advertising opportunities that this platform offers, positioning brands at the forefront of the life science industry. The result?

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Life Science Branding Clinical Trials Clinical Trials 96

pharmaphorum

JANUARY 27, 2023

She knows only too well how understanding the importance of patient centricity is crucial to the success of any modern life sciences company – but how has the landscape changed since 2019? “I We talk a lot in clinical trials and drug development about benefit,” Dr Mullen said. But who is benefitting?

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Clinical Trials Clinical Trials Trials Development 111

XTalks

MARCH 28, 2024

For CRC, treatment options that are targeting genetic mutations such as BRAF , KRAS and HER2 have been developed. Building Cancer Awareness and Empowering Métis Youth: Featuring Jordyn Playne, President, Métis Nation of Ontario Youth Council – Xtalks Life Science Podcast Ep.

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Gene Editing Life Science Clinical Trials Clinical Trials 59

XTalks

SEPTEMBER 24, 2024

CDKL5 deficiency disorder (CDD) is a rare genetic condition caused by mutations in the CDKL5 gene, which is essential for brain development and function. Flatt Xtalks Clinical Edge is a magazine for clinical research professionals and all who want to be informed about the latest trends and happenings in clinical trials.

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Clinical Trials Clinical Trials Trials Development 52

XTalks

DECEMBER 28, 2023

BillionToOne, a company specializing in molecular diagnostics, has partnered with Janssen Research & Development, LLC, a Johnson & Johnson division, to conduct the AZALEA Phase III clinical trial globally. The trial is set to occur across the US, the European Union (EU) and selected global locations.

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Trials Clinical Trials Clinical Trials Antibody 85

XTalks

FEBRUARY 23, 2024

XTALKS WEBINAR: A Collaborative Approach to Advancing Access and Equity in Rare Disease Clinical Trials Live and On-Demand: Thursday, February 29, 2024 , at 11am EST (4pm GMT / UK) Register for this free webinar to join the discussion with clinical trial experts on a collaborative approach to patient-friendly trials in rare disease.

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Clinical Trials Clinical Trials Genetics Trials 82

XTalks

SEPTEMBER 6, 2024

As the co-founder of Blueprint Genetics, a proud member of the Quest Diagnostics family, I’ve witnessed firsthand the complexities and nuances involved in rare disease diagnostics and the development of orphan drugs. At Blueprint Genetics, we are committed to making sense of this complexity.

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Genetics Drugs Development FDA Approval 52

XTalks

JANUARY 26, 2023

The US Food and Drug Administration (FDA) recently granted approval for the Bruton tyrosine kinase inhibitor (BTKi) Brukinsa (zanubrutinib) based on the results from two Phase III clinical trials. Diagnosis is confirmed by a differential complete blood count and genetic testing.

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FDA Approval Life Science Clinical Trials Clinical Trials 86

XTalks

JUNE 18, 2024

XTALKS CLINICAL EDGE: Issue 2 — Elixirgen Therapeutics’ Interview Xtalks Clinical Edge is a magazine for clinical research professionals and all who want to be informed about the latest trends and happenings in clinical trials. This metaphor captures the essence of their therapeutic approach.

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Protein RNA Genetics Clinical Trials 52

XTalks

SEPTEMBER 26, 2024

The drug had initially been approved based on earlier promising results from the CENTAUR trial, a multicenter Phase II clinical trial with 137 ALS participants. The CENTAUR trial included a 6-month randomized, placebo-controlled phase and an open-label long-term follow-up phase.

Research 52

Research Clinical Trials Clinical Trials Trials 52

pharmaphorum

OCTOBER 7, 2020

There is enormous power in this genetic tool, which affects us all. It has not only revolutionised basic science, but also resulted in innovative crops and will lead to ground-breaking new medical treatments,” said Claes Gustafsson, chair of the Nobel Committee for Chemistry. What started as a curiosity?driven,

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XTalks

OCTOBER 26, 2021

AHP is a life-threatening genetic condition caused by an inherited deficiency in the metabolic enzyme hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD). Clinical trial results have shown that Givlaari reduces severe AIP symptoms by 74 percent. “This is a huge development for patients.”.

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Gene Silencing Gene Clinical Trials Clinical Trials 94

XTalks

JULY 15, 2024

The drug has been evaluated in five clinical trials for PBH. Congenital HI is a genetic disorder that causes excessive insulin production by the pancreas, which lowers plasma or blood sugar. If you want your company to be featured on Xtalks.com, please email ayeshar@xtalks.com.

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Drugs Insulin Life Science Marketing 52

XTalks

JULY 15, 2024

The drug has been evaluated in five clinical trials for PBH. Congenital HI is a genetic disorder that causes excessive insulin production by the pancreas, which lowers plasma or blood sugar. If you want your company to be featured on Xtalks.com, please email ayeshar@xtalks.com.

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Insulin Drugs Life Science Marketing 52