XTalks

FEBRUARY 21, 2024

Black participation in clinical trials, and the underrepresentation of minority groups in general in trials, remains low. It is therefore important to work towards increasing Black participation in clinical trials, which begins with understanding the barriers to participation and taking steps to address them.

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Clinical Trials Clinical Trials Trials Life Science 59

Pharmaceutical Technology

APRIL 13, 2023

Following the increased use of telemedicine during the Covid-19 pandemic, the potential of digital technologies in communication, data collection, and analysis has become increasingly realised by patients, healthcare systems, and clinical trial sponsors.

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Pharmaceutical Technology

JULY 7, 2022

Genetic mutations, both germline and acquired, are behind a large proportion of the most debilitating and sometimes life-threatening human diseases. But scientists have struggled to find effective treatments for many of these diseases since the dawn of modern medicine. A new frontier in cancer research.

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Gene Therapy Gene Medicine Genetics 245

XTalks

MARCH 20, 2024

When it comes to leadership in clinical trials today, what qualities are necessary to navigate the evolving landscape of clinical research effectively? Xtalks recently had the opportunity to discuss Enciso’s journey in the clinical research industry and her decision to join Regeneron.

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XTalks

MAY 17, 2023

The Foundation for the National Institutes of Health (FNIH) announced this week that the Accelerating Medicines Partnership Bespoke Gene Therapy Consortium (AMP BGTC) has selected eight rare diseases for its clinical trial portfolio. Of the more than 10,000 rare diseases, more than 80 percent are caused by genetic defects.

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Gene Therapy Clinical Trials Clinical Trials Gene 98

pharmaphorum

APRIL 26, 2022

Making sure clinical trials are diverse and representative of the populations they’re studying isn’t just the right thing to do to promote inclusivity and equity; it’s also just good science/clinical scientific practice. Potential barriers that exclude communities from clinical research.

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Clinical Trials Clinical Trials Trials Regulation 98

XTalks

DECEMBER 14, 2023

Research is ongoing to find better ways to diagnose and treat pancreatic cancer. Advances in precision medicine and immunotherapy offer new hope for targeted treatments. Please tell us more about your role as Senior Director, Clinical Trial Portfolio and Program Management at the Pancreatic Cancer Action Network.

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Clinical Trials Clinical Trials Trials Doctors 52

Rethinking Clinical Trials

MAY 10, 2023

Denny, MD, MS CEO, All of Us Research Program Slides Keywords Precision Medicine, All of Us Research Program Key Points The mission of the All of Us Research Program is to accelerate health research and medical breakthroughs, enabling individualized prevention, treatment, and care for all of us. .;

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Drug Discovery World

FEBRUARY 8, 2023

A diversity study has shown that clinical trials should use real world diseases epidemiology data, rather than US Census Bureau race and ethnicity data, to ensure enrolment reflects the populations affected by different diseases. For example, US Census Bureau data indicates 13.4%

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Clinical Research Research Clinical Trials Clinical Trials 97

Rethinking Clinical Trials

AUGUST 18, 2022

Professor of Medicine. The racism built into these categories does not go away when we do research. There are barriers at the health care professional and researcher level. The recruitment plan needs to include study materials that are tailored and accessible to the research population. ? ? ? ? ? ? ? ? ? ? ? ? ?. Speaker.

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Drug Discovery World

JANUARY 29, 2024

Leading experts in genomics, personalised medicine and drug discovery convened at the Precision Medicine Community Event in London to unveil the latest advancements shaping the future of healthcare. The post What are the key trends in genomics and precision medicine for 2024? appeared first on Drug Discovery World (DDW).

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Genome Genomics Medicine Biobanking 59

Drug Discovery World

APRIL 3, 2023

A team of researchers at the Keck School of Medicine of University of Southern California (USC) have found a drug with the potential for curbing painful hyperinflammation from osteoarthritis, according to results of an animal study. In trying to fix the problem, the immune system causes even more damage,” said Evseenko.

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Clinical Trials Clinical Trials Trials Drugs 52

Roots Analysis

JANUARY 22, 2024

However, these approaches are incompetent for dealing with intrinsic carcinogenic genetic abnormalities. This resulted in the discovery of an individualized concept of treatment known as oncology precision medicine which primarily utilizes the patient’s genomic information to provide gene-targeted diagnostics and therapeutics.

Medicine 40

Medicine Genetics Genome Genomics 40

pharmaphorum

MARCH 24, 2022

There’s a rich history of finding useful medicines from fungi, from the antibiotic penicillin to immune suppressant cyclosporine and cholesterol drug lovastatin. The post GSK partners LifeMine on fungi-derived medicines appeared first on. Image by jggrz from Pixabay .

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Medicine Genome Genomics Engineer 104

ACRP blog

JUNE 7, 2023

If you hadn’t already noticed, the clinical research enterprise has well and truly entered the era of “big data,” artificial intelligence (AI), and machine learning. Undoubtedly, the expectations for precision medicine are high,” Olsen adds.

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Big Data Clinical Research Research Clinical Trials 59

Cloudbyz

NOVEMBER 30, 2021

As a relatively young industry, it’s no wonder that the clinical trial industry tends to undergo rapid change. Decentralized Clinical Trials. Decentralized Clinical Trials (DCTs) are clinical trials that remove reliance on central research sites for clinical studies.

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Clinical Trials Clinical Trials Trials Clinical Research 52

Drug Discovery World

AUGUST 16, 2023

A new study has shed light on the genetic messages encoded by genes within ‘triple negative’ breast cancers (TNBC), and shows they could predict response to chemotherapy. The presence of these biomarkers could be used to accelerate the development of more personalised treatments for triple negative breast cancers.

Genetics 52

Genetics Gene Hormones RNA 52

Drug Discovery World

MAY 22, 2023

Not-for-profit medical research organisation LifeArc and techbio company PrecisionLife have agreed a strategic R&D collaboration to accelerate the discovery of targeted treatments for motor neurone disease (MND). LifeArc researchers will lead and coordinate target validation and drug discovery projects.

Medicine 52

Medicine Genotype Genetics Clinical Trials 52

XTalks

JANUARY 26, 2024

Technological advancements are revolutionizing cancer research and therapies. By editing these genes, researchers can effectively neutralize their cancer-promoting effects. Personalized medicine: One of the most exciting prospects of CRISPR/Cas9 in oncology is its contribution to personalized medicine.

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Research Gene Editing Gene Genetics 118

Drug Discovery World

DECEMBER 14, 2023

Dr Amrolia is Professor of Transplantation Immunology at the UCL Great Ormond Street Institute of Child Health and an international leader in CAR T-cell therapy for paediatric ALL, and ViroCell Biologics is a specialist viral vector CDMO for cell and gene therapy (CGT) clinical trials.

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Research Manufacturing Clinical Trials Clinical Trials 52

Worldwide Clinical Trials

NOVEMBER 27, 2023

In trials, Casgevy was shown to help prevent episodes of debilitating pain, known as vaso-occlusive crises, that often plague patients affected by sickle cell disease. sickle cell disease community and the millions around the globe who suffer from this genetic illness.

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Gene Editing Gene Gene Therapy In-Vivo 168

XTalks

NOVEMBER 7, 2022

“Liquid biopsies have demonstrated promising activity in multiple clinical settings, but the great enthusiasm and expectations around them can be harmful if not adequately managed,” said Dr. El Mustapha Bahassi, PhD, Director, Clinical Laboratory Sciences, at the global clinical research organization (CRO) Medpace.

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Clinical Trials Clinical Trials Trials FDA Approval 98

Scienmag

DECEMBER 3, 2020

In a randomized, controlled clinical trial, researchers found that patients who received genetic test results about the side effects of cholesterol-lowering medications did not have worse outcomes after one year A person’s genetic make-up can influence whether they might experience side effects from certain medications.

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Clinical Trials Clinical Trials Trials Genetics 44

pharmaphorum

OCTOBER 12, 2022

Now, he leads Whitelab Genomics as its artificial intelligence (AI) platform powers the development of genomic therapies – an emerging field in which genetic sequences are injected into cells to target and repair damaged genes. The evolving field of genomic medicine. This is just the beginning; the potential is enormous,” he says.

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Genome Genomics Medicine Development 104

XTalks

FEBRUARY 25, 2022

There has been increasing awareness around the need for improving inclusion and diversity in clinical trials. As such, there has been a growing emphasis on efforts to achieve better and more accurate representations of minority and underrepresented populations like Black people in clinical studies.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Research 52

Cloudbyz

JUNE 26, 2023

Generative artificial intelligence (AI) techniques are increasingly being applied in clinical research to enhance various aspects of medical data analysis, diagnosis, treatment planning, and drug discovery. This can aid in personalized medicine, disease management, and risk assessment, leading to improved patient care and outcomes.

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Clinical Research Research Clinical Trials Clinical Trials 77

Drug Discovery World

JUNE 2, 2023

Health data generated by hospitals, healthcare providers, research organisations and clinical trials hold the potential to advance research and innovation, improve patient care and accelerate drug development. Lifebit’s Trusted Research Environment technology provides real-world data on cancer patients.

Research 52

Research Compliance Clinical Trials Clinical Trials 52

pharmaphorum

SEPTEMBER 16, 2022

Alphabet subsidiary and precision health company Verily recently announced a breakthrough in its AI drug discovery GPCR research collaboration with Sosei Heptares. Kim recognised then, he said, that better tools for medicine needed to be developed, and that they still do. It also bodes well for improving clinical trial success rates.

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Development Research Drugs Clinical Trials 134

pharmaphorum

SEPTEMBER 28, 2022

Martin Mendoza, PhD, director of health equity and health science policy for the All of Us Research Program at the National Institutes of Health (NIH), tells pharmaphorum about the programme and how it will accelerate research for the benefit of all patients. Gathering data.

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Research Medicine Clinical Trials Clinical Trials 98

Drug Discovery World

FEBRUARY 12, 2024

Why has there been so little progress in medicine? After all, these failures come on top of decades and decades of research into these diseases. Animal research Unfortunately, most of the research into these diseases has been conducted on animals. Why has it been so unproductive?

Medicine 59

Medicine Genome Genomics Drugs 59

Drug Discovery World

SEPTEMBER 4, 2023

In the third and final part of this series of articles focused on plant-based medicines, DDW’s Megan Thomas evaluates therapeutic breakthroughs using plant-based products in drug discovery. In this study, researchers discovered how EGCG breaks apart tangles of the protein tau, a ‘hallmark’ of Alzheimer’s disease.

Medicine 59

Medicine Protein Containment Drugs 59

ACRP blog

APRIL 24, 2023

Courtney Burnett’s personal story, a brief history, and endless gratitude For patients and physicians alike, clinical research provides hope that ongoing innovation will offer new options to treat and even cure challenging illnesses. points out that modern healthcare and evidence-based medicine would not exist without clinical trials.

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Clinical Trials Clinical Trials Trials Medicine 98

Drug Discovery World

AUGUST 3, 2023

In the first part of this series of articles focused on plant-based medicines, DDW’s Megan Thomas evaluates the use of medical cannabis in drug discovery. Medical cannabis is often a first-thought when regarding plant-based medicines, but there remains public scepticism, arguably due to the regulations relating to the substance.

Medicine 52

Medicine Scientist Production Regulation 52

The Pharma Data

JUNE 18, 2023

These results reinforce the impact that innovative medicines can have in the prevention of migraine.” About Lilly Lilly unites caring with discovery to create medicines that make life better for people around the world. There were no new safety findings. Source link: [link]

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Clinical Trials Clinical Trials Trials Medicine 40

Scienmag

OCTOBER 21, 2020

(Nasdaq: BBIO) today announced a three-year collaboration agreement formed to advance cutting-edge academic discoveries in genetically driven diseases toward therapeutic applications.

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Genetics Research Gene Therapy Clinical Trials 75

The Pharma Data

AUGUST 7, 2020

As the pharma industry stands firm in its commitment to advance the sector to fight Covid-19, news has emerged from the European Commission who intend to streamline the development of therapies using genetically modified organisms to treat Covid-19. Regenerative medicine and advanced therapies thriving despite Covid-19 disruption.

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Clinical Trials Clinical Trials Gene Trials 52

Drug Discovery World

MAY 17, 2023

Leveraging historical trial databases has become commonplace in assessing the feasibility of trials in therapeutic areas with a large breadth of clinical development history. EHR data also has a key role to play in designing future clinical trials.

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Clinical Trials Clinical Trials Trials Genetics 52