XTalks

JANUARY 15, 2024

From the continuing trend of the rapid adoption of AI tools to the growing use of real-world evidence (RWE) in regulatory decision-making and a focus on enhancing data integrity, find out how clinical trials will evolve in 2024 to shape the future of medical research. percent from 2023 to 2033.

Clinical Trials 105

Clinical Trials Clinical Trials Trials Clinical Research 105

XTalks

DECEMBER 20, 2023

Check out this article to learn about the biotech companies that went public this year. The companies include a diverse range engaged in innovative approaches in areas like oncology, genetic medicines, inflammatory diseases, dermatology and cardiorenal therapy.

Life Science 59

Life Science Clinical Trials Clinical Trials FDA Approval 59

pharmaphorum

SEPTEMBER 11, 2020

Yet, for clinical trials worldwide, real-time access to data is not the norm – and that lack can create a cascading set of issues affecting every aspect of a study. What does this mean for clinical trials? Analysts at Pharma Intelligence decided to find out, surveying professionals involved in clinical data management.

Trials 98

Trials Clinical Trials Clinical Trials Pharma Companies 98

pharmaphorum

JULY 7, 2022

As this issue’s contributors discuss, by working together pharma companies and healthcare providers can significantly enhance oncology treatment for patients. Therapeutic cancer vaccine trials have an opportunity to leverage recent interest in vaccine technology to make headway in oncology, says Advanced Clinical’s Christopher Oelkrug.

Vaccination 52

Vaccination Vaccine Life Science Trials 52

pharmaphorum

NOVEMBER 30, 2020

“Our belief is that patients should understand the challenges associated with drug development and how those challenges impact them personally… It is emotionally challenging for patients who must put their faith in the hands of pharma companies”.

Gene Therapy 105

Gene Therapy Gene Antibody Clinical Trials 105

Pharmaceutical Technology

MAY 24, 2023

By Luisa Sterkel & Joana Loureiro , Tenthpin Consultants The promise and potential of cell and gene therapies (CGT) has emerged in the recent past and currently over 1.500 CGT are registered for clinical trials holding great hope for the treatment of challenging and uncurable diseases.

Clinical Trials 246

Clinical Trials Clinical Trials Gene Therapy Clinical Supply Chain 246

pharmaphorum

FEBRUARY 16, 2021

UK biotech Exscientia has signed a string of partnerships with pharma companies and other research-based organisations to apply its AI-based drug discovery platform. It is vital that we develop treatments that target neuroinflammatory mechanisms underlying dementia.”.

Research 119

Research Drugs Protein Development 119

pharmaphorum

MAY 26, 2022

Racial disparities are still commonplace in many clinical trials with white-ethnic groups often overrepresented amongst trial participants. Inadequate clinical trial representations of all populations can therefore leave underrepresented groups vulnerable due to the lack of subgroup-specific data.

Clinical Trials 143

Clinical Trials Clinical Trials Trials Medicine 143

pharmaphorum

SEPTEMBER 7, 2022

Pharma has a great opportunity ahead of it when it comes to conducting representative clinical trials. The processes used are now seeing huge infrastructure commitments, in order to cement their place in the development of future products and trials. Whilst this is an early area of research, pharma can turn the dial now.

Clinical Trials 98

Clinical Trials Clinical Trials Trials Genetics 98

pharmaphorum

MAY 4, 2022

The low rate of success is one of the contributors to the high cost and the slow R&D process that takes promising compounds through early testing and into the clinic. The challenge that the pharma industry faces is the lack of better alternatives to animal models.

Drugs 143

Drugs Licensing Licensing Pharma Companies 143

pharmaphorum

FEBRUARY 17, 2021

One group excelling in this space is the Genetic Alliance. Their work ranges from developing new services in partnership with the National Health Service (NHS) to working with the All Party Parliamentary Group on Rare, Genetic and Undiagnosed Conditions, and the Department of Health on the UK Strategy for Rare Diseases.

Life Science 98

Life Science Branding Genetics Trials 98

The Pharma Data

OCTOBER 20, 2020

In hopes to advance the best and brightest, MD Anderson, in partnership with The Focus Fund GP, has launched the Cancer Focus Fund to propel compelling investigational cancer therapies from preclinical development through Phase II clinical trials. Targeted therapies, genetic sequencing, gene editing, immunotherapies.

Clinical Trials 52

Clinical Trials Clinical Trials Gene Editing Trials 52

Drug Discovery World

SEPTEMBER 28, 2022

Its application in pharma, most commonly in drug discovery, has been steadily growing with global partnerships between tech vendors and pharma companies becoming more commonplace. According to Hampleton Patners’ latest Healthtech M&A market report2, digital health companies raised a total of $57.2

Pharma Companies 52

Pharma Companies Drugs In-Vivo Genetics 52

pharmaphorum

DECEMBER 21, 2020

As it’s just a messenger molecule, it does not affect the body’s own genetic code when it is injected as a vaccine – but what it does do is instruct cells to code for copies of a certain protein. Their technology is based on synthetic messenger RNA – short for ribose nucleic acid – which is a short transcript of a longer DNA code.

Vaccination 111

Vaccination Vaccine Doctors Doctor 111

pharmaphorum

OCTOBER 27, 2021

In the same statement, the agency admitted that “there remains some uncertainty about the drug’s clinical benefit”, with a label update occurring shortly after approval that limited Aduhelm’s use to patients with early stages of the disease – the same group as tested in clinical trials for the drug.

Clinical Trials 75

Clinical Trials Clinical Trials Trials Research 75

pharmaphorum

SEPTEMBER 18, 2020

But although it was dubbed a “dangerous game”, some companies came out on top… On 6th April 1999, two companies with similar science-based cultures and a shared vision of the pharmaceutical industry came together to form what’s now considered as one of the top ten pharma companies in the world: AstraZeneca.

Pharma Companies 116

Pharma Companies Sales Vaccination Vaccine 116

Drug Discovery World

FEBRUARY 6, 2024

As AI-designed drugs start to enter large-scale clinical trials, DDW’s Diana Spencer investigates how new digital tools are reinventing and reshaping drug discovery for the future. The company’s platform evaluated more than 11.4

Marketing 69

Marketing Medicine Genome Genomics 69

pharmaphorum

JANUARY 29, 2021

Since Macrae joined the company just four years ago, Sangamo has more than tripled its staff and raised $1.6 It has also built its own manufacturing site and launched partnerships with six big pharma companies. And ultimately we will be able to add genetic influences to diseases that don’t have a genetic cause.

Gene Editing 145

Gene Editing Gene Gene Therapy In-Vivo 145

Cloudbyz

MAY 19, 2021

Moreover, 12% of industrial clinical pipeline products and at least 16% of preclinical pipeline products consist of CGT. The primary drivers for growth include increasing cancer and genetic cases and predicated applicability of CGT as a treatment. 2 CAR-T cell therapies proposed by Bristol-Myers Squibb were approved by FDA in 2020.

Gene Therapy 52

Gene Therapy Gene Manufacturing Production 52

pharmaphorum

APRIL 8, 2021

In the UK we have world leading genetic sequencing capabilities. BioNTech seeks “new kind of pharma company”. When we submitted our clinical trial documents, we got feedback within a few days, which sped everything up,” he said. Remember, in 2020 much more people died from cancer than COVID-19. “I

Development 93

Development Drugs Vaccination Vaccine 93

pharmaphorum

JUNE 14, 2022

Despite more treatment options being a positive, Ben Hargreaves finds that this has raised issues over single-region clinical trials, leading to the FDA rejecting certain treatments and clarifying what is required for approval. Only last month , the US company Merck agreed to pay a potential $1.4 Single-region concerns.

Clinical Trials 98

Clinical Trials Clinical Trials Trials Development 98

The Pharma Data

NOVEMBER 27, 2020

This week, another pharma company revealed a new technology device that can detect if a patient is infectious or not, while the Russian government published results of its Sputnik V vaccine, claiming it is more than 95 per cent efficient 42 days after the first dose.

Vaccination 52

Vaccination Vaccine Immune Response Marketing 52

Delveinsight

AUGUST 4, 2021

Similarly, genetics, immune response, and environmental factors also influence the occurrence of Neurological Conditions. With the advancement in technology, today diagnostics testing such as neurological examination, brain scans, genetic screening, and other tests are available to examine the occurrence of Neurological Conditions.

Marketing 98

Marketing Genetics Development Clinical Development 98

Drug Discovery World

DECEMBER 14, 2023

As well as the Cancer Research UK Scotland Institute, Cancer Research UK awards grants to research groups at universities and funds Experimental Cancer Medicine Centres (ECMCs) in Glasgow and Edinburgh, which deliver clinical trials of new experimental treatments.

Drugs 75

Drugs Life Science Research Scientist 75

XTalks

DECEMBER 29, 2022

Given their precise targeting, gene therapies have largely been focused on oncology indications followed by rare genetic diseases. As such, most gene therapies in late-stage clinical trials are in oncology or rare disease indications. 4. Social Media Marketing.

Life Science 52

Life Science Gene Therapy Gene Manufacturing 52

pharmaphorum

MARCH 28, 2022

Built under a government tender, AION Labs comprises four large international pharma companies – AstraZeneca , Merck, Pfizer , and Teva – and another core partner, the Israel Biotech Fund. Yerushalmi states there are numerous ways AI can support the pharma process – from clinical trials to patient stratification.

Pharma Companies 98

Pharma Companies Antibody Protein Development 98

Drug Discovery World

OCTOBER 4, 2022

The pandemic might have affected the number of clinical trials taking place for cell and gene therapies, with activity decreasing by around 15% compared to 2020, but major therapies such as Novartis’ gene therapy drug for spinal muscular atrophy (SMA) Zolgensma still made it to market. . billion, compared to $19.9

Gene Therapy 52

Gene Therapy Drugs Gene Manufacturing 52

XTalks

DECEMBER 20, 2023

This includes analyzing how drug combinations may impact individual patients or groups of patients before even entering a clinical trial. With a staggering 90 percent of drugs failing in clinical trials, AI has the potential to help improve these statistics.

Life Science 119

Life Science Gene Editing Development Clinical Trials 119

pharmaphorum

DECEMBER 23, 2020

Pharma companies have also made headway in rare diseases as several pipeline projects came to fruition. In summer, Alnylam’s gene silencing drug Oxlumo, the first treatment for primary hyperoxaluria type 1 (PH1), an ultra-rare and life-threatening genetic disorder Oxlumo was approved in the European Union and the US.

Marketing 96

Marketing Gene Silencing Gene Drugs 96

Cloudbyz

SEPTEMBER 25, 2020

Clinical trials play a pivotal role in drug development. Time is also of the essence in drug development, as competitive product-to-market lead times help pharma companies improve profitability. Time spent on clinical trials involves investment and being able to predict ADRs assists with improving the success rate.

Pharma Companies 52

Pharma Companies Big Data Drugs Clinical Trials 52

pharmaphorum

OCTOBER 26, 2022

And the company lives its commitment to patient centricity through all its operations, Chiesi explained. For example, at the SSIEM Annual Symposium earlier this month, the company shared data on a new candidate for the treatment of Fabry disease, a rare genetic blood disorder. Caring for a global community.

Development 96

Development Trials Marketing Life Science 96

pharmaphorum

NOVEMBER 1, 2021

Delytact (teserpaturev) is a genetically engineered oncolytic herpes simplex virus type 1 (HSV-1) that was approved for marketing in Japan earlier this year, and received pricing approval in August at 1.43 million yen (around $12,500) per dose, according to a Pharma Japan report.

Genetic Engineering 122

Genetic Engineering Clinical Trials Clinical Trials Trials 122

Drug Discovery World

JANUARY 26, 2023

As such, 2022 saw a marked fall in ROI for global pharmaceutical companies and their research and development activities. According to research from Deloitte 1 , the average ROI in R&D for global pharma companies fell to just 1.2% in 2022, a steep decline compared to the record 6.8% the industry experienced in 2021.

Development 98

Development Drugs Clinical Trials Clinical Trials 98

Delveinsight

AUGUST 6, 2020

The hATTR diagnosis is mainly dependent on symptoms and can be confirmed via performing tissue biopsies, genetic testing, and imaging studies. Pharma companies like Alnylam Pharmaceuticals , Ionis Pharmaceuticals , Eidos Therapeutics, and many others are providing the thrust to the Hereditary transthyretin amyloidosis market forward.

Gene Silencing 52

Gene Silencing Protein Marketing Gene 52

pharmaphorum

NOVEMBER 27, 2022

A group representing pharma companies selling precision therapies for cancer has called for a change to the way genomic testing is done in Scotland, to make sure patients get access to targeted drugs. Let’s lead by doing things – by making decisions to lead.”

Genome 104

Genome Genomics Genetics Medicine 104

Drug Discovery World

AUGUST 16, 2022

Disparities resulting from genetic, environmental, social, and economic factors increase cancer risks in certain subpopulations, and negatively affect their health outcomes. In recent years, governments, institutes, pharma companies, and funding bodies have taken significant measures to proactively address cancer disparities.

Research 52

Research Clinical Trials Clinical Trials Trials 52

World of DTC Marketing

JANUARY 31, 2021

The venture capitalists funding them are looking for a big payday when a pharma company acquires them. I have been recruited by these companies who promise huge payouts when they are acquired if their drug shows promise in clinical trials. In pharma R&D returns have declined to 1.8 percent from 2018.

In-Vivo 187

In-Vivo Generic Drugs Gene Therapy Drugs 187