Drug Discovery World

AUGUST 14, 2023

Over the past few decades, the incredible progress in personalised medicine has led to the development of life-saving cell and gene therapies (CGT). The agencies also have different requirements for the selection of healthy donors in the development of allogeneic cell therapies. By 2030, it’s expected to more than double, to $34.3

Gene Therapy 52

Gene Therapy Marketing Gene DNA 52

The Pharma Data

JANUARY 4, 2021

The UC Santa Barbara research uses a method that addresses not only antibiotic overuse, but also the containment of genetically modified organisms (GMOs). “If The process described in the research was previously developed by a former graduate student research in O’Malley’s lab, Justin Yoo.

Bacteria 52

Bacteria Engineer Genetics Genetic Engineering 52

The Pharma Data

DECEMBER 14, 2020

”) platform to transform drug discovery and development, and identify patients who will benefit from its portfolio of targeted oncology therapeutics, announced today new scientific data that substantiates blood brain barrier permeability (BBB) for its drug candidate LP-184. . DALLAS , Dec. Lantern’s A.I.

Drugs 52

Drugs Genome Genomics DNA 52

Drug Discovery World

NOVEMBER 15, 2022

The brainchild of multidisciplinary experts in computer science, physics, engineering, and biology, the field of synthetic biology has not only rapidly progressed in the last few decades but it’s also becoming more accessible and cost-effective. Rapid and accurate DNA synthesis .

DNA 98

DNA Drugs Antibody Engineer 98

Pharmaceutical Technology

OCTOBER 26, 2022

Gene therapy uses DNA to manipulate cells and correct defective genes, whereas cell therapy is the infusion or transplantation of cells into a patient. New doors were opened in the 2000s with the development of genome editing, such as CRISPR-Cas9, which introduces molecular tools to change existing DNA.

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Gene Therapy Gene Marketing Manufacturing 130

The Pharma Data

NOVEMBER 27, 2020

Nasdaq:RYTM), a biopharmaceutical company aimed at developing and commercializing therapies for the treatment of rare genetic diseases of obesity, announced today that the U.S. Forward-Looking Statements This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995.

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FDA Approval Genetic Disease Genetics Clinical Trials 52

XTalks

AUGUST 10, 2021

The test was developed by researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University, the Massachusetts Institute of Technology (MIT) and several Boston area hospitals. However, unprocessed saliva contains enzymes that degrade various molecules, which can lead to a high rate of false positives.

RNA 105

RNA Containment DNA Engineer 105

XTalks

DECEMBER 13, 2023

In 2023, biotechnology and pharmaceutical companies leverage cutting-edge technology and significant investments in research and development (R&D) to continue pushing the boundaries of innovation in the healthcare sector, transcending the challenges posed by the pandemic.

Genetics 111

Genetics Vaccination Vaccine DNA 111

Roots Analysis

AUGUST 31, 2023

Gene switches can be regulatory proteins or specific DNA sequences that act to either switch on or off the expression of a gene. Basic Components of Gene Switch Gene switches are composed of noncoding DNA sequences and transcription factors. Therefore, engineered T-cell responses must be regulated to prevent severe side effects.

Gene 40

Gene Gene Therapy Gene Expression Regulation 40

The Pharma Data

FEBRUARY 25, 2021

to support their development. In August 2020, the company acquired IdentiGEN, a leader in DNA-based animal traceability solutions for Livestock and Aquaculture. Poultry Sense Ltd. is an innovator in health and environmental monitoring solutions for the poultry industry. Specific terms of the agreement were not disclosed.

Production 52

Production Vaccination Vaccine Marketing 52

XTalks

FEBRUARY 11, 2021

A batch of Pfizer’s COVID-19 vaccine, BNT162b, developed in conjunction with Germany’s BioNTech, takes about 110 days to make. The company is on track to fulfill the 200 million-dose order put in by the US government by May, but hopes to have more available as engineers improve systems on the go. coli bacteria.

Manufacturing 52

Manufacturing Vaccination Vaccine DNA 52

Roots Analysis

MARCH 16, 2023

Messenger ribonucleic acid (mRNA) is a single-stranded molecule that is complementary to a gene’s DNA. It is important in the process of protein synthesis because mRNA is responsible for transferring genetic information from DNA to ribosomes, which then decodes the genetic information into a protein.

Vaccination 52

Vaccination Vaccine DNA Protein 52

XTalks

MAY 4, 2021

Researchers at the University of California San Francisco (UCSF) and the Whitehead Institute have developed a novel CRISPR-based tool called “CRISPRoff” that can switch off genes in human cells through epigenetic editing without altering the genetic sequence itself. Epigenetic Editing with CRISPR. pyogenes dCas9.

DNA 98

DNA Gene Gene Silencing Genome 98

Drug Discovery World

AUGUST 10, 2022

Finally, in 2017, after years of improving T cell engineering techniques, the first chimeric antigen receptor (CAR) T cell therapy received FDA approval. Developing the first CAR T cell therapy. To overcome this evasion tactic, the CAR protein was developed to recognise other markers on cancer cells.

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Manufacturing Gene Genome Genomics 98

The Pharma Data

AUGUST 3, 2021

Revenue growth was 12 percent when excluding effects of 2020 COVID-related stocking patterns, revenue from COVID-19 antibodies and recent business development. Business Development/Other Developments. Research and development expenses increased 20 percent to $1.673 billion, or 24.8 on a non-GAAP basis.

Antibody 52

Antibody Sales Production Development 52

XTalks

MAY 4, 2021

Researchers at the University of California San Francisco (UCSF) and the Whitehead Institute have developed a novel CRISPR-based tool called “CRISPRoff” that can switch off genes in human cells without editing the genetic sequence itself. These modifications regulate gene expression without altering the sequence or structure of DNA.

DNA 52

DNA Gene Gene Silencing Genome 52

Roots Analysis

FEBRUARY 15, 2022

Over time, medical researchers have been able to further develop their understanding of the intricacies of ADC design and have also improved the development process of these complex pharmacological interventions. ADC Cytotoxic Payloads / Warheads Developers. Want additional details on the ADC Payloads / Warheads Developers?

Contract Manufacturing 52

Contract Manufacturing Manufacturing Marketing Containment 52

Drug Discovery World

NOVEMBER 30, 2023

Lightcast is developing a novel, programmable microfluidic platform that allows precise and highly flexible control of individual microdroplets using software-generated light patterns. GSK has developed high-throughput mammalian and E.

Antibody 59

Antibody Protein Engineer In-Vivo 59

Roots Analysis

FEBRUARY 13, 2023

It transfers genetic information form to DNA to ribosomes, a specialized structure, or organelle, which decodes genetic information into a protein. With the help of genetic engineering, synthetic mRNAs can express proteins, as they structurally resemble a natural mRNA.

Manufacturing 52

Manufacturing Drug Delivery Systems Genetic Engineering RNA 52

Drug Discovery World

DECEMBER 15, 2022

These platforms all induce double strand cuts in the chromosomal DNA that can be sealed by the cell, leading to a specific gene disruption, or resulting in a new target site for inserting DNA segments. Reduce/eliminate chromosomal disruptions caused by double-strand DNA breaks. In one example, Choi et al.

Gene Editing 52

Gene Editing Gene In-Vivo Genome 52

The Pharma Data

OCTOBER 19, 2020

Spectrum’s self-contained saliva collection kit provides critical sample consistency while suspending and neutralizing viral RNA transcripts completely inactivating the live virus. “The SDNA-1000 was engineered to innovate molecular diagnostic applications using saliva,” said Jeremy Johnson, VP of Engineering at Spectrum Solutions.

RNA 52

RNA DNA Engineer Packaging 52

Drug Discovery World

MARCH 27, 2023

Genomics is driving a revolution in drug development and, in the long run, the state of public healthcare. Today, thanks to incredible technological advances, scientists can sequence a genome in under 24 hours 1. One outcome of this rapid development is data. Jack Dix , Head of Healthcare Strategy and Consulting at Kainos, expands.

Genome 52

Genome Genomics Research Scientist 52

Drug Discovery World

MAY 4, 2023

The potential of drug targets Over the next 50 years, new targets emerged and drugs were developed against them. Recombinant DNA technology and improved protein purification techniques further contributed to our understanding and explorations of drug targets. Thus, there was a dire need for new and effective drug targets.

Medicine 52

Medicine Protein Drugs Bioassay 52

XTalks

FEBRUARY 3, 2021

Johnson & Johnson’s single-shot DNA vaccine candidate was shown to have an overall effectiveness of 66 percent in preventing moderate to severe COVID-19. Johnson & Johnson’s DNA Vaccine. The DNA vaccine was created using Janssen’s AdVac technology platform that is designed for rapid vaccine development.

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Vaccination Vaccine Trials Protein 103

XTalks

SEPTEMBER 14, 2020

“Vaccine Nationalism” Could Prove the Undoing of COVID-19 Containment. And in truth, the companies the White House picked were pretty savvy as several are current front-runners in the race to develop a vaccine. The company is also in collaboration with Ridgeback Biotherapeutics to develop a novel oral antiviral treatment for COVID-19.

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