Drug Discovery World

APRIL 24, 2024

Recombinant adeno-associated viruses (rAAVs) are considered a promising delivery system for gene therapy medicines. The event will feature experts Daniel Jachimowicz, Senior Bioscience Scientist at AstraZeneca BioPharmaceuticals R&D, Sweden, and Bastian Schiffthaler, Senior Data Scientist at AstraZeneca BioPharmaceuticals R&D, Sweden.

Genome 52

Genome Genomics DNA Gene Therapy 52

Pharmaceutical Technology

FEBRUARY 3, 2023

The field of genomic medicine has reached a true turning point. With scientists fervently developing mRNA vaccines, nucleic acid therapeutics, and viral vector-based gene therapies, clinicians are set to have a growing number of tools available to treat a wide range of conditions, from infectious diseases to genetic disorders and more.

Genome 244

Genome Genomics Medicine Gene Therapy 244

Scienmag

JUNE 25, 2021

A new study by UC Davis researchers confirms the low likelihood that SARS-CoV-2 contamination on hospital surfaces is infectious. The study, published June 24 in PLOS ONE, is the original report on recovering near-complete SARS-CoV-2 genome sequences directly from surface swabs.

Contamination 41

Contamination Genome Genomics Research 41

Roots Analysis

OCTOBER 24, 2023

Owing to the advancement in clinical pharmacology and oncology domain, and the rising demand for targeted therapeutics and precision medicines, high potency active pharmaceutical ingredients (HPAPIs) and cytotoxic drugs have become one of the key areas of interest to researchers and drug manufacturers across the globe.

Manufacturing 40

Manufacturing Hormones Contamination Containment 40

Roots Analysis

SEPTEMBER 20, 2023

Cell therapies are based on the premise that the patient’s own cells ( autologous ), or those from a healthy donor ( allogeneic ), can be genetically re-programmed to combat various diseases. Contamination is a key concern when it comes to manufacturing cell therapy products.

Manufacturing 40

Manufacturing Production Contamination Gene Therapy 40

The Pharma Data

JANUARY 6, 2021

Two boys, a 23-month-old and a 6-year-old, developed lung cancers that proved an exact genetic match to cervical cancers within their mothers at the time of birth, Japanese researchers report. In both cases, doctors used genetic testing to positively link the mothers’ cervical cancers to the lung cancers in their sons.

Vaccination 52

Vaccination Vaccine Doctors Doctor 52

Drug Discovery World

FEBRUARY 28, 2023

As we turn our focus to new potential applications and disease areas for the platform, scientists and companies must consider the potential life-saving impact on rare, inherited diseases, says Archana Gupta , PhD, staff scientist in genetic sciences at Thermo Fisher Scientific.

Genetics 52

Genetics Genetic Analysis Vaccination Vaccine 52

XTalks

FEBRUARY 26, 2021

The tree originates from the Indian subcontinent and had been used medicinally since as early as the 1300s. Instead, Susan taught him how to cook, mend, embroider, garden and prepare herbal medicines. He also experimented with peanut-based medicines, such as antiseptics, laxatives and goiter medications. Henrietta Lacks.

Scientist 69

Scientist Research Genetics Cosmetics 69

XTalks

NOVEMBER 7, 2022

However, Dr. Bahassi reported that the selection of CTCs using this method is often not very efficient and the CTC population is usually highly contaminated with leukocytes. FoundationOne ® Liquid CDx (Foundation Medicine; end-to-end commercial provider). Bahassi during the webinar and is shown in Table 1.

Clinical Trials 98

Clinical Trials Clinical Trials Trials FDA Approval 98

Roots Analysis

SEPTEMBER 18, 2023

Biologics: Gene therapy and cell therapy-based futuristic treatments fall under the category of advanced therapy medicinal products ( ATMPs ) and offer opportunities to individuals suffering from a variety of illnesses, including various types of cancers.

Engineer 52

Engineer Containment In-Vivo Production 52

Drug Discovery World

AUGUST 10, 2022

Cells from solid tumours are genetically heterogeneous both between and within tumours, making it challenging to identify a single, selective antigen target for treatment. Although this type of contamination has not yet been reported in humans, RCVs can form rapidly growing T cell neoplasms, another type of cancer. Clinicaltrials.gov.[link].

Manufacturing 98

Manufacturing Gene Genome Genomics 98

Drug Discovery World

AUGUST 16, 2022

Disparities resulting from genetic, environmental, social, and economic factors increase cancer risks in certain subpopulations, and negatively affect their health outcomes. Cancer risks also increase in areas with water contaminants or polluted air. Cancer health disparities and underlying contributing factors .

Research 52

Research Clinical Trials Clinical Trials Trials 52

The Pharma Data

MAY 13, 2021

every day are contaminated with at LEAST ONE TOXIC ingredient. The REAL problem lies in the fact that most of the foods we eat today have been Genetically Modified. These ingredients can be harmful and even LIFE THREATENING. These ingredients are responsible for putting your health at risk. million deaths in the United States alone.

Production 52

Production Containment Genetics Doctors 52

Drug Discovery World

MAY 11, 2023

This high level of quality control is also demanded and regulated by regulatory agencies such as the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA), which consider HCPs a critical quality attribute (CQA). ” New England Journal of Medicine 385.18 (2021): 1680-1689. coli, and Pichia cells. 2022): 947.

Production 52

Production Gene Protein Vaccination 52

Pharmaceutical Technology

APRIL 27, 2023

When combined with rapid advancement in delivery technologies, mRNA has the potential to lead to breakthroughs in the development of tailored treatment approaches in a wide range of indications from cancer to rare genetic disorders while enabling rapid responses to emerging threats.

Manufacturing 130

Manufacturing RNA Contamination Vaccination 130

XTalks

SEPTEMBER 14, 2020

CanSino Biologics is developing a vaccine that involves snipping a bit of the virus’ genetic code off and coupling it with a harmless virus to provoke a SARS-CoV-2 immune response. Several laboratories have already shown that they can detect genetic material from the virus in wastewater. million confirmed cases with over 72,000 deaths.

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Vaccination Vaccine Antibody Life Science 92