Roots Analysis

MARCH 8, 2023

Over time, various research studies have demonstrated the potential of exosomes ( membrane bound extracellular vesicles) in disease diagnosis, drug delivery and therapeutic applications. Targeted Drug Delivery: Ability to cross blood brain barrier cause lesser systemic effects and low toxicity.

RNA 52

RNA Drug Delivery DNA Development 52

The Pharma Data

APRIL 8, 2021

Leadership in DNA damage response demonstrated in multiple presentations for AZD5305, a next-generation PARP1 selective inhibitor. Data for AZD5305 will demonstrate how the next wave of DNA damage response medicines can build on the success of PARP inhibitors, potentially allowing patients to stay on treatment longer.

DNA 52

DNA Medicine Genome Genomics 52

Drug Discovery World

JANUARY 17, 2023

It also doesn’t do fantastically well in continuing to express the enzymes the editing tool uses as molecular scissors to make cuts in the DNA to be edited. We’re hoping to use what we’ve learned so far about LNPs to develop an improved gene editor delivery system.” .

Gene Editing 98

Gene Editing Gene Gene Therapy Genetics 98

Delveinsight

FEBRUARY 25, 2021

Beam adds to drug delivery stable with USD 120 Million GuideTx buy. The gene-editing technologies, which have reached the clinic, CRISPR, zinc finger nucleases, and TALENs, make their edits by nicking DNA at the target site. If they eliminated the T cells, the therapy stopped working.

DNA 52

DNA In-Vivo Genetics Medicine 52

The Pharma Data

JUNE 7, 2023

LNPs are spheric drug delivery bodies which can be equipped with therapeutic payloads for intracellular delivery. In addition to mRNA, Acuitas LNP can be used to deliver a range of different nucleic acid therapeutics including small interfering RNA (siRNA), antisense oligonucleotides and DNA.

Gene Therapy 40

Gene Therapy Gene Gene Editing In-Vivo 40

pharmaphorum

OCTOBER 6, 2022

Now in widespread use, it has assisted pharmaceutical development, DNA mapping, and the creation of more fit for purpose materials in the years since. Nonetheless, it has been Carolyn Bertozzi who has taken click chemistry to the next level. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”

Drug Delivery 52

Drug Delivery DNA Medicine Research 52

Drug Discovery World

OCTOBER 18, 2023

Such therapies have become an appealing drug modality for multiple conditions, including monogenic disorders, cancers, and infectious diseases.

Gene Therapy 65

Gene Therapy Gene Clinical Trials Clinical Trials 65

Drug Discovery World

NOVEMBER 17, 2022

It is believed that the term synthetic biology was created in 1970 by geneticist, Waclaw Szybalski 1 as work was being carried out on the development of DNA sequencing and synthesis techniques. This could have significant implications for our understanding of biology, in treating illness and in drug delivery.

Bacteria 52

Bacteria Engineer Gene Genetics 52

Delveinsight

SEPTEMBER 2, 2021

In this case, Delfi is developing a highly sensitive and specific assay intended for comprehensive and cost-effective distribution and adoption by utilizing an advanced machine learning algorithm to the circulating DNA fragment patterns, which can be evaluated through low-cost sequencing.

Marketing 72

Marketing Radiology Drugs Drug Delivery 72

Roots Analysis

MARCH 16, 2023

Messenger ribonucleic acid (mRNA) is a single-stranded molecule that is complementary to a gene’s DNA. It is important in the process of protein synthesis because mRNA is responsible for transferring genetic information from DNA to ribosomes, which then decodes the genetic information into a protein.

Vaccination 52

Vaccination Vaccine DNA Protein 52

Roots Analysis

FEBRUARY 13, 2023

It transfers genetic information form to DNA to ribosomes, a specialized structure, or organelle, which decodes genetic information into a protein. Additionally, they also require appropriate drug delivery systems to efficiently administer the intervention (in a manner that they can avoid degradation by cellular endonucleases).

Manufacturing 52

Manufacturing Drug Delivery Systems Genetic Engineering RNA 52

Drug Discovery World

APRIL 29, 2024

Dr Andrew Lewis, Chief Scientific Officer; Kieron Hall, Chief Marketing Officer; and Eric Bironneau, Chief Business Officer, Quotient Sciences: Lewis has held various scientific leadership positions at Quotient and was previously Director of Novel Drug Delivery Technologies at Ipsen.

Drugs 52

Drugs Sales Gene Therapy Life Science 52

Roots Analysis

FEBRUARY 18, 2022

These short, single-stranded DNA or RNA molecules have various applications in biopharmaceutical and biotechnology industries including, genetic testing, basic research, forensic analysis and other analytical procedures. Our Social Media Platform. Web: [link]. LinkedIn: [link]. Twitter: [link]. Medium: [link]. Pinterest: [link].

Contract Manufacturing 52

Contract Manufacturing Manufacturing Drug Delivery Systems RNA 52

FDA Law Blog

JANUARY 5, 2023

The current Team Lead for Injection Devices in CDRH’s Division of Drug Delivery and General Hospital Devices and Human Factors noted that depending on the product, the pre-market path for a connected combination product might require an IND, IDE, or a determination that it is a medical device data system , which are not regulated as devices.

Regulation 59

Regulation Production Drug Delivery Insulin 59

Roots Analysis

JANUARY 3, 2024

While numerous cardiovascular drug delivery devices and drug eluting stents are accessible for treating these conditions, treatment options for AF, including the anti-arrhythmic drugs, frequently prove ineffective.

Marketing 40

Marketing Protein Drug Delivery Development 40

Roots Analysis

OCTOBER 22, 2023

In the last few years, researchers have become interested in using in vitro transcribed (IVT) mRNA as a drug delivery agent. It is important to highlight that IVT mRNAs are structurally similar to natural mRNAs and can be used to express proteins through genetic engineering.

RNA 40

RNA Protein Genetics Gene Expression 40

Drug Discovery World

NOVEMBER 9, 2023

The first three include: Sungjin Park, PhD, CEO, Onegene Biotechnology, on: ‘UniStac: Enzyme-mediated conjugation technology for accelerated development of tetraspecific NASH drug’. Klaus Wagenbauer, PhD, Founder & CEO, Plectonic, on: ‘Programmable DNA-origami-based T cell engagers: PTE’.

Engineer 52

Engineer Antibody Protein In-Vivo 52

Pharmaceutical Technology

APRIL 24, 2023

The next wave came from early research into liposomes and lipid nanoparticles, both of which are used for drug delivery. Liposomes have the same function as lipid nanoparticles in drug delivery but have a simpler formulation. Lipid nanoparticle drug delivery was in the spotlight during the Covid-19 pandemic.

Drug Delivery 147

Drug Delivery Vaccination Vaccine Research 147

XTalks

OCTOBER 1, 2020

Xtalks spoke with WeiQi Lin, MD, PhD, executive vice president, research & development, and principal scientist at DURECT Corporation — a company focused on developing drugs and drug delivery methods in therapeutic areas with significant unmet need — about her transition from academia to industry.

Scientist 52

Scientist In-Vitro Research Life Science 52