Drug Discovery World

FEBRUARY 6, 2024

Researchers from the University of Oslo, University of Chicago Pritzker School of Medicine, and Insilico Medicine used an AI target discovery engine to analyse transcriptomic data to identify dual targets for cancer and ageing 5. Digital tech is also helping researchers to find target candidates for some of the most challenging disease areas.

Marketing 69

Marketing Medicine Genome Genomics 69

Drug Discovery World

AUGUST 5, 2022

Three key members of the team – Dr Raquel Sanches-Kuiper, Vice President of Technology, Dr Matthew Hayes, Chief Technology Officer and John Edgell, Head of Cloud Engineering – explain how the company is doing this and what it means for the advancement of DNA synthesis in the lab. The next goal is to optimise the technology. “At

DNA 52

DNA Engineer Gene Sequencing Gene 52

Drug Discovery World

SEPTEMBER 15, 2023

Under the terms of the agreement, Orbit will deploy its bead-based peptide display engine to discover peptide leads specific to targets related to specific tumours. The collaboration will harness the capabilities of Orbit’s peptide display engine to identify peptide candidates specific to tumour-associated targets.

Engineer 52

Engineer DNA Development Marketing 52

BioPharma Reporter

JULY 20, 2023

Twist Bioscience, a biotech company manufacturing synthetic DNA, and Cancer Research Horizons, the innovation engine at the core of Cancer Research UK, have announced an agreement under which Cancer Research Horizons will license the entire Twist Biopharma Solutions Library of Libraries.

Research 40

Research DNA Engineer Licensing 40

Drug Discovery World

MAY 25, 2023

DNA Script: SYNTAX DNA printing platform Using the company’s EDS technology, the SYNTAX platform can synthesise up to 96 highly accurate, ready-to-use DNA oligos with maximum lengths of up to 120nt in less than 24 hours in the laboratory. The platform works with the SYNTAX Hi-Fidelity reagent kits for synthesising longer oligos.

Production 52

Production Reagent DNA Drugs 52

Pharmaceutical Technology

JUNE 23, 2022

The increased infection rate of Covid-19 indicates the requirement for an alternative treatment development pipeline instead of the intensive process to launch new drugs to market, the researchers said.

Drugs 130

Drugs Protein Genome Genomics 130

Pharmaceutical Technology

FEBRUARY 15, 2023

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely. Regeneron has a market cap of $78.64

Gene Expression 130

Gene Expression Gene Genetic Engineering Antibody 130

Pharmaceutical Technology

FEBRUARY 23, 2023

Moderna Genomics general manager and chief scientific officer Eric Huang said: “Through our collaboration with Life Edit, we hope to harness the power of gene editing technologies as part of our broader research and development engine, helping to advance our mission and deliver on the promise of mRNA.”

Gene Editing 147

Gene Editing Gene In-Vivo Gene Therapy 147

pharmaphorum

MAY 7, 2021

Founded by Nobel prize winner Emmanuelle Charpentier, CRISPR Therapeutics has been at the forefront of the gene editing technology and has refined it to the point where it can be used to accurately edit DNA to correct genetic conditions or modify cells to fight disease.

Gene Editing 52

Gene Editing Gene Genetic Engineering DNA 52

Drug Discovery World

MAY 16, 2023

New South African company NewBiologix has launched with the aim of developing a proprietary and breakthrough platform for the advanced engineering of cell lines used to manufacture gene and cell therapies.

Production 52

Production Gene Therapy Gene Bioinformatics 52

Drug Discovery World

MAY 7, 2024

However, despite these advancements in process optimisation and cell culture engineering, there remain areas that we need to improve. DC: Antibodies have and remain a large product class within the biopharmaceutical market. RA: What are some of the current limitations for producing mAbs?

Antibody 59

Antibody Production Manufacturing Engineer 59

Drug Discovery World

JULY 22, 2022

To date, the centre has helped 27 companies achieve a combined market capitalisation of £790 million. . Synthetic biology is an emerging field of science that combines methodologies from engineering and biology to design or re-design biological systems to produce useful and sustainable new products. SynbiCITE .

DNA 52

DNA Life Science Engineer Development 52

Pharmaceutical Technology

MARCH 9, 2023

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely. Regeneron Pharmaceuticals is the leading patent filer in transgenic murine models. Sanofi and F.

In-Vivo 130

In-Vivo Antibody Genetics Gene 130

Drug Discovery World

NOVEMBER 17, 2022

The rapidly growing area of synthetic biology – including molecular biology, biotechnology, biophysics, and genetic engineering – is having a marked impact on the drug discovery landscape. SkyQuest Technology recently released a report: Global Synthetic Biology Market Insights, which highlights the sector’s value and potential.

Bacteria 52

Bacteria Engineer Gene Genetics 52

The Pharma Data

SEPTEMBER 11, 2021

By leveraging our unique ability to manufacture DNA at scale, we can construct proprietary antibody libraries precisely designed to match sequences that occur in the human body. The core of the platform is a proprietary technology that pioneers a new method of manufacturing synthetic DNA by “writing” DNA on a silicon chip.

Antibody 52

Antibody DNA Containment Manufacturing 52

The Pharma Data

JANUARY 31, 2021

(NASDAQ: ILMN), the global leader in DNA sequencing and array-based technologies, and Sequoia Capital China , a leading investment firm, today announced a collaboration to catalyze the startup ecosystem in China with the launch of the Sequoia Capital China Intelligent Healthcare Genomics Incubator, Powered by Illumina.

Genome 52

Genome Genomics Life Science DNA 52

Cloudbyz

MARCH 6, 2024

Unlike traditional small molecule drugs, which are chemically synthesized, biologics are produced through complex biotechnological processes, often involving recombinant DNA technology. Biosimilars have the potential to lower healthcare costs, increase market competition, and improve patient access to biologic therapies.

Gene 72

Gene Immune Response Manufacturing Gene Therapy 72

pharmaphorum

OCTOBER 12, 2022

David Del Bourgo (CEO and co-founder, Whitelab Genomics) has always been passionate about introducing disruptive, innovative technologies to markets. We thought, there has to be something to help use data to make [drug developers] more efficient in bringing therapies to market faster, and at a lower price,” Del Bourgo explains.

Genome 99

Genome Genomics Medicine Development 99

Drug Discovery World

JULY 31, 2023

Matt Hill , Founder and CEO of Elegen writes about the importance of innovation in DNA synthesis to address critical bottlenecks in biotherapy development. Regardless of the type of disease targeted, at the core of biotherapy development is synthetic biology and the use of synthetic DNA to programme specific behaviours within living cells.

DNA 52

DNA Medicine Manufacturing Production 52

pharmaphorum

JANUARY 29, 2021

‘Cutting edge’ is, for once, a truly apt description when it comes to gene editing – both because the field is pushing medicine into areas we might never have dreamed possible, and because these technologies involve literally cutting DNA at a specific point in the genome. The company’s primary technology is its zinc finger (ZF) platform.

Gene Editing 144

Gene Editing Gene Gene Therapy In-Vivo 144

Pharmaceutical Technology

OCTOBER 26, 2022

The biotherapeutics market is rapidly growing, with 2021 seeing the highest-ever cell and gene therapy approval number. Gene therapy uses DNA to manipulate cells and correct defective genes, whereas cell therapy is the infusion or transplantation of cells into a patient. The future of cell and gene therapies.

Gene Therapy 130

Gene Therapy Gene Marketing Manufacturing 130

The Pharma Data

DECEMBER 14, 2020

The global GBM treatment market is projected to reach $3.3 representing the largest market. engine along with algorithms tuned to predict BBB permeability played an important role in helping determine which CNS cancers and which genomically-defined subtypes of CNS cancer should be prioritized for development. .

Drugs 52

Drugs Genome Genomics DNA 52

Roots Analysis

DECEMBER 12, 2023

The technology providers offering these types of technologies work on engineering / modifications of antibodies. The classical potent drugs killed tumor cells by inhibiting crucial cellular processes and by interfering with DNA. ADC conjugation technologies were mainly focused on solving the very first issue with ADCs.

Antibody 40

Antibody Manufacturing Drugs RNA 40

Drug Discovery World

FEBRUARY 20, 2023

Indee Labs and GenScript have formed a research collaboration with the aim to develop a DNA knock-in kit for Hydropore to enable large transgene inserts above the 5kb limit for AAV. The post Companies unite to advance non-viral CRISPR cell engineering appeared first on Drug Discovery World (DDW).

Engineer 52

Engineer DNA Life Science Gene 52

Roots Analysis

JANUARY 28, 2024

Conclusion Owing to the increasing popularity of big data in healthcare domain, there is a huge impact of big data in healthcare market size. Throughout her career, Jayita has contributed to over six syndicate market research reports, covering a wide range of trending domains.

Big Data 40

Big Data Medicine Marketing Clinical Trials 40

Drug Discovery World

NOVEMBER 15, 2022

The brainchild of multidisciplinary experts in computer science, physics, engineering, and biology, the field of synthetic biology has not only rapidly progressed in the last few decades but it’s also becoming more accessible and cost-effective. Rapid and accurate DNA synthesis .

DNA 98

DNA Drugs Antibody Engineer 98

pharmaphorum

MARCH 8, 2022

Darina Shopova (DS): My first job, in 2005, was as a structural CAD engineer in my home country of Bulgaria. In October 2021, I joined the engineering department at Envair Technology, designing isolators. Darina Shopova is design engineer at Envair Technology, working on the design and development of rigid isolators.

Life Science 97

Life Science Engineer Scientist Doctors 97

The Pharma Data

OCTOBER 19, 2020

The company’s suite of market-leading molecular profiling offerings assesses DNA, RNA and proteins to reveal a molecular blueprint that helps physicians and cancer patients make more precise and personalized treatment decisions. Europe , Asia and other international markets. Caris provides services throughout the U.S.,

Life Science 52

Life Science Clinical Trials Clinical Trials RNA 52

pharmaphorum

JUNE 1, 2021

The widespread use of pill presses by criminal gangs means that they can change production and ingredients rapidly to satisfy market demand. Microtaggants are uniquely encoded materials that are virtually impossible to replicate or reverse engineer. This had led to a corresponding rise in the supply of counterfeit drugs.

Medicine 52

Medicine DNA Pharmacy Production 52

Drug Discovery World

FEBRUARY 14, 2024

While a typical chemisty, manufacturing and controls (CMC) timeline from DNA to Investigational New Drug (IND) application in 2015 would have been approximately 24 months, by 2023 the same pathway was expected to take only 10 months. Consistent and reliable supply chains have also become a key consideration.

Protein 59

Protein Vaccination Vaccine Manufacturing 59

Pharmaceutical Technology

FEBRUARY 15, 2023

Within the emerging innovation stage, cell therapy for ocular disorders, coronavirus vaccine components, and DNA polymerase compositions are disruptive technologies that are in the early stages of application and should be tracked closely. Nucleases are enzymes that hydrolytically cleave the phosphodiester backbone of DNA.

Gene Splicing 130

Gene Splicing Gene Recombinant DNA Technology DNA 130

Drug Discovery World

JULY 11, 2023

Drug discovery and development timelines can span 10-15 years or more from initial discovery to market approval and typically require the analysis of massive amounts of data. This knowledge enabled cell line engineering campaigns that boosted yield and stability across various production bottlenecks.

Big Data 40

Big Data Development Life Science Drugs 40

Drug Discovery World

OCTOBER 16, 2023

James Barder, CEO of Futura says: “The UK is a hotspot for life science innovation and an ideal home for Futura Medical, which has developed Eroxon, a breakthrough topical gel formulation for erectile dysfunction – now sold in the UK and other international markets.

Drugs 75

Drugs Life Science Gene Therapy Genome 75

Drug Discovery World

JULY 5, 2023

Global Cancer Segment Market Manager at Agilent Technologies, recently sat down with DDW Editor Reece Armstrong to tell us about the developments in the ‘golden age’ of cancer research. As part of his graduate work he invented the gel-shift or EMSA assay for the study of protein-DNA interactions. Mark Garner, PhD.,

Research 98

Research Protein Scientist Immune Response 98

Drug Discovery World

NOVEMBER 9, 2023

Ahead of protein and antibody engineering conference PEGS Europe 2024 in Lisbon, DDW’s Megan Thomas looks at what to expect from each track of the annual biologics technology meeting. Klaus Wagenbauer, PhD, Founder & CEO, Plectonic, on: ‘Programmable DNA-origami-based T cell engagers: PTE’.

Engineer 52

Engineer Antibody Protein In-Vivo 52

The Pharma Data

FEBRUARY 25, 2021

In April 2019, Merck Animal Health announced the completion of its acquisition of market leading brands Allflex Livestock Intelligence, Sure Petcare and Biomark as leaders in emerging digital technology with animal identification, animal monitoring and smart data management for Livestock and Companion Animals. About Merck Animal Health.

Production 52

Production Vaccination Vaccine Marketing 52

Roots Analysis

MARCH 16, 2023

Messenger ribonucleic acid (mRNA) is a single-stranded molecule that is complementary to a gene’s DNA. It is important in the process of protein synthesis because mRNA is responsible for transferring genetic information from DNA to ribosomes, which then decodes the genetic information into a protein.

Vaccination 52

Vaccination Vaccine DNA Protein 52