DNA, Genetic Disease and RNA - Clinical Research Informer

Turning science into business: Amplifying mRNA by targeting regRNAs

Drug Discovery World

APRIL 17, 2024

DDW’s Diana Spencer speaks to Josh Mandel-Brehm , CEO of Massachusetts-based biotech CAMP4, to understand the role regulatory RNAs play in gene expression and how the founders overcame the challenge of launching a business based on brand new science. DS: You describe your therapeutics as RNA Amplifiers. How do they work?

Gene Expression

Gene Expression Gene Genetic Disease RNA

Gene Therapy and Pharmacokinetics

Camargo

JULY 27, 2021

It is a comprehensive term which encompasses a large variety of therapy products including viral and bacterial vectors, plasmid DNA, human gene editing technology, and patient-specific cellular gene therapy. For example, it is beneficial to administer RNA treatments for some lung diseases directly to the disease site through inhalation.

Gene Therapy

Gene Therapy Gene Gene Editing Genetics

Moderna partners with Life Edit for mRNA gene editing therapies

Pharmaceutical Technology

FEBRUARY 23, 2023

The collaboration will combine the mRNA platform of Moderna with the gene editing technologies suite, including the base editing capabilities of Life Edit for the development of curative therapies to treat challenging genetic diseases.

Gene Editing

Gene Editing Gene In-Vivo Gene Therapy

Next Generation Sequencing (NGS) Library Preparation Kits Market: Current Scenario and Future Potential

Roots Analysis

FEBRUARY 21, 2022

Advancement in DNA sequencing technologies have resulted in noteworthy developments in various healthcare-related research fields, such as diagnostics and personalized medicine. As per our analysis, majority of the kits use purified RNA / DNA as the input sample. Diverse Landscape of NGS Library Preparation Kits.

Marketing

Marketing Gene Sequencing DNA Genome

Why genomic healthcare data matters in the development of new therapies

Drug Discovery World

NOVEMBER 7, 2022

From a general healthcare perspective, access to this sort of data is invaluable, but this is particularly noteworthy in that DNA tests have historically been limited in these regions on account of cost and availability of practitioners, services and resources.

Genome

Genome Genomics Development Genetics

General Design Methods for mRNA Drugs

Pharma Mirror

APRIL 21, 2024

This represents an increasingly promising field of precision medicine, holding significant prospects for preventing and treating numerous challenging or genetic diseases. Messenger RNA (mRNA) is a single-stranded ribonucleic acid transcribed from the DNA chain, carrying the encoding information for protein synthesis.

In-Vitro

In-Vitro Drugs Genetic Disease RNA

The future outlook for mRNA therapies

Drug Discovery World

APRIL 30, 2024

Messenger RNA (mRNA) has come into focus within the drug discovery and development as an exciting tool to deliver genetic information. mRNA is a molecule made up of a single strand of ribonucleic acid (RNA). We believe it can now do the same for rare diseases.” “We

RNA

RNA Protein Vaccination Vaccine

Key Trends in the Life Sciences to Look Forward to in 2022

XTalks

DECEMBER 22, 2021

The RNA Revolution: From mRNA Vaccines to RNA Editing. The age of RNA is officially here, and it’s here to stay as more than a passing life science trend. RNA technology is not new nor has its potential been surprising. RNA in the Making. So why did this perceived RNA ‘revolution’ take so long?

Life Science

Life Science RNA Vaccination Vaccine

Top 10 Fastest Growing Biotech Companies in 2023

XTalks

DECEMBER 13, 2023

Related: Top 30 Pharma Companies in 2023: Statistics and Trends 1) Moderna Compound annual growth rate: 415 percent Moderna, headquartered in Massachusetts, is a prominent biotechnology company specializing in RNA therapeutics, particularly mRNA vaccines. In the third quarter of 2023, the company’s revenue surged to $63.7

Genetics

Genetics Vaccination Vaccine DNA

Epigenetic Editing with CRISPR Might Be Easier Than We Thought

XTalks

MAY 4, 2021

Researchers at the University of California San Francisco (UCSF) and the Whitehead Institute have developed a novel CRISPR-based tool called “CRISPRoff” that can switch off genes in human cells through epigenetic editing without altering the genetic sequence itself. Epigenetic Editing with CRISPR. pyogenes dCas9.

DNA

DNA Gene Gene Silencing Genome

Generating Over a Billion Cells with CRISPR for Next Generation Cell Therapies

XTalks

AUGUST 29, 2022

This technology has powerful implications for therapeutic uses, such as replacing mutated or disease-causing genes or increasing the activity of cancer-fighting cells. Viral vectors have traditionally been used in gene editing where the shells of viruses carry the template DNA into cells, but this method has its disadvantages.

Gene Editing

Gene Editing DNA Gene Genome

Using CRISPR to Edit the Epigenome Might Be Easier Than We Thought

XTalks

MAY 4, 2021

Researchers at the University of California San Francisco (UCSF) and the Whitehead Institute have developed a novel CRISPR-based tool called “CRISPRoff” that can switch off genes in human cells without editing the genetic sequence itself. These modifications regulate gene expression without altering the sequence or structure of DNA.

DNA

DNA Gene Gene Silencing Genome

Unlocking the potential of mRNA for the future treatment of rare diseases

Drug Discovery World

FEBRUARY 28, 2023

Genetic analysis tools such as Sanger sequencing by Capillary Electrophoresis (CE) and qPCR are an integral part of the vector construction process to confirm and validate that the correct sequence of the gene is inserted into the vector backbone. The mRNA transcripts are then purified from the IVT reaction.

Genetics

Genetics Genetic Analysis Vaccination Vaccine

Clinical Catch-Up: December 21-25 | BioSpace

The Pharma Data

DECEMBER 27, 2020

Galidesivir is a broad-spectrum antiviral, an adenosine nucleoside analog that blocks viral RNA polymerase. STP705 is a small interfering RNA (siRNA) therapy that leverages a dual-targeted inhibitory property and polypeptide nanoparticle (PNP)-enhanced delivery to knock down both TGF-beta1 and COX-2 gene expression. Most Read Today.

Trials

Trials Antibody Gene Therapy Clinical Trials

Covid-19 vaccine success bolsters nanoparticle drug delivery research

Pharmaceutical Technology

APRIL 24, 2023

Since then, the field of nanomedicine has steadily progressed to reach high points such as the successful use of nanotechnology to deliver messenger RNA (mRNA)-based Covid-19 vaccines. Langer, now a David H. These could feature in the next four to five years. Free Report How is the Biopharmaceutical industry evolving?

Drug Delivery

Drug Delivery Vaccination Vaccine Research

Clinical Research Informer

Turning science into business: Amplifying mRNA by targeting regRNAs

Gene Therapy and Pharmacokinetics

Trending Sources

Moderna partners with Life Edit for mRNA gene editing therapies

Next Generation Sequencing (NGS) Library Preparation Kits Market: Current Scenario and Future Potential

Why genomic healthcare data matters in the development of new therapies

General Design Methods for mRNA Drugs

The future outlook for mRNA therapies

Key Trends in the Life Sciences to Look Forward to in 2022

Top 10 Fastest Growing Biotech Companies in 2023

Epigenetic Editing with CRISPR Might Be Easier Than We Thought

Generating Over a Billion Cells with CRISPR for Next Generation Cell Therapies

Using CRISPR to Edit the Epigenome Might Be Easier Than We Thought

Unlocking the potential of mRNA for the future treatment of rare diseases

Clinical Catch-Up: December 21-25 | BioSpace

Covid-19 vaccine success bolsters nanoparticle drug delivery research

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