Pharmaceutical Technology

FEBRUARY 3, 2023

The field of genomic medicine has reached a true turning point. The established method for this process is a triple transfection using three different DNA plasmids. Better transfection reagents and efforts to automate the currently highly manual and inconsistent process could also make a difference, he adds.

Genome 244

Genome Genomics Medicine Gene Therapy 244

Roots Analysis

AUGUST 28, 2022

As a result, industry and non-industry stakeholders, are on the lookout for advanced platforms that can simultaneously capture the arrangement of multiple biomolecules (DNA, RNA, proteins and others) with single-cell or subcellular resolution. 70+ spatial Genomics solutions are developed by industry and non-industry players.

Genome 52

Genome Genomics RNA Genome Project 52

pharmaphorum

FEBRUARY 3, 2021

However, caveats surrounding the stochastic off-target outcomes of cleaving both strands of the DNA helix to elicit a gene modification remain a source of concern. Traditional CRISPR-Cas9 technology relies on generating a DSB in the DNA to facilitate a genetic modification. Base editing to get cell therapies on point.

Gene Editing 98

Gene Editing Gene DNA Engineer 98

Drug Discovery World

DECEMBER 15, 2022

These platforms all induce double strand cuts in the chromosomal DNA that can be sealed by the cell, leading to a specific gene disruption, or resulting in a new target site for inserting DNA segments. Reduce/eliminate chromosomal disruptions caused by double-strand DNA breaks. In one example, Choi et al.

Gene Editing 52

Gene Editing Gene In-Vivo Genome 52

Drug Discovery World

JULY 18, 2023

Rolf Turk , Senior Manager, Genomics Medicine at Integrated DNA Technologies, examines how CRISPR is being used to enhance cancer therapies. Nucleic acid-based diagnostics, which typically require PCR reagents and laboratory equipment, are crucial for identifying, treating, and preventing common infectious diseases.

DNA 98

DNA Genome Genomics RNA 98

The Pharma Data

DECEMBER 2, 2020

Results show the protocol demonstrated a 30Gb+ yield of long DNA reads raw data of an E. The FMv8 protocol introduces a needle-aspirate-based, cell-resuspension step prior to cell lysis that boosts DNA recovery. Elsewhere around the globe: RevoluGen – U.K.-based Financial details of the agreement were not disclosed.

Drugs 52

Drugs Gene Editing Genome Genomics 52

The Pharma Data

MARCH 20, 2021

The Challenge: The demands of many labs simultaneously beginning COVID-19 screening programs are leading to a scarcity of resources like pipette tips and reagents. delays where reagents are in. professor in Functional Cancer Genomics and Applied. DNA biomarker services in an accredited environment. The MANTIS.

Reagent 52

Reagent RNA Bioinformatics Medicine 52

Drug Discovery World

JUNE 6, 2023

The only way we’re going to do that was improved diagnostic techniques.” At the meeting, Jordan says we are seeing improvements in circulating tumour DNA, circulating tumour cell diagnosis, as well as ways of detecting tumours before they are detectable through standard methodologies, such as CT scans. It’s a 1.5

Protein 52

Protein DNA RNA Research 52

Drug Discovery World

FEBRUARY 8, 2023

This helps ensure a high concentration of loaded capsids and adequate removal of impurities, such as host cell proteins and DNA. In AAV therapeutics, empty capsids are those that are not packaged with the therapeutic DNA. A crucial part of the AAV workflow is the purification of viral vectors.

Gene Therapy 52

Gene Therapy Gene Antibody Production 52

The Pharma Data

OCTOBER 14, 2020

ERS Genomics – Ireland’s ERS Genomics signed an agreement with FASMAC Co., Under the terms of the non-exclusive agreement FASMAC acquires the right to use CRISPR/Cas9 technology and commercialize tools and reagents associated with it. The patent is valid through 2038. Ltd of Japan.

Clinical Trials 52

Clinical Trials Clinical Trials Manufacturing Trials 52