Scienmag

JANUARY 12, 2022

Pacific time to coincide with the study’s publication in The New England Journal of Medicine Media contact: Hanae Armitage at (650) 725-5376 (harmitag@stanford.edu) Fastest DNA sequencing technique helps undiagnosed patients find answers in mere hours A new ultra-rapid genome sequencing approach developed by Stanford Medicine scientists and their collaborators (..)

DNA 62

DNA Genome Genomics Scientist 62

Scienmag

MAY 2, 2022

WINSTON-SALEM, NC – May 2, 2022 — Wake Forest Institute for Regenerative Medicine (WFIRM) scientists working on CRISPR/Cas9-mediated gene editing technology have developed a method to increase efficiency of editing while minimizing DNA deletion sizes, a key step toward developing gene editing therapies to treat genetic diseases.

Gene Editing 58

Gene Editing DNA Gene Development 58

Drug Discovery World

APRIL 16, 2024

Recombinant adeno-associated viruses (rAAVs) are considered a promising delivery system for gene therapy medicines. This webinar will highlight how long-read nanopore sequencing as a comprehensive and sensitive QC method for rAAVs were evaluated — which is supporting internal research activities at AstraZeneca.

Packaging 52

Packaging Packaging Genome Genomics 52

Drug Discovery World

APRIL 24, 2024

The event will feature experts Daniel Jachimowicz, Senior Bioscience Scientist at AstraZeneca BioPharmaceuticals R&D, Sweden, and Bastian Schiffthaler, Senior Data Scientist at AstraZeneca BioPharmaceuticals R&D, Sweden. The event will take place on 13 May, 4PM BST.

Genome 52

Genome Genomics DNA Gene Therapy 52

Scienmag

JULY 12, 2021

USC researchers have achieved a better way to identify elusive DNA variants responsible for genetic changes affecting cell functions and diseases. Using computational biology tools, scientists at the university’s Dornsife College of Letters, Arts and Sciences studied “variable-number tandem repeats” (VNTR) in DNA.

DNA 69

DNA Research Genetics Scientist 69

Drug Discovery World

APRIL 17, 2024

The event will feature experts Daniel Jachimowicz, Senior Bioscience Scientist at AstraZeneca BioPharmaceuticals R&D, Sweden, and Bastian Schiffthaler, Senior Data Scientist at AstraZeneca BioPharmaceuticals R&D, Sweden. The event will take place on 13 May, 4PM BST.

DNA 52

DNA Genome Genomics Gene Therapy 52

Scienmag

APRIL 1, 2021

Salk scientists reveal new insights into neurodegenerative disorders and potential for genetic therapies Credit: Salk Institute/Waitt Advanced Biophotonics Center LA JOLLA–(April 1, 2021) Neurons lack the ability to replicate their DNA, so they’re constantly working to repair damage to their genome.

DNA 77

DNA Genome Genomics Genetics 77

STAT News

JANUARY 16, 2023

But bits of tumor DNA adrift in a patient’s blood are an important bellwether for whether cancer will return — and, as a new study shows, can predict which treatments are likely to work. They’re far too small to be seen by even the most sophisticated medical imaging device.

DNA 111

DNA Scientist Medicine Research 111

Scienmag

MARCH 21, 2022

Wilmington, DE, (MARCH 21, 2022) – A new study from scientists at ChristianaCare’s Gene Editing Institute is advancing the safety and efficacy of using CRISPR gene editing in patient treatments by demonstrating how to identify and evaluate the broad-based biological impact of gene editing on targeted tissues, where the edits are designed to fully disable (..)

Gene Editing 80

Gene Editing Gene Scientist DNA 80

BioTech 365

APRIL 19, 2021

Biotechnology, Pharma and Biopharma News – Research – Science – Lifescience ://Biotech-Biopharma-Pharma: DNA robots designed in minutes instead of days.Someday, scientists believe, tiny DNA-based robots and other nanodevices will deliver medicine inside our bodies, detect the presence of deadly … Continue reading →

DNA 40

DNA Scientist Medicine Research 40

Drug Discovery World

DECEMBER 29, 2023

A new technique to clone and reassemble DNA could simplify and lower the cost of making synthetic chromosomes, according to its creators at University of Southern California (USC) Dornsife. The thing about most synthetic genomics research is that it involves building chromosomes or genomes from scratch using chemically synthesised DNA pieces.

Genome 52

Genome Genomics DNA Scientist 52

Medical Xpress

FEBRUARY 21, 2023

Northwestern Medicine scientists have identified a gene that plays a role in cellular responses to molecular stressors, such as DNA damage and nutrient scarcity, according to findings published in Nature Communications.

Gene 75

Gene DNA Scientist Medicine 75

Scienmag

OCTOBER 13, 2021

LA JOLLA—(October 13, 2021) For the past fifteen years, cancer researchers have been using DNA sequencing technology to identify the gene mutations that cause the different forms of cancer.

Scientist 52

Scientist Gene DNA Genetics 52

Medical Xpress

DECEMBER 15, 2022

Northwestern Medicine scientists have identified disease-causing DNA variants in two genes linked to neurodevelopmental deficits including microcephaly in children, according to findings published in Nature Communications.

Gene 75

Gene DNA Scientist Medicine 75

Scienmag

APRIL 27, 2022

CHAPEL HILL, NC – Inside embryonic cells, specific proteins control the rate at which genetic information is transcribed from DNA to messenger RNA – a crucial regulatory step before proteins are created. Then, organs develop and hopefully function properly.

Scientist 83

Scientist Gene RNA Protein 83

Scienmag

OCTOBER 22, 2020

For scientists, digging into feces provides insights into animal diets and is particularly useful for understanding nocturnal or rare species. When animals eat, prey DNA travels all the way through animal digestive tracts and comes out again. Credit: Illustration by Amy Koehler Poop is full of secrets.

DNA 54

DNA Containment Scientist Bioinformatics 54

The Pharma Data

FEBRUARY 22, 2022

State-of-the-art facility will headquarter research efforts in Boston and New York to accelerate the development of RNA and DNA-based medicines. Adams, vice president of genetic medicine at Lilly and co-director of the Institute. ” The Institute will be headquartered in 334,000 sq.

Genetics 52

Genetics Medicine RNA Scientist 52

Medical Xpress

MARCH 30, 2023

Johns Hopkins Medicine scientists say their 20-year study of more than 200 people with premature aging syndromes caused by abnormally short telomeres, or shortened repetitive DNA sequences at the ends of chromosomes, may upend long-held scientific dogma and settle conflicting studies about how and whether short telomeres contribute to cancer risk. (..)

DNA 75

DNA Scientist Medicine 75

Scienmag

MAY 6, 2021

Jude Children’s Research Hospital scientists have developed a highly efficient method to address a major challenge in biology–identifying the genetic ‘switches’ that regulate gene expression. Credit: St. Jude Children’s Research Hospital St.

Gene Expression 97

Gene Expression Regulation Gene DNA 97

STAT News

OCTOBER 5, 2022

Scientists rely on gene synthesis technologies as a research tool for everything from basic research to vaccine development and drug target identification. Ever since the inception of gene synthesis, there have been concerns about possible misuse of synthetic genes. Read the rest…

Gene 98

Gene DNA Engineer Scientist 98

Scienmag

DECEMBER 29, 2020

Method will help researchers better understand mitochondrial DNA diseases LOS ANGELES — Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a simple, high-throughput method for transferring isolated mitochondria and their associated mitochondrial DNA into mammalian cells.

Scientist 40

Scientist Development DNA Genetics 40

Drug Discovery World

AUGUST 3, 2023

In the first part of this series of articles focused on plant-based medicines, DDW’s Megan Thomas evaluates the use of medical cannabis in drug discovery. Medical cannabis is often a first-thought when regarding plant-based medicines, but there remains public scepticism, arguably due to the regulations relating to the substance.

Medicine 52

Medicine Scientist Production Regulation 52

Scienmag

APRIL 15, 2021

Team of Japanese and European scientists identify a novel genetic mitochondrial disorder by analyzing DNA samples from three distinct families Credit: Fujita Health University DNA ligase proteins, which facilitate the formation of bonds between separate strands of DNA, play critical roles in the replication and maintenance of DNA.

Genetics 105

Genetics DNA Genome Genomics 105

STAT News

MARCH 9, 2023

LONDON — Scientists at this year’s genome editing summit spent Tuesday showing the world just how far CRISPR -based medicines for treating human diseases have come in a decade. Continue to STAT+ to read the full story…

Gene Editing 98

Gene Editing Genome Genomics DNA 98

Scienmag

APRIL 8, 2021

Credit: IRB Barcelona In cancer, personalised medicine takes advantage of the unique genetic changes in an individual tumour to find its vulnerabilities and fight it. Many tumours have a higher number of mutations due to a antiviral defence mechanism, the APOBEC system, which can accidentally damage DNA and cause mutations.

Scientist 53

Scientist DNA Genetics Medicine 53

Scienmag

JANUARY 12, 2021

Researchers have found a simple way to eliminate almost all sequencing errors produced by a widely used portable DNA sequencer, potentially enabling scientists working outside the lab to study and track microorganisms like the SARS-CoV-2 virus more efficiently.

DNA 40

DNA Scientist Research Bioinformatics 40

STAT News

OCTOBER 12, 2022

The scientist flicked on a laser, filling the rat’s brain with blue light. From the outside, this would appear to be a pretty run-of-the-mill neuroscience experiment, except for the fact that the neurons directing the rat to its thirst-quenching reward didn’t contain any rat DNA.

DNA 144

DNA Containment Scientist Medicine 144

STAT News

JULY 28, 2022

In a little-noticed study published earlier this year, scientists from Oregon Health & Science University reported the birth of three mouse pups that had been created with a never-before-used recipe for reproduction.

In-Vitro 98

In-Vitro Research DNA Genetics 98

Scienmag

MAY 28, 2021

The scientists analyzed short fragments of tumor DNA that are circulating in the blood. Credit: Tatjana Hirschmugl A new study exploits the characteristic epigenetic signatures of childhood tumors to detect, classify and monitor the disease.

DNA 96

DNA Genetics Scientist Clinical Trials 96

Scienmag

DECEMBER 8, 2020

Credit: Kim Ratliff, Production Coordinator, Augusta University A key way radiation therapy and chemotherapy work is by making highly lethal double-strand breaks in the DNA of cancer cells.

Protein 76

Protein DNA Scientist Production 76

Scienmag

MAY 10, 2021

Scientists have made major advances in understanding and developing treatments for many cancers by identifying genetic mutations that drive the disease.

DNA 50

DNA Genome Genomics Genetics 50

XTalks

APRIL 23, 2024

Related: Organon’s Commitment to Addressing Contraceptive Deserts The Role of DNA Mapping and Data Mining Further innovation can be seen in the integration of personal DNA genome mapping into medical care. Mangiofico suggests leveraging AI to streamline these processes.

DNA 59

DNA Genome Genomics Pharmacy 59

Drug Discovery World

NOVEMBER 7, 2022

Genomic healthcare data is critical to identify disease risk, ancestry, traits and response to medicines and aids in the development of new targeted therapies – precision medicines. The scientists said the results support the use of WGS as a standard diagnostic tool within routine clinical practice and the study 3. .

Genome 98

Genome Genomics Development Genetics 98

Drug Discovery World

OCTOBER 6, 2023

In celebration of the Nobel Prize for Medicine going to two of the early proponents of mRNA technology for creating therapeutics, Katalin Karikó and Drew Weissman, this week our round-up highlights the importance of genetics, genomics and gene editing in drug discovery.

Drugs 52

Drugs Gene Editing Genome Genomics 52

Scienmag

APRIL 5, 2021

Study shows that tumor-suppressor protein p53 brings speckles and DNA together to boost gene expression PHILADELPHIA – A team led by scientists at the Perelman School of Medicine at the University of Pennsylvania has illuminated the functions of mysterious structures in cells called “nuclear speckles,” showing that they can work in (..)

Gene 42

Gene Gene Expression DNA Protein 42

Drug Discovery World

NOVEMBER 8, 2022

Researchers from the University of Missouri analysed the DNA sequences of more 200 strains of monkeypox virus spanning multiple decades, from 1965, when the virus first started spreading, to outbreaks in the early 2000s and again in 2022. . “By

Drugs 52

Drugs DNA Vaccination Vaccine 52

Scienmag

FEBRUARY 11, 2021

11, 2020 -Scientists have developed an affordable, downloadable app that scans for potential unintended mistakes when CRISPR is used to repair mutations that cause disease. The app reveals potentially risky DNA […].

Gene 73

Gene Gene Therapy DNA Scientist 73