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Genetic biomarkers could personalise therapy for TNBC

Drug Discovery World

A new study has shed light on the genetic messages encoded by genes within ‘triple negative’ breast cancers (TNBC), and shows they could predict response to chemotherapy. The presence of these biomarkers could be used to accelerate the development of more personalised treatments for triple negative breast cancers.

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Treatment Reverses Young Man’s Type 1 Diabetes. Will It Last?

The Pharma Data

Lisa Forbes — his doctor and co-author of a letter describing his case in the Oct. 8 issue of the New England Journal of Medicine — stopped short of calling the drug a cure for type 1 diabetes. This patient had a genetic mutation that ruxolitinib is known to work on. At 17, he was diagnosed with type 1 diabetes.

Insulin 52
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Health at every size – making medicine weight inclusive

pharmaphorum

UK-based doctor, Dr Natasha Larmie is on a mission to make medicine weight inclusive. We would never use such a useless screening tool in any other area of medicine, so why do we still use BMI?” For most doctors that bias is implicit, she says. ” The next issue is patients then begin to avoid seeing the doctor.

Medicine 104
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Research Roundup: Blood Test for Severe COVID-19 and More

The Pharma Data

Researchers at Washington University School of Medicine in St. They are now working to identify what genetic aberrations are causing ALS in about half of the Maltese patients. They believe this is key to understanding how aggressive prostate cancer subtypes and neuroendocrine prostate cancer (NEPC) develop after hormonal therapies.

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CAPTIVATE Study Shows an IMBRUVICA® (ibrutinib) Plus VENCLEXTA®/VENCLYXTO® (venetoclax) Chemotherapy-Free Combination Has Potential to Provide Remission After Fixed-Duration Treatment for Chronic Lymphocytic Leukemia (CLL)

The Pharma Data

IMBRUVICA is the only FDA-approved medicine in WM and cGVHD. IMBRUVICA was one of the first medicines to receive FDA approval via the Breakthrough Therapy Designation pathway. Tell your healthcare provider about all the medicines you take, ?including with certain other medicines may affect how IMBRUVICA ® ?works

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The Obesity Pandemic: What can we do about it?

Delveinsight

An Individual’s metabolic activity, genetics, environmental factors, behavior, and hormones can supposedly cause overweight and obesity. Apart from calorie and physical activity, some of the genetic and social factors also influence the prevalence of obesity. What causes obesity? Obesity Pandemic.

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Fat Shrinking Signal

The Pharma Data

Millions of Women Over 30 Suffer From This Hidden Hormonal Disorder That Keeps You Overweight, Weakens Your Heart, & Starves Your Brain. And it led to a SHOCKING revelation that saved my life, you see… This Hidden Hormonal Defect Makes Weight Loss Impossible And Is the REAL Reason You’re Frustrated & Struggling.