Scienmag

MAY 16, 2022

Just as it’s hard to understand a conversation without knowing its context, it can be difficult for biologists to grasp the significance of gene expression without knowing a cell’s environment.

Gene Expression 97

Gene Expression Engineer Gene Development 97

Scienmag

MARCH 19, 2021

Credit: Thomas Gorochowski In a recent study led by the University of Bristol, scientists have shown how to simultaneously harness multiple forms of regulation in living cells to strictly control gene expression and open new avenues for improved biotechnologies.

Gene 75

Gene Gene Expression Engineer Regulation 75

Drug Discovery World

FEBRUARY 27, 2024

BS: Genetic tuning, also called epigenetic editing, actively manipulates the epigenetic machinery to influence gene transcription. Orchestrating the naturally occurring conductors of gene expression can shift the functional state of cells and alter gene expression.

Gene Expression 59

Gene Expression DNA Genetics Gene 59

XTalks

AUGUST 5, 2020

Visium Spatial Gene Expression Solution. To address challenges associated with loss of spatial context, 10x Genomics has developed the Visium Spatial Gene Expression solution, which enables answering biological questions in the context of tissue using an unbiased gene expression approach.

Gene Expression 112

Gene Expression Development RNA Drugs 112

Drug Discovery World

AUGUST 1, 2023

Partnerships Earlier this year cell-engineering company MaxCyte signed a strategic platform license (SPL) with biotechnology company Catamaran Bio. The agreement will see Catamaran gain access to MaxCyte’s technology platforms which enable the complex engineering of cells.

Drugs 52

Drugs Gene Expression Engineer Gene 52

Scienmag

NOVEMBER 26, 2020

For the first time, researchers describe how Rho protein really stops gene expression COLUMBUS, Ohio – New research has identified and described a cellular process that, despite what textbooks say, has remained elusive to scientists until now – precisely how the copying of genetic material that, once started, is properly turned off.

Gene Expression 54

Gene Expression Genetics Protein Gene 54

pharmaphorum

JANUARY 13, 2022

The UK-headquartered pharma is buying into a drug discovery platform developed by Boston, US biotech Scorpion Therapeutics, paying $75 million upfront to get the ball rolling on the partnership, with undisclosed option fees and milestone payments also on offer.

Protein 59

Protein Gene Expression Regulation Gene 59

Drug Discovery World

DECEMBER 12, 2022

Dr Ramakrishnan, who holds a Bachelor of Biotechnology and Biochemical Engineering from the University of Kerala in India, presented a proposal examining microbiome-based therapeutics for asthma. . This work is a stepping stone toward engineering these cells in even smarter ways so they work better, for longer, and in more cancer types.”.

Drugs 52

Drugs Gene Editing Genome Genomics 52

pharmaphorum

JANUARY 29, 2021

Since that discovery, a flurry of gene-editing focused biopharma companies have launched – including Intellia Therapeutics, CRISPR Therapeutics, Caribou Biosciences and Mammoth Biosciences – and the first drug therapies based on the technology are now in human testing for diseases like cancer.

Gene Editing 145

Gene Editing Gene Gene Therapy In-Vivo 145

XTalks

MARCH 22, 2021

The biotech acquisition will also see Takeda getting Maverick’s TAK-280 (MVC-280), an immunotherapy designed to treat patients with B7H3-expressing solid tumors which is expected to enter the clinic later this year. Both of Biotheranostics’ diagnostics are PCR-based gene expression tests.

Life Science 110

Life Science Development Marketing Gene Expression 110

Roots Analysis

AUGUST 31, 2023

The two types of gene regulation have been discussed below: Positive Gene Regulation: Activator is a protein molecule that helps to initiate a positive gene regulation. When activator binds to the operon, it either speeds up or permits gene expression.

Gene 40

Gene Gene Therapy Gene Expression Regulation 40

The Pharma Data

JANUARY 19, 2021

Fulcrum’s proprietary product engine identifies drug targets which can modulate gene expression to treat the known root cause of gene mis-expression.

Gene Expression 40

Gene Expression Containment Genetics Sales 40

Drug Discovery World

JUNE 30, 2023

With 43 authors, this study brought together leaders in computational biology, engineering, medicine, autism and the microbiome who hailed from institutions in North America, South America, Europe and Asia. Analysis identified autism-specific metabolic pathways associated with particular human gut microbes.

Gene Expression 52

Gene Expression Gene Engineer Containment 52

Drug Discovery World

NOVEMBER 15, 2022

The brainchild of multidisciplinary experts in computer science, physics, engineering, and biology, the field of synthetic biology has not only rapidly progressed in the last few decades but it’s also becoming more accessible and cost-effective. Synthetic libraries for antibody drug discovery . This approach has been around for a while.

DNA 98

DNA Drugs Antibody Engineer 98

XTalks

MAY 4, 2021

These modifications regulate gene expression without changing the sequence or structure of DNA. Now we have a simple tool that can silence the vast majority of genes,” said Jonathan Weissman, PhD, Whitehead Institute member, co-senior author of the new paper and a former UCSF faculty member in a statement from UCSF. “We

DNA 98

DNA Gene Gene Silencing Genome 98

Drug Discovery World

JANUARY 23, 2023

Increasing interest in CRISPR-Cas gene editing systems over recent years has delivered innovative developments in precision genome engineering technologies, holding enormous potential for applications across the healthcare sector. The success of base editing has led to rapid advances toward commercialisation and clinical application.

Gene Editing 52

Gene Editing Gene Engineer DNA 52

XTalks

MAY 4, 2021

These modifications regulate gene expression without altering the sequence or structure of DNA. Now we have a simple tool that can silence the vast majority of genes,” said Jonathan Weissman, PhD, Whitehead Institute member, co-senior author of the new paper and a former UCSF faculty member in a statement from UCSF. “We

DNA 52

DNA Gene Gene Silencing Genome 52

Roots Analysis

OCTOBER 22, 2023

Coding RNAs include messenger RNA (mRNA) and short interfering RNA (siRNA), which encode proteins and silence gene expression, respectively. It is important to highlight that IVT mRNAs are structurally similar to natural mRNAs and can be used to express proteins through genetic engineering.

RNA 40

RNA Protein Genetics Gene Expression 40

Drug Discovery World

OCTOBER 17, 2022

Data lakes served this same purpose, but while the idea was good, the results of search engines were often disappointing. For example, GEO, the gene expression omnibus database, has been collecting gene expression and functional genomics datasets and making them available to the public for more than 20 years.

Marketing 52

Marketing Scientist Gene Expression Drugs 52

Drug Discovery World

FEBRUARY 6, 2023

RNA-Sequencing (RNA-Seq) is a revolutionary technology that enables researchers to assess gene expression changes in thousands of genes over time. For example, we recently collaborated with two sequencing laboratories to determine optimal parameters for RNA-Sequencing (RNA-Seq) in the context of a vaccine clinical trial.

Big Data 52

Big Data RNA Bioinformatics Vaccination 52

Drug Discovery World

DECEMBER 15, 2022

Recent advances in gene editing technologies are extremely encouraging, with simple gene modifications becoming routine in animal models. Researchers are identifying and engineering nucleases to improve specificity and developing new techniques such as base editing and prime editing to mitigate off-target chromosomal damage.

Gene Editing 52

Gene Editing Gene In-Vivo Genome 52

The Pharma Data

DECEMBER 27, 2020

STP705 is a small interfering RNA (siRNA) therapy that leverages a dual-targeted inhibitory property and polypeptide nanoparticle (PNP)-enhanced delivery to knock down both TGF-beta1 and COX-2 gene expression. GA Depot is a long-acting injection of the approved Glatiramer Acetate products (Copaxone and its generic formulations).

Trials 52

Trials Antibody Gene Therapy Clinical Trials 52

XTalks

DECEMBER 24, 2020

While technologies such as fluorescence-activated cell sorting (FACS) have allowed for profiling intracellular and cell surface markers in single cells, analyzing gene expression at the single cell level was previously not possible. The first step in most single-cell analysis techniques involves the isolation of individual cells.

Life Science 111

Life Science Vaccination Vaccine Gene 111

The Pharma Data

MAY 13, 2021

Journal of Food Engineering. Opiate-like effects of sugar on gene expression in reward areas of the rat brain. Raghavendra SN, Ramachandra SSR, Rastogi NK, Raghavarao KSMS, Kumar S, Tharanathan RN. Grinding characteristics and hydration properties of coconut residue: A source of dietary fiber. 2006;72(3):281-286. 2004.12.008. .

Insulin 52

Insulin Production Hormones Medicine 52