BioPharma Reporter

MARCH 2, 2021

The gene-editing and genome-engineering company, eGenesis, today announced the completion of a US$125m Series C financing round.

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Scienmag

FEBRUARY 25, 2021

Publication in Science Credit: David Porubsky, University of Washington In 2001, the International Human Genome Sequencing Consortium announced the first draft of the human genome reference sequence. This reference, however, […].

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Genome Genomics Genome Project Genetics 60

Scienmag

APRIL 26, 2021

. — In October of 2020, Jennifer Doudna and Emmanuelle Charpentier were awarded the Nobel Prize in chemistry for their discovery of an adaptable, easy way to edit genomes, known as CRISPR, which has transformed the world of genetic engineering.

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pharmaphorum

OCTOBER 4, 2022

AstraZeneca’s rare disease firm Alexion is set to expand its genomic medicine portfolio with the acquisition of gene editing specialist LogicBio Therapeutics, in a deal worth approximately $68 million.

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Gene Editing Gene Genome Genomics 62

Scienmag

FEBRUARY 21, 2021

‘Exploring one of the biggest challenges facing genomics today – understanding genetic variants’ SEATTLE (February 22, 2021) – Global experts performing leading edge research in precision medicine, functional genomics, protein science, and variant interpretation and prediction will share their expertise and insights April 5-7 (..)

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Scienmag

OCTOBER 6, 2021

Researchers at the Centre for Genomic Regulation (CRG) and Pulmobiotics S.L have created the first ‘living medicine’ to treat antibiotic-resistant bacteria growing on the surfaces of medical implants. Credit: María Lluch/CRG Researchers at […].

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Drug Discovery World

MAY 5, 2023

Eterna Therapeutics, a life science company focused on mRNA cell engineering, has acquired Exacis Biotherapeutics’ immuno-oncology platform. Eterna plans to use Exacis’ platform to develop engineered cell therapies containing genomic edits designed to enhance their performance.

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pharmaphorum

OCTOBER 14, 2022

The proceeds are to advance Odyssey’s precision immunomodulator and oncology medicine portfolio. There is also a functional genomics platform for novel target discovery. We look forward to seeing Odyssey work toward achieving their mission of delivering life-enhancing medicines to patients in need,” she continued.

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BioTech 365

NOVEMBER 2, 2020

Addition of CRISPR and RNAi offerings to complement PerkinElmer’s life sciences and applied genomics solutions, with future opportunities to improve cell based discovery for precision medicine WALTHAM, Mass.–(BUSINESS –(BUSINESS WIRE)–PerkinElmer, Inc.

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Scienmag

JANUARY 13, 2021

To discover these associations, researchers need to compare the genomes of many individuals at millions of genetic locations or markers, and therefore require cost-effective genotyping technologies. A new statistical method, developed […].

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Drug Discovery World

FEBRUARY 27, 2024

CAR-T Therapies have revolutionised the field of personalised medicine, especially in oncology. Epigenetic editing can also make regions of the genome more accessible, thereby upregulating the region’s expression. These factors can be harnessed to improve CAR T-cell engineering.

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Gene Expression DNA Genetics Gene 59

pharmaphorum

JANUARY 29, 2021

Genome editing is an exciting but still nascent field, and companies in the area face as many obstacles as they do opportunities. ZFPs can be engineered to make zinc finger nucleases, or ZFNs, which are proteins that can be used to edit genomes by knocking select genes in or out to specifically modify DNA sequences.

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Pharmaceutical Technology

FEBRUARY 23, 2023

Moderna Genomics general manager and chief scientific officer Eric Huang said: “Through our collaboration with Life Edit, we hope to harness the power of gene editing technologies as part of our broader research and development engine, helping to advance our mission and deliver on the promise of mRNA.”

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Drug Discovery World

JUNE 22, 2023

Evox Therapeutics has purchased Codiak Biosciences engEx-AAV technology platform, including all intellectual property rights, and exclusive access to certain engineering and manufacturing rights.

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Gene Therapy Gene Editing Drug Delivery Gene 52

Pharmaceutical Technology

MARCH 8, 2023

The new technologies will also overcome the manufacturing bottlenecks in delivering advanced engineered cell products. Its focus areas include human systems, precision diagnostics, data sciences, next-generation biomanufacturing, and genomic medicines. The University of Pennsylvania Immunotherapy Richard W.

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Pharmaceutical Technology

JUNE 5, 2023

Social engineering attacks will rise, in addition to phishing, smishing and deepfake attacks. There is also a debate as to how genomic information should be protected,” he adds. Genomic data plays a central role in the future of the field, especially as new cell therapies and more personalised medicine comes of age.

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Drug Discovery World

OCTOBER 5, 2023

Experts and thought leaders in cancer research, precision medicine and immunotherapy will describe the latest research and the role of technology to help discover targets, develop cancer therapeutics and vaccines and, get to market faster. More to be announced.

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Scienmag

SEPTEMBER 15, 2020

15, 2020 — Initial findings reported by the Arizona COVID-19 Genomics Union (ACGU) suggest that following Arizona’s first reported case of COVID-19 in late January, the state experienced no cases that went undetected […]. — Sept.

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The Pharma Data

DECEMBER 17, 2020

An Fc-engineered monoclonal antibody targeting the HER2 oncoprotein, MARGENZA offers hope for patients who have received two or more prior anti-HER2 regimens, with at least one being for metastatic disease. The new two-hour infusion time was previously approved by the European Medicines Agency (EMA) in May 2020.

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Drug Discovery World

NOVEMBER 30, 2023

Kimryn Rathmell has been chosen as the 17 th director of the National Cancer Institute (NCI), bringing her experience as leader of the Department of Medicine at the Vanderbilt University Medical Center and Physician-in-Chief at the Vanderbilt University Adult Hospital and Clinics.

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Drug Discovery World

FEBRUARY 6, 2024

Companies leading the way There are a number of companies leading the charge in applying innovative technologies, particularly artificial intelligence (AI) and machine learning (ML), to the search for new medicines. Relation Therapeutics, which uses high-resolution biology, ML and clinical insights to discover transformational medicines.

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Scienmag

APRIL 28, 2021

April 28) – The University of Washington’s School of Medicine Brotman Baty Institute for Precision Medicine is collaborating with Illumina, Inc. Supporting families of children with developmental differences SEATTLE and GAITHERSBURG, MD. Nasdaq: ILMN) and GeneDx, Inc.,

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The Pharma Data

JANUARY 24, 2021

Bond joins Notch from Kite, where he most recently served as Vice President of Cellular Engineering. Dr. Bond has extensive experience in the discovery and development of adoptive cell therapies, monoclonal antibodies, and cellular engineering and genome editing. ” Chris Bond , Ph.D.,

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Drug Discovery World

APRIL 13, 2023

The Biology Unveiled track will feature scientific sessions focusing on the hot topic of personalised medicine, along with advances in the uses of CRISPR and vessels-on-a-chip. Sixteen speakers will showcase the latest drug discovery research in this vast topic based on tiny particles.

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Scienmag

OCTOBER 27, 2020

In the world of rare genetic diseases, exome and genome sequencing are two powerful tools used to make a diagnosis. A recent addition to the toolkit, RNA sequencing, has been demonstrated to help researchers narrow down disease candidate variants identified first on exome and genome sequencing.

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Scienmag

AUGUST 11, 2020

Assessing clinical data across the lifespan identified the impact of genetic epilepsies on affected children’s lives Philadelphia, August 11, 2020 – A team of researchers at Children’s Hospital of Philadelphia (CHOP) affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) further bridged the gap between genomic information (..)

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Drug Discovery World

DECEMBER 19, 2023

The post SLAS2024 Ignite Theater: Will you be there? appeared first on Drug Discovery World (DDW).

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Drug Discovery World

DECEMBER 12, 2022

The announcement followed the signing of deals to make new medicines available across the country. . Dr Ramakrishnan, who holds a Bachelor of Biotechnology and Biochemical Engineering from the University of Kerala in India, presented a proposal examining microbiome-based therapeutics for asthma. .

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The Pharma Data

MARCH 31, 2023

Better understanding of enzymes and their functions would be a boon for research in genomics, chemistry, industrial materials, medicine, pharmaceuticals and more. Woese Institute for Genomic Biology at Illinois. ” The researchers will publish their findings in the journal Science and make CLEAN accessible online March 31.

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Drug Discovery World

MAY 16, 2023

New South African company NewBiologix has launched with the aim of developing a proprietary and breakthrough platform for the advanced engineering of cell lines used to manufacture gene and cell therapies.

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Drug Discovery Today

APRIL 22, 2020

Cambridge, UK, and Brisbane, CA, 21 April 2020 Mogrify Ltd (Mogrify®), a UK company aiming to transform the development of cell therapies by the systematic discovery of novel cell conversions, and Sangamo Therapeutics (Sangamo) (Nasdaq: SGMO), a genomic medicine company, today announced that they have executed a collaboration and exclusive license (..)

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Cloudbyz

MARCH 6, 2024

Personalized Medicine: Biologics offer the potential for personalized treatment approaches by taking into account individual variations in genetics, immune responses, and disease characteristics. The rise of biologics represents a watershed moment in the history of medicine, ushering in a new era of precision, efficacy, and personalized care.

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Drug Discovery World

DECEMBER 15, 2022

Vor Bio, a clinical-stage cell and genome engineering company, has announced initial clinical data from VBP101, its Phase I/IIa multicentre, open-label, first-in-human study of tremtelectogene empogeditemcel or “trem-cel” (formerly VOR33) in patients with acute myeloid leukemia (AML). . Official comments .

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Drug Discovery World

OCTOBER 3, 2022

The role of AI and automation in personalised medicine: How can AI help in the post drug discovery process. She has extensive R&D and commercial experience in automated liquid handling and high throughput analytical techniques, spanning both genomics and drug discovery applications. The sustainable lab. in Chemistry and D.Phil.

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pharmaphorum

MARCH 7, 2022

The approach combines phenotypic screening, proteomics, and genomics-based technologies with machine learning-powered analysis of data, avoiding the use of standard growth inhibition assays which can be slow and may miss potentially promising mechanisms. million deaths a year, according to the 2019 Gram Report. Dr Zemer Gitai.

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Bacteria Drugs Genome Genomics 137

pharmaphorum

SEPTEMBER 16, 2022

Verily’s Immune Profiler platform is “a discovery engine consisting of proprietary immune profiling lab workflow, growing multi-omic database, and advanced analytical tools”. Kim recognised then, he said, that better tools for medicine needed to be developed, and that they still do. What, then, is the solution?

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The Pharma Data

SEPTEMBER 1, 2021

With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation. ” The new findings are published online Sept.

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