XTalks
MAY 12, 2021
In this episode, Ayesha discusses a new tool that uses CRISPR to modulate gene expression without editing DNA sequences. Dubbed “CRISPRoff,” the technology targets the epigenome to silence genes involved in diseases, with applications in cancer, AML and other conditions with a heritable component.
XTalks
AUGUST 5, 2020
The detailed complexity of these processes can be captured by creating models that combine correlates of gene and protein expression, providing insight into the molecular composition of tissues. Visium Spatial Gene Expression Solution. Feature barcoding using gel beads. Leading Innovations in Single Cell Technology.
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Drug Discovery World
JULY 15, 2022
The first complete, gapless sequence of a human genome was published 1 April 2022 in a special issue of the journal Science 1. While The Human Genome Project mapped about 92% of the human genome two decades ago, sequencing the last 8% of the genome proved highly challenging.
XTalks
AUGUST 12, 2020
Work from different fields, including evolutionary biology, suggest that there are four fundamental building blocks of life: DNA and RNA (nucleic acids), protein, lipids and sugars.
XTalks
MAY 4, 2021
These modifications regulate gene expression without changing the sequence or structure of DNA. The tool could also prove to be safer than conventional CRISPR-based gene therapies as it does not involve DNA editing, and thus would not cause potentially harmful off-target genomic changes. Epigenetic Editing with CRISPR.
XTalks
MAY 4, 2021
These modifications regulate gene expression without altering the sequence or structure of DNA. The tool could also prove to be safer than conventional CRISPR-based gene therapies as it does not involve DNA editing, and thus would not cause potentially harmful off-target genomic changes. Epigenome Editing with CRISPR.
XTalks
MARCH 7, 2024
A new workflow from BioSkryb Genomics merges extensive data from whole genome sequencing (WGS) and the focused insights gained from small, targeted panels that emphasize druggable targets. Through this, researchers can pinpoint breast cancer cell types and their phenotypic states.
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