Scienmag

MARCH 29, 2021

Tissue collection at NOAA Fisheries lab helps reveal genetic distinction Credit: Mansur/WCR Bangladesh New genetic analysis and years of painstaking research has revealed that one of the world’s most endangered marine mammals is actually two species rather than one, as scientists had long assumed.

Genetics 86

Genetics Genetic Analysis Scientist Research 86

The Pharma Data

JANUARY 7, 2021

The study — described as the most diverse genetic analysis for prostate cancer ever — included men of African, Asian, Hispanic and European ancestry. That is evidence that genetics play some role in the differences in frequency of prostate cancer among various racial groups, the study authors said.

Gene 52

Gene Genetics Genome Genomics 52

Scienmag

FEBRUARY 11, 2021

A new largescale genetic analysis has found biological mechanisms that contribute to making people more susceptible to muscle weakness in later life, finding that diseases such as osteoarthritis and diabetes may play a large role in susceptibility.

Genetic Analysis 40

Genetic Analysis Genetics Research Gene 40

The Pharma Data

SEPTEMBER 3, 2020

Comparing four separate forms of the disease, they found that samples of the most aggressive form, known as metastases-like primary tumours, saw changes in activity of 74 immune-related genes, compared with changes in only 12 in the more benign insulinoma-like tumours.

Research 52

Research Genetic Analysis Gene Scientist 52

Delveinsight

FEBRUARY 25, 2021

Beam Therapeutics has taken over a startup whose technology could proffer the biotech’s genetic medicines to more tissues in the body, widening the potential to approach more diseases. The gene-editing technologies, which have reached the clinic, CRISPR, zinc finger nucleases, and TALENs, make their edits by nicking DNA at the target site.

DNA 52

DNA In-Vivo Genetics Medicine 52

pharmaphorum

NOVEMBER 16, 2022

“The risk profile of developing AMD has been studied for years,” he said, “and more than 50% of a given individual’s risk profile is dependent on their genetics. So, pegcetacoplan blocks an inflammatory pathway that appears to be central for geopathic genesis based on extensive genetic analysis,” Dr Wykoff concluded.

Genetics 103

Genetics Trials Clinical Trials Clinical Trials 103

The Pharma Data

APRIL 8, 2022

Genetic analysis revealed that the mechanical strain had activated molecular pathways related to immune defense and multiple antiviral genes, and these activations were reversed when the cyclical stretching was stopped.

Immune Response 52

Immune Response In-Vivo Genetic Analysis Research 52

Drug Discovery World

FEBRUARY 28, 2023

Now, given the extraordinary success of the Covid-19 vaccines, the mRNA platform may bring renewed hope as researchers explore its potential to advance medicines for rare diseases. Interestingly, at least 80% of all rare diseases originate from monogenic mutations, meaning that they arise from mutations in a single gene 4.

Genetics 52

Genetics Genetic Analysis Vaccination Vaccine 52

pharmaphorum

APRIL 5, 2022

Genetic analysis of tumours can reveal mutations that are fuelling cancers growth, some of which can be targeted with treatment, they note. They then used the AI to predict sensitivity to drug combinations, using 21 different two-drug combinations in lung cancer cells with different gene faults, such as mutations in EGFR and KRAS.

Protein 67

Protein Genetic Analysis Genome Genomics 67

XTalks

MARCH 7, 2024

The company’s ResolveOME multiomic workflow provides a comprehensive multiomic analysis of breast cancer through the use of exome hybrid capture alongside a single-cell workflow for single-cell resolution of single nucleotide variants (SNVs), copy number alterations and gene expression signatures, coupled with a targeted protein panel.

Hormones 115

Hormones Genetics Genome Genomics 115

Drug Discovery World

JUNE 14, 2023

BCA members also operate the BCA Advanced Therapies Network which is a diverse, fully integrated portfolio of blood, cell, gene and tissue materials that support the development and delivery of advanced therapies. One example we are following with anticipation are the two FDA approvals for the first gene therapies for sickle cell disease.

Manufacturing 52

Manufacturing Production Gene Therapy Development 52

Drug Discovery World

APRIL 21, 2023

SLAS Student Poster Award The SLAS Student Poster Award recognises innovative research by students, graduate students, post- doctoral associates and junior faculty (less than four years in first academic appointment) who are chosen to present a poster during SLAS Europe 2023.

Doctors 52

Doctors Doctor Genetics In-Vitro 52