article thumbnail

Genetic analysis links obesity to higher rheumatoid arthritis risk

Scienmag

An analysis of genetic data collected from more than 850,000 individuals of European ancestry has found a link between obesity-related genes and rheumatoid arthritis.

article thumbnail

After Stillbirth, New Genetic Analyses May Give Parents Answers

Scienmag

12) — Columbia researchers have uncovered an array of new genes that cause stillbirth, significantly increasing the understanding of the condition’s genetic foundations. The findings suggest that genetic analysis could be used to counsel parents who have previously experienced stillbirth and to unlock new human biology.

Insiders

Sign Up for our Newsletter

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

article thumbnail

Genes Help Explain Role of Race in Prostate Cancer Risk

The Pharma Data

. “The potential utility of this is that it can be used to define men who are at elevated risk of developing prostate cancer,” said lead author Christopher Haiman, professor of preventive medicine at Keck School of Medicine at the University of Southern California (USC) in Los Angeles.

Gene 52
article thumbnail

New research identifies biological causes of muscle weakness in later life

Scienmag

A new largescale genetic analysis has found biological mechanisms that contribute to making people more susceptible to muscle weakness in later life, finding that diseases such as osteoarthritis and diabetes may play a large role in susceptibility.

article thumbnail

Immunotherapies could target aggressive pancreatic cancer, research indicates

The Pharma Data

Comparing four separate forms of the disease, they found that samples of the most aggressive form, known as metastases-like primary tumours, saw changes in activity of 74 immune-related genes, compared with changes in only 12 in the more benign insulinoma-like tumours.

article thumbnail

Beam makes USD 120M bet; GRAIL and Quest announce the collaboration; Brain organoids mimic infant’s brains; Improvement in T cells to kill cancer

Delveinsight

Beam Therapeutics has taken over a startup whose technology could proffer the biotech’s genetic medicines to more tissues in the body, widening the potential to approach more diseases. Cambridge, Massachusetts-based Beam aims to make more precise edits with genetic medicines, which employ base-editing.

DNA 52
article thumbnail

Hope in sight with Apellis’ pegcetacoplan OAKS/DERBY results for GA

pharmaphorum

The risk profile of developing AMD has been studied for years,” he said, “and more than 50% of a given individual’s risk profile is dependent on their genetics. So, pegcetacoplan blocks an inflammatory pathway that appears to be central for geopathic genesis based on extensive genetic analysis,” Dr Wykoff concluded.