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Modernizing cell culture processes for the next wave of genomic medicine

Pharmaceutical Technology

The field of genomic medicine has reached a true turning point. With scientists fervently developing mRNA vaccines, nucleic acid therapeutics, and viral vector-based gene therapies, clinicians are set to have a growing number of tools available to treat a wide range of conditions, from infectious diseases to genetic disorders and more.

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New COVID test doesn’t use scarce reagents, catches all but the least infectious

Scienmag

Addresses major testing need in developing world; also in US, where reagent supplies are again dwindling Credit: Brian Jenkins A major roadblock to large scale testing for coronavirus infection in the developing world is a shortage of key chemicals, or reagents, needed for the test, specifically the ones used to extract the virus’s genetic material, (..)

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New research will allow convenient investigation of human innate immune response to viral infections

Scienmag

(Boston)–Researchers from Boston University School of Medicine (BUSM) report the formation of human cells containing a green fluorescent protein or GFP (one of the most important proteins in biology and fluorescence imaging) genetically fused with two interferon stimulated genes (ISGs), namely Viperin and ISG15.

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New Corona test developed

Scienmag

However, it requires expensive laboratory equipment and global shortages of reagents […]. Evolutionary Anthropology Quantitative real-time polymerase chain reaction (qPCR) is the most widely used diagnostic method to detect RNA viruses such as SARS-CoV-2.

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Next Generation Sequencing (NGS) Library Preparation Kits Market: Current Scenario and Future Potential

Roots Analysis

Advancement in DNA sequencing technologies have resulted in noteworthy developments in various healthcare-related research fields, such as diagnostics and personalized medicine. Moreover, the manual protocols require extensive manipulation, costly reagents and long duration of skilled genomic library production. Concluding Remarks.

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Casting aside CRISPR scissors and making a point with base editors

pharmaphorum

“A recent report indicates that autologous T cells that carry multiple CRISPR-Cas9-mediated genetic modifications designed to improve persistence and efficacy can be safely administered to patients with refractory cancer, providing an important step forward in the use of CRISPR in immune cell therapies”.

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Delivering on the promise of gene editing

Drug Discovery World

Gene editing tools such as zinc finger nucleases, transcription activator-like effector nucleases (TALEN) and clustered regularly interspaced short palindromic repeat (CRISPR) nucleases have been heralded for their enormous potential to treat diseases and genetic disorders. Likewise, Lessard et al. References.