pharmaphorum

FEBRUARY 18, 2021

The South African coronavirus variant may cut the effectiveness of Pfizer/BioNTech’s vaccine by around two thirds, according to a laboratory study. In a response statement Pfizer and BioNTech noted that the COVID-19 vaccine did still provide protection in the lab study.

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pharmaphorum

DECEMBER 21, 2020

Moderna and BioNTech, two rising stars in biotech, were in the limelight this year with their pioneering mRNA vaccines against COVID-19. Just who are these companies and who is behind them, asks Richard Staines. A year ago, the names Moderna and BioNTech were known mainly to those who followed biotech and pharma dealings.

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Vaccination Vaccine Doctors Doctor 92

pharmaphorum

MAY 26, 2022

While many pharma companies are actively working on initiatives to improve diversity in clinical trials, we still have a long way to go. The race to produce a vaccine which could protect the world against COVID-19 brought the topic of diversity in clinical trials, or lack of it, into sharp focus.

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pharmaphorum

JANUARY 6, 2021

Pharma companies are always talking about moving ‘beyond the pill’, and Pfizer’s new brand identity embodies that – it’s decades old pill-like logo has been replaced with a DNA double helix that it says reflects its commitment to breakthrough science. — Tinglong Dai (@TinglongDai) January 5, 2021.

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DNA Branding Vaccination Vaccine 113

Drug Discovery World

JULY 19, 2023

Bioinformatics and genetic sequencing are starting to be placed front and centre of public research programmes as scientists from around the world recognise the substantial benefits of knowledge sharing and resource pooling when it comes to genetic science. The tide has been turning in the worlds of diagnostics and drug development.

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Genome Genomics Bioinformatics Genetics 52

World of DTC Marketing

JANUARY 31, 2021

The venture capitalists funding them are looking for a big payday when a pharma company acquires them. I have been recruited by these companies who promise huge payouts when they are acquired if their drug shows promise in clinical trials. In pharma R&D returns have declined to 1.8 percent—a slight decrease of 0.1

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Pharmaceutical Technology

APRIL 12, 2023

The Association of the British Pharmaceutical Industry (ABPI) also states that “the use of animals in medical research has played and continues to play an essential role in the development of new medicines and vaccines”. The topic of animal testing remains a fiercely contentious topic in the public eye.

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Regulation Vaccination Vaccine Medicine 245

pharmaphorum

SEPTEMBER 18, 2020

But although it was dubbed a “dangerous game”, some companies came out on top… On 6th April 1999, two companies with similar science-based cultures and a shared vision of the pharmaceutical industry came together to form what’s now considered as one of the top ten pharma companies in the world: AstraZeneca.

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XTalks

DECEMBER 20, 2023

Check out this article to learn about the biotech companies that went public this year. The companies include a diverse range engaged in innovative approaches in areas like oncology, genetic medicines, inflammatory diseases, dermatology and cardiorenal therapy. billion in 2022.

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pharmaphorum

AUGUST 23, 2022

With COVID-19 vaccines and therapeutics developed in rapid time, Ben Hargreaves investigates why this has not been the case with the creation of a treatment for Long COVID. Once the scale of the threat was understood, the pharmaceutical industry reacted with a rapidity and agility that allowed vaccines to be developed at a record rate.

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XTalks

OCTOBER 15, 2021

The cell line, called HeLa, laid the foundation for many groundbreaking discoveries, including vaccines for the human papilloma virus (HPV) and polio; drugs for HIV and cancers; gene mapping; IVF treatment; and more recently, for crucial COVID-19 research. Fittingly, it was also used to develop the vaccine against cervical cancer.

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Vaccination Vaccine Gene Mapping Doctors 105

pharmaphorum

JUNE 14, 2022

The innovation that is happening within the Chinese biopharma ecosystem means that frequently Western pharma companies are looking to partner with Chinese firms to bring treatments to the US and Europe. Only last month , the US company Merck agreed to pay a potential $1.4 Evolving regulatory landscape.

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Clinical Trials Clinical Trials Trials Development 98

Pharmaceutical Technology

MARCH 20, 2023

Pharma companies and world health stand to benefit from new technologies, but it’s a tough time to be an investor – and an even tougher one for firms seeking investment. The mRNA technology that enabled the largest and fastest vaccine rollout in history is the tip of the innovation iceberg. Source: GlobalData.

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Gene Therapy Genome Genomics Gene 225

XTalks

JANUARY 15, 2024

Personalized Medicine Driving Targeted Trials In 2022, personalized medicines accounted for 34 percent of all new FDA drug approvals, as reported by the Personalized Medicine Coalition, reflecting a robust industry focus on treatments tailored to individual genetic profiles.

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Clinical Trials Clinical Trials Trials Clinical Research 105

XTalks

DECEMBER 22, 2021

The RNA Revolution: From mRNA Vaccines to RNA Editing. RNA, and its protein-generating form messenger RNA (mRNA) discovered in 1961 , has quickly transitioned from being an obscure, finicky molecule that is difficult to work with, to becoming a significant cornerstone of therapeutic innovation in pharma and biotech.

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Life Science RNA Vaccination Vaccine 98

pharmaphorum

SEPTEMBER 7, 2022

Pharma has a great opportunity ahead of it when it comes to conducting representative clinical trials. The industry’s application of mRNA techniques during the pandemic led to the fastest vaccine development in history. But our drug development processes are not perfect. The same is true for Asian and Hispanic populations.

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Clinical Trials Clinical Trials Trials Genetics 97

Drug Discovery World

NOVEMBER 15, 2022

If a pharmaceutical company is racing to identify a new vaccine, for instance, then waiting for three weeks to receive DNA sequences each time can slow down the development process compared to competitors who might have faster timelines.” . The longer the DNA gets, the longer it will take for labs to receive it,” notes Dr Daniels. “If

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DNA Drugs Antibody Engineer 98

Drug Discovery World

SEPTEMBER 28, 2022

Its application in pharma, most commonly in drug discovery, has been steadily growing with global partnerships between tech vendors and pharma companies becoming more commonplace. The AI Drug Development Division is focused on AI-guided design and development of individualised neoantigen vaccines in oncology. .

Pharma Companies 52

Pharma Companies Drugs In-Vivo Genetics 52

Pharmaceutical Technology

MAY 26, 2023

Enzymatic DNA production company Touchlight have augmented its DNA production capabilities with a newly announced expansion to its London facilities. Tripling its production capacity, Touchlight can now manufacture 8kg plasmid DNA, a key component for mRNA gene therapies and vaccines.

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pharmaphorum

APRIL 8, 2021

COVID-19 has been a trial-by-fire showing just how quickly drugs and vaccines can be developed under the right circumstances – but there is much to do to ensure this progress is not lost, said speakers at WIRED Health 2021, including the CEOs of BioNTech and BenevolentAI. . In the UK we have world leading genetic sequencing capabilities.

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Development Drugs Vaccination Vaccine 81

The Pharma Data

DECEMBER 30, 2020

Food and Drug Administration (FDA), noted in December 2020 that he expected the pandemic could “effectively” be ended in 2021 with the launch of the Pfizer-BioNTech and Moderna vaccines. AstraZeneca and University of Oxford COVID-19 vaccine authorization. Johnson & Johnson’s COVID-19 vaccine. Now that in the U.S.

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Vaccination Vaccine Gene Therapy Trials 52

pharmaphorum

SEPTEMBER 1, 2020

This knowledge of genetics and the underlying cause of many diseases, including cancer, has resulted in powerful new drugs. In cancer, the pharma industry has begun producing immunotherapies, which do not act directly against the disease but instead enlist the immune system to fight against malignant tissues.

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Medicine Insulin Pharmacy Drugs 145

XTalks

AUGUST 18, 2021

While infectious disease experts and drug companies have rightfully spent the last 18 months developing therapeutics and vaccines targeting SARS-CoV-2 and COVID-19, another global threat to public health — antimicrobial resistance (AMR) — has, and will continue to, persist until similar direct action is taken. That is, until now.

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Development Bacteria Drugs Vaccination 105

Drug Discovery World

JANUARY 26, 2023

Research into HIV blossomed throughout 2022, with ViiV Healthcare’s combination therapy for HIV-1 gaining approval in Japan; and research moving forward towards a one-time treatment for HIV as well as a vaccine. According to research from Deloitte 1 , the average ROI in R&D for global pharma companies fell to just 1.2%

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Drug Discovery World

OCTOBER 4, 2022

As it stands, there are currently 19 gene therapies approved for clinical use, alongside 18 RNA therapies and 59 non-genetically modified cell therapies, according to the Q2 report by the American Society of Cell & Gene Therapy. This year has seen some major deals announced by big pharma companies.

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Gene Therapy Drugs Gene Manufacturing 52

The Pharma Data

DECEMBER 23, 2020

Given the massive pandemic caused by SARS-CoV-2, a virus with almost identical genetic sequence and similar in pathogenesis to the first SARS virus with persuasive emerging evidence supporting COVID-19’s SARS-CoV-2 induced chronic fatigue is following a similar pattern. See: PLOS ONE ). AIM CEO Thomas K. About AIM ImmunoTech Inc.

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Clinical Trials Clinical Trials Trials Drugs 52

pharmaphorum

MARCH 30, 2021

Alexion is a somewhat unique pharma company in that it focuses almost entirely on rare diseases – and although this is an immensely challenging area to operate in, the company’s senior vice president of its international business, Camilla Harder Hartvig, says it provides an unparalleled “sense of mission”.

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pharmaphorum

DECEMBER 23, 2020

It has been a year dominated by the pandemic and many life sciences research projects were put on hold as big pharma turned its attention to vaccines and therapies. Pharma companies have also made headway in rare diseases as several pipeline projects came to fruition. Rare disease progress.

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XTalks

DECEMBER 29, 2022

Vertex is planning to submit a Biologics License Application (BLA) by the end of the first quarter of 2023 and the company says it is also on track to submit exa-cel to UK and European Union (EU) regulators by the end of the year. As such, most gene therapies in late-stage clinical trials are in oncology or rare disease indications.

Life Science 52

Life Science Gene Therapy Gene Manufacturing 52

Drug Discovery World

JANUARY 24, 2023

In the near term, as we’ve seen in oncology, we will benefit from new access to important genetic and biological information to not only select patients who will best respond to test therapies, but also more accurately measure the effect of a test therapy in a disease.”

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Clinical Trials Clinical Trials Drugs Trials 97

Drug Discovery World

APRIL 27, 2023

Dr Mansley also comments that the multitude of biotech and pharma companies in the Greater Boston region means that people regularly move organisations. She said: “When one of our customers leaves a company and moves to a new one up the street, they often get in touch with us, which helps us grow new business.

Life Science 52

Life Science Drugs Research Gene Splicing 52

XTalks

AUGUST 17, 2020

protein-based biologics) and vaccine treatments. Treatment vaccines : these boost the immune system responses to target cells. A growing area in the immunotherapy space is the development of biological modulators, which are genetically engineered proteins that target specific components of the immune system.

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Protein Engineer Immune Response In-Vivo 98