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Genetic screening before prescribing could benefit millions, study finds

pharmaphorum

Four million UK patients could benefit annually from genetic testing before being prescribed common medicines, according to new research. The goal was to see how many patients are started on new prescriptions each year that could be potentially optimised by genetic testing. Estimating the potential impact of implementing pre?emptive

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Study: Fiber intake reduces cognitive decline risk in older people with apolipoprotein ?4 allele

Medical Xpress

Fiber intake is associated with a lower risk of developing cognitive decline in those old people with the apolipoprotein E ApoE ε4 genotype, regarded as a genetic risk factor linked to the development of Alzheimer's disease.

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STAT+: Pharmalittle: FDA approves a gene therapy for a rare blood disorder; pharmacy chains ordered to pay $650 million over opioid crisis

STAT News

Food and Drug Administration approved a new treatment that delivers a potentially permanent, genetic fix for patients with the inherited blood disorder beta thalassemia — and quite possibly a financial lifeline for its manufacturer, Bluebird Bio , STAT tells us. As always, do keep in touch. We relish your insights and tips.

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US to procure 3.2 million doses of Covid-19 vaccine from Novavax

Pharmaceutical Technology

A protein-based vaccine, NVX-CoV2373 is created from the genetic sequence of the SARS-CoV-2 virus’ initial strain. Following authorisation, the vaccine will be offered for free to jurisdictions, states, federal pharmacy partners and health centres that are federally qualified.

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Natural products with potential efficacy against lethal viruses

Scienmag

Review of the life histories of RNA viruses, their genetics, and the compounds that could disrupt them offers hope for curtailment of future pandemics Credit: Illustration: Jennifer Matthews/Scripps Oceanography Researchers at Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California (..)

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Cell and gene therapies: why advanced medicines call for specialised logistics

Pharmaceutical Technology

Genetic mutations, both germline and acquired, are behind a large proportion of the most debilitating and sometimes life-threatening human diseases. But scientists have struggled to find effective treatments for many of these diseases since the dawn of modern medicine.

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Lipid nanoparticles and mRNA used to treat hereditary blindness

Drug Discovery World

Oregon State University College of Pharmacy scientists have shown that lipid nanoparticles and messenger RNA could treat blindness associated with a rare genetic condition. . We used these peptides to act as zip codes to deliver nanoparticles carrying genetic materials to the intended address within the eye.” .