Drug Discovery World

JANUARY 9, 2023

In this early research, Khalid Shah, Professor of Neurosurgery at Harvard Medical School and Brigham and Women’s Hospital, and colleagues tested the vaccine in an advanced mouse model of brain cancer glioblastoma, with promising results. The findings are published in Science Translational Medicine. . “Our

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Rethinking Clinical Trials

OCTOBER 2, 2023

There are more than 50 organizations with participating in PROTEUS, including clinicians and patient advocates, research and methods organizations, clinical trials groups, funding and government agencies, and universities and health systems. For clinicians and researchers, there was value in showing them. We are pursuing funding.

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Drug Discovery World

NOVEMBER 7, 2022

Scientists have uncovered a critical feature that a promising new class of cancer drugs, known as CELMoDs, needs to be effective. . CELMoDs are designed to attack cancer by binding to a regulatory protein called cereblon, which then triggers the degradation of key cancer-driving proteins. . Understanding the problem.

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Rethinking Clinical Trials

MARCH 1, 2023

They are both approved and used widely in lung cancer, and combining two existing agents is logistically and clinically simpler. S1800A was a Phase II randomized study of ramucirumab plus pembrolizumab versus standard of care for NSCLC patients previously treated with immunotherapy performed within the Lung-MAP platform.

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Rethinking Clinical Trials

OCTOBER 26, 2023

Untreated, chronic Hepatitis C infection leads to liver damage, liver cancer, and death. There are possible clinical research components that would include research on treatment during pregnancy, vaccine development, and implementation model research. Rates are the highest among 20-39-year-olds.

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Rethinking Clinical Trials

FEBRUARY 14, 2024

The study started in June 2016 and ended in June 2022 and ultimately found no difference between the 2 drugs in preventing major CV outcomes and non-cancer death among hypertensive VA patients. The VA IRB determined DCP was a minimal risk study, with less restrictive eligibility criteria and EHR-based safety and outcome monitoring.

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pharmaphorum

DECEMBER 23, 2022

There’s been huge progress in treatments for blood cancer in recent years – but drawbacks of expensive CAR-T cell and injected antibody therapies have led drug developers to look at novel oral therapies as patient-friendly alternatives. These are particularly important in the progression of certain blood cancers.

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pharmaphorum

DECEMBER 23, 2021

Daiichi Sankyo has been granted breakthrough status by the FDA for patritumab deruxtecan, a HER3-targeted antibody-drug conjugate (ADC) in clinical trials for lung cancer. The post FDA gives Daiichi Sankyo’s HER3 drug a breakthrough tag appeared first on. Daiichi Sankyo and AZ are close collaborators in the ADC arena.

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XTalks

AUGUST 19, 2022

XTALKS WEBINAR: How Agile Clinical Trials Unlock Universal Access to Rare Disease Research. Zynteglo’s hefty price tag of $2.8 The FDA also had to weigh the benefit of the therapy against the risk that it may cause cancer. Live and On-Demand: Tuesday, October 4, 2022, at 11am EDT (4pm BST/UK).

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World of DTC Marketing

DECEMBER 13, 2021

OPENING: American cancer patients spent more than $21 billion on their care in 2019. As cancer survival rates rise, so do the price tags of life-saving treatments. Some cancer patients may face out-of-pocket costs of nearly $12,000 a year for one drug. What makes cancer such a financial killer? ScienceNews.com.

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pharmaphorum

APRIL 5, 2022

Immunocore now has approval on both side of the Atlantic for Kimmtrak – the first cancer therapeutic based on T cell receptor (TCR) technology – after getting a green light from the European Commission. Uveal melanoma is a rare cancer of the eye, which in the majority of patients is localised. ” Image by Pexels from Pixabay

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Pharmaceutical Technology

MAY 15, 2023

Innovation S-curve for the pharmaceutical industry Peptide nano-particle conjugates is a key innovation area in the pharmaceutical industry By tagging peptides with nanoparticles, peptide nano-particle conjugates allow enhanced control over their biological behaviour, overcoming intrinsic limitations of the individual materials.

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Drug Discovery World

JUNE 14, 2023

At the American Association of Cancer Research’s Annual Meeting in Orlando, Florida, DDW’s Megan Thomas met with industry experts to learn more about their research and careers in the field of cancer research. But it also makes the research a little bit more complicated.

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Delveinsight

FEBRUARY 25, 2021

The startup spun out of Georgia Tech in 2018 and is based on James Dahlman’s research, a professor in the university’s department of biomedical engineering and school of medicine. GRAIL and Quest collaborate for the cancer blood test. Overall, this could result in a 26% overall reduction in all five-year cancer deaths.

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Delveinsight

FEBRUARY 9, 2021

Deerfield and Dana-Farber Establish Links in USD 130 Million Cancer Research Deal. Deerfield Management has entered into a research agreement with Dana-Farber Cancer Institute to fuel the development of therapeutics and diagnostics for cancer. Breyanzi, BMS’ Blood Cancer CAR-T Therapy Receives FDA Nod.

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pharmaphorum

JANUARY 5, 2021

The FDA’s breakthrough status is for tiragolumab plus Tecentriq is the first for a TIGIT drug, and covers the first-line treatment of patients with advanced-stage non-small cell lung cancer (NSCLC) that expresses high levels of PD-L1. The post Roche nabs breakthrough tag for TIGIT cancer immunotherapy appeared first on.

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XTalks

FEBRUARY 27, 2024

Melanoma is a type of skin cancer often caused by exposure to ultraviolet light, such as that from sunlight or indoor tanning. Despite accounting for only about one percent of all skin cancers, melanomas make up a significant proportion of cancer-related deaths. The cost is the highest of any cell-based cancer drug in the US.

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XTalks

JANUARY 28, 2022

Kimmtrak has a price tag of $18,760 per vial, which amounts to a weekly dose. Related: Cancer Blood Test Developed by University of Oxford Researchers Can Detect Metastasis. The company is expecting approval from the European Medicines Agency (EMA) soon as it prepares for a European launch in the second quarter of this year.

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The Pharma Data

OCTOBER 21, 2020

21, 2020 — A combination of two “targeted” therapies can beat back a rare form of blood cancer — without the toxic effects of chemotherapy, a new study has found. 22 in the New England Journal of Medicine , could lead to an effective — and chemo-free — treatment for the cancer. WEDNESDAY, Oct.

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The Pharma Data

OCTOBER 21, 2020

21, 2020 — A combination of two “targeted” therapies can beat back a rare form of blood cancer — without the toxic effects of chemotherapy, a new study has found. 22 in the New England Journal of Medicine , could lead to an effective — and chemo-free — treatment for the cancer. WEDNESDAY, Oct.

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The Pharma Data

MARCH 7, 2022

Researchers from the University of Washington School of Medicine in Seattle describe this finding in the journal Cell Reports. The goal of the UW researchers was to find a way to block PRC2 so that only one gene at a time would be affected. Cas9 binds and uses RNA as an address-tag. The location of many of these are unknown.

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Delveinsight

FEBRUARY 23, 2021

The company plans to use the capital to expand its pipeline of protein-based vaccines and biologic cancer therapies utilizing its innovative and proprietary Trimer-Tag technology platform. Libtayo for First-line Advanced Non-small Cell Lung Cancer Subset. LightDeck Diagnostics Gets USD 5.65

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XTalks

DECEMBER 21, 2022

Additionally, advanced technologies like artificial intelligence (AI) and the adoption of digital tools in healthcare are allowing for improved treatments and care, and powerful research insights. These technologies are enabling a broader shift towards the digitalization of healthcare including clinical research.

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XTalks

JANUARY 19, 2024

Radiobiological and Clinical Considerations from CRO and Emerging Biotech Radiopharmaceuticals are medicinal formulations containing radioisotopes that are used in the field of nuclear medicine primarily for the diagnosis and treatment of various diseases, particularly cancer.

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pharmaphorum

JANUARY 21, 2022

“This evolution is leading to additional health benefits and health gains, but they are accompanied by major concerns, as very high price tags raise questions about their affordability.”. By 2026, she said, more than half of all public spend on medicines in Europe will be on cancer drugs for just 2% to 3% of the patient base.

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XTalks

OCTOBER 12, 2022

Features of blood perfusion in the brain detected by MRI now have clinical applications in central nervous system (CNS) cancers, neurodegenerative disease, cerebrovascular disease and demyelinating disease. Figure courtesy of Philips Pharma Solutions, formerly BioTel Research. Anywhere else in the body becomes problematic.

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Drug Discovery World

MAY 22, 2023

But are these price tags a barrier to access? You could thus infer that in some cancers, CAR-T treatment may be the great equaliser, which is why access should be more widespread and costs of goods, and eventually cost of drugs, must be brought down. million per dose.

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Drug Discovery World

OCTOBER 3, 2022

This presentation will consider both of these aspects by discussing the current state of digitisation of scientific research, including how things have changed (or not) since Covid-19, the barriers (and suggested mitigations) to these barriers, and the digitisation requirements of the physical sciences community. Fellowship Programme.

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Delveinsight

DECEMBER 3, 2020

The researchers have been searching for ways to stop the ageing process for millennia; however, such methods remain obscure. The researchers concentrated on the “Yamanaka factors,” which are four transcription factors—Oct4, Sox2, Klf4 and c-Myc. Merck chooses TriNKET cancer immunotherapy program.

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Gene Therapy Gene Antibody Research 52

XTalks

FEBRUARY 11, 2021

Much of the fundamental groundwork for genetics and genomic research was laid in the 20 th century, with significant contributions from women scientists, some of whom worked during times when acceptance of female researchers was not widespread. Here is a profile of some of those brilliant women who helped shape genetics research.

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The Pharma Data

OCTOBER 9, 2021

This designation is predicated on data showing that gantenerumab significantly reduced brain amyloid pillar, a pathological hallmark of Notice, in the ongoing SCarlet RoAD and Marguerite RoAD open- tag extension trials, as well as other studies.

Antibody 52

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Delveinsight

JULY 22, 2020

New Insight/Data For Research. The data collected in the IoT can support medical research. The hospital inventory is equipped with tagged sensors. Connected Contact Lenses, Ingestible Sensors, Cancer Treatment, are some of the other applications of IoT In Healthcare. Research and Development in the IT field.

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pharmaphorum

NOVEMBER 28, 2022

The Linux Foundation AI & Data Foundation will house the software, which will now be available for any researcher to use for similar collaborative-data AI projects. “Researchers can now leverage privacy-preserving and secure federated learning software to drive cutting-edge collaborative medical research. .

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Drug Discovery World

OCTOBER 28, 2022

Over the last seven days we’ve seen discoveries that could lead to new treatments for Covid-19, pancreatic cancer and Epstein-Barr virus, as well as the launch of the UK’s largest health research programme and the innovative application of a Nobel prize-winning chemistry technique. . This week’s top stories: .

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pharmaphorum

OCTOBER 4, 2022

In this article, Ben Hargreaves takes a look at the renewed effort to tackle deaths from cancer in the US through the Cancer Moonshot. Central to the initiative is the aim to gather data from willing participants that can provide greater insights into cancer development and treatment over time. Building a bank.

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Drug Discovery World

NOVEMBER 13, 2023

Thereafter, the following presentations will take place: Melody Shahsavarian, PhD, Digital Biologics Platform, Large Molecules Research, Sanofi, on: ‘Enhancing antibody discovery with generative AI’. Ali Madani, PhD, Founder and CEO, Profluent Bio, on: ‘Protein engineering with large language models’.

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Drug Discovery World

NOVEMBER 9, 2023

Novel platforms This session will begin with chariperson’s remarks from Lars Linden, PhD, Vice President, Head, Biologics Research, Bayer HealthCare, which will be followed by a keynote presentation by Agnieszka Kielczewska, PhD, Director, Research, Antibody Discovery and Screening, Biologics Discovery, Amgen.

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