Pharmaceutical Technology

JUNE 29, 2022

For example, while orphan drug designations have more than doubled in the last decade compared to the previous one, only 16% of therapies with orphan tags have managed to gain FDA approval in some indications.

Drugs 246

Drugs FDA Approval Marketing Development 246

The Pharma Data

MARCH 16, 2022

using SNAP-tag) involves labeling cell proteins with a fluorescent dye, thereby enabling researchers to observe how proteins interact in the living cell and where in the cell they are located. With Spirochrome, he commercialized fluorescent probes for cell biology, while with Covalys, he marketed SNAP-tag and other protein labeling methods.

Protein 52

Protein Scientist Gene Development 52

Roots Analysis

AUGUST 28, 2022

Recent advances in multi-omics approaches, including genomics, transcriptomics, proteomics, metabolomics, cytometry and imaging, in combination with bioinformatics and biostatistics, have been translated into several popular bioanalytical platforms, such as next-generation sequencing (NGS), single-cell analysis, flow cytometry and mass spectrometry.

Genome 52

Genome Genomics RNA Genome Project 52

The Pharma Data

OCTOBER 9, 2021

This designation is predicated on data showing that gantenerumab significantly reduced brain amyloid pillar, a pathological hallmark of Notice, in the ongoing SCarlet RoAD and Marguerite RoAD open- tag extension trials, as well as other studies. Source link: [link].

Antibody 52

Antibody In-Vitro Trials Development 52

Delveinsight

FEBRUARY 25, 2021

Instead of snipping the genome, base editing lets for edits of individual letters in a genetic sequence. DNA hypomethylating agents are epigenetic drugs that eliminate specific chemical tags on DNA, hence turning specific genes on and off and changing the cells’ function.

DNA 52

DNA In-Vivo Genetics Medicine 52

XTalks

FEBRUARY 11, 2021

The Human Genome Project recently marked 20 years since the publication of the first full sets of human genomic sequences, an endeavor that spanned well over a decade. Today, new next-generation sequencing technologies allow for the sequencing of complex genomes within just a day or two.

Genetics 119

Genetics DNA Genome Genomics 119

XTalks

FEBRUARY 27, 2024

Despite high price tags of a couple of million dollars, gene therapy makers say they are working to ensure patients are able to access the treatments through patient assistance programs developed in conjunction with the support of governments. Sarepta hopes to clarify Elvidys’ effectiveness in older children in a confirmatory trial.

Research 59

Research Drugs Gene Therapy Clinical Trials 59

pharmaphorum

DECEMBER 7, 2021

That finding could provide some comfort to Biogen and Eisai, whose recently-approved amyloid-targeting drug Aduhelm (aducanumab) is struggling to gain traction in the market on the back of unconvincing efficacy data, safety concerns and a high price tag.

Drugs 52

Drugs Clinical Trials Clinical Trials Scientist 52

Drug Discovery World

FEBRUARY 9, 2023

While the industry has benefited from that low hanging fruit, including high throughput screening and genomics, leading to substantial discoveries, there is more to be done. It also carries a much higher price tag for failure. I’ll preface this by saying the reasons to shy away from the latest technology are justified.

Drugs 52

Drugs Development Big Data Scientist 52

The Pharma Data

MARCH 20, 2021

professor in Functional Cancer Genomics and Applied. L volumes, even for notoriously difficult liquid classes like the 100% acetonitrile used to store the Tandem Mass Tags (TMT). The MANTIS. liquid handler has also been pivotal. in reducing assay volumes, providing significant cost savings, and again helping to avoid. short supply.

Reagent 52

Reagent RNA Bioinformatics Medicine 52

The Pharma Data

MAY 5, 2021

New variant-hardy AbCellera-Lilly mAb shows utility of viral genomics surveillance ( BioCentury ). AbbVie’s Humira regains top pharma TV spender spot, while sibling brands Rinvoq and Skyrizi tag along ( Fierce ). The weird science of the placebo effect keeps getting more interesting ( Vox ).

Vaccination 52

Vaccination Vaccine Gene Therapy Contract Packaging 52