pharmaphorum

OCTOBER 21, 2021

Analysts were predicting sales of Biogen’s recently approved Alzheimer’s therapy Aduhelm may start to gather a little momentum in the third quarter, but the drug seems to be going into reverse. Vounatsos also insisted that Aduhelm’s price tag has not been a factor discouraging treatment with the drug.

Sales 120

Sales Doctors Doctor Gene Therapy 120

World of DTC Marketing

NOVEMBER 3, 2020

Obesity, lack of exercise, and too much salt are all contributing to a myriad of health issues that are going to drive up healthcare costs. Our healthcare system is set up to treat patients not to prevent bad health habits. We can’t ignore the poor shape of Americans. Employers also bear some responsibility.

Pharma Companies 190

Pharma Companies Scientist Medicine Research 190

XTalks

JUNE 8, 2021

With a price tag of over $2.5 While there are typically two copies of the SMN1 gene in a cell, the numbers of SMN2 can vary, with some people having up to eight copies. Zolgensma Gene Therapy: START Trial. million, Zolgensma is currently the world’s most expensive drug.

Gene Therapy 110

Gene Therapy Gene Protein Trials 110

Rethinking Clinical Trials

AUGUST 22, 2022

We started only looking within the participating health system and sites. We also kept equal focus on follow-up. It was a huge challenge. We used Google Ads and partnerships with some testing clinics. Learn more about COVID-OUT. Learn more about COVID-OUT. pctGR, @Collaboratory1.

Trials 130

Trials Clinical Trials Clinical Trials Insulin 130

pharmaphorum

AUGUST 17, 2020

In this article Joanna Carlish, managing director of financial services at Tag Americas , and Robb DeFilippis, Tag Americas’ managing director, life sciences, go head-to-head to discuss marketing within a regulated industry. Sales calls that now have to start with a phone call are supported by digital and social content straightaway.

Regulation 97

Regulation Marketing Sales Branding 97

XTalks

FEBRUARY 14, 2022

Here are some of this year’s Valentine’s Day food offers from choice-favorite restaurants and fast-food chains, starting with the savory, then the sweet. . This year’s BOGO Chicken Sandwich Combo deal is available starting Valentine’s Day through February 20 on the Popeyes App, the Popeye’s website or at locations nationwide.

Packaging 98

Packaging Packaging Branding Marketing 98

Drug Discovery World

MARCH 2, 2023

A new paper has solved the 20-year mystery of how epigenetic modifications act as traffic lights to control gene expression and could ultimately speed up the development of a new class of epigenetic cancer drugs. But, until now, scientists lacked an understanding of what the chemical tag does, despite many years of research.

Gene Expression 52

Gene Expression Gene DNA RNA 52

pharmaphorum

NOVEMBER 16, 2021

It is recommended only if it is used as an add-on treatment, after at least one other add-on treatment has not controlled seizures, and treatment is started in a tertiary epilepsy service. Focal onset seizure is a type of epilepsy in which seizures start in one side of the brain, acconting for around 60% of all epilepsy cases.

Drugs 98

Drugs Medicine Clinical Trials Clinical Trials 98

pharmaphorum

DECEMBER 17, 2020

TikTok itself meanwhile says it has taken steps to make sure its users have access to reliable information about the pandemic, which will be stepped up as immunisation programmes start in the UK, US and elsewhere.

Scientist 97

Scientist Vaccination Vaccine Medicine 97

XTalks

NOVEMBER 3, 2022

Novo has been struggling to keep up with the intense demand for Wegovy, resulting in supply shortages as it works to scale up production capacity. “We The company is currently conducting a study to demonstrate Mounjaro’s weight loss effects and secured an FDA Fast Track tag in the obesity indication.

Sales 98

Sales FDA Approval Production Insulin 98

Rethinking Clinical Trials

MAY 10, 2023

All of Us started in 2016 by asking communities what is important to them. We are not at the capability yet where we can open this up. Tags #pctGR, @Collaboratory1 The post Grand Rounds May 5, 2023: All of Us Research Program: Improving Health Through Diverse Technology, Huge Cohorts, and Precision Medicine (Joshua C.

Medicine 130

Medicine Research Clinical Trials Clinical Trials 130

pharmaphorum

JUNE 12, 2022

bluebird bio started last week on tenterhooks, as FDA advisors cast their eyes over data for two gene therapy candidates that are key to its future as a commercially viable concern. Beti-cel has already been approved for marketing in Europe as Zynteglo, with a price tag of around $1.8

Gene Therapy 57

Gene Therapy Gene Marketing Trials 57

pharmaphorum

NOVEMBER 19, 2021

It is recommended as a treatment for people aged two months and older with types 1, 2 and 3 SMA, as well as some people with the condition before they start showing symptoms. million price tag make it is the most expensive treatment ever approved for NHS funding.

Drugs 98

Drugs Gene Therapy Genetic Disease Gene 98

Pharmaceutical Technology

MAY 15, 2023

Innovation S-curve for the pharmaceutical industry Peptide nano-particle conjugates is a key innovation area in the pharmaceutical industry By tagging peptides with nanoparticles, peptide nano-particle conjugates allow enhanced control over their biological behaviour, overcoming intrinsic limitations of the individual materials.

Antibody 130

Antibody DNA Development Vaccination 130

Rethinking Clinical Trials

JUNE 7, 2023

Follow up was conducted with a standardized script to ascertain events, and medical records were collected for event adjudication. Tracy Wang: It is safe to say that none of us predicted COVID, and it hit pretty soon after we started enrollment. The price for Apixaban was $600 per bottle/$6M, and the price for warfarin was $50K.

Clinical Trials 130

Clinical Trials Clinical Trials Trials Cardiology 130

Drug Discovery World

OCTOBER 31, 2023

Following successful engraftment of modified HSCs in the bone marrow, these cells start to produce daughter blood cells which contain the IDS gene and enzyme which are distributed throughout the body, including the brain. The modified HSCs are then infused back into the patient to engraft in the bone marrow.

Gene Therapy 52

Gene Therapy Gene Trials Clinical Trials 52

XTalks

OCTOBER 28, 2021

Second, the mix requires only oil and water, saving consumers from purchasing up to three eggs per mix. While demand for vegan baking ingredients is on the rise, especially among Gen Z and millennial consumers, they remain specialty items and command larger price tags — the Climate Hero Super Cake is no exception.

Protein 98

Protein Packaging Packaging DNA 98

XTalks

JULY 16, 2021

But yet, the price tag is still higher than real meat. A pound of Beyond Meat’s Beef burgers carries a price tag of $6.25, Vox reported. Scaling Up. As companies scale up, prices will naturally decline for them, and in turn, the consumer. The animal agriculture industry has had a multi-decade head start on this.

Protein 105

Protein Production Manufacturing Branding 105

pharmaphorum

JANUARY 11, 2022

Breakthrough designations can speed up the development of new therapies, making them available to patients sooner. It is well-established for conventional drugs and medical devices but has only recently started to be used for DTx. The post Blue Note leukaemia DTx gets FDA breakthrough tag appeared first on.

Development 62

Development Production Drugs 62

pharmaphorum

OCTOBER 29, 2021

Gilead is sponsoring the new study to see if adding Trodelvy can be an alternative chemo when added to Keytruda in the first-line treatment of advanced TNBC, in the hope of moving the ADC up the treatment pathway. billion in sales during the three-month period – way ahead of projections – with turnover expected to reach up to $4.8

Trials 52

Trials Sales FDA Approval Production 52

pharmaphorum

DECEMBER 23, 2021

Daiichi Sankyo’s trial was carried out in 57 patients, with one patient experiencing a complete response after treatment with the ADC, 13 having a partial response, and another 25 showing disease stabilisation after a median follow-up period of five months.

Drugs 70

Drugs Antibody Clinical Trials Clinical Trials 70

Rethinking Clinical Trials

DECEMBER 6, 2022

For the step-down RCT, patient recruitment started in August 2019 with 587 patients consenting and 552 included in the primary analysis. It was a labor of love; the site payment was low; we asked friends to be sites in the trial. Sites have a lot of trials that are competing. One pays more than another. pctGR, @Collaboratory1.

Trials 130

Trials Clinical Trials Clinical Trials Compliance 130

Rethinking Clinical Trials

APRIL 27, 2023

Did some of these questions of autonomy vs. risk come up? In terms of the dialysis component, in routine care we get consent when we start treatment but there are many things in the background. There is a natural assertion of autonomy. I think it is very complex, and it is not black and white.

Trials 130

Trials Clinical Trials Clinical Trials Medicine 130

pharmaphorum

JANUARY 18, 2022

The hope is that they will harness and re-programme natural cellular mechanisms to selectively remove the disease driving proteins from human tissues, working by boosting interactions – gluing – between therapeutically relevant proteins and the machinery used by cells to naturally tag and destroy proteins.

Dermatology 52

Dermatology Protein Pharma Companies Research 52

Rethinking Clinical Trials

JULY 19, 2023

of the patients ended up being prescribed all 3 therapies, and 37.9% Ideally all participants would be identified and enrolled prior to starting the trial. Tags #pctGR, @Collaboratory1 The post Grand Rounds July 14, 2023: Lessons From the COORDINATE-Diabetes Trial (Christopher B. In the usual care arm sites, 14.5%

Trials 130

Trials Cardiology Medicine Nurses 130

Rethinking Clinical Trials

AUGUST 28, 2023

There are also concerns that the ICH document fails to include scientific issues encountered quite often, such as allocation concealment, randomization, loss-to-follow-up, blinded evaluation of endpoints and others. Discussion Themes – How much work was needed to get to this stage where the revisions are up for public comment?

Clinical Trials 130

Clinical Trials Clinical Trials Trials Development 130

Rethinking Clinical Trials

AUGUST 28, 2023

There are also concerns that the ICH document fails to include scientific issues encountered quite often, such as allocation concealment, randomization, loss-to-follow-up, blinded evaluation of endpoints and others. Discussion Themes – How much work was needed to get to this stage where the revisions are up for public comment?

Clinical Trials 130

Clinical Trials Clinical Trials Trials Development 130

pharmaphorum

SEPTEMBER 15, 2020

Companies like prescription glasses firm Warby Parker, shoe brand Rothy’s and tele-dentistry’s SmileDirectClub have grown up in today’s digitally native environment and can offer some key pointers for pharma. Jeremy Richter, Tag. Build on the rapid responses to COVID-19.

Branding 129

Branding Marketing Pharma Companies Life Science 129

pharmaphorum

MARCH 23, 2022

Vyvgart (efgartigimod alfa) became the first drug in the FcRn class to be approved by the FDA last December, and despite a $225,000 annual price tag is predicted to make relatively modest sales in its IV version, which will compete with other IV gMG drugs like AstraZeneca/Alexion’s C5 inhibitor Soliris (eculizumab).

Antibody 52

Antibody Sales FDA Approval Trials 52

pharmaphorum

NOVEMBER 27, 2022

Modular set ups, remote monitoring systems, and automated batch processing can all assist in helping labs respond to issues as quickly and efficiently as possible. For some products, this results in supply chains that are so complex that they start in Asia and circumnavigate the globe twice, before reaching the final destination.

Production 104

Production Manufacturing Drugs Marketing 104

pharmaphorum

JANUARY 5, 2021

Ramping up the immune response to cancer with a second checkpoint inhibitor for use alongside the PD-1/PD-L1 inhibitors is on the wish list of many oncologists, although there have already been some big setbacks, such as the demise of Incyte’s IDO1 inhibitor epacadostat in 2018.

Immune Response 52

Immune Response FDA Approval Drugs Sales 52

Drug Discovery World

JUNE 14, 2023

We have now our lead product in a Phase I/II study, which is a HER-2 directed tag T cell product for patients with HER-2 positive solid tumours. This is not how I started out. I started as a cancer biologist and worked with small molecules and antibodies. I’ve been with a company for more than five years now.

Research 52

Research Engineer In-Vivo Production 52

pharmaphorum

DECEMBER 17, 2021

Aduhelm (aducanumab) was approved by the FDA in June, but has been held back by a glacial rollout as clinicians have questioned the data on which the decision to clear the drug was based, plus a $56,000 per year price tag, which has in turn led to pushback by payers.

Trials 52

Trials Sales Marketing FDA Approval 52

Delveinsight

FEBRUARY 23, 2021

The company plans to use the capital to expand its pipeline of protein-based vaccines and biologic cancer therapies utilizing its innovative and proprietary Trimer-Tag technology platform. The company, however, is optimistic and gearing up to find more opportunities to advance in the ALS market. LightDeck Diagnostics Gets USD 5.65

In-Vitro 52

In-Vitro Vaccination Vaccine Licensing 52

XTalks

FEBRUARY 11, 2022

On February 3, NBCUniversal announced that it was officially sold out of commercial time, with 30-second ad slots commanding a price tag of as much as $7 million in some cases. . The duo starts to reminisce about all the good times they’ve shared, including their “road trip in ‘97.” Lay’s’ “Golden Memories”.

Containment 97

Containment Production Branding Marketing 97

XTalks

FEBRUARY 27, 2024

Despite accounting for only about one percent of all skin cancers, melanomas make up a significant proportion of cancer-related deaths. Addressing the high price tag, Iovance’s commercial chief Jim Ziegler said, “Payers have expressed their appreciation for the value proposition for Amtagvi.” months of follow-up, 43.5

FDA Approval 52

FDA Approval Manufacturing In-Vivo Trials 52

pharmaphorum

DECEMBER 2, 2020

Both in their mid-twenties, the two men set up what was initially a fine chemicals business in a Brooklyn factory, using a loan from Pfizer’s father as capital. By 1868, Pfizer’s revenues had doubled since the start of the war, and their product lines had expanded greatly. Antibiotics marked the transition to the modern Pfizer.

Sales 127

Sales Production Drugs Marketing 127