The Pharma Data

FEBRUARY 22, 2022

As part of its on-going work to track variants, WHO’s Technical Advisory Group on SARS-CoV-2 Virus Evolution ( TAG-VE ) met yesterday to discuss the latest evidence on the Omicron variant of concern, including its sublineages BA.1 Reinfection with BA.2 2 following infection with BA.1 WHO will continue to closely monitor the BA.2

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The Pharma Data

DECEMBER 3, 2020

Utilizing Clover’s proprietary Trimer-Tag © technology, S-Trimer is a trimeric SARS-CoV-2 spike (S)-protein subunit vaccine candidate. Similar to other enveloped RNA viruses such as HIV, RSV and Influenza, SARS-CoV-2 is also an RNA virus that has a trimeric spike (S) protein on its viral envelope. About Trimer-Tag © Technology.

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Vaccination Vaccine Immune Response Protein 52

The Pharma Data

JANUARY 31, 2021

Utilizing Clover’s proprietary Trimer-Tag© technology, S-Trimer is a trimeric SARS-CoV-2 spike (S)-protein subunit vaccine candidate. Similar to other enveloped RNA viruses such as HIV, RSV and Influenza, SARS-CoV-2 is also an RNA virus that has a trimeric spike (S) protein on its viral envelope. About Trimer-Tag© Technology.

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Vaccination Vaccine Trials Protein 52

Rethinking Clinical Trials

OCTOBER 26, 2023

Tags #pctGR, @Collaboratory1 The post Grand Rounds October 20, 2023: A National Initiative to Eliminate Hepatitis C in the United States – Why This Matters to Clinical Trialists (Rachael L. A manuscript is under development. Discussions are currently underway with 13 partner sites.

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Clinical Research Clinical Trials Clinical Trials Research 141

pharmaphorum

FEBRUARY 22, 2021

News of the pause came as UK cost-effectiveness watchdog NICE rejected Zynteglo for regular NHS use in first draft guidance, despite a confidential discount to its price tag of around €1.57 The case comes just weeks after UniQure halted a trial of its haemophilia B gene therapy AMT-061 after an unexpected case of liver cancer.

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Gene Therapy Gene Gene Sequencing Gene Expression 52

Pharmaceutical Technology

MAY 15, 2023

Innovation S-curve for the pharmaceutical industry Peptide nano-particle conjugates is a key innovation area in the pharmaceutical industry By tagging peptides with nanoparticles, peptide nano-particle conjugates allow enhanced control over their biological behaviour, overcoming intrinsic limitations of the individual materials.

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XTalks

JUNE 28, 2023

million price tag of Elevidys, a one-time gene therapy. The progression of DMD is often rapid, and those affected usually face a significantly shortened lifespan with severe physical limitations. Options for managing the symptoms of DMD have been limited. In a media call, Sarepta CEO Douglas Ingram revealed the $3.2

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pharmaphorum

SEPTEMBER 15, 2020

“Digitally native brands are typically agile businesses from the ground up, and agility and flexibility are part of their core makeup,” says Joe Holmes, vice president, marketing services, US at Tag. Jeremy Richter, Tag. Joe began his life at Tag in the UK, bringing efficiencies to his clients, working across all conceivable channels.

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Branding Marketing Pharma Companies Life Science 106

XTalks

JUNE 8, 2021

With a price tag of over $2.5 One of the main reasons why Zolgensma has such a hefty price tag is because it has a small market size in the drug manufacturing industry and hence limited potential to save lives on a large scale. million, Zolgensma is currently the world’s most expensive drug. Why is Zolgensma So Expensive?

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The Pharma Data

OCTOBER 21, 2020

When it came to market in 2014, the price tag for one treatment cycle was $89,000. It’s too soon to say this is a cure.” ” What does seem clear is that the regimen is less toxic than aggressive chemo. Six patients developed an infection with cytomegalovirus (a herpes virus), and four had a drop in white blood cells.

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Drugs Genetics Trials Research 52

The Pharma Data

OCTOBER 21, 2020

When it came to market in 2014, the price tag for one treatment cycle was $89,000. It’s too soon to say this is a cure.” ” What does seem clear is that the regimen is less toxic than aggressive chemo. Six patients developed an infection with cytomegalovirus (a herpes virus), and four had a drop in white blood cells.

Drugs 52

Drugs Genetics Trials Research 52

Pharmaceutical Technology

JUNE 21, 2023

The high price tag may be hard to defend , but with lifetime treatment costs for haemophilia B reaching as high as $23m for some, the single-dose treatment could prove far more cost-effective. Despite the limited market, the price tags of haemophilia make it potentially lucrative. Haemophilia B is a rare condition.

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Gene Therapy Gene Protein Sales 246

Delveinsight

FEBRUARY 25, 2021

The company’s in vivo therapies reach the eye and central nervous system via adeno-associated viruses, while its liver therapies employ lipid nanoparticles (LNPs). DNA hypomethylating agents are epigenetic drugs that eliminate specific chemical tags on DNA, hence turning specific genes on and off and changing the cells’ function.

DNA 52

DNA In-Vivo Genetics Medicine 52

Druggist

OCTOBER 25, 2020

Despite its higher price tag as compared with other products sold for the management of chickenpox PoxClin Cool Mousse is regarded as ‘highly-rated’ and well-priced product on Amazon.co.uk Calamine lotion is cheap and widely available. In this post, I will review the use of calamine lotion for chickenpox. Buy on Amazon Price incl.

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Production Pharmacy Licensing Licensing 52

pharmaphorum

AUGUST 28, 2020

We are ingesting hundreds of thousands of pieces of information daily and we tag that information across locations, disease types, species, and case counts. Established with funding from the National Library of Medicine (NLM), it pulls data from sources including news stories, blogs, social media, and chat rooms. “We

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Medicine Research 63

XTalks

APRIL 6, 2021

Where flour, pasta and other shelf-stable goods once sat in abundance quickly emptied to nothing but price tags. Most grocery shoppers won’t soon forget the perplexing moment last spring when shelves were suddenly bare. The same went for meat and dairy. It was a shocking, yet humbling, sight for most. Lessons Learned.

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Production Sales Vaccination Vaccine 104

The Pharma Data

APRIL 22, 2023

In this study, the researchers focused instead on antibodies that can tag the virus to be eliminated by the immune systems patrolling immune cells, a process called opsonization (see fact box). “There is often talk about wanting to neutralize viruses by preventing them from binding to the body’s cells. Source link: [link]

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XTalks

NOVEMBER 27, 2021

The technical advisory group on SARS-CoV-2 virus evolution (TAG-VE) met on Friday to discuss B.1.1.529, It is normal for viruses to acquire mutations as part of viral evolution; however, uncurbed, increased transmission raise potential for more numbers of, and more frequent, mutations.

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Vaccination Vaccine Protein Scientist 97

Drug Discovery World

OCTOBER 28, 2022

Click’ chemistry used to tag proteins made by cancer cells . News round-up for 24-28 October by DDW Digital Content Editor Diana Spencer . This week’s top stories: . Millions invited to join UK’s largest health research programme . Experimental monoclonal antibodies block EBV infection .

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Drugs Antibody Protein RNA 52

pharmaphorum

AUGUST 26, 2022

BioMarin will no doubt have an eye on the earlier experience of bluebird bio, which secured EU approval for rare disease gene therapy Zynteglo (betibeglogene autotemcel) in 2019 for beta thalassaemia with a price tag of around €1.6 million spread over five years.

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Gene Therapy Gene Antibody Marketing 109

XTalks

NOVEMBER 24, 2022

While the price tag of Hemgenix is quite steep, CSL Behring told Fierce Pharma that the cost of treating patients with moderate to severe hemophilia to healthcare systems is more than $20 million over their lifetimes.

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Gene Therapy Gene FDA Approval Genetics 52

The Pharma Data

MARCH 20, 2021

L volumes, even for notoriously difficult liquid classes like the 100% acetonitrile used to store the Tandem Mass Tags (TMT). The diagnostic test is run under. an ISO17025 quality management system, which. requires new instruments be validated according to. a predefined plan with strict acceptance criteria. If you want to do a lot.

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Reagent RNA Bioinformatics Medicine 52

Delveinsight

DECEMBER 3, 2020

It has been speculated that modifications to the epigenome drive cell ageing, especially a process known as DNA methylation, by which methyl groups are tagged onto DNA. Shinya Yamanaka discovered that the factors could alter the epigenome, and in that way modify mature cells back to a stem cell-like state.

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Gene Therapy Gene Antibody Research 52

XTalks

FEBRUARY 11, 2021

The work garnered Hershey the Nobel Prize in Physiology or Medicine in 1969 , shared with Max Delbrück and Salvador Luria, for their “discoveries concerning the genetic structure of viruses.” Franklin died from ovarian cancer in 1958, likely from exposure to coal during her research. Chase’s exclusion from the prize remains a mystery.

Genetics 119

Genetics DNA Genome Genomics 119

Drug Discovery World

NOVEMBER 9, 2023

Esperanza Rivera de Torre, PhD, Assistant Professor, Center for Antibody Technologies, Department of Bioengineering, Technical University of Denmark, on: ‘Venom on demand: optimising snake toxin yield, folding, and purity in E coli and P pastoris with biotinylation, solubility, and purification tags’.

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The Pharma Data

MAY 15, 2021

Web Beacons are tags that can monitor the behavior of a user visiting the Website or sending an e-mail. COMPANY DOES NOT WARRANT THAT THIS WEBSITE WILL OPERATE ERROR-FREE OR THAT THIS WEBSITE AND ITS SERVER ARE FREE OF COMPUTER VIRUSES OR OTHER HARMFUL MECHANISMS.

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Production Containment Medicine Vaccination 52

The Pharma Data

MAY 4, 2021

1.351 lineage) spike mutations and showed that while the results indicated a reduction in neutralization of virus with all the South African variant spike glycoprotein mutations, all the sera neutralized all the viruses tested. The study investigated the full set of South African variant (also known as B.1.351 Amy Rose 212.733.7410.

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