Remove tag world-cancer-day
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Epigenetics discovery could lead to new class of cancer drugs

Drug Discovery World

A new paper has solved the 20-year mystery of how epigenetic modifications act as traffic lights to control gene expression and could ultimately speed up the development of a new class of epigenetic cancer drugs. Epigenetics is still largely unexplored and referred to as the ‘dark matter’ of the genome.

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Drug Combo May Be Safe, Effective Therapy for Rare Leukemia

The Pharma Data

21, 2020 — A combination of two “targeted” therapies can beat back a rare form of blood cancer — without the toxic effects of chemotherapy, a new study has found. 22 in the New England Journal of Medicine , could lead to an effective — and chemo-free — treatment for the cancer. WEDNESDAY, Oct.

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Sprycel Plus Blincyto Drug Combo May Be Safe, Effective Therapy for Rare Leukemia

The Pharma Data

21, 2020 — A combination of two “targeted” therapies can beat back a rare form of blood cancer — without the toxic effects of chemotherapy, a new study has found. 22 in the New England Journal of Medicine , could lead to an effective — and chemo-free — treatment for the cancer. WEDNESDAY, Oct.

Drugs 52
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Q&A: A decade on, what’s next for CAR-T therapies?

Pharmaceutical Technology

But access to these treatments continues to remain limited due to high price tags and variable availability across regions. With blood cancers, you inject the product, and the cells are there, and the target is there. Across the world, to varying degrees, the regulations were written in an era of small molecules and biologics.

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New to ELRIG Drug Discovery 2022: Tech Theatre supported by DDW

Drug Discovery World

The first day of the Tech Theatre will feature the talk Taking your first steps towards liquid handling automation , presented by Anne Hammerstein, Ph.D, Also on that day the Tech Theatre will run a presentation on How automation can push the discovery of biologics and biosimilars? Product Manager, SPT Labtech. Martin-Immanuel.

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Merck Announces Withdrawal and Refiling under the Hart-Scott-Rodino Act and Extension of Tender Offer to.

The Pharma Data

Merck has tagged to withdraw its Premerger Notification and Report Form, which was originally filed on October 14, 2021, to give the Federal Trade Commission (the “ FTC”) with fresh time for review, and expects to refile similar form on or about November 1, 2021. The Depositary for the tender offer is Computershare Trust Company,N.A.,

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First patient dosed with PI3K? inhibitor for solid tumours

Drug Discovery World

Totus Medicines has dosed its first patient in a Phase I clinical trial of TOS-358, a first-in-class covalent PI3Kα inhibitor for the treatment of numerous cancers with known PIK3CA mutations. The post First patient dosed with PI3Kα inhibitor for solid tumours appeared first on Drug Discovery World (DDW).