Drug Discovery World

APRIL 3, 2023

I quickly recognised the commercial value of aptamers as being able to address the gap in the market where antibodies fail to perform, and together we established the business to begin aptamer development. What advantages do they offer over antibodies?   DS: How are aptamers currently used in the development of precision treatments?

Antibody 52

Antibody Gene Therapy Gene In-Vitro 52

Drug Discovery World

APRIL 10, 2024

Biophysical data combined with functional assays are needed to predict efficacy and potency, optimise drug delivery, assess critical quality attributes, and improve biologics drug design. The post How to accelerate the development of advanced biotherapeutics appeared first on Drug Discovery World (DDW).

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Development Bioassay Antibody Drug Delivery 40

Roots Analysis

MARCH 21, 2022

However, several drug delivery devices that enable patients to self-administer their respective medications are now available. Subcutaneous drug delivery systems – the helping hand for patients. The emergence of safer and patient-friendly devices is acting as a strong enabler for subcutaneous delivery of therapeutics.

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Drug Delivery Systems Drug Delivery Antibody Marketing 52

Delveinsight

MARCH 2, 2021

HitGen & UPPTHERA Collaborate for Drug Delivery Research. HitGen has entered into a collaboration for drug discovery research with UPPTHERA to identify small molecule Hits against previous known-to-be undruggable targets and novel E3 ligase.

Drug Delivery 40

Drug Delivery Research Drugs Gene Editing 40

pharmaphorum

SEPTEMBER 22, 2021

Texas-based Abexxa has been on the Boehringer’s radar since it was set up, as it provided seed funding for the preclinical-stage company in 2016, buying into its approach of developing antibodies against targets inside cancer cells, rather than on the cell membrane. Last December, Boehringer paid €1.8

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Antibody Drug Delivery Vaccination Vaccine 92

Drug Discovery World

JUNE 22, 2023

This has been demonstrated to be an effective way to improve AAV delivery, to increase the breadth of expression in pre-clinical models, and to shield AAVs from neutralising antibodies. “We The post Evox Therapeutics acquires exosome AAV technology from Codiak appeared first on Drug Discovery World (DDW).

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Gene Therapy Gene Editing Drug Delivery Gene 52

XTalks

NOVEMBER 3, 2021

The team also learned about the FDA approval of Genentech’s new ocular implant drug delivery system, called Susvimo, for the treatment of neovascular, or wet, age-related macular degeneration (nAMD). Genentech’s New Ocular Implant Drug Delivery System for Macular Degeneration Could Be a Game Changer.

Life Science 52

Life Science Drug Delivery Systems Vaccination Vaccine 52

pharmaphorum

APRIL 29, 2021

To achieve this, the agenda will allow delegates to: Explore the translation of BBB-penetrating antibodies to non-human primates , and new possibilities for in vivo brain imaging of antibody neuropharamacokinetics. 3-day Conference | June 28-30, 2021.

Drug Delivery 52

Drug Delivery Gene Therapy In-Vivo Antibody 52

Roots Analysis

AUGUST 8, 2023

Furthermore, a wide variety of drugs and macromolecules, including DNA , proteins, and imaging agents, can be encapsulated in liposomal vesicles due to their unique ability to entrap both lipophilic and hydrophilic substances. The various therapeutic applications of liposomes in drug delivery have been highlighted in the figure.

Drug Delivery Systems 52

Drug Delivery Systems Drug Delivery Drugs In-Vivo 52

pharmaphorum

MARCH 15, 2022

Sarclisa is a CD38-directed antibody that is currently approved as an intravenous therapy for relapsed multiple myeloma in combination with either Bristol-Myers Squibb’s Pomalyst (pomalidomide) plus dexamethasone or Amgen’s Kyprolis (carfilzomib) plus dexamethasone. .

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Trials Sales Drug Delivery Antibody 97

Roots Analysis

OCTOBER 13, 2023

Over the last two decades the pharmaceutical industry has observed a paradigm shift from conventional drug delivery strategies to more enhanced, potent, and targeted therapeutics. This led the researchers to find alternative pathways and drug delivery strategies to enhance the potent delivery of the drug to the site of action.

Drugs 40

Drugs Antibody RNA Genetics 40

Outsourcing Pharma

SEPTEMBER 9, 2021

Nucala, a monoclonal antibody indicated for patients with chronic rhinosinusitis with nasal polyps, has been approved by the Food and Drug Administration.

Drugs 81

Drugs Antibody Drug Delivery 81

Roots Analysis

MARCH 16, 2022

In order to promote the use of exosomes in various therapeutic applications including targeted drug delivery vehicles, engineered exosomes and many more, there are a number of companies that offer services related to the isolation, purification, characterization or quantification of exosomes. Our Social Media Platform. Web: [link].

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Marketing Manufacturing Drug Delivery Drug Delivery Systems 59

Roots Analysis

FEBRUARY 26, 2024

Roots Analysis – Leaders in Pharmaceutical & Biotechnology Market Research You may also be interested in the following titles: Continuous Manufacturing (Small Molecules and Biologics) Market Subcutaneous Biologics, Technologies and Drug Delivery Systems Market Antibody Discovery Services and Platforms Market Our Social Media Platform Web: (..)

Drug Delivery Systems 52

Drug Delivery Systems Marketing Drug Delivery Development 52

pharmaphorum

JUNE 22, 2021

GlaxoSmithKline (GSK) has reported encouraging data for its COVID-19 antibody sotrovimab, and an alliance with Halozyme to develop a new generation of long-acting HIV drugs, as it prepares to give a much-anticipated update to shareholders tomorrow. So far, all the other antibodies are also delivered by intravenous infusion.

Antibody 52

Antibody Protein Drug Delivery FDA Approval 52

Roots Analysis

FEBRUARY 16, 2023

As projected by Roots Analysis, antibodies will have the highest share in this market. Further, majority of capacity is available with service providers headquartered in Asia-Pacific. This trend is likely to continue in the future.

Drug Delivery 52

Drug Delivery Production Marketing Antibody 52

Roots Analysis

MARCH 13, 2022

In the last decade alone, the annual number of approvals of biopharmaceuticals (including monoclonal antibodies, recombinant proteins, vaccines and gene therapies), by the US FDA, have steadily risen. Over the years, the rising popularity of biologics has led to a paradigm shift in the healthcare industry. Our Social Media Platform.

Manufacturing 52

Manufacturing Drug Delivery Marketing Drug Delivery Systems 52

pharmaphorum

DECEMBER 18, 2020

With the aim of achieving a higher quality of life for those with unfavourable prognoses, this project, funded by Innovate UK, the UK’s innovation agency, brings together partners with a wealth of experience and specialist know-how in the areas of nanoparticle development, drug delivery and bioimaging.

Drug Delivery 52

Drug Delivery Medicine Clinical Trials Clinical Trials 52

The Pharma Data

MARCH 15, 2022

For the Sarclisa ® subcutaneous formulation delivery, Sanofi has partnered with drug delivery technology innovator company Enable Injections , Inc. to advance the development of a subcutaneous delivery for Sarclisa ® with the goal of offering a unique patient-centric treatment experience. John Reed , MD , Ph.

Life Science 52

Life Science Antibody Clinical Trials Clinical Trials 52

pharmaphorum

DECEMBER 23, 2020

Roche has secured EU approval for Phesgo, a fixed-dose combination of its breast cancer drugs Herceptin and Perjeta that is easier and cheaper to administer to patients – and also provides a defence against biosimilar competition. The post Roche claims EU okay for Herceptin/Perjeta combination Phesgo appeared first on.

Sales 52

Sales Drug Delivery Antibody Production 52

XTalks

OCTOBER 27, 2021

Genentech’s ocular implant drug delivery system for treatment of macular degeneration has received approval from the US Food and Drug Administration (FDA). Susvimo delivers ranibizumab via a port delivery system into a surgically placed implant in the eye, allowing for continuous delivery of the drug.

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Drug Delivery Systems Drug Delivery FDA Approval Drugs 104

The Pharma Data

OCTOBER 20, 2020

” Mr. Bliss joins TLC following interim roles in cellular therapy, drug delivery and combination therapy where he led efforts to confirm research outcomes and partner the various technologies. Earlier in his career, he ran business-development functions at Amgen and Baxter.

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Licensing Licensing Drug Delivery Business Development 40

Roots Analysis

FEBRUARY 14, 2023

This can be attributed to the fact that liposomes can actively target tumor tissues when used in combination with antibodies. Majority of the articles (51%) are focused on evaluating liposomes for use in cancer therapy. These platforms have created an opportunity for the product developers to share their innovative ideas in this domain.

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Development Manufacturing Drug Delivery Systems Contract Manufacturing 52

pharmaphorum

DECEMBER 15, 2022

Oxsonics Therapeutics, which offers an ultrasound-based drug delivery platform, appointed Jérôme Marzinski, a board member at Cimon Medical and former CEO of ophthalmic diagnostic company Visiometrics into its top job. More CEO shakeups. Bungay formerly served as CEO of Chroma Therapeutics and COO of Mereo Biopharma.

Sales 52

Sales In-Vitro Antibody Drug Delivery 52

The Pharma Data

JANUARY 16, 2021

It has become the de facto standard equipment for high titer transient protein expression platforms used by many leading Chinese antibody drug pharmaceutical companies and IVD (In Vitro Diagnostics) companies since its launch in Oct.

Protein 52

Protein Production Antibody In-Vitro 52

Delveinsight

JANUARY 22, 2021

Thrombocytopenia pipeline possesses potential drugs in mid-stage developments to be approved shortly. Efgartigimod (ARGX-113) is an investigational therapy for IgG-mediated autoimmune diseases, designed to leverage the natural interaction between IgG antibodies and the recycling receptor FcRn.

Marketing 65

Marketing Drugs Antibody Compliance 65

The Pharma Data

APRIL 8, 2021

Advances in Drug Delivery (Session #ADT08), with a discussion on the advances and innovations fueling the development of the next generation of antibody drug conjugates. The introduction of AZD8853, a novel antibody targeting GDF15 for tumours refractory to immunotherapy treatment.

DNA 52

DNA Medicine Genome Genomics 52

The Pharma Data

JANUARY 17, 2021

Evox uses its proprietary DeliverEX technology to modify exosomes using various molecular engineering, drug loading, and targeting strategies to facilitate targeted drug delivery to organs of interest, including the brain and the central nervous system.

Life Science 40

Life Science Drug Delivery Engineer Drugs 40

pharmaphorum

OCTOBER 11, 2022

The results were disappointing, with only a minority of patients getting the intranasal regimen showing signs of SARS-CoV-2 antigen-specific antibody responses in the mucosa, which according to the researchers “rarely” exceeded the levels one would see after a COVID-19 infection.

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Vaccination Vaccine Immune Response Development 116

Roots Analysis

MARCH 9, 2022

In the last decade alone, the annual number of approvals of biopharmaceuticals (including monoclonal antibodies, recombinant proteins, vaccines, and gene therapies), by the US FDA, have steadily risen. Over the years, the rising popularity of biologics has led to a paradigm shift in the healthcare industry.

Manufacturing 52

Manufacturing Marketing Contract Manufacturing Protein 52

Roots Analysis

MARCH 3, 2022

Since the approval of Soliris® in 2007, an anti-C5 antibody, the field of complement drug discovery has gained significant attention. Currently, nine complement therapeutics are commercially available, while around 190 molecules are under development for various disease indications. Our Social Media Platform. Web: [link].

Drug Delivery Systems 52

Drug Delivery Systems Marketing Immune Response Dermatology 52

The Pharma Data

JANUARY 17, 2021

Darzalex Faspro is the only CD38-directed antibody that has been approved for subcutaneous injection for multiple myeloma, and now AL amyloidosis. It is co-formulated with recombinant hyaluronidase PH20 (rHuPH20), Halozyme’s ENHANZE drug delivery technology.

FDA Approval 52

FDA Approval Drug Delivery Doctors Doctor 52

pharmaphorum

JUNE 30, 2021

AdCOVID was able to stimulate antibodies that bound the SARS-CoV-2 spike protein and were able to neutralise the virus, but not in sufficient quantities and in too few patients.

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Vaccination Vaccine Trials Immune Response 98

The Pharma Data

MAY 15, 2023

If approved, this would be the third indication for Vabysmo, the first bispecific antibody available for the treatment of retinal conditions that can cause blindness.” 7 About Vabysmo® (faricimab) Vabysmo is the first bispecific antibody approved for the eye. Roche’s Chief Medical Officer and Head of Global Product Development. “If

Antibody 40

Antibody In-Vitro Clinical Development Medicine 40

XTalks

AUGUST 30, 2022

One of the biggest challenges with developing therapies to treat CNS disorders is the delivery of systemically administered investigational products (IPs) to the brain, which is limited by the blood-brain barrier. Some methods of direct CNS administration include intrathecal, intraparenchymal and intracerebroventricular (ICV) delivery.

Trials 83

Trials Drug Delivery Drugs Gene 83

The Pharma Data

JANUARY 24, 2021

Faricimab is the first bispecific antibody designed for the eye. Faricimab is the first investigational bispecific antibody designed for the eye. This high treatment burden can lead to under-treatment and potentially less than optimal vision outcomes. chief medical officer and head of Global Product Development. About faricimab.

Antibody 40

Antibody Medicine Drug Delivery Development 40

The Pharma Data

APRIL 12, 2023

4-7 Additionally, phase I data for an investigational anti-interleukin-6 (IL-6) treatment in uveitic macular edema (UME), to be presented for the first time, suggest the monoclonal antibody may improve visual acuity in patients with UME. 1 4 About Vabysmo ® ( faricimab ) Vabysmo is the first bispecific antibody approved for the eye.

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