Scienmag

NOVEMBER 24, 2020

Credit: RIKEN A research team at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has succeeded in experimentally evolving the common bacteria Escherichia coli under pressure from a large number of individual antibiotics. Their findings, published in the scientific […].

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Scienmag

JANUARY 8, 2021

Now research reveals that bacteria too have internal clocks that align with the 24-hour cycle of life on Earth. The research answers a long-standing biological question and could have implications for the timing of drug delivery, biotechnology, and […].

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Scienmag

MAY 26, 2021

Researchers turn now to see how COVID-19 pandemic affected microbiome in each city Each city has its own unique microbiome, a “fingerprint” of viruses and bacteria that uniquely identify it, according to a new study from an international consortium of researchers that included a team from the University of Maryland School of Medicine (UMSOM). (..)

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Scienmag

DECEMBER 18, 2020

Researchers take a closer look at the genomes of microbial communities in the human mouth Credit: Photo credit: Jessica Mark Welch, Marine Biological Laboratory.

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Scienmag

JANUARY 20, 2021

Credit: Jan Zrimec/Chalmers University of Technology Pathogenic bacteria in humans are developing resistance to antibiotics much faster than expected. Now, computational research at Chalmers University of Technology, Sweden, shows that one reason could be significant genetic transfer between bacteria in our ecosystems and to humans.

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Scienmag

MARCH 2, 2021

Kim New research suggests that the ability of green algae to eat bacteria is likely much more widespread than previously thought, a finding that could be crucial to environmental and climate science. Bock & E. The work, […].

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Scienmag

DECEMBER 3, 2020

A new study has found that a novel T cell genetically engineered by University of Arizona Health Sciences researchers is able to target and attack pathogenic T cells that cause Type 1 diabetes, which could lead to new immunotherapy treatments.

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Medical Xpress

JANUARY 4, 2023

Like humans, bacteria and archaea can be attacked by viruses. Bacterial defenses, such as CRISPR-Cas systems, have diverse proteins and functions that help bacteria protect themselves against foreign invaders. These microorganisms have developed their own immune defense strategies against their pathogens.

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STAT News

MARCH 29, 2023

Fortunately, there were already multiple strains of bacteria that infected and killed these insects. Why not learn from the best? Continue to STAT+ to read the full story…

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Pharmaceutical Technology

DECEMBER 14, 2022

Bacteria naturally develop resistance to antibiotics over time, through genetic mutation, horizontal gene transfer between bacteria, or because of selective pressure. Virus versus bacteria. Phages are viruses of bacteria. Secondly, the relationships between phages and bacteria are very specific.

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STAT News

NOVEMBER 14, 2022

This year’s class of 28 Wunderkinds were selected from more than 200 brilliant researchers.

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Scienmag

JULY 16, 2021

Credit: Vaughn Cooper PITTSBURGH, July 16, 2021 – For the first time ever, researchers from the University of Pittsburgh School of Medicine discovered that phages–tiny viruses that attack bacteria–are key to initiating rapid bacterial evolution leading to the emergence of treatment-resistant “superbugs.”

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Scienmag

MARCH 2, 2021

Published today in Nature Communications, the researchers modified E. […]. . — Envisioning an animal-free drug supply, scientists have — for the first time — reprogrammed a common bacterium to make a designer polysaccharide molecule used in pharmaceuticals and nutraceuticals.

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Camargo

JULY 27, 2021

The technology of gene therapy is possible due to extensive DNA research and our resulting understanding of many diseases on the genetic level, and it encompasses several mechanisms such as introducing new genes (gene addition) and inactivating or replacing mutated genes (gene editing). Formulation Considerations.

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Drug Discovery World

JULY 17, 2023

Paul Denslow , CEO, Intus Bio, discusses how a new approach to tracking gut bacteria can revolutionse our understanding of the microbiome and bring about new discoveries for therapeutics. It’s a long-held doctrine that there’s no effective method to track the microbiome during drug research and development.

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Medical Xpress

NOVEMBER 16, 2022

The spread of antibiotic resistant bacteria in hospitals could be greatly reduced thanks to research by The University of Queensland and Queensland Health.

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Scienmag

MAY 10, 2021

Researchers reconstruct the oral microbiomes of Neanderthals, primates, and humans, including the oldest oral microbiome ever sequenced from a 100,000-year-old Neanderthal, and discover unexpected clues about human evolution and health Credit: Werner Siemens Foundation, Felix Wey Living in and on our bodies are trillions of microbial cells belonging (..)

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The Pharma Data

JUNE 14, 2023

But the bacteria can sometimes change their behavior and enter the bloodstream, causing chronic localized infections to become acute and potentially fatal. However, researchers at the Georgia Institute of Technology have identified the major mechanism behind the transition between chronic and acute P. aeruginosa infections.

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STAT News

SEPTEMBER 30, 2022

With so many “unprecedented,” “transformative” breakthroughs happening, forecasting which one will be awarded top research honors isn’t getting any easier. But with the naming of this year’s Nobels fast approaching — the medicine award will be announced on Oct. 3, physics on Oct.

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Medical Xpress

DECEMBER 7, 2022

Researchers aiming to predict which staph-infection patients might develop a related kidney disease have found a high frequency of gene mutations in the infecting bacteria of affected patients, which suggests these variants may play a role in the body's initiation of the renal damage.

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Scienmag

JUNE 24, 2021

NIH scientists discover that bacteria may drive activity of many hallmark aging genes in flies Credit: Courtesy of the Giniger lab NIH/NINDS.

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pharmaphorum

OCTOBER 7, 2020

Originally discovered in bacteria as a defense mechanism against pathogens, CRISP/Cas9 has made it possible to make exquisitely detailed and precise alterations to DNA sequences on demand, and as a tool for molecular biology has already transformed research into diseases and drug discovery. What started as a curiosity?driven,

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Drug Discovery World

NOVEMBER 17, 2022

The rapidly growing area of synthetic biology – including molecular biology, biotechnology, biophysics, and genetic engineering – is having a marked impact on the drug discovery landscape. The Rockefeller University 2 recently reported the development of a synthetic antibiotic that could potentially work against drug-resistant bacteria.

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The Pharma Data

NOVEMBER 12, 2020

12, 2020 — Lung cancer patients who harbor certain bacteria in the airways may have a poorer prognosis, a new study finds, adding to evidence that the body’s “microbiome” may play a role in cancer patients’ outlook. None of that proves the bacteria, themselves, were to blame, Segal said. THURSDAY, Nov.

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Pharmaceutical Technology

FEBRUARY 15, 2023

The key component in all vaccines is one or more active ingredients made from viruses or bacteria, also called antigens, which generates an immune response. The active component of the Pfizer-BioNTech vaccine tozinameran, contains the genetic code for the coronavirus spike protein, inside a lipid (fat) capsule.

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Drug Discovery World

JULY 12, 2022

Destiny Pharma will establish a research project with the Cystic Fibrosis Foundation where it will establish the potential of its XF-73 drug as a treatment for MRSA infected cystic fibrosis patients. . Cystic fibrosis (CF) is a progressive, genetic disease that causes persistent lung infections and limits the ability to breathe.

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Scienmag

AUGUST 17, 2020

Credit: Professor Mark Schembri There is new hope for approximately 700,000 people who die each year from antibiotic resistant infections, with University of Queensland researchers discovering how bacteria share antibiotic-resistance genes. “The diminishing […].

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Scienmag

OCTOBER 1, 2020

Work allows genomic monitoring for epidemic strains of Vibrio cholerae bacteria The evolution of epidemic and endemic strains of the cholera-causing bacterium Vibrio cholerae in Argentina has been mapped in detail by researchers at the Wellcome Sanger Institute, the London School of Hygiene and Tropical Medicine, the University of Cambridge and the (..)

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The Pharma Data

JULY 11, 2021

We are talking about the microbiome – the vast collection of bacteria in the human gut. The microbiome has been the focus of research for 20 years – ever since a new technique made it possible to analyse these bacteria quickly and precisely: high-throughput sequencing. In doing so, they induce epigenetic changes.

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Scienmag

JANUARY 22, 2021

Cryo-electron microscopy study allows researchers to visualize structural changes in an E.

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The Pharma Data

JANUARY 4, 2021

Improper disposal of antibiotics also releases these drugs into the environment, and researchers working with these drugs in the lab also have concern over their ultimate effects on study results. The process described in the research was previously developed by a former graduate student research in O’Malley’s lab, Justin Yoo.

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Scienmag

JANUARY 12, 2021

The John Innes Centre researchers used the technology to create a new strain of Streptomyces formicae bacteria which over-produces the medically promising molecules. Martins Scientists have used gene-editing advances to achieve a tenfold increase in the production of super-bug targeting formicamycin antibiotics.

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pharmaphorum

JANUARY 20, 2021

Ella, 28, was diagnosed with cystic fibrosis – a rare genetic disease which causes a build-up of thick, sticky mucus in the lungs, digestive tract, and sinuses – at 18 months old. This sticky mucus gets trapped and breeds infections from bacteria I inhale,” says Ella, who adds she was “terrified” of doctors as a child.

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Scienmag

FEBRUARY 19, 2021

Researchers at University of Illinois Urbana-Champaign previously demonstrated a technique using transcription factor decoys to activate large, silent BGCs in bacteria to aid in natural product discovery. […]. However, many uncharacterized microbial BGCs remain inaccessible.

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Scienmag

MARCH 9, 2021

Modern hospitals and antibiotic treatment alone did not create all the antibiotic resistant strains of bacteria we see today. Instead, selection pressures from before widespread use of antibiotics influenced some of them to develop, new research has discovered.

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XTalks

JULY 26, 2021

But several researchers and experts have brought to light some food safety concerns of plant-based meat, and why it must be treated differently than that of animal protein. Plant-based meat has been in the spotlight in recent years thanks to its professed health, safety and environmental benefits over its animal-based counterpart.

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Drug Discovery World

DECEMBER 14, 2023

The new hub will become a part of the already thriving life sciences sector in the Glasgow area, most of which is centred around the university, the Cancer Research UK Scotland Institute and the BioCity cluster, making Glasgow and its surrounds one of the most important regions for drug discovery and development in the UK.

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