Scienmag

JULY 16, 2021

Credit: Vaughn Cooper PITTSBURGH, July 16, 2021 – For the first time ever, researchers from the University of Pittsburgh School of Medicine discovered that phages–tiny viruses that attack bacteria–are key to initiating rapid bacterial evolution leading to the emergence of treatment-resistant “superbugs.”

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Research Bacteria Medicine Bioinformatics 73

Drug Discovery World

NOVEMBER 17, 2022

Researchers have identified 35 genes associated with long-term Lyme disease that could potentially be used as biomarkers to diagnose patients with the condition. . The findings, from the Icahn School of Medicine at Mount Sinai in New York and published in the journal Cell Reports Medicine , may also lead to new therapeutic targets.

Genetics 52

Genetics RNA Immune Response Bioinformatics 52

Scienmag

NOVEMBER 12, 2020

In a study that has unprecedented implications to advance both medicine and biodiversity conservation, researchers have sequenced 131 new placental mammal genomes, bringing the worldwide total to more than 250 In a study that has unprecedented implications to advance both medicine and biodiversity conservation, researchers have sequenced 131 new placental (..)

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Biobanking Medicine Genome Genomics 41

Scienmag

FEBRUARY 10, 2021

Data demonstrates new increased diversity in genetic studies and provides new insights into population-specific diseases Researchers at the University of Maryland School of Medicine (UMSOM) and their colleagues published a new analysis today in the journal Nature from genetic sequencing data of more than 53,000 individuals, primarily from minority (..)

Genetics 71

Genetics Research Medicine Bioinformatics 71

Drug Discovery World

OCTOBER 20, 2023

The acquisition of Olink underscores the profound impact that proteomics is having as our customers continue to advance life science research and precision medicine,” said Marc Casper, Chairman, President and Chief Executive Officer of Thermo Fisher.

Drugs 52

Drugs Antibody DNA Gene Therapy 52

pharmaphorum

JULY 5, 2022

Cell therapy specialist Mogrify has struck a deal with Japanese drugmaker Astellas to look at ways to deploy regenerative medicine to treat hearing loss caused by factors such as chronic exposure to loud noises.

In-Vivo 90

In-Vivo Bioinformatics Genetics Licensing 90

Drug Discovery World

APRIL 18, 2023

DDW’s Megan Thomas rounds up highlights from Tuesday 17 April at AACR 2023, from AI and mathematical oncology to winners of the AACR James S Ewing-Thelma B Dunn Award for Outstanding Achievement in Pathology in Cancer Research. Dunn Award for Outstanding Achievement in Pathology in Cancer Research Another award highlight was the AACR James S.

Genetics 52

Genetics DNA Research Bioinformatics 52

Drug Discovery World

NOVEMBER 30, 2023

Kimryn Rathmell has been chosen as the 17 th director of the National Cancer Institute (NCI), bringing her experience as leader of the Department of Medicine at the Vanderbilt University Medical Center and Physician-in-Chief at the Vanderbilt University Adult Hospital and Clinics.

Drugs 52

Drugs Genome Genomics Bioinformatics 52

XTalks

SEPTEMBER 28, 2020

The test is based on the detection of actionable genes – genes with known driver mutations that can be targeted by an approved therapy (or investigational therapies in clinical trials). The panel of genes in the test only include known NSCLC-associated genes, making the test specific to the disease. Personalized Approach.

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Gene DNA Life Science Genotype 105

XTalks

JULY 19, 2021

The technology powering GeneCompass is already in use by some well-known commercial laboratories, research institutions, fertility clinics and hospitals,” said Alexander Bisignano, Phosphorus co-founder and CEO, in a press release. “We The Phosphorus GeneCompass test has a list price of $249.

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Genetics Genome Genomics Gene 98

Scienmag

SEPTEMBER 4, 2020

Jonek The European Research Council (ERC) has awarded ERC Starting Grants to two researchers from Bielefeld University. million euros for top-level research in their disciplines. ERC Starting Grants for Professor Dr Martina Hofmanová and Dr Toni Goßmann Credit: Photo: Bielefeld University /S. They will each receive 1.5

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Research Bioinformatics Gene Genetics 56

Drug Discovery World

APRIL 14, 2023

The American Association for Cancer Research (AACR) will honour the following cancer researchers, physician-scientists, advocates, and journalists during its annual meeting to be held April 14-19 at the Orange County Convention Center in Orlando, Florida. June’s award lecture will be held on Sunday April 16 at 4:30pm ET.

Genetics 52

Genetics Research Medicine Clinical Research 52

Scienmag

DECEMBER 16, 2020

15, 2020 — The Translational Genomics Research Institute (TGen), an affiliate of City of Hope, has identified a specific genetic target that could help explain the tremendous variation in how sick those infected with COVID-19 become. Comparative analysis of human and animal coronaviruses strains implicates miR1307 PHOENIX, Ariz.

Gene 40

Gene Genome Genomics Genetics 40

Drug Discovery World

OCTOBER 26, 2023

To enable Evotec’s precision medicine approach, we have been building technology platforms that allow PanOmics or multi-omics data generation at an industrialised scale. The technologies cover the whole range of biomolecules from genes to protein to metabolites. This article is sponsored by Evotec.

Drugs 52

Drugs Protein Genome Genomics 52

Drug Discovery World

JULY 26, 2023

An industry overview of the role of the microbiome in precision medicine, and its interplay with research tools, diagnostics, and therapeutic development. Research increasingly demonstrates that within each discrete microbial environment (e.g., identifying single nucleotide polymorphisms or chromosomal rearrangements).

Medicine 52

Medicine Genome Genomics Bioinformatics 52

Scienmag

APRIL 8, 2021

Credit: IRB Barcelona In cancer, personalised medicine takes advantage of the unique genetic changes in an individual tumour to find its vulnerabilities and fight it. Researchers at IRB Barcelona led […].

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Scientist DNA Genetics Medicine 53

pharmaphorum

SEPTEMBER 14, 2020

Here he gives us a deeper look at how genomic medicine is evolving and the barriers that are preventing it from reaching its full potential. At that time, we thought this would be the holy grail for medicine. Now, however, the field is changing with respect to genomic medicine.

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Genome Genomics Medicine Gene 106

Scienmag

MARCH 22, 2021

Credit: WEHI, Australia Melbourne researchers have revealed how melanoma cells are flooded with DNA changes as this skin cancer progresses from early, treatable stages through to fatal end-stage disease.

DNA 96

DNA Genome Genomics Research 96

Drug Discovery World

JULY 11, 2023

While the potential for better insights has grown, acquiring powerful tools that can harness that data, and turn it into useful, actionable information, has increasingly become one of the most important aspects of life science research. Advances in quantum computing are also showing early promise for increasingly complex data analyses.

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Big Data Development Life Science Drugs 40

Scienmag

SEPTEMBER 30, 2020

Researchers engineer RNA-targeting compounds that disable the pandemic coronavirus’ replication engine Credit: Scott Wiseman for Scripps Research JUPITER, FL – Sept.

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Engineer RNA Research Drugs 68

Drug Discovery World

JUNE 7, 2023

That’s why at Macomics we have developed the ENIGMAC discovery platform, which allows stringent bioinformatic analysis coupled with macrophage gene editing technology; our platform enables strong target validation and drug screening using biologically relevant functional assays.

In-Vivo 52

In-Vivo Gene Editing Engineer Bioinformatics 52

pharmaphorum

APRIL 15, 2021

We have a pipeline of novel therapeutics and technological approaches, advancing a diverse array of candidates, including small molecules, biologics and cell and gene therapies, so a lot of the time we are working where there’s little, or no precedent.”. In principle, this goes beyond medicines. Looking to the future.

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Development Manufacturing Production Bioinformatics 59

Scienmag

JANUARY 13, 2021

The project was an international effort, bringing together researchers in Ukraine, […].

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Genome Genomics Genetics Research 98

Drug Discovery World

OCTOBER 25, 2023

DDW Editor Reece Armstrong speaks to Dr Darrell Green , Lecturer in RNA Biology Biomedical Research Centre Norwich Medical School University of East Anglia, about his work using next generation sequencing (NGS) and the areas the technology is impacting within drug discovery and development. The second concept is largely in oncology.

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Bioinformatics Genetics RNA Drugs 115

Drug Discovery World

FEBRUARY 6, 2023

Johannes Goll, Global Head of Emmes’ Biomedical Data Science and Bioinformatics department, explains how big data analytics can deliver improved therapies and bring clinical research one step close to realising the potential of personalised care.

Big Data 52

Big Data RNA Bioinformatics Vaccination 52

XTalks

NOVEMBER 7, 2022

Such information can reveal details about tumor staging, tumor progression, heterogeneity, gene mutations and clonal evolution. The researchers concluded that the concentration of mutant fragments is correlated to the stage of the cancer and the type of cancer. These tumor-derived entities are used to derive genomic and proteomic data.

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Clinical Trials Clinical Trials Trials FDA Approval 98

XTalks

DECEMBER 13, 2023

In 2023, biotechnology and pharmaceutical companies leverage cutting-edge technology and significant investments in research and development (R&D) to continue pushing the boundaries of innovation in the healthcare sector, transcending the challenges posed by the pandemic.

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Genetics Vaccination Vaccine DNA 111

Drug Discovery World

APRIL 29, 2024

Bill Dawson, Chair, Medicines Manufacturing Industry Partnership (MMIP): Dawson is Head of Biologics and Devices Manufacturing at GSK and has over 25 years’ experience in the vaccines, biopharma, pharmaceutical and clinical research (CRO) industries. He has a PhD in Bioinformatics from the University of Cambridge.

Drugs 52

Drugs Sales Gene Therapy Life Science 52

Scienmag

MAY 14, 2021

Credit: WEHI, Australia Australian researchers have documented the diversity of cells in the human breast, explaining the relationship between healthy breast cells and breast cancer cells.

Gene Expression 63

Gene Expression Bioinformatics Gene Research 63

Drug Discovery World

NOVEMBER 13, 2023

Thereafter, the following presentations will take place: Melody Shahsavarian, PhD, Digital Biologics Platform, Large Molecules Research, Sanofi, on: ‘Enhancing antibody discovery with generative AI’. Ali Madani, PhD, Founder and CEO, Profluent Bio, on: ‘Protein engineering with large language models’.

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Protein Antibody Engineer Scientist 59

Drug Discovery World

NOVEMBER 9, 2023

Novel platforms This session will begin with chariperson’s remarks from Lars Linden, PhD, Vice President, Head, Biologics Research, Bayer HealthCare, which will be followed by a keynote presentation by Agnieszka Kielczewska, PhD, Director, Research, Antibody Discovery and Screening, Biologics Discovery, Amgen.

Engineer 52

Engineer Antibody Protein In-Vivo 52

Drug Discovery World

APRIL 21, 2023

Atrandi Biosciences’ novel technology platform enables researchers to gain insights into the biology of single cells, offering immediate applications in single-cell sequencing, drug and antibody discovery, functional metagenomics, microbial analysis, directed evolution, and synthetic biology. It will be led by Björn C.

Doctors 52

Doctors Doctor Genetics In-Vitro 52

Drug Discovery World

NOVEMBER 15, 2022

Even as methods in DNA synthesis continue to advance, scientists’ reliance on third-party companies for synthesising DNA creates a bottleneck, impeding research timelines. . “If If you want to order gene-length sequences, rather than short oligos for PCR, the waiting times are around two or three weeks at least.

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DNA Drugs Antibody Engineer 98

Scienmag

APRIL 20, 2021

A new study challenges the presumption that all South-Eastern-Bantu speaking groups are a single genetic entity. Almost 80% of South Africans speak one of the SEB family languages as their first language.

Genetics 61

Genetics Research Bioinformatics Gene 61

The Pharma Data

JANUARY 10, 2021

I actually think neuroscience is going to heat up in 2021,” said Ben Zeskind , co-founder and CEO of Immuneering , which is using bioinformatics and computational biology to develop new drugs in this space, along with oncology and immuno-oncology. In a boone for Slonim’s research focus, the year 2020 has made this molecule a household name.

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Vaccination Vaccine Regulation Drugs 52

Scienmag

NOVEMBER 11, 2020

Developed by University of Toronto researchers, the new tool will enable a deeper study of stem cells and other […].

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