Drug Discovery World

OCTOBER 18, 2023

Sara Donnelly, Director of Research Planning and Business Development at PhoenixBio USA explores why the right pre-clinical model is essential for teams wanting to advance adeno-associated virus vector-based gene therapies. However, NHP models cannot fully predict AAV transduction in the human liver.

Gene Therapy 62

Gene Therapy Gene Clinical Trials Clinical Trials 62

FDA Law Blog

MARCH 13, 2023

Who better than people living with a condition to inform drug companies, physicians, academics, and the FDA on what it is like to live with their condition, what symptoms most impact their lives, what goes into their decision about whether to participate in a clinical trial, and what kind of treatment effects would be most meaningful to them?

Gene Therapy 98

Gene Therapy Gene Trials Clinical Trials 98

Bioengineer

JULY 22, 2021

Geneticists from Trinity College Dublin have discovered how a specific genetic mutation called H3K27M causes a devastating, incurable childhood cancer, known as diffuse midline glioma (DMG), and – in lab studies working with model cell types – successfully reverse its effects to slow cancer cell growth with a targeted drug.

Genetics 52

Genetics Drugs Clinical Trials Clinical Trials 52

pharmaphorum

SEPTEMBER 21, 2021

Global Gene’s Craig Martin introduces a new patient identification initiative that strives to improve diagnosis and access to clinical trials for all patients with rare CNS conditions. Doctors are often unfamiliar with these conditions. Rare diseases impact more than 30 million Americans, and 400 million people around the globe.

Gene Therapy 90

Gene Therapy Gene Clinical Trials Clinical Trials 90

Olympian Clinical Research

JUNE 2, 2021

One of the most frustrating things about atopic dermatitis is that doctors still don’t know exactly what causes the condition, which means that most treatments are centered around symptom mitigation rather than addressing the root cause. Eczema Clinical Trials In Tampa & Largo. What Causes Atopic Dermatitis?

Clinical Trials 52

Clinical Trials Clinical Trials Clinical Research Trials 52

XTalks

APRIL 6, 2022

Lung cancer is the most common cancer in men and the third most common cancer in women, according to global lung cancer statistics by the World Cancer Research Fund. The researchers observed lead times of approximately 200 days from the detection of ctDNA to cancer recurrence. Photo source: Inivata.

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DNA In-Vitro Doctors Doctor 105

XTalks

MAY 20, 2022

Do you possess laboratory skills, an analytical mindset and a penchant for research? If you enjoy working with biological samples and are enthusiastic about healthcare, a career as a clinical scientist might be just right for you. To start applying to clinical scientist jobs today, head over to the Xtalks Job Search platform.

Scientist 105

Scientist Life Science Clinical Research Doctors 105

STAT News

MARCH 6, 2023

Still, when doctors told her last year that the cancer was growing despite two operations, radiation therapy, and a fifth regimen of chemotherapy, the retired business-meeting facilitator decided to do something unorthodox: spend $83,000 out of pocket on an unproven experimental cancer vaccine.

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Vaccination Vaccine Drugs Clinical Trials 98

The Pharma Data

DECEMBER 11, 2020

And even when Black people with AML have the same access to treatment as white patients, their survival is shorter — something genetic differences might explain. The researchers said there are many potential explanations for the geographic disparity. The takeaways: Where patients live and their access to quality health care matter.

Genetics 52

Genetics Clinical Trials Clinical Trials Genetic Analysis 52

pharmaphorum

OCTOBER 6, 2022

So, when a new disease emerges, researchers have a near-impossible task working upstream from symptoms to identify the underlying cause and biological mechanisms causing disease. This problem is compounded when researchers are presented with a complex set of symptoms, with no easily identifiable infectious agent as the cause.

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In-Vivo Research Genetics Drugs 98

Olympian Clinical Research

FEBRUARY 17, 2022

However, genetic abnormalities or other health problems may be involved in the condition. When diagnosing PN, a doctor may perform a skin biopsy to look for signs of the condition, such as thickened skin and inflammation. Clinical Research on Prurigo Nodularis. Contact Olympian Clinical Research.

Clinical Trials 52

Clinical Trials Clinical Trials Clinical Research Trials 52

Olympian Clinical Research

NOVEMBER 6, 2023

While the exact cause is unknown, factors like genetics, inflammation, and hormones play a role. Apply topical medication as prescribed by your doctor if needed. Apply a topical or oral anti-inflammatory medication as prescribed by your doctor. You can contribute to this essential work by participating in our clinical trials.

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Hormones Doctors Doctor Clinical Trials 52

Drug Discovery World

APRIL 14, 2023

The American Association for Cancer Research (AACR) will honour the following cancer researchers, physician-scientists, advocates, and journalists during its annual meeting to be held April 14-19 at the Orange County Convention Center in Orlando, Florida. June’s award lecture will be held on Sunday April 16 at 4:30pm ET.

Genetics 52

Genetics Research Medicine Clinical Research 52

The Pharma Data

AUGUST 16, 2021

Researchers at the Max Planck Institute for Biophysical Chemistry in Göttingen and the Julius Maximilians University Würzburg have now elucidated the underlying molecular mechanism. If this genetic material is further replicated, defective RNA copies are produced and the pathogen can no longer spread.

RNA 52

RNA Drugs Genome Genomics 52

pharmaphorum

DECEMBER 21, 2020

As it’s just a messenger molecule, it does not affect the body’s own genetic code when it is injected as a vaccine – but what it does do is instruct cells to code for copies of a certain protein. They are very good doctors, scientists and entrepreneurs. He told pharmaphorum: “They are very good doctors, scientists and entrepreneurs.

Vaccination 111

Vaccination Vaccine Doctors Doctor 111

pharmaphorum

SEPTEMBER 17, 2020

Side-effects that caused AstraZeneca to pause its coronavirus vaccine trial are unlikely to be caused by the shot according to documents posted online and cited in other press reports – but the FDA is yet to give the go ahead for US testing to restart. Nath told CNN: “The highest levels of NIH are very concerned.

Vaccination 105

Vaccination Vaccine Trials Doctors 105

The Pharma Data

DECEMBER 17, 2020

Dr. Lisa Forbes — his doctor and co-author of a letter describing his case in the Oct. This patient had a genetic mutation that ruxolitinib is known to work on. Forbes said it’s not clear if other people with type 1 diabetes also have this specific genetic mutation. But more research is needed, she added.

Insulin 52

Insulin Genetics Doctors Doctor 52

pharmaphorum

FEBRUARY 28, 2022

However, as Ben Hargreaves discovers, research into the area has only scratched the surface, amid calls for greater funding and greater collaboration to accelerate progress. There are approximately 7,000 different types of rare disease and researchers estimate that there are more than 300 million people worldwide living with such a condition.

Gene Therapy 104

Gene Therapy Gene Development Medicine 104

XTalks

DECEMBER 20, 2023

The companies include a diverse range engaged in innovative approaches in areas like oncology, genetic medicines, inflammatory diseases, dermatology and cardiorenal therapy. 9. 10 Trends and Statistics for Clinical Trials in 2023 Several key trends in clinical trials have been shaping the landscape of the field this year.

Life Science 59

Life Science Clinical Trials Clinical Trials FDA Approval 59

The Pharma Data

MAY 9, 2022

Investigators discovered meningiomas can be divided into molecular subgroups with different clinical outcomes and recurrence rates. Currently, after surgery, doctors examine a specimen of a tumor under a microscope and grade it one, two or three in its aggressiveness. The paper was published today in Nature Genetics.

Drugs 52

Drugs Scientist DNA Genetics 52

Drug Discovery World

SEPTEMBER 5, 2022

The discovery was made by researchers at Washington University School of Medicine in St Louis, Grenoble Alpes University in Grenoble in France, and The University of Texas MD Anderson Cancer Center in Houston. Tumours (yellow) pervade the lungs of mice genetically prone to small cell lung cancer (left) on this computed tomography scan.

Protein 52

Protein Drugs Medicine Research 52

Olympian Clinical Research

SEPTEMBER 16, 2021

Similar to a majority of autoimmune diseases, the cause is most likely genetic, but environmental triggers are required to initiate disease activity. . In addition, your child’s doctor will likely recommend an antihistamine , which is a kind of drug that treats allergies to help with itching. Contact Olympian Clinical Research .

Clinical Research 52

Clinical Research Allergies Development Doctors 52

Bioengineer

JULY 23, 2021

In the evolving field of cancer biology and treatment, innovations in organ-on-a-chip microdevices allow researchers to discover more about the disease outside the human body. Researchers then can recreate events within platelets circulating in the blood as they approach the tumor and make it more potent and metastatic. ” ###.

Engineer 52

Engineer Gene Editing Clinical Trials Clinical Trials 52

XTalks

SEPTEMBER 22, 2020

“Helping people understand and manage their heart health has always been a priority for Fitbit, and our new ECG app is designed for those users who want to assess themselves in the moment and review the reading later with their doctor,” Eric Friedman, Fitbit co-founder and CTO said in a statement.

Gene 107

Gene Doctors Doctor Clinical Trials 107

pharmaphorum

NOVEMBER 10, 2022

Wanting next to explore the place of research in this discussion of equity and innovation excellence, he invited Catherine Elliott to speak. And in the UK over 30% of clinical trials funded has one European partner at least. After all, cancer research is global and innovation, too, is global.

Nurses 97

Nurses Research Clinical Trials Clinical Trials 97

XTalks

JUNE 8, 2021

In addition, recent data from a Phase I trial has shown ‘remarkable’ long-term results of the gene therapy in children with the disease. The prevalence of SMA is about one in 10,000 children, and one in 54 people carry the SM1 genetic mutation; two carriers have a 25 percent chance of having a child with SMA.

Gene Therapy 110

Gene Therapy Gene Protein Trials 110

pharmaphorum

APRIL 8, 2021

COVID-19 has been a trial-by-fire showing just how quickly drugs and vaccines can be developed under the right circumstances – but there is much to do to ensure this progress is not lost, said speakers at WIRED Health 2021, including the CEOs of BioNTech and BenevolentAI. . Data is the lifeblood of AI-powered research.

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Development Drugs Vaccination Vaccine 93

pharmaphorum

AUGUST 25, 2022

That was until my doctors stunned me with the news that I had cirrhosis caused by non-alcoholic steatohepatitis, or NASH, a severe form of fatty liver disease that often has few or no symptoms until very late stages. Cirrhosis is not just an “old drunk guys” disease, a stigma which has long hampered interest and investment in research.

Development 98

Development Drugs Trials Medicine 98

XTalks

FEBRUARY 4, 2021

Data generated through high-throughput omics approaches paired with clinical patient records can give rise to remarkably robust datasets to inform and guide disease insights and development of targeted therapeutics. Generation of strong research dataset cohorts must begin with high-quality clinical samples.

Research 98

Research Biobanking Drugs Genome 98

pharmaphorum

JANUARY 29, 2021

This has, of course, garnered immense excitement – Doctors Emmanuelle Charpentier and Jennifer Doudna were named winners of the Nobel Prize for chemistry in recognition of their discovery of CRISPR/Cas9 gene editing technology. And ultimately we will be able to add genetic influences to diseases that don’t have a genetic cause.

Gene Editing 145

Gene Editing Gene Gene Therapy In-Vivo 145

pharmaphorum

FEBRUARY 26, 2021

Every time a patient with a rare condition walks into a hospital, doctors face the probable challenge of starting from scratch. Here are the challenges that the medical community faces, most of which relate to the lack of research data, high cost of developing treatments or orphan drugs and greater chances of failure. .

Drugs 78

Drugs Genome Project Genome Genomics 78

pharmaphorum

JUNE 18, 2021

This mission saw him become a diplomat in the Middle East, a McKinsey consultant in Asia, and take on roles in international intelligence before realizing he could use his knowledge and skills in solving complex problems to crack one of healthcare’s greatest challenges—accelerating clinical trials. positioned to rise to the challenge.

Clinical Trials 52

Clinical Trials Clinical Trials Trials Big Data 52

The Pharma Data

NOVEMBER 27, 2020

The hand-held testing device uses lateral flow – like a home pregnancy test – to detect the virus’s interaction with sugars around human cells, so that nurses, doctors and patients can all easily perform the test without any prior training and at any location. .

Vaccination 52

Vaccination Vaccine Immune Response Marketing 52

The Pharma Data

NOVEMBER 18, 2020

The California company said that clinical trials showed 100% of patients were able to perform the Lucira test in about two minutes. Lab tests that look for the coronavirus’s genetic material using a technique called polymerase chain reaction (PCR) are still considered the gold standard for detecting the virus.

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FDA Approval Vaccination Vaccine Genetics 52

Drug Discovery World

AUGUST 16, 2022

Disparities resulting from genetic, environmental, social, and economic factors increase cancer risks in certain subpopulations, and negatively affect their health outcomes. Research supporting a better understanding of how these factors intersect continues to be critical in addressing and eliminating cancer-related disparities.” .

Research 52

Research Clinical Trials Clinical Trials Trials 52

Roots Analysis

SEPTEMBER 1, 2023

Real World Data and Blue Ocean Strategy Real-world data is particularly useful for researchers, as it provides valuable insights from patient data and knowledge that can impact many decision-making processes. Streamlining Supply Chain Management The digital field is making a relevant move in the pharmaceutical industry in more than one field.

Drug Delivery 52

Drug Delivery Marketing Drug Delivery Systems Drugs 52

pharmaphorum

SEPTEMBER 12, 2022

Across LabCorp , we innovate through science and technology, with access to approximately 2,500 [doctors] and PhDs and over 700 patients. Everyone’s genetic makeup differs, and each person’s cancer experience is unique to them – how cancer develops, how fast it spreads, which drugs it responds to, and more. Tailored oncology.

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Genome Genomics Clinical Trials Clinical Trials 105