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Risk Assessment for use of Engineered Genetic Materials in Clinical Research

Advarra

The use of engineered genetic materials in clinical trials is rapidly expanding, with potential applications for genetic vaccines, gene-modified cellular therapies, and gene therapies. A key part of the IBC’s evaluation is assessing the risks posed by the engineered genetic materials. Why Does the IBC Need to do a Risk Assessment?

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Engineers create a programmable fiber

Scienmag

In a first, the digital fiber contains memory, temperature sensors, and a trained neural network program for inferring physical activity Credit: Image: Anna Gittelson. Photo by Roni Cnaani. MIT researchers have created the first fiber with digital capabilities, able to sense, store, analyze, and infer activity after being sewn into a shirt.

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Pharmaceutical processing: Why the industry is turning to turnkey

Pharmaceutical Technology

According to Adam Bradbury, GlobalData PharmSource analyst “[…] evidence indicates that containment facilities are in high demand and will be increasingly so in future as the oncology pipeline and the use of cytotoxic drugs continues to grow.” These turnkey solutions cover every process through the drug manufacturing life cycle.

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MIT engineers make filters from tree branches to purify drinking water

Scienmag

Fuller, Sayo Studio The interiors of nonflowering trees such as pine and ginkgo contain sapwood lined with straw-like conduits known as xylem, which draw water up through a tree’s trunk and branches. Prototypes tested in India show promise as a low-cost, natural filtration option Credit: Courtesy: N.R.

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‘Smart drugs’ may contain unapproved pharmaceuticals, according to a new study

The Pharma Data

Photo by Raysonho @ Open Grid Scheduler / Grid Engine. Some supplements billed as ‘smart drugs’ may contain unapproved drugs in potentially dangerous combinations and doses, according to a new study. The FDA may take action against a supplement maker after a product is on the market if it is mislabelled or contains unapproved drugs.

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Engineering an “invisible cloak” for bacteria to deliver drugs to tumors

The Pharma Data

Columbia Engineering researchers report that they have developed a “cloaking” system that temporarily hides therapeutic bacteria from immune systems, enabling them to more effectively deliver drugs to tumors and kill cancer cells in mice. Sheng Professor of Biomedical Engineering. ” An Effective On/Off Switch.

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Batteryless and wireless device detects coronavirus with magnetostrictive composite plates

Medical Xpress

What if you could tell if your surroundings contained COVID-19 particles or droplets the moment they or you entered the vicinity? A research group has engineered a batteryless, self-powering device that can wirelessly transmit the detection of coronavirus in the air. This is now closer to reality.