Drug Discovery World
FEBRUARY 15, 2024
The RNA technology company conducted the work in collaboration with the lab of Professor De Geest at Ghent University, and describes how delivery of mRNA encoded antigens in LNPs comprising a novel class of ionisable lipids enhances the induction of antigen-specific immune responses while reducing undesired off-target expression in the liver, thereby (..)
World of DTC Marketing
DECEMBER 29, 2020
OBSERVATION: Biologics can take a long time to develop but COVID vaccines have been in development for almost 50 years and novel approaches were used to develop these vaccines. Vaccines typically take 10 to 15 years to develop, test and release to the public. The post How did pharma develop a vaccine so quickly?
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STAT News
DECEMBER 13, 2022
Medicines that reshape or tamp down immune responses may be life-changing for patients with cancer and autoimmune disorders, but in some cases they can awaken a dormant virus and unleash a deadly brain disease. A new study suggests that the root of the problem is buried in our genetic code. Read the rest…
Scienmag
MARCH 15, 2021
Engineered T cells can recognize and destroy cells with loss of one gene copy Credit: Elizabeth Cook Researchers developed a prototype for a new cancer immunotherapy that uses engineered T cells to target a genetic alteration common among all cancers.
Cloudbyz
MARCH 5, 2024
In the intricate dance of drug discovery and development, two protagonists emerge as the cornerstones of modern medicine: biologics and small molecules. They are often used to mimic or enhance natural biological processes, such as immune responses. Their small size allows them to distribute widely throughout the body.
Drug Discovery World
MAY 29, 2024
Marc Hummersone, Senior Director of Research and Development (R&D) at Astrea Bioseparations, shares insight on the challenges and opportunities in cell and gene therapy (CGT) with DDW’s Megan Thomas. That takes a lot of effort, and some very clever people to get that amount of genetic information into a single plasmid DNA.
Camargo
JULY 27, 2021
How and When to Incorporate PK Design into Your Gene Therapy Development Plan. Similarly, DNA molecules can be genetically modified and introduced into human cells, or individual patient cells can be genetically modified and reintroduced to the body. PK Planning for Gene Therapy Development Programs.
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