Drug Discovery World

NOVEMBER 7, 2022

In 2018, the UK’s department of health announced an NHS Genomic Medicine Service, which allows patients with rare diseases to have their entire genetic code read in the hope of providing a much-needed diagnosis. That said, some people with rare genetic diseases remain without a molecular diagnosis after their genome is analysed. . “We

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Genome Genomics Genetics Genetic Disease 52

XTalks

APRIL 6, 2022

Cancerous cells and tumors release small fragments of DNA into the bloodstream called circulating tumour DNA (ctDNA). The researchers at the Cancer Research UK Cambridge Institute published this data from the LUng cancer CIrculating tumour DNA (LUCID) study in the journal Annals of Oncology.

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DNA In-Vitro Doctors Doctor 105

The Pharma Data

MAY 9, 2022

Currently, after surgery, doctors examine a specimen of a tumor under a microscope and grade it one, two or three in its aggressiveness. The paper was published today in Nature Genetics. “Eventually we hope to tailor medical therapy to the genetic changes within each individual person’s meningioma,” Magill said.

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Drugs Scientist DNA Genetics 52

pharmaphorum

JANUARY 20, 2021

Ella, 28, was diagnosed with cystic fibrosis – a rare genetic disease which causes a build-up of thick, sticky mucus in the lungs, digestive tract, and sinuses – at 18 months old. This sticky mucus gets trapped and breeds infections from bacteria I inhale,” says Ella, who adds she was “terrified” of doctors as a child.

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Bacteria Bacterium DNA Doctors 102

pharmaphorum

DECEMBER 21, 2020

Their technology is based on synthetic messenger RNA – short for ribose nucleic acid – which is a short transcript of a longer DNA code. As it’s just a messenger molecule, it does not affect the body’s own genetic code when it is injected as a vaccine – but what it does do is instruct cells to code for copies of a certain protein.

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Vaccination Vaccine Doctors Doctor 90

XTalks

AUGUST 10, 2021

SHERLOCK is based on the CRISPR “molecular scissors” system involving a Cas enzyme that cuts DNA or RNA at specific locations, but with an additional snippet: upon recognizing its target sequence, the specially designed scissors also cut single-stranded engineered fluorescent DNA probes in the surrounding area. miSHERLOCK Workflow.

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XTalks

FEBRUARY 4, 2021

Bernard, executive vice president for research and chief research officer at Vanderbilt University Medical Center, shared his experience in helping set up a DNA and clinical data resource called BioVU. The project began in 2004, in the early days of biobanking for DNA, says Dr. Bernard, and has grown tremendously since.

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Research Biobanking Drugs Genome 98

pharmaphorum

NOVEMBER 3, 2020

Allison’s son David was just six when he started displaying the symptoms of (R)20, a genetic condition that can cause multiple, uncontrollable seizures, declines in cognition and mobility, and terrifying hallucinations. There are no clinical practice guidelines, meaning doctors treat on a case-by-case basis.

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Gene Sequencing Gene Genome Genomics 111

Drug Discovery World

SEPTEMBER 5, 2022

Tumours (yellow) pervade the lungs of mice genetically prone to small cell lung cancer (left) on this computed tomography scan. One of the challenges we will face is convincing doctors to go back to an old drug. Hindering this repair process makes the drug much more effective. .

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Protein Drugs Medicine Research 52

pharmaphorum

JANUARY 29, 2021

‘Cutting edge’ is, for once, a truly apt description when it comes to gene editing – both because the field is pushing medicine into areas we might never have dreamed possible, and because these technologies involve literally cutting DNA at a specific point in the genome. The company’s primary technology is its zinc finger (ZF) platform.

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The Pharma Data

JANUARY 11, 2021

While the blueprint is a genetic code, it never enters the nucleus of the cells. “That means it never converts into DNA,” Dr. M. People who have had allergic reactions to other vaccines should ask their doctor about taking the COVID-19 vaccine. said in a health system news release.

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Drug Discovery World

JUNE 5, 2023

Megan Thomas caught up with Debora Lucarelli, CEO of Enhanc3D Genomics, to learn more about the company. She said: “We are a functional genomics company with a proprietary platform that allows us to charter the non-coding DNA, from which we extract a lot of valuable information to identify novel targets and biomarkers.

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Genome Genomics Life Science Genetics 52

Drug Discovery World

OCTOBER 18, 2023

in Cell Biology and Biochemistry from University College London and was a post-doctoral fellow at Albert Einstein College of Medicine in New York City. Such therapies have become an appealing drug modality for multiple conditions, including monogenic disorders, cancers, and infectious diseases. She received a Ph.D. References 1: U.S.

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Gene Therapy Gene Clinical Trials Clinical Trials 64

Drug Discovery World

APRIL 14, 2023

He is being recognised for his revolutionary contributions to developing the first gene-edited cell-based therapy for cancer that involves the genetic re-engineering of a patient’s own T cells to combat their disease, and for demonstrating that adoptive T-cell therapy can induce remission and in some cases cure patients with advanced cancer.

Genetics 52

Genetics Research Medicine Clinical Research 52

XTalks

FEBRUARY 26, 2021

Hollmann was a doctor at the Kalihi Hospital in Hawaii who wanted to find a way to extract the active ingredients of chaulmoogra oil so that it could be effectively administered to patients. He even became known as the “the plant doctor” among local farmers as he had the ability to improve the health of their fields, orchards and gardens.

Scientist 69

Scientist Research Genetics Cosmetics 69

pharmaphorum

SEPTEMBER 13, 2022

Thanks to the dedicated efforts of doctors, patients, carers, and healthcare professionals, people diagnosed with blood cancer are now living longer, with a steady stream of more effective treatments entering the market each year. This was an entirely new approach to DNA research. 2012 – The 100,000 Genomics Project begins.

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Genome Project Genome Genomics DNA 94

The Pharma Data

JANUARY 21, 2021

The test valuates mitochondrial DNA levels. When mitochondrial DNA, normally found inside cells, in the mitochondria, spills into the bloodstream, it signals that a particular type of violent cell death is occurring. They measured the patients’ mitochondrial DNA levels on the first day of their hospital stays.

Research 52

Research DNA Hormones Vaccination 52

The Pharma Data

MAY 13, 2021

Brace Yourself: What I am about to share with you goes AGAINST what all the popular nutritionists, diet experts, and doctors will tell you to do. The REAL problem lies in the fact that most of the foods we eat today have been Genetically Modified. So, be prepared. I’m not here to use scare tactics. A better definition of a G.M.O.

Production 52

Production Containment Genetics Doctors 52

XTalks

OCTOBER 1, 2020

In the beginning, I always thought I wanted to be a doctor, but then I felt it was very depressing, particularly at that time and in that particular field. So, I [decided] to go into research rather than be a doctor and see patients [such as that] young, beautiful life that you could do nothing about it.”.

Scientist 52

Scientist In-Vitro Research Life Science 52

Drug Discovery World

NOVEMBER 9, 2023

Klaus Wagenbauer, PhD, Founder & CEO, Plectonic, on: ‘Programmable DNA-origami-based T cell engagers: PTE’. Alessa Schaffrath, Doctoral Student, UKE Hamburg, on: ‘Transgenic llama mice – a fast and flexible single domain discovery tool’.

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Engineer Antibody Protein In-Vivo 52

XTalks

SEPTEMBER 14, 2020

CanSino Biologics is developing a vaccine that involves snipping a bit of the virus’ genetic code off and coupling it with a harmless virus to provoke a SARS-CoV-2 immune response. Several laboratories have already shown that they can detect genetic material from the virus in wastewater.

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Vaccination Vaccine Antibody Life Science 92