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VCU technology could upend DNA sequencing for diagnosing certain DNA mutations

Scienmag

Credit: John Wallace, VCU Massey Cancer Center Doctors are increasingly using genetic signatures to diagnose diseases and determine the best course of care, but using DNA sequencing and other techniques to detect genomic rearrangements remains costly or limited in capabilities.

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$8 million awarded to landmark genetic research project

Drug Discovery World

Landmark genetic research could allow doctors to accurately predict whether a patient is at risk of developing common diseases, decades before any symptoms would become evident. His research focuses on people from diverse backgrounds to ensure life-saving medical advances are accessible to everyone – a key issue for Snow Medical.

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DNA test can quickly identify pneumonia in patients with severe COVID-19, aiding faster treatment

Scienmag

Researchers have developed a DNA test to quickly identify secondary infections in COVID-19 patients, who have double the risk of developing pneumonia while on ventilation than non-COVID-19 patients.

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Novel biosensor could help optimise cancer treatment

Drug Discovery World

Scientists from Korea have developed a new biosensor that uses fluorescence resonance energy transfer (FRET) to detect DNA double-strand breaks in living specimens in real time. This biosensor has the potential to aid the development of new treatments for DNA damage-related diseases by revealing how our bodies repair damaged DNA.

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Personalized Blood Test Detecting ctDNA Can Help Predict Lung Cancer Relapse

XTalks

Lung cancer is the most common cancer in men and the third most common cancer in women, according to global lung cancer statistics by the World Cancer Research Fund. Cancerous cells and tumors release small fragments of DNA into the bloodstream called circulating tumour DNA (ctDNA).

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A different approach: reimagining biology

Drug Discovery World

Three key members of the team – Dr Raquel Sanches-Kuiper, Vice President of Technology, Dr Matthew Hayes, Chief Technology Officer and John Edgell, Head of Cloud Engineering – explain how the company is doing this and what it means for the advancement of DNA synthesis in the lab. The collaboration has been very successful.

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Genetic biomarkers could personalise therapy for TNBC

Drug Discovery World

The study, by researchers at The Institute of Cancer Research, London, shows that certain characteristics within patients’ primary tumours can predict how they will respond to different treatments after their tumours have spread around the body.